AZIN1 cDNA ORF clone, Taeniopygia guttata(zebra finch)

Gene
Clones
gRNAs

Summary

Gene Symbol	AZIN1
Entrez Gene ID	100222035
Full Name	antizyme inhibitor 1
Gene Type	protein-coding
Organism	Taeniopygia guttata(zebra finch)
Summary	The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine; however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 1, the first member of this gene family that is ubiquitously expressed, and is localized in the nucleus and cytoplasm. Overexpression of antizyme inhibitor 1 gene has been associated with increased proliferation, cellular transformation and tumorigenesis. Gene knockout studies showed that homozygous mutant mice lacking functional antizyme inhibitor 1 gene died at birth with abnormal liver morphology. [provided by RefSeq, Sep 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_030264013.1	XP_030119873.1	antizyme inhibitor 1 isoform X1
NM_001291450.1	NP_001278379.1	antizyme inhibitor 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor.
Kahana C
Essays in biochemistry4647-61(2009 Nov)

The Songbird Neurogenomics (SoNG) Initiative: community-based tools and strategies for study of brain gene function and evolution.
Replogle K, Arnold AP, Ball GF, Band M, Bensch S, Brenowitz EA, Dong S, Drnevich J, Ferris M, George JM, Gong G, Hasselquist D, Hernandez AG, Kim R, Lewin HA, Liu L, Lovell PV, Mello CV, Naurin S, Rodriguez-Zas S, Thimmapuram J, Wade J, Clayton DF
BMC genomics9131(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AZIN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AZIN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OTd00028	NM_001291450.1 Latest version!	Taeniopygia guttata antizyme inhibitor 1 (AZIN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OTd34062	XM_030264013.1 Latest version!	Taeniopygia guttata antizyme inhibitor 1 (AZIN1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AZIN1 ( NM_001291450.1 ) cDNA ORF clone, Taeniopygia guttata(zebra finch) -> NP_001278379.1 Taeniopygia guttata antizyme inhibitor 1 (AZIN1), mRNA.

Price & Availability↑

CloneID	OTd00028
Clone ID Related Accession (Same CDS sequence)	NM_001291450.1
Accession Version	NM_001291450.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548345600000
Organism	Taeniopygia guttata(zebra finch)
Product	antizyme inhibitor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from ABQF01005914.1, FE713503.1 and FE715896.1. On Apr 16, 2014 this sequence version replaced XM_002200286.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02689728, SAMN02689729 [ECO:0000348] ##Evidence-Data-END##

ATGAAAGGAT TTCTTGAGGA TGCAAATTAC TCCATTGGTC TGTTGGATGA AGGAGCAACT 
CTTGCAGATG TTATTGACAA CTGTATTTAT GAACATACTC ATACTGGAAA AAAGGCATTT 
TATGTTGGAG ATCTTGGAAA GCTTGTAAGG AATAACGTGC AATGGCAGAA TGTGATGGCA 
CCAATAAAGC CATTTTATCC TGTAAAATGC AATTCTACTC CAGGTGTACT CGAAATTCTG 
GGAACCCTTG GTGTTGGTTT TGCATGTTCC AGTAAAGCTG AAATGGCTTT GGTACAAGAC 
CTGGGCATTT CTCCTGAAAA CATCATTTAC ACAAATCCTT GCAAGCAAGC CTCTCAGATC 
AAGTATGCAG CAAAAGCTGG GATAAACATC ATGACTTGTG ACAATGATAT TGAGCTGAAG 
AAAATTTCAC GTAACCATCC AAATGCCAAG CTCTTACTGC ACATTGCCAC AGAAGACATT 
ACTGCTGGTG AGGAGATGAA TATGAAGTTT GGCACCACCC TGAAGAACTG TAGGCACCTT 
ATGGAATGTG CTAAGGAGCT GGGAGTCCAA ATAGTTGGTG TCAAATTTCA TGTTTCAGGC 
TCTTGCAAGG ATCTGCAAAC ATACATTCAT GCTCTATCTG ATGCTCGGTG TGTGTTTGAT 
ATGGCTGAAG AATTTGGCTT TAAGATGAAC ATGTTGGATA TTGGTGGGGG CTTCACAGGT 
TCAGAACTTC AGCTGGAAGA GGTTAATCAT GTCATCAGGC CATTGCTGGA TGTCTACTTT 
CCTAAGGAAT CTGGTATTAA TGTGATTGCA GAGCCTGGAT GTTATTATGT TTCATCCGCA 
TTTACACTGG CAGTGAACGT CATTGCAAAG AAGACTGTTG AGTATGATAA ATTTCTTCCT 
TCTGGAGTGG AGCAAACCAG GAATGATGAT GAACCAGTTT TTACATATTA CATAAATGAT 
GGTGTTTATG GTTCTTTTGC AAGTAAATTG TCTGAGAAAC TGAATACTAT CCCAGAGGTT 
CACAAGAAAT ACAAGGAAGA TGAGCCTCTG TTTGCGAGCA GCCTTTGGGG TCCATCCTGT 
GATGAGCTTG ATCAAATTGT GGAAAACTGT CTTCTTCCCG AGTTGAGCGT TGGAGATTGG 
CTGATCTTTG ACAATATGGG TTCTGGTACC TTAGGTGAAC AGTCTACCTT TAACGACTAT 
CAGAGGCCAC TGATTTACTA CATGATGTCT TTCAGTGACT GGGATGAGAT GCAAGATGCT 
GGAATTGCTT CAGACACATT GATGAAGAAT TTCTTCTTTG TGCCTTCATG CATTCAGCTG 
AGCCCGGAAG AACGCTTTTC CACTGCAGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278379.1
CDS	255..1607
Translation	MKGFLEDANYSIGLLDEGATLADVIDNCIYEHTHTGKKAFYVGDLGKLVRNNVQWQNVMAPIKPFYPVKCNSTPGVLEILGTLGVGFACSSKAEMALVQDLGISPENIIYTNPCKQASQIKYAAKAGINIMTCDNDIELKKISRNHPNAKLLLHIATEDITAGEEMNMKFGTTLKNCRHLMECAKELGVQIVGVKFHVSGSCKDLQTYIHALSDARCVFDMAEEFGFKMNMLDIGGGFTGSELQLEEVNHVIRPLLDVYFPKESGINVIAEPGCYYVSSAFTLAVNVIAKKTVEYDKFLPSGVEQTRNDDEPVFTYYINDGVYGSFASKLSEKLNTIPEVHKKYKEDEPLFASSLWGPSCDELDQIVENCLLPELSVGDWLIFDNMGSGTLGEQSTFNDYQRPLIYYMMSFSDWDEMQDAGIASDTLMKNFFFVPSCIQLSPEERFSTAA

