Abcg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcg1
Entrez Gene ID	85264
Full Name	ATP binding cassette subfamily G member 1
Synonyms	Abc8
General protein information	Preferred Names ATP binding cassette subfamily G member 1 Names ATP-binding cassette sub-family G member 1 ATP-binding cassette, sub-family G (WHITE), member 1 ATP-binding cassette, subfamily G (WHITE), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	ATP-binding cassette (ABC) half-transporter that facilitates the efflux of excess cholesterol from macrophages and may play an important role in cholesterol homeostasis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053502.1	NP_445954.1	ATP-binding cassette sub-family G member 1
XM_006256233.3	XP_006256295.1	ATP-binding cassette sub-family G member 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ABCG1	NP_058198.2
Canis lupus familiaris (dog)	ABCG1	XP_005638985.1
Mus musculus (house mouse)	Abcg1	NP_033723.1
Gallus gallus (chicken)	ABCG1	XP_003640549.1
Xenopus tropicalis (tropical clawed frog)	LOC100496811	XP_002942182.2
Rattus norvegicus (Norway rat)	Abcg1	NP_445954.1
Danio rerio (zebrafish)	abcg1	NP_001103924.1
Arabidopsis thaliana (thale cress)	WBC27	NP_187928.2
Pan troglodytes (chimpanzee)	ABCG1	XP_514918.3
Caenorhabditis elegans (roundworm)	wht-5	NP_502352.1
Oryza sativa (rice)	Os06g0607700	NP_001058033.1
Bos taurus (cattle)	ABCG1	NP_001192457.1

Gene Ontology
Bibliography

Related articles in PubMed

Inhibition of ERK1/2 improves lipid balance in rat macrophages via ABCA1/G1 and CD36.
Xue XH, Shi FF, Chen T, Wei W, Zhou XM, Chen LD
Molecular medicine reports13(2)1533-40(2016 Feb)

ABCG1 is involved in vitamin E efflux.
Olivier M, BottG R, Frisdal E, Nowick M, Plengpanich W, Desmarchelier C, Roi S, Quinn CM, Gelissen I, Jessup W, Van Eck M, Guérin M, Le Goff W, Reboul E
Biochimica et biophysica acta1841(12)1741-51(2014 Dec)

N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1.
Machado JT, Iborra RT, Fusco FB, Castilho G, Pinto RS, Machado-Lima A, Nakandakare ER, Seguro AC, Shimizu MH, Catanozi S, Passarelli M
Atherosclerosis237(1)343-52(2014 Nov)

Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.
Gu HM, Wang FQ, Zhang DW
Biochimica et biophysica acta1841(6)847-58(2014 Jun)

ABCA1 and ABCG1 expression in the small intestine of type 2 diabetic rats.
Lou J, Zhou H, Li C, Hu L, Lu X, Li J, Yao H, Li W, Zhang X, Xu M
Laboratory medicine45(1)17-24(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abcg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13585	NM_053502.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
ORa39324	XM_006256233.3 Latest version!	Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcg1 ( NM_053502.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445954.1 Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), mRNA.

