Scholars from the University of Cambridge found that 1-methylΨ modification can lead to +1 frameshifting and off-target T-cell immune responses, suggesting a potential "defect" in mRNA vaccine technology.
Dec 28, 2023
Non-coding sequences also play a significant role, as scholars from Sun Yat-sen University may develop a novel cancer immunotherapy from them.
Nov 29, 2023
Scientists are revolutionizing genome editing with Phage-Assisted Continuous Evolution (PACE), creating compact, efficient prime editors.
Oct 07, 2023
Caltech researchers developed an engineered RNA output system called COURIER as a new tool for cell biology and medical research.
Aug 27, 2023
Researchers find a proteasome regulator that influences proteasome activity and antigen diversity, weakening antitumor immunity.
Jul 17, 2023
Researchers develop personalized mRNA vaccines based on each patient's genetic makeup to fight pancreatic cancer.
Jun 19, 2023
Researchers are investigating why antibodies seem to recognize certain parts of antigens more readily than others.
May 25, 2023
A new method was developed to predictably and finely down-regulate the protein expression of target genes.
Apr 19, 2023