irs4.S cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	irs4.S
Entrez Gene ID	399388
Full Name	insulin receptor substrate 4 S homeolog
Synonyms	irs2,irs2-a,irs4
General protein information	Preferred Names insulin receptor substrate 4 S homeolog Names insulin receptor substrate 2-A IRS-2-A insulin receptor substrate protein insulin receptor substrate-undetermined designation insulin receptor substrate-unique xIRS-u
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001090773.1	NP_001084242.1	insulin receptor substrate 2-A

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

A novel insulin receptor substrate protein, xIRS-u, potentiates insulin signaling: functional importance of its pleckstrin homology domain.
Ohan N, Bayaa M, Kumar P, Zhu L, Liu XJ
Molecular endocrinology (Baltimore, Md.)12(8)1086-98(1998 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following irs4.S gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the irs4.S cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf01384	NM_001090773.1 Latest version!	Xenopus laevis insulin receptor substrate 4 S homeolog (irs4.S), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

irs4.S ( NM_001090773.1 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001084242.1 Xenopus laevis insulin receptor substrate 4 S homeolog (irs4.S), mRNA.

Price & Availability↑

CloneID	OAf01384
Clone ID Related Accession (Same CDS sequence)	NM_001090773.1
Accession Version	NM_001090773.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3225bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Xenopus laevis(African clawed frog)
Product	insulin receptor substrate 2-A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC072768.1. On Jul 25, 2007 this sequence version replaced NM_001090774.1. ##Evidence-Data-START## Transcript exon combination :: BC072768.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00012418, SAMD00012420 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGTG TGCTGTGTCC TACTGAAGAG GACAGATCGA GTCGAGCAGC CTTGAGAATG 
CTTCCCCCGC AGCCGTGTCC AGATGAGAGC GGCGCATACA GGCGGATGTC TGGACCGACG 
CTGTCGCAGG TGCAGGAGGA ACCGGCAGCC GAACCCCCGC AGCCGCCGGC ATCCGCCGCG 
GAGGATGATG TGAGGAAACG CGGCTACCTG CGAAAGCAGA AGCACGGACA CAAGCGCTAC 