Price & Availability↑

CloneID	ORa13585
Clone ID Related Accession (Same CDS sequence)	NM_053502.1
Accession Version	NM_053502.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2001bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family G member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ303374.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ303374.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTGTC TGATGGCCGC TTTCTCGGTC GGCACCGCCA TGAATGCCAG CAACTACTCG 
GCCGCAATGA CGGAACCCAA GTCCGTGTGC GTGTCGGTGG ACGAGGTCGT GTCCAGCAAC 
GTGGATGAGC TTGAGACAGA TCTGCTTAAT GGGCACCTGA AGAAGGTGGA CAACAACTTC 
ACGGAGGCCC AGCGCTTTTC CTCCCTGCCG CGGAGGGCGG CCGTGAATAT CGAATTCAAG 
GACCTTTCTT ACTCCGTACC CGAGGGACCC TGGTGGAGGA AGAAAGGATA CAAGACCCTT 
TTGAAAGGGA TCTCTGGGAA GTTCAACAGT GGAGAGCTGG TGGCCATCAT GGGTCCTTCT 
GGAGCTGGGA AGTCCACACT CATGAATATT CTGGCGGGAT ACAGGGAGAC GGGCATGAAG 
GGGGCAGTCC TTATCAATGG TATGCCCCGC GACCTGCGCT GCTTCCGGAA GGTCTCGTGC 
TACATCATGC AGGATGACAT GCTGCTGCCT CACCTCACTG TCCAGGAGGC CATGATGGTG 
TCCGCGCATC TGAAGCTGCA AGAGAGGGAT GAAGGCAGAC GGGAGATGGT CAAGGAGATC 
CTGACAGCAC TGGGCTTGCT GCCCTGTGCC AACACACGCA CAGGGAGCCT CTCGGGTGGC 
CAGCGGAAGC GCCTGGCCAT TGCACTAGAA CTGGTCAACA ACCCTCCTGT TATGTTCTTT 
GATGAGCCCA CCAGTGGCCT GGACAGTGCC TCTTGCTTCC AAGTGGTGTC CCTGATGAAA 
GGGCTGGCCC AGGGCGGCCG CTCCATCGTC TGCACCATCC ACCAACCCAG TGCCAAGCTC 
TTCGAGCTCT TTGACCAGCT TTATGTCCTA AGTCAAGGAC AATGTGTCTA CCGGGGAAAG 
GTCTCGAATC TCGTGCCGTA CCTGAGGGAT CTGGGTCTGA ACTGCCCTAC CTACCACAAC 
CCTGCAGACT TTGTCATGGA AGTGGCATCA GGGGAGTACG GTGATCAGAA CAGCCGCCTG 
GTGAGGGCCG TTCGGGAGGG CATGTGTGAC TCTGACTATA AGAGAGAACT CGGGGGCGAC 
GGAGACGTGA ACCCGTTCCT CTGGCACCGG CCTGCTGAAG AGGACTCGGC CTCCATGGAA 
GGTTGCCACA GCTTCTCGGC CAGCTGCCTC ACCCAGTTCT GCATCCTCTT CAAGAGGACC 
TTCCTTAGCA TCATGCGGGA CTCGGTACTG ACACACCTGC GAATCACCTC ACACATCGGG 
ATCGGTCTCC TCATTGGCCT CCTGTACCTT GGGATTGGGA ACGAAGCCAA GAAGGTCCTG 
AGCAACTCCG GCTTCCTGTT CTTCTCCATG CTGTTCCTCA TGTTCGCCGC CCTCATGCCC 
ACCGTTCTGA CCTTTCCCCT CGAGATGAGT GTCTTCCTCC GAGAGCACCT GAACTACTGG 
TACAGTCTGA AGGCCTACTA CCTGGCCAAG ACCATGGCTG ATGTCCCCTT TCAGATCATG 
TTCCCCGTGG CCTACTGCAG CATCGTGTAC TGGATGACAT CACAGCCGTC GGACGCTGTG 
CGTTTTGTGC TGTTCGCTGC ACTGGGCACC ATGACCTCGT TGGTGGCCCA GTCCTTAGGC 
CTACTCATTG GAGCTGCGTC CACATCCCTG CAGGTTGCGA CGTTTGTGGG TCCCGTGACA 
GCCATCCCTG TCTTGCTCTT CTCCGGGTTC TTTGTCAGCT TTGACACCAT CCCAACCTAC 
CTGCAGTGGA TGTCCTACAT CTCCTACGTC AGATACGGCT TCGAGGGGGT CATCCTGTCC 
ATCTATGGCT TGGACCGAGA GGACCTGCAC TGCGACATCG CGGAGACATG CCACTTCCAG 
AAGTCAGAGG CCATCCTGCG GGAGCTAGAT GTGGAGAACG CGAAGCTATA CCTGGATTTC 
ATCGTCCTGG GCATCTTCTT CATCTCCCTG CGGCTCATCG CCTATTTTGT CCTGAGATAC 
AAAATCCGGG CTGAGAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445954.1
CDS	78..2078
Translation	MACLMAAFSVGTAMNASNYSAAMTEPKSVCVSVDEVVSSNVDELETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQERDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDYKRELGGDGDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER

Target ORF information:

RefSeq Version	NM_053502.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053502.1

ORF Insert Sequence:

ATGGCCTGTC TGATGGCCGC TTTCTCGGTC GGCACCGCCA TGAATGCCAG CAACTACTCG 
GCCGCAATGA CGGAACCCAA GTCCGTGTGC GTGTCGGTGG ACGAGGTCGT GTCCAGCAAC 
GTGGATGAGC TTGAGACAGA TCTGCTTAAT GGGCACCTGA AGAAGGTGGA CAACAACTTC 
ACGGAGGCCC AGCGCTTTTC CTCCCTGCCG CGGAGGGCGG CCGTGAATAT CGAATTCAAG 
GACCTTTCTT ACTCCGTACC CGAGGGACCC TGGTGGAGGA AGAAAGGATA CAAGACCCTT 
TTGAAAGGGA TCTCTGGGAA GTTCAACAGT GGAGAGCTGG TGGCCATCAT GGGTCCTTCT 
GGAGCTGGGA AGTCCACACT CATGAATATT CTGGCGGGAT ACAGGGAGAC GGGCATGAAG 
GGGGCAGTCC TTATCAATGG TATGCCCCGC GACCTGCGCT GCTTCCGGAA GGTCTCGTGC 
TACATCATGC AGGATGACAT GCTGCTGCCT CACCTCACTG TCCAGGAGGC CATGATGGTG 
TCCGCGCATC TGAAGCTGCA AGAGAGGGAT GAAGGCAGAC GGGAGATGGT CAAGGAGATC 
CTGACAGCAC TGGGCTTGCT GCCCTGTGCC AACACACGCA CAGGGAGCCT CTCGGGTGGC 
CAGCGGAAGC GCCTGGCCAT TGCACTAGAA CTGGTCAACA ACCCTCCTGT TATGTTCTTT 
GATGAGCCCA CCAGTGGCCT GGACAGTGCC TCTTGCTTCC AAGTGGTGTC CCTGATGAAA 
GGGCTGGCCC AGGGCGGCCG CTCCATCGTC TGCACCATCC ACCAACCCAG TGCCAAGCTC 
TTCGAGCTCT TTGACCAGCT TTATGTCCTA AGTCAAGGAC AATGTGTCTA CCGGGGAAAG 
GTCTCGAATC TCGTGCCGTA CCTGAGGGAT CTGGGTCTGA ACTGCCCTAC CTACCACAAC 
CCTGCAGACT TTGTCATGGA AGTGGCATCA GGGGAGTACG GTGATCAGAA CAGCCGCCTG 
GTGAGGGCCG TTCGGGAGGG CATGTGTGAC TCTGACTATA AGAGAGAACT CGGGGGCGAC 
GGAGACGTGA ACCCGTTCCT CTGGCACCGG CCTGCTGAAG AGGACTCGGC CTCCATGGAA 
GGTTGCCACA GCTTCTCGGC CAGCTGCCTC ACCCAGTTCT GCATCCTCTT CAAGAGGACC 
TTCCTTAGCA TCATGCGGGA CTCGGTACTG ACACACCTGC GAATCACCTC ACACATCGGG 
ATCGGTCTCC TCATTGGCCT CCTGTACCTT GGGATTGGGA ACGAAGCCAA GAAGGTCCTG 
AGCAACTCCG GCTTCCTGTT CTTCTCCATG CTGTTCCTCA TGTTCGCCGC CCTCATGCCC 
ACCGTTCTGA CCTTTCCCCT CGAGATGAGT GTCTTCCTCC GAGAGCACCT GAACTACTGG 
TACAGTCTGA AGGCCTACTA CCTGGCCAAG ACCATGGCTG ATGTCCCCTT TCAGATCATG 
TTCCCCGTGG CCTACTGCAG CATCGTGTAC TGGATGACAT CACAGCCGTC GGACGCTGTG 
CGTTTTGTGC TGTTCGCTGC ACTGGGCACC ATGACCTCGT TGGTGGCCCA GTCCTTAGGC 
CTACTCATTG GAGCTGCGTC CACATCCCTG CAGGTTGCGA CGTTTGTGGG TCCCGTGACA 
GCCATCCCTG TCTTGCTCTT CTCCGGGTTC TTTGTCAGCT TTGACACCAT CCCAACCTAC 
CTGCAGTGGA TGTCCTACAT CTCCTACGTC AGATACGGCT TCGAGGGGGT CATCCTGTCC 
ATCTATGGCT TGGACCGAGA GGACCTGCAC TGCGACATCG CGGAGACATG CCACTTCCAG 
AAGTCAGAGG CCATCCTGCG GGAGCTAGAT GTGGAGAACG CGAAGCTATA CCTGGATTTC 
ATCGTCCTGG GCATCTTCTT CATCTCCCTG CGGCTCATCG CCTATTTTGT CCTGAGATAC 
AAAATCCGGG CTGAGAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcg1 ( XM_006256233.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256295.1 Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa39324
Clone ID Related Accession (Same CDS sequence)	XM_006256233.3