Target ORF information:

RefSeq Version	NM_001291450.1
Organism	Taeniopygia guttata(zebra finch)
Definition	Taeniopygia guttata antizyme inhibitor 1 (AZIN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291450.1

ORF Insert Sequence:

ATGAAAGGAT TTCTTGAGGA TGCAAATTAC TCCATTGGTC TGTTGGATGA AGGAGCAACT 
CTTGCAGATG TTATTGACAA CTGTATTTAT GAACATACTC ATACTGGAAA AAAGGCATTT 
TATGTTGGAG ATCTTGGAAA GCTTGTAAGG AATAACGTGC AATGGCAGAA TGTGATGGCA 
CCAATAAAGC CATTTTATCC TGTAAAATGC AATTCTACTC CAGGTGTACT CGAAATTCTG 
GGAACCCTTG GTGTTGGTTT TGCATGTTCC AGTAAAGCTG AAATGGCTTT GGTACAAGAC 
CTGGGCATTT CTCCTGAAAA CATCATTTAC ACAAATCCTT GCAAGCAAGC CTCTCAGATC 
AAGTATGCAG CAAAAGCTGG GATAAACATC ATGACTTGTG ACAATGATAT TGAGCTGAAG 
AAAATTTCAC GTAACCATCC AAATGCCAAG CTCTTACTGC ACATTGCCAC AGAAGACATT 
ACTGCTGGTG AGGAGATGAA TATGAAGTTT GGCACCACCC TGAAGAACTG TAGGCACCTT 
ATGGAATGTG CTAAGGAGCT GGGAGTCCAA ATAGTTGGTG TCAAATTTCA TGTTTCAGGC 
TCTTGCAAGG ATCTGCAAAC ATACATTCAT GCTCTATCTG ATGCTCGGTG TGTGTTTGAT 
ATGGCTGAAG AATTTGGCTT TAAGATGAAC ATGTTGGATA TTGGTGGGGG CTTCACAGGT 
TCAGAACTTC AGCTGGAAGA GGTTAATCAT GTCATCAGGC CATTGCTGGA TGTCTACTTT 
CCTAAGGAAT CTGGTATTAA TGTGATTGCA GAGCCTGGAT GTTATTATGT TTCATCCGCA 
TTTACACTGG CAGTGAACGT CATTGCAAAG AAGACTGTTG AGTATGATAA ATTTCTTCCT 
TCTGGAGTGG AGCAAACCAG GAATGATGAT GAACCAGTTT TTACATATTA CATAAATGAT 
GGTGTTTATG GTTCTTTTGC AAGTAAATTG TCTGAGAAAC TGAATACTAT CCCAGAGGTT 
CACAAGAAAT ACAAGGAAGA TGAGCCTCTG TTTGCGAGCA GCCTTTGGGG TCCATCCTGT 
GATGAGCTTG ATCAAATTGT GGAAAACTGT CTTCTTCCCG AGTTGAGCGT TGGAGATTGG 
CTGATCTTTG ACAATATGGG TTCTGGTACC TTAGGTGAAC AGTCTACCTT TAACGACTAT 
CAGAGGCCAC TGATTTACTA CATGATGTCT TTCAGTGACT GGGATGAGAT GCAAGATGCT 
GGAATTGCTT CAGACACATT GATGAAGAAT TTCTTCTTTG TGCCTTCATG CATTCAGCTG 
AGCCCGGAAG AACGCTTTTC CACTGCAGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AZIN1 ( XM_030264013.1 ) cDNA ORF clone, Taeniopygia guttata(zebra finch) -> XP_030119873.1 Taeniopygia guttata antizyme inhibitor 1 (AZIN1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OTd34062
Clone ID Related Accession (Same CDS sequence)	XM_030264013.1
Accession Version	XM_030264013.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565193600000
Organism	Taeniopygia guttata(zebra finch)