TTCGTGCTGC GGAGCCAGAG CCACCTGGGT CCCGCCCGGC TCGAGTACTA CGACAACGAG 
AAGAAGTTCC GGAGCGGACA ACGGAGCGGC TGCCACCCCA AGAGAGTCAT CCCGCTGTAC 
CTGTGTTTCA CAGTCAGCCG GCGGGCAGAT GCCAAAAACA AGCACCTCGT GGCTCTCTAC 
ACCAAGGACG AGTACTTCGC TATGGCGGCA GAGAACGAAC AGGAGCAGGA CGGCTGGTAC 
CAGGCCCTCA GCGAGCTCAT CAATGAGAGC AAGGGCGCCT GCCTGGACAC CGAGGAGCTG 
GAGGAGAACT ACGGCACCCT GAGGCCGGGC ACTGTATTCA AAGAGGTGTG GCAGGTAAAC 
GTGAAGCCCC GAGGGCTGGG TCAGGCCAAG AATCTGTCGG GGGTCTATCG CTTGTGTCTG 
TCCAGCAAGG CGGTGCATCT GGTCAAGCTG AACTCGGATG TAGCCTGTGT CCATCTGCTG 
CTCATGAACA TCCGCCGCTG TGGCCACTCC GAGAACTACT TCTTCATTGA GGTGGGTCGC 
TCCTCCTCCA CCGGGGCAGG TGAGCTGTGG ATGCAGGTGG ATGACTGTGT GGTGGCGCAG 
CACATGCACG AGACCTTCCT AGACACCATG AAGGCTCTGA AGGCCTATTC GGAATTCAGG 
CCCCGGAGTA AGAGCCAGTC CTCCTGCACA AATCCCATCT CTTTCATCAC CACCAGAAGG 
TACTTGGGCA ACCTGCCCCC CAGCCAGACT GGACTGCAGA GAAGGGCCAG GACTGAGAGT 
ATGGTGGGAA CACCCCCCTC TGCTAAGAAT AATTCTTTTC GTTTTAGAAC CTCCAGTGAA 
GGAGAGGGTA CAATGACCAG ACCTTTCAGG TCTGTGACTG GGAGTCTGAG CCATTTAAAC 
ACGGCAAGGA TTAACCTGGG AAAGCAAGAA GGAGCTGGGA GGTATGTCAG AGCACCTTTT 
AATTCTGGAT ACCAGTCCAG GTCGGCCTCA TTACCTGTGT CTCATTTCCC ATCTGCCACC 
AGTCCTATAA GTGTGTGCTC TAGCAGCGGG CATGGGTCTG CATCTGAAAC GCTGACCAGG 
CCATCTAGTT CCTCTGTTTG TGGATCTCCT AGTGATGGTG GGTTTATTTC CTCTGATGAA 
TATGGTTCAA GCCCTGGTGA CCTGAGGTAC TTCCGGGTTA GAAGTAATAC CCCTGATTCC 
TTGGGAAATA CACCTCCCAT ACAGGAAGAG AACACATTGA GTGACTACAT GTCAATGAGC 
ACACACAGCC AGCCAGATTC TAGGGACGAT TATATGGAAG CTGATAAATG TTTTAGGAAA 
AGGACATACT CCCTAACAAA ACATACAAAC TCTGCATCCA AGCAAAAGTC CCAGACTGCA 
ATTTCTTTGG GGGAGGACTC AGAAGAGATT AATAAACAGT TTGCCTTTGC TGAATCACCA 
AAGCTGAAAG ATAGTAGTCT TGTAGATGAT TATAGTAATG GTGTAATAGA TTCTGTTTGT 
AACCAAAGCA GAAGTAAAGC TAGTGATGAT GGCTACATGC CAATGATGCC TTCTAATTTA 
TATGACAGTG ACTACTTACC CATGGCCCCA AAAACTGTGT CTGCACCAAA ACAAATTAAT 
AGGTGTCCTT CTCAGGCAGA CTCTAAGGGT TATATGATGA TGTTTCCCAT TAATAGTTCA 
CCTGTCAAAA ATGTATTTGG AGGGGCTGCT ACTAAAAGTA ACCTTGAAAA ACTGAGTAAT 
GGAGGCTACA TGGACATGTC ATATGGGAAC TCCACAAAAC AAATTCATGA CTCTAATTTA 
AATAATAATT CTAGGGGGTT GAGTTCTTAT TTTTCCCTGC CTAGGAGCTT TAAAAGCTTA 
ACTAAGCAGA CCACAGATCA AAATGAATAT GTTCCAATGT CCTCACCTGG AAAGCTGCTG 
CATTTGGGTG CAGAAAATGG AGTGGATGTT TGTAAGGATG GAGCAGTTCA TGATATAGCT 
AAGATTGAAT TAAAATCTTC CAGTAGCATA CTGGATCAAC AAGTTAAAAG GCCAAATAAA 
