| Gene Symbol | Usp18 |
| Entrez Gene ID | 312688 |
| Full Name | ubiquitin specific peptidase 18 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Usp18 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Usp18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa04809 Clone ID Related Accession (Same CDS sequence) NM_001014058.1 Accession Version NM_001014058.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1089bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1555516800000 Organism Rattus norvegicus(Norway rat) Product ubl carboxyl-terminal hydrolase 18 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079101.1. On Apr 20, 2005 this sequence version replaced XM_232259.3. ##Evidence-Data-START## Transcript exon combination :: BC079101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGGCAAAG GGTTTGGGCT CCTGAGGAAA ACCTGCCAGT CAGTTGTGGC TAATCCTCAG
CAGCACTCAG CTCTGGAGGA AGAGAAGAAC ATGAAGAGGA AGAGAGTGCT GTCTAGAGAG
CTCTGCAGTG CCTGGGACCG CCCTCATGGT TTCGTTGGGT TACACAACAT CGGTCAGACA
TGTTGCCTTA ACTCCTTGAT TCAGGTGTTC ATGATGAATG TGGACTTCAG GATGGTATTG
AAGAGGATAA CAGTGCCACG AGGGGCAGAA GAACAGAAGA GAAGTGTCCC CTTCCAGCTG
CTTTTGCTGC TGGAGAAGAT GCAGGACAGC CGGCAGAAGG CAGTGCTGCC CACGGAGCTC
GTTCAGTGCC TCCAGAAATA CAACGTGCCA TTGTTTGTCC AGCACGATGC TGCTCATCTC
TTCCTTACAA TCTGGAACCT GACTAAGGAC CAGATCACGG ACATAGACTT GGCAGAGCGG
CTGCAGGATC TGTTCACAAT CTGGACCGAG GAGTCCCTGA TGTGCGTGGG CTGTGGAGCA
GAGAGCAGCA GGAGGGGCAA GTTGCTCACT CTCTCTCTTC CTCTTTTTGA TATGGATTCA
AAGCCCCTAA AAACACTGGA GGATGCCTTG AGATGTTTCT TCCAGCCCAA AGAGTTAGCA
AGCTCAGACA AGTGCTTCTG TGAGACCTGC GGGAAGAAGA CGCCTTGCAA ACAGGCTCAG
AAGCTGACTG GTTTCCCTCA GACCCTGACC ATCCACCTCA TGAGATTCTC TGTCAGGAAC
TCACAGACAG TAAAGATCTG CCACTCAGTG TACTTCCCGC AGAGCTTGGA TTTCAGTCAG
ATTCTGCCAA CCACGGATCA GTCTGAGATA CACTATGAAC TCTTTGCTGT GATTGCCCAT
GTTGGGATGG CAGACTTCGG TCATTACTGT GCCTACATCC GGAATCCCGT GGATGGAGAA
TGGTTCTGCT TCAATGATTC ACATGTTTGT TGGGTGACCT GGAAGGATGT CCAGTGTACC
TATGGGGATC ACATATATCG TTGGAGGGAA ACTGCCTATC TCTTGGTTTA CATGAAGACT
GGATCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001014080.1 CDS 119..1207 Translation 
Target ORF information:
RefSeq Version NM_001014058.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus ubiquitin specific peptidase 18 (Usp18), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001014058.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGGCAAAG GGTTTGGGCT CCTGAGGAAA ACCTGCCAGT CAGTTGTGGC TAATCCTCAG
CAGCACTCAG CTCTGGAGGA AGAGAAGAAC ATGAAGAGGA AGAGAGTGCT GTCTAGAGAG
CTCTGCAGTG CCTGGGACCG CCCTCATGGT TTCGTTGGGT TACACAACAT CGGTCAGACA
TGTTGCCTTA ACTCCTTGAT TCAGGTGTTC ATGATGAATG TGGACTTCAG GATGGTATTG
AAGAGGATAA CAGTGCCACG AGGGGCAGAA GAACAGAAGA GAAGTGTCCC CTTCCAGCTG
CTTTTGCTGC TGGAGAAGAT GCAGGACAGC CGGCAGAAGG CAGTGCTGCC CACGGAGCTC
GTTCAGTGCC TCCAGAAATA CAACGTGCCA TTGTTTGTCC AGCACGATGC TGCTCATCTC
TTCCTTACAA TCTGGAACCT GACTAAGGAC CAGATCACGG ACATAGACTT GGCAGAGCGG
CTGCAGGATC TGTTCACAAT CTGGACCGAG GAGTCCCTGA TGTGCGTGGG CTGTGGAGCA
GAGAGCAGCA GGAGGGGCAA GTTGCTCACT CTCTCTCTTC CTCTTTTTGA TATGGATTCA
AAGCCCCTAA AAACACTGGA GGATGCCTTG AGATGTTTCT TCCAGCCCAA AGAGTTAGCA
AGCTCAGACA AGTGCTTCTG TGAGACCTGC GGGAAGAAGA CGCCTTGCAA ACAGGCTCAG
AAGCTGACTG GTTTCCCTCA GACCCTGACC ATCCACCTCA TGAGATTCTC TGTCAGGAAC
TCACAGACAG TAAAGATCTG CCACTCAGTG TACTTCCCGC AGAGCTTGGA TTTCAGTCAG
ATTCTGCCAA CCACGGATCA GTCTGAGATA CACTATGAAC TCTTTGCTGT GATTGCCCAT
GTTGGGATGG CAGACTTCGG TCATTACTGT GCCTACATCC GGAATCCCGT GGATGGAGAA
TGGTTCTGCT TCAATGATTC ACATGTTTGT TGGGTGACCT GGAAGGATGT CCAGTGTACC
TATGGGGATC ACATATATCG TTGGAGGGAA ACTGCCTATC TCTTGGTTTA CATGAAGACT
GGATCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.
The Journal of experimental medicine213(7)1163-74(2016 06)
Meuwissen ME,Schot R,Buta S,Oudesluijs G,Tinschert S,Speer SD,Li Z,van Unen L,Heijsman D,Goldmann T,Lequin MH,Kros JM,Stam W,Hermann M,Willemsen R,Brouwer RW,Van IJcken WF,Martin-Fernandez M,de Coo I,Dudink J,de Vries FA,Bertoli Avella A,Prinz M,Crow YJ,Verheijen FW,Pellegrini S,Bogunovic D,Mancini GM
Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,Bécavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P
Resveratrol improves health and survival of mice on a high-calorie diet.
Nature444(7117)337-42(2006 Nov)
Baur JA,Pearson KJ,Price NL,Jamieson HA,Lerin C,Kalra A,Prabhu VV,Allard JS,Lopez-Lluch G,Lewis K,Pistell PJ,Poosala S,Becker KG,Boss O,Gwinn D,Wang M,Ramaswamy S,Fishbein KW,Spencer RG,Lakatta EG,Le Couteur D,Shaw RJ,Navas P,Puigserver P,Ingram DK,de Cabo R,Sinclair DA
Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling.
Molecular and cellular biology26(2)472-9(2006 Jan)
Kim KI,Yan M,Malakhova O,Luo JK,Shen MF,Zou W,de la Torre JC,Zhang DE
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Biochemical and biophysical research communications336(2)496-506(2005 Oct)
Giannakopoulos NV,Luo JK,Papov V,Zou W,Lenschow DJ,Jacobs BS,Borden EC,Li J,Virgin HW,Zhang DE
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