Product	antizyme inhibitor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_044213.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Taeniopygia guttata Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGGAT TTCTTGAGGA TGCAAATTAC TCCATTGGTC TGTTGGATGA AGGAGCAACT 
CTTGCAGATG TTATTGACAA CTGTATTTAT GAACATACTC ATACTGGAAA AAAGGCATTT 
TATGTTGGAG ATCTTGGAAA GCTTGTAAGG AATAACGTGC AATGGCAGAA TGTGATGGCA 
CCAATAAAGC CATTTTATCC TGTAAAATGC AATTCTACTC CAGGTGTACT CGAAATTCTG 
GGAACCCTTG GTGTTGGTTT TGCATGTTCC AGTAAAGCTG AAATGGCTTT GGTACAAGAC 
CTGGGCATTT CTCCTGAAAA CATCATATAC ACAAATCCTT GCAAGCAAGC CTCTCAGATC 
AAGTATGCAG CAAAAGCTGG GATAAACATC ATGACTTGTG ACAATGATAT TGAGCTGAAG 
AAAATTTCAC GTAACCATCC AAATGCCAAG CTCTTACTGC ACATTGCCAC AGAAGACATT 
ACTGCTGGTG AGGAGATGAA TATGAAGTTT GGCACCACCC TGAAGAACTG TAGGCACCTT 
ATGGAATGTG CTAAGGAGCT GGGAGTCCAA ATAGTTGGTG TCAAATTTCA TGTTTCAGGC 
TCTTGCAAGG ATCTGCAAAC ATACATTCAT GCTCTATCTG ATGCTCGGTG TGTGTTTGAT 
ATGGCTGAAG AATTTGGCTT TAAGATGAAC ATGTTGGATA TTGGTGGGGG CTTCACAGGT 
TCAGAACTTC AGCTGGAAGA GGTTAATCAT GTCATCAGGC CATTGCTGGA TGTCTACTTT 
CCTAAGGAAT CTGGTATTAA TGTGATTGCA GAGCCTGGAT GTTATTATGT TTCATCCGCA 
TTTACACTGG CAGTGAACGT CATTGCAAAG AAGACTGTTG AGTATGATAA ATTTCTTCCT 
TCTGGAGTGG AGCAAACCAG GAATGATGAT GAACCAGTTT TTACATATTA CATAAATGAT 
GGTGTTTATG GTTCTTTTGC AAGTAAATTG TCTGAGAAAC TGAATACTAT CCCAGAGGTT 
CACAAGAAAT ACAAGGAAGA TGAGCCTCTG TTTGCGAGCA GCCTTTGGGG TCCATCCTGT 
GATGAGCTTG ATCAAATTGT GGAAAACTGT CTTCTTCCCG AGTTGAGCGT TGGAGATTGG 
CTGATCTTTG ACAATATGGG TTCTGGTACC TTAGGTGAAC AGTCTACCTT TAACGACTAT 
CAGAGGCCAC TGATTTACTA CATGATGTCT TTCAGTGACT GGGATGAGAT GCAAGATGCT 
GGAATTGCTT CAGACACATT GATGAAGAAC TTCTTCTTTG TGCCTTCATG CATTCAGCTG 
AGCCCGGAAG AACGCTTTTC CACTGCAGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030119873.1
CDS	585..1937
Translation	MKGFLEDANYSIGLLDEGATLADVIDNCIYEHTHTGKKAFYVGDLGKLVRNNVQWQNVMAPIKPFYPVKCNSTPGVLEILGTLGVGFACSSKAEMALVQDLGISPENIIYTNPCKQASQIKYAAKAGINIMTCDNDIELKKISRNHPNAKLLLHIATEDITAGEEMNMKFGTTLKNCRHLMECAKELGVQIVGVKFHVSGSCKDLQTYIHALSDARCVFDMAEEFGFKMNMLDIGGGFTGSELQLEEVNHVIRPLLDVYFPKESGINVIAEPGCYYVSSAFTLAVNVIAKKTVEYDKFLPSGVEQTRNDDEPVFTYYINDGVYGSFASKLSEKLNTIPEVHKKYKEDEPLFASSLWGPSCDELDQIVENCLLPELSVGDWLIFDNMGSGTLGEQSTFNDYQRPLIYYMMSFSDWDEMQDAGIASDTLMKNFFFVPSCIQLSPEERFSTAA

Target ORF information:

RefSeq Version	XM_030264013.1
Organism	Taeniopygia guttata(zebra finch)
Definition	Taeniopygia guttata antizyme inhibitor 1 (AZIN1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030264013.1

ORF Insert Sequence:

ATGAAAGGAT TTCTTGAGGA TGCAAATTAC TCCATTGGTC TGTTGGATGA AGGAGCAACT 
CTTGCAGATG TTATTGACAA CTGTATTTAT GAACATACTC ATACTGGAAA AAAGGCATTT 
TATGTTGGAG ATCTTGGAAA GCTTGTAAGG AATAACGTGC AATGGCAGAA TGTGATGGCA 
CCAATAAAGC CATTTTATCC TGTAAAATGC AATTCTACTC CAGGTGTACT CGAAATTCTG 
GGAACCCTTG GTGTTGGTTT TGCATGTTCC AGTAAAGCTG AAATGGCTTT GGTACAAGAC 
CTGGGCATTT CTCCTGAAAA CATCATATAC ACAAATCCTT GCAAGCAAGC CTCTCAGATC 
AAGTATGCAG CAAAAGCTGG GATAAACATC ATGACTTGTG ACAATGATAT TGAGCTGAAG 
AAAATTTCAC GTAACCATCC AAATGCCAAG CTCTTACTGC ACATTGCCAC AGAAGACATT 
ACTGCTGGTG AGGAGATGAA TATGAAGTTT GGCACCACCC TGAAGAACTG TAGGCACCTT 
ATGGAATGTG CTAAGGAGCT GGGAGTCCAA ATAGTTGGTG TCAAATTTCA TGTTTCAGGC 
TCTTGCAAGG ATCTGCAAAC ATACATTCAT GCTCTATCTG ATGCTCGGTG TGTGTTTGAT 
ATGGCTGAAG AATTTGGCTT TAAGATGAAC ATGTTGGATA TTGGTGGGGG CTTCACAGGT 
TCAGAACTTC AGCTGGAAGA GGTTAATCAT GTCATCAGGC CATTGCTGGA TGTCTACTTT 
CCTAAGGAAT CTGGTATTAA TGTGATTGCA GAGCCTGGAT GTTATTATGT TTCATCCGCA 
TTTACACTGG CAGTGAACGT CATTGCAAAG AAGACTGTTG AGTATGATAA ATTTCTTCCT 
TCTGGAGTGG AGCAAACCAG GAATGATGAT GAACCAGTTT TTACATATTA CATAAATGAT 
GGTGTTTATG GTTCTTTTGC AAGTAAATTG TCTGAGAAAC TGAATACTAT CCCAGAGGTT 
CACAAGAAAT ACAAGGAAGA TGAGCCTCTG TTTGCGAGCA GCCTTTGGGG TCCATCCTGT 
GATGAGCTTG ATCAAATTGT GGAAAACTGT CTTCTTCCCG AGTTGAGCGT TGGAGATTGG 
CTGATCTTTG ACAATATGGG TTCTGGTACC TTAGGTGAAC AGTCTACCTT TAACGACTAT 
CAGAGGCCAC TGATTTACTA CATGATGTCT TTCAGTGACT GGGATGAGAT GCAAGATGCT 
GGAATTGCTT CAGACACATT GATGAAGAAC TTCTTCTTTG TGCCTTCATG CATTCAGCTG 
AGCCCGGAAG AACGCTTTTC CACTGCAGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor.
Essays in biochemistry4647-61(2009 Nov)
Kahana C

The Songbird Neurogenomics (SoNG) Initiative: community-based tools and strategies for study of brain gene function and evolution.
BMC genomics9131(2008 Mar)
Replogle K,Arnold AP,Ball GF,Band M,Bensch S,Brenowitz EA,Dong S,Drnevich J,Ferris M,George JM,Gong G,Hasselquist D,Hernandez AG,Kim R,Lewin HA,Liu L,Lovell PV,Mello CV,Naurin S,Rodriguez-Zas S,Thimmapuram J,Wade J,Clayton DF

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

AZIN1 cDNA ORF clone, Taeniopygia guttata(zebra finch)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM