Plac8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plac8
Entrez Gene ID	360914
Full Name	placenta-specific 8
General protein information	Preferred Names placenta-specific 8 Names placenta-specific gene 8 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108353.1	NP_001101823.1	placenta-specific gene 8 protein

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Plac8	NP_001101823.1
Gallus gallus (chicken)	PLAC8	NP_001264711.1
Macaca mulatta (Rhesus monkey)	PLAC8	XP_001082142.1
Mus musculus (house mouse)	Plac8	NP_631937.1
Canis lupus familiaris (dog)	LOC100685470	XP_005639191.1
Homo sapiens (human)	PLAC8	NP_057703.1
Pan troglodytes (chimpanzee)	PLAC8	XP_003310360.1

Gene Ontology
Bibliography

Related articles in PubMed

New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats.
Sasaki D, Kotoh J, Watadani R, Matsumoto K
Mammalian genome : official journal of the International Mammalian Genome Society26(11-12)619-29(2015 Dec)

Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.
Jimenez-Preitner M, Berney X, Uldry M, Vitali A, Cinti S, Ledford JG, Thorens B
Cell metabolism14(5)658-70(2011 Nov)

Impaired host defense in mice lacking ONZIN.
Ledford JG, Kovarova M, Koller BH
Journal of immunology (Baltimore, Md. : 1950)178(8)5132-43(2007 Apr)

The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1.
Li Y, Rogulski K, Zhou Q, Sims PJ, Prochownik EV
Molecular and cellular biology26(9)3401-13(2006 May)

Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.
Yanagi Y, Takezawa S, Kato S
Investigative ophthalmology & visual science43(11)3489-94(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Plac8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plac8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07188	NM_001108353.1 Latest version!	Rattus norvegicus placenta associated 8 (Plac8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plac8 ( NM_001108353.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101823.1 Rattus norvegicus placenta associated 8 (Plac8), mRNA.

Price & Availability↑

CloneID	ORa07188
Clone ID Related Accession (Same CDS sequence)	NM_001108353.1
Accession Version	NM_001108353.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1554652800000
Organism	Rattus norvegicus(Norway rat)
Product	placenta-specific gene 8 protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474022.1. On or before Oct 4, 2007 this sequence version replaced XM_341188.3, XM_001067597.1. ##Evidence-Data-START## Transcript exon combination :: FQ221955.1, FQ222141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCAGG CAGCAACAGT TATCGTGACT CAACCTGGAT TTGTTCGTGC TCCCCAAAAT 
TCCAACTGGC AGACCAGCCT GTGTGATTGC TTCAGTGACT GTGGAGTCTG CCTCTGTGGG 
ACCTTTTGCT TCACTTGTCT TGGATGTCAA GTGGCAGCTG ACATGAATGA ATGTTGTTTG 
TGTGGAACAA CGGTGGCGAT GAGGACTCTC TACCGAACCC GATACGGCAT TCCTGGGTCT 
ATTTGTGATG ACTACATGGT CACCCTCTTC TGTCCTGTTT GCTCTGTGTG CCAAATCAAG 
AGAGACATTA ACAGGAGGAG AGCCATGAAC GCTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101823.1
CDS	114..452
Translation	MAQAATVIVTQPGFVRAPQNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQIKRDINRRRAMNAF

Target ORF information:

RefSeq Version	NM_001108353.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus placenta associated 8 (Plac8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108353.1

ORF Insert Sequence:

ATGGCTCAGG CAGCAACAGT TATCGTGACT CAACCTGGAT TTGTTCGTGC TCCCCAAAAT 
TCCAACTGGC AGACCAGCCT GTGTGATTGC TTCAGTGACT GTGGAGTCTG CCTCTGTGGG 
ACCTTTTGCT TCACTTGTCT TGGATGTCAA GTGGCAGCTG ACATGAATGA ATGTTGTTTG 
TGTGGAACAA CGGTGGCGAT GAGGACTCTC TACCGAACCC GATACGGCAT TCCTGGGTCT 
ATTTGTGATG ACTACATGGT CACCCTCTTC TGTCCTGTTT GCTCTGTGTG CCAAATCAAG 
AGAGACATTA ACAGGAGGAG AGCCATGAAC GCTTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats.
Mammalian genome : official journal of the International Mammalian Genome Society26(11-12)619-29(2015 Dec)
Sasaki D,Kotoh J,Watadani R,Matsumoto K

Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.
Cell metabolism14(5)658-70(2011 Nov)
Jimenez-Preitner M,Berney X,Uldry M,Vitali A,Cinti S,Ledford JG,Thorens B

Impaired host defense in mice lacking ONZIN.
Journal of immunology (Baltimore, Md. : 1950)178(8)5132-43(2007 Apr)
Ledford JG,Kovarova M,Koller BH

The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1.
Molecular and cellular biology26(9)3401-13(2006 May)
Li Y,Rogulski K,Zhou Q,Sims PJ,Prochownik EV

Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.
Investigative ophthalmology & visual science43(11)3489-94(2002 Nov)
Yanagi Y,Takezawa S,Kato S