Gene Symbol | IRF3 |
Entrez Gene ID | 396656 |
Full Name | interferon regulatory factor 3 |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
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ORF » Species Summary » Sus scrofa » IRF3 cDNA ORF clone
Gene Symbol | IRF3 |
Entrez Gene ID | 396656 |
Full Name | interferon regulatory factor 3 |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
mRNA | Protein | Name |
---|---|---|
NM_213770.1 | NP_998935.1 | interferon regulatory factor 3 |
XM_005664719.2 | XP_005664776.1 | interferon regulatory factor 3 isoform X1 |
XM_005664722.2 | XP_005664779.1 | interferon regulatory factor 3 isoform X2 |
XM_005664720.2 | XP_005664777.1 | interferon regulatory factor 3 isoform X1 |
XM_013998634.1 | XP_013854088.1 | interferon regulatory factor 3 isoform X1 |
Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.
Gottipati K, Holthauzen LM, Ruggli N, Choi KH
Journal of virology90(17)7740-7(2016 09)
The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production.
Mine J, Tamura T, Mitsuhashi K, Okamatsu M, Parchariyanon S, Pinyochon W, Ruggli N, Tratschin JD, Kida H, Sakoda Y
The Journal of general virology96(Pt 7)1746-56(2015 Jul)
Classical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7.
Fiebach AR, Guzylack-Piriou L, Python S, Summerfield A, Ruggli N
Journal of virology85(16)8002-11(2011 Aug)
Porcine reproductive and respiratory syndrome virus (PRRSV) could be sensed by professional beta interferon-producing system and had mechanisms to inhibit this action in MARC-145 cells.
Shi X, Wang L, Zhi Y, Xing G, Zhao D, Deng R, Zhang G
Virus research153(1)151-6(2010 Oct)
Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.
Szymanski MR, Fiebach AR, Tratschin JD, Gut M, Ramanujam VM, Gottipati K, Patel P, Ye M, Ruggli N, Choi KH
Journal of molecular biology391(2)438-49(2009 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following IRF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00254 | |
Clone ID Related Accession (Same CDS sequence) | NM_213770.1 | |
Accession Version | NM_213770.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1577203200000 | |
Organism | Sus scrofa(pig) | |
Product | interferon regulatory factor 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB116563.1. ##Evidence-Data-START## Transcript exon combination :: AB116563.1, EU294308.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1487420, SAMEA1487441 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_998935.1 |
CDS | 1..1260 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe11556 | |
Clone ID Related Accession (Same CDS sequence) | XM_005664719.2 , XM_005664720.2 , XM_013998634.1 | |
Accession Version | XM_005664719.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | interferon regulatory factor 3 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003610433.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005664719.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005664776.1 |
CDS | 280..1539 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe11556 | |
Clone ID Related Accession (Same CDS sequence) | XM_005664719.2 , XM_005664720.2 , XM_013998634.1 | |
Accession Version | XM_005664720.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | interferon regulatory factor 3 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003610433.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005664720.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005664777.1 |
CDS | 455..1714 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe11556 | |
Clone ID Related Accession (Same CDS sequence) | XM_005664719.2 , XM_005664720.2 , XM_013998634.1 | |
Accession Version | XM_013998634.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | interferon regulatory factor 3 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003610433.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013854088.1 |
CDS | 325..1584 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe11558 | |
Clone ID Related Accession (Same CDS sequence) | XM_005664722.2 | |
Accession Version | XM_005664722.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | interferon regulatory factor 3 isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003610433.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005664722.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005664779.1 |
CDS | 280..1158 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGAACTC AGAAGCCTCG GATCCTGCCC TGGCTGATAT CTCAGCTGAA CCAGGGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. |
The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production. |
Classical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7. |
Porcine reproductive and respiratory syndrome virus (PRRSV) could be sensed by professional beta interferon-producing system and had mechanisms to inhibit this action in MARC-145 cells. |
Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation. |