CTTACTCTAG GCATCAGGGG AAGTAATACC ATACCAAGAA TGTTTGATCA CTCTGCTCCA 
GCTGAACCTA CTAGCCCTGG AGAGTATATA AACATCGACT TTAGTGATAA AGCAAGTAGT 
ACTCCATATT CACTATCTGC TGATGGGTCA CCTTCCTCTC TTGGGTCAAG CTGTGATCAT 
CGTCAGTCTC CGTTATCTGA TTACATGAGT GTGGATATTG ATGTACAGTC TCCAAAAGCA 
ACGGCAGAAC AGTCTAACTC TTTAACAGAC ATTTCATTAT ATGCATGCAC TGTTGTCTCT 
AGAATGCAGC CAAATGCTGA ATATGCCAAG CTTCCCTGTG GTACAGCTTG TGTCAGCAAA 
ACGGACAACA TAATGGATGA TTACACCACA ATGACTTTTA ACATGGCAAT GACTCCACCA 
AGATCCTTTG CCAGTGAAAC AGAGAATGGT ACAAAAGTGG ACAGTCCTTC ATCCATTGTG 
AATCGGTTGT GTATAGGGGA ATTGACTTCT CTTAACAGTG GCTTTTCTTT ACCAAATCCT 
TTGCCTGAAC CTATAGCTGG GCCTAAAGTT ATCCGTGCAG ACTCACAGGG AAGGCGAAGG 
CACAGTTCTG AAACTTTTGC CTCTTCCAGC ACGGTGACCA CTTCCTCTTC TTGCTTTACT 
GAAAGTGGCA AGAGGCACAG CTCAGCCTCA TTTGACAATG TATGGCTTAA ACCTGATGAA 
AACAGTTGTG AACAAGAGAA TAAAATGTCC AGGCATTGCT CAACAGGATT TCAGAATGGG 
TTAAACTACA TCTCTTTGAG TATGCACAAT GGTGTTTGTG AACCAACGTC CCCAGATTGC 
CATCAGCACC AAAACGGAAG TAGAAATCTG GAGAGTGGGG GTTATGTCAG CATCGACTTC 
ACAAGGTGTG ACTGTCTGAA GTGTCCCACT TCAAGAAAAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001084242.1
CDS	247..3471
Translation	MAGVLCPTEEDRSSRAALRMLPPQPCPDESGAYRRMSGPTLSQVQEEPAAEPPQPPASAAEDDVRKRGYLRKQKHGHKRYFVLRSQSHLGPARLEYYDNEKKFRSGQRSGCHPKRVIPLYLCFTVSRRADAKNKHLVALYTKDEYFAMAAENEQEQDGWYQALSELINESKGACLDTEELEENYGTLRPGTVFKEVWQVNVKPRGLGQAKNLSGVYRLCLSSKAVHLVKLNSDVACVHLLLMNIRRCGHSENYFFIEVGRSSSTGAGELWMQVDDCVVAQHMHETFLDTMKALKAYSEFRPRSKSQSSCTNPISFITTRRYLGNLPPSQTGLQRRARTESMVGTPPSAKNNSFRFRTSSEGEGTMTRPFRSVTGSLSHLNTARINLGKQEGAGRYVRAPFNSGYQSRSASLPVSHFPSATSPISVCSSSGHGSASETLTRPSSSSVCGSPSDGGFISSDEYGSSPGDLRYFRVRSNTPDSLGNTPPIQEENTLSDYMSMSTHSQPDSRDDYMEADKCFRKRTYSLTKHTNSASKQKSQTAISLGEDSEEINKQFAFAESPKLKDSSLVDDYSNGVIDSVCNQSRSKASDDGYMPMMPSNLYDSDYLPMAPKTVSAPKQINRCPSQADSKGYMMMFPINSSPVKNVFGGAATKSNLEKLSNGGYMDMSYGNSTKQIHDSNLNNNSRGLSSYFSLPRSFKSLTKQTTDQNEYVPMSSPGKLLHLGAENGVDVCKDGAVHDIAKIELKSSSSILDQQVKRPNKLTLGIRGSNTIPRMFDHSAPAEPTSPGEYINIDFSDKASSTPYSLSADGSPSSLGSSCDHRQSPLSDYMSVDIDVQSPKATAEQSNSLTDISLYACTVVSRMQPNAEYAKLPCGTACVSKTDNIMDDYTTMTFNMAMTPPRSFASETENGTKVDSPSSIVNRLCIGELTSLNSGFSLPNPLPEPIAGPKVIRADSQGRRRHSSETFASSSTVTTSSSCFTESGKRHSSASFDNVWLKPDENSCEQENKMSRHCSTGFQNGLNYISLSMHNGVCEPTSPDCHQHQNGSRNLESGGYVSIDFTRCDCLKCPTSRKD