Accession Version	XM_006256233.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family G member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256233.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAAC CCAAGTCCGT GTGCGTGTCG GTGGACGAGG TCGTGTCCAG CAACGTGGAT 
GAGCTTGAGA CAGATCTGCT TAATGGGCAC CTGAAGAAGG TGGACAACAA CTTCACGGAG 
GCCCAGCGCT TTTCCTCCCT GCCGCGGAGG GCAGCCGTGA ATATCGAATT CAAGGACCTT 
TCTTACTCCG TACCCGAGGG ACCCTGGTGG AGGAAGAAAG GATACAAGAC CCTTTTGAAA 
GGGATCTCTG GGAAGTTCAA CAGTGGAGAG CTGGTGGCCA TCATGGGTCC TTCTGGAGCT 
GGGAAGTCCA CACTCATGAA TATTCTGGCG GGATACAGGG AGACGGGCAT GAAGGGGGCA 
GTCCTTATCA ATGGTATGCC CCGCGACCTG CGCTGCTTCC GGAAGGTCTC GTGCTACATC 
ATGCAGGATG ACATGCTGCT GCCTCACCTC ACTGTCCAGG AGGCCATGAT GGTGTCCGCG 
CATCTGAAGC TGCAAGAGAA GGATGAAGGC AGACGGGAGA TGGTCAAGGA GATCCTGACA 
GCACTGGGCT TGCTGCCCTG TGCCAACACA CGCACAGGGA GCCTCTCGGG TGGCCAGCGG 
AAGCGCCTGG CCATTGCACT AGAACTGGTC AACAACCCTC CTGTTATGTT CTTTGATGAG 
CCCACCAGTG GCCTGGACAG TGCCTCTTGC TTCCAAGTGG TGTCCCTGAT GAAAGGGCTG 
GCCCAGGGCG GCCGCTCCAT CGTCTGCACC ATCCACCAAC CCAGTGCCAA GCTCTTCGAG 
CTCTTTGACC AGCTTTATGT CCTAAGTCAA GGACAATGTG TCTACCGGGG AAAGGTCTCG 
AATCTCGTGC CGTACCTGAG GGATCTGGGT CTGAACTGCC CTACCTACCA CAACCCTGCA 
GACTTTGTCA TGGAAGTGGC ATCAGGGGAG TACGGTGATC AGAACAGCCG CCTGGTGAGG 
GCCGTTCGGG AGGGCATGTG TGACTCTGAC TATAAGAGAG AACTCGGGGG CGACGGAGAC 
GTGAACCCGT TCCTCTGGCA CCGGCCTGCT GAAGAGGACT CGGCCTCCAT GGAAGGTTGC 
CACAGCTTCT CGGCCAGCTG CCTCACCCAG TTCTGCATCC TCTTCAAGAG GACCTTCCTT 
AGCATCATGC GGGACTCGGT ACTGACACAC CTGCGAATCA CCTCACACAT CGGGATCGGT 
CTCCTCATTG GCCTCCTGTA CCTTGGGATT GGGAACGAAG CCAAGAAGGT CCTGAGCAAC 
TCCGGCTTCC TGTTCTTCTC CATGCTGTTC CTCATGTTCG CCGCCCTCAT GCCCACCGTT 
CTGACCTTTC CCCTCGAGAT GAGTGTCTTC CTCCGAGAGC ACCTGAACTA CTGGTACAGT 
CTGAAGGCCT ACTACCTGGC CAAGACCATG GCTGATGTCC CCTTTCAGAT CATGTTTCCC 
GTGGCCTACT GCAGCATCGT GTACTGGATG ACATCACAGC CGTCGGACGC TGTGCGTTTT 
GTGCTGTTCG CTGCACTGGG CACCATGACC TCGTTGGTGG CCCAGTCCTT AGGCCTACTC 
ATTGGAGCTG CGTCCACATC CCTGCAGGTT GCGACGTTTG TGGGTCCCGT GACAGCCATC 
CCTGTCTTGC TCTTCTCCGG GTTCTTTGTC AGCTTTGACA CCATCCCAAC CTACCTGCAG 
TGGATGTCCT ACATCTCCTA CGTCAGATAC GGCTTCGAGG GGGTCATCCT GTCCATCTAT 
GGCTTGGACC GAGAGGACCT GCACTGCGAC ATCGCGGAGA CATGCCACTT CCAGAAGTCA 
GAGGCCATCC TGCGGGAGCT AGATGTGGAG AACGCGAAGC TATACCTGGA TTTCATCGTC 
CTGGGCATCT TCTTCATCTC CCTGCGGCTC ATCGCCTATT TTGTCCTGAG ATACAAAATC 
CGGGCTGAGA GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256295.1
CDS	260..2194
Translation	MTEPKSVCVSVDEVVSSNVDELETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDYKRELGGDGDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER

Target ORF information:

RefSeq Version	XM_006256233.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily G member 1 (Abcg1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256233.3

ORF Insert Sequence:

ATGACGGAAC CCAAGTCCGT GTGCGTGTCG GTGGACGAGG TCGTGTCCAG CAACGTGGAT 
GAGCTTGAGA CAGATCTGCT TAATGGGCAC CTGAAGAAGG TGGACAACAA CTTCACGGAG 
GCCCAGCGCT TTTCCTCCCT GCCGCGGAGG GCAGCCGTGA ATATCGAATT CAAGGACCTT 
TCTTACTCCG TACCCGAGGG ACCCTGGTGG AGGAAGAAAG GATACAAGAC CCTTTTGAAA 
GGGATCTCTG GGAAGTTCAA CAGTGGAGAG CTGGTGGCCA TCATGGGTCC TTCTGGAGCT 
GGGAAGTCCA CACTCATGAA TATTCTGGCG GGATACAGGG AGACGGGCAT GAAGGGGGCA 
GTCCTTATCA ATGGTATGCC CCGCGACCTG CGCTGCTTCC GGAAGGTCTC GTGCTACATC 
ATGCAGGATG ACATGCTGCT GCCTCACCTC ACTGTCCAGG AGGCCATGAT GGTGTCCGCG 
CATCTGAAGC TGCAAGAGAA GGATGAAGGC AGACGGGAGA TGGTCAAGGA GATCCTGACA 
GCACTGGGCT TGCTGCCCTG TGCCAACACA CGCACAGGGA GCCTCTCGGG TGGCCAGCGG 
AAGCGCCTGG CCATTGCACT AGAACTGGTC AACAACCCTC CTGTTATGTT CTTTGATGAG 
CCCACCAGTG GCCTGGACAG TGCCTCTTGC TTCCAAGTGG TGTCCCTGAT GAAAGGGCTG 
GCCCAGGGCG GCCGCTCCAT CGTCTGCACC ATCCACCAAC CCAGTGCCAA GCTCTTCGAG 
CTCTTTGACC AGCTTTATGT CCTAAGTCAA GGACAATGTG TCTACCGGGG AAAGGTCTCG 
AATCTCGTGC CGTACCTGAG GGATCTGGGT CTGAACTGCC CTACCTACCA CAACCCTGCA 
GACTTTGTCA TGGAAGTGGC ATCAGGGGAG TACGGTGATC AGAACAGCCG CCTGGTGAGG 
GCCGTTCGGG AGGGCATGTG TGACTCTGAC TATAAGAGAG AACTCGGGGG CGACGGAGAC 
GTGAACCCGT TCCTCTGGCA CCGGCCTGCT GAAGAGGACT CGGCCTCCAT GGAAGGTTGC 
CACAGCTTCT CGGCCAGCTG CCTCACCCAG TTCTGCATCC TCTTCAAGAG GACCTTCCTT 
AGCATCATGC GGGACTCGGT ACTGACACAC CTGCGAATCA CCTCACACAT CGGGATCGGT 
CTCCTCATTG GCCTCCTGTA CCTTGGGATT GGGAACGAAG CCAAGAAGGT CCTGAGCAAC 
TCCGGCTTCC TGTTCTTCTC CATGCTGTTC CTCATGTTCG CCGCCCTCAT GCCCACCGTT 
CTGACCTTTC CCCTCGAGAT GAGTGTCTTC CTCCGAGAGC ACCTGAACTA CTGGTACAGT 
CTGAAGGCCT ACTACCTGGC CAAGACCATG GCTGATGTCC CCTTTCAGAT CATGTTTCCC 
GTGGCCTACT GCAGCATCGT GTACTGGATG ACATCACAGC CGTCGGACGC TGTGCGTTTT 
GTGCTGTTCG CTGCACTGGG CACCATGACC TCGTTGGTGG CCCAGTCCTT AGGCCTACTC 
ATTGGAGCTG CGTCCACATC CCTGCAGGTT GCGACGTTTG TGGGTCCCGT GACAGCCATC 
CCTGTCTTGC TCTTCTCCGG GTTCTTTGTC AGCTTTGACA CCATCCCAAC CTACCTGCAG 
TGGATGTCCT ACATCTCCTA CGTCAGATAC GGCTTCGAGG GGGTCATCCT GTCCATCTAT 
GGCTTGGACC GAGAGGACCT GCACTGCGAC ATCGCGGAGA CATGCCACTT CCAGAAGTCA 
GAGGCCATCC TGCGGGAGCT AGATGTGGAG AACGCGAAGC TATACCTGGA TTTCATCGTC 
CTGGGCATCT TCTTCATCTC CCTGCGGCTC ATCGCCTATT TTGTCCTGAG ATACAAAATC 
CGGGCTGAGA GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inhibition of ERK1/2 improves lipid balance in rat macrophages via ABCA1/G1 and CD36.
Molecular medicine reports13(2)1533-40(2016 Feb)
Xue XH,Shi FF,Chen T,Wei W,Zhou XM,Chen LD

ABCG1 is involved in vitamin E efflux.
Biochimica et biophysica acta1841(12)1741-51(2014 Dec)
Olivier M,BottG R,Frisdal E,Nowick M,Plengpanich W,Desmarchelier C,Roi S,Quinn CM,Gelissen I,Jessup W,Van Eck M,Guérin M,Le Goff W,Reboul E

N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1.
Atherosclerosis237(1)343-52(2014 Nov)
Machado JT,Iborra RT,Fusco FB,Castilho G,Pinto RS,Machado-Lima A,Nakandakare ER,Seguro AC,Shimizu MH,Catanozi S,Passarelli M

Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.
Biochimica et biophysica acta1841(6)847-58(2014 Jun)
Gu HM,Wang FQ,Zhang DW

ABCA1 and ABCG1 expression in the small intestine of type 2 diabetic rats.
Laboratory medicine45(1)17-24(2014)
Lou J,Zhou H,Li C,Hu L,Lu X,Li J,Yao H,Li W,Zhang X,Xu M

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Abcg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

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