Target ORF information:

RefSeq Version	NM_001090773.1
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis insulin receptor substrate 4 S homeolog (irs4.S), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001090773.1

ORF Insert Sequence:

ATGGCGGGTG TGCTGTGTCC TACTGAAGAG GACAGATCGA GTCGAGCAGC CTTGAGAATG 
CTTCCCCCGC AGCCGTGTCC AGATGAGAGC GGCGCATACA GGCGGATGTC TGGACCGACG 
CTGTCGCAGG TGCAGGAGGA ACCGGCAGCC GAACCCCCGC AGCCGCCGGC ATCCGCCGCG 
GAGGATGATG TGAGGAAACG CGGCTACCTG CGAAAGCAGA AGCACGGACA CAAGCGCTAC 
TTCGTGCTGC GGAGCCAGAG CCACCTGGGT CCCGCCCGGC TCGAGTACTA CGACAACGAG 
AAGAAGTTCC GGAGCGGACA ACGGAGCGGC TGCCACCCCA AGAGAGTCAT CCCGCTGTAC 
CTGTGTTTCA CAGTCAGCCG GCGGGCAGAT GCCAAAAACA AGCACCTCGT GGCTCTCTAC 
ACCAAGGACG AGTACTTCGC TATGGCGGCA GAGAACGAAC AGGAGCAGGA CGGCTGGTAC 
CAGGCCCTCA GCGAGCTCAT CAATGAGAGC AAGGGCGCCT GCCTGGACAC CGAGGAGCTG 
GAGGAGAACT ACGGCACCCT GAGGCCGGGC ACTGTATTCA AAGAGGTGTG GCAGGTAAAC 
GTGAAGCCCC GAGGGCTGGG TCAGGCCAAG AATCTGTCGG GGGTCTATCG CTTGTGTCTG 
TCCAGCAAGG CGGTGCATCT GGTCAAGCTG AACTCGGATG TAGCCTGTGT CCATCTGCTG 
CTCATGAACA TCCGCCGCTG TGGCCACTCC GAGAACTACT TCTTCATTGA GGTGGGTCGC 
TCCTCCTCCA CCGGGGCAGG TGAGCTGTGG ATGCAGGTGG ATGACTGTGT GGTGGCGCAG 
CACATGCACG AGACCTTCCT AGACACCATG AAGGCTCTGA AGGCCTATTC GGAATTCAGG 
CCCCGGAGTA AGAGCCAGTC CTCCTGCACA AATCCCATCT CTTTCATCAC CACCAGAAGG 
TACTTGGGCA ACCTGCCCCC CAGCCAGACT GGACTGCAGA GAAGGGCCAG GACTGAGAGT 
ATGGTGGGAA CACCCCCCTC TGCTAAGAAT AATTCTTTTC GTTTTAGAAC CTCCAGTGAA 
GGAGAGGGTA CAATGACCAG ACCTTTCAGG TCTGTGACTG GGAGTCTGAG CCATTTAAAC 
ACGGCAAGGA TTAACCTGGG AAAGCAAGAA GGAGCTGGGA GGTATGTCAG AGCACCTTTT 
AATTCTGGAT ACCAGTCCAG GTCGGCCTCA TTACCTGTGT CTCATTTCCC ATCTGCCACC 
AGTCCTATAA GTGTGTGCTC TAGCAGCGGG CATGGGTCTG CATCTGAAAC GCTGACCAGG 
CCATCTAGTT CCTCTGTTTG TGGATCTCCT AGTGATGGTG GGTTTATTTC CTCTGATGAA 
TATGGTTCAA GCCCTGGTGA CCTGAGGTAC TTCCGGGTTA GAAGTAATAC CCCTGATTCC 
TTGGGAAATA CACCTCCCAT ACAGGAAGAG AACACATTGA GTGACTACAT GTCAATGAGC 
ACACACAGCC AGCCAGATTC TAGGGACGAT TATATGGAAG CTGATAAATG TTTTAGGAAA 
AGGACATACT CCCTAACAAA ACATACAAAC TCTGCATCCA AGCAAAAGTC CCAGACTGCA 
ATTTCTTTGG GGGAGGACTC AGAAGAGATT AATAAACAGT TTGCCTTTGC TGAATCACCA 
AAGCTGAAAG ATAGTAGTCT TGTAGATGAT TATAGTAATG GTGTAATAGA TTCTGTTTGT 
AACCAAAGCA GAAGTAAAGC TAGTGATGAT GGCTACATGC CAATGATGCC TTCTAATTTA 
TATGACAGTG ACTACTTACC CATGGCCCCA AAAACTGTGT CTGCACCAAA ACAAATTAAT 
AGGTGTCCTT CTCAGGCAGA CTCTAAGGGT TATATGATGA TGTTTCCCAT TAATAGTTCA 
CCTGTCAAAA ATGTATTTGG AGGGGCTGCT ACTAAAAGTA ACCTTGAAAA ACTGAGTAAT 
GGAGGCTACA TGGACATGTC ATATGGGAAC TCCACAAAAC AAATTCATGA CTCTAATTTA 
AATAATAATT CTAGGGGGTT GAGTTCTTAT TTTTCCCTGC CTAGGAGCTT TAAAAGCTTA 
ACTAAGCAGA CCACAGATCA AAATGAATAT GTTCCAATGT CCTCACCTGG AAAGCTGCTG 
CATTTGGGTG CAGAAAATGG AGTGGATGTT TGTAAGGATG GAGCAGTTCA TGATATAGCT 
AAGATTGAAT TAAAATCTTC CAGTAGCATA CTGGATCAAC AAGTTAAAAG GCCAAATAAA 
CTTACTCTAG GCATCAGGGG AAGTAATACC ATACCAAGAA TGTTTGATCA CTCTGCTCCA 
GCTGAACCTA CTAGCCCTGG AGAGTATATA AACATCGACT TTAGTGATAA AGCAAGTAGT 
ACTCCATATT CACTATCTGC TGATGGGTCA CCTTCCTCTC TTGGGTCAAG CTGTGATCAT 
CGTCAGTCTC CGTTATCTGA TTACATGAGT GTGGATATTG ATGTACAGTC TCCAAAAGCA 
ACGGCAGAAC AGTCTAACTC TTTAACAGAC ATTTCATTAT ATGCATGCAC TGTTGTCTCT 
AGAATGCAGC CAAATGCTGA ATATGCCAAG CTTCCCTGTG GTACAGCTTG TGTCAGCAAA 
ACGGACAACA TAATGGATGA TTACACCACA ATGACTTTTA ACATGGCAAT GACTCCACCA 
AGATCCTTTG CCAGTGAAAC AGAGAATGGT ACAAAAGTGG ACAGTCCTTC ATCCATTGTG 
AATCGGTTGT GTATAGGGGA ATTGACTTCT CTTAACAGTG GCTTTTCTTT ACCAAATCCT 
TTGCCTGAAC CTATAGCTGG GCCTAAAGTT ATCCGTGCAG ACTCACAGGG AAGGCGAAGG 
CACAGTTCTG AAACTTTTGC CTCTTCCAGC ACGGTGACCA CTTCCTCTTC TTGCTTTACT 
GAAAGTGGCA AGAGGCACAG CTCAGCCTCA TTTGACAATG TATGGCTTAA ACCTGATGAA 
AACAGTTGTG AACAAGAGAA TAAAATGTCC AGGCATTGCT CAACAGGATT TCAGAATGGG 
TTAAACTACA TCTCTTTGAG TATGCACAAT GGTGTTTGTG AACCAACGTC CCCAGATTGC 
CATCAGCACC AAAACGGAAG TAGAAATCTG GAGAGTGGGG GTTATGTCAG CATCGACTTC 
ACAAGGTGTG ACTGTCTGAA GTGTCCCACT TCAAGAAAAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P

A novel insulin receptor substrate protein, xIRS-u, potentiates insulin signaling: functional importance of its pleckstrin homology domain.
Molecular endocrinology (Baltimore, Md.)12(8)1086-98(1998 Aug)
Ohan N,Bayaa M,Kumar P,Zhu L,Liu XJ

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

irs4.S cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM