Tiparp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tiparp
Entrez Gene ID	310467
Full Name	TCDD-inducible poly(ADP-ribose) polymerase
Synonyms	RM1
General protein information	Preferred Names TCDD-inducible poly(ADP-ribose) polymerase Names TCDD-inducible poly [ADP-ribose] polymerase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q31

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107679.2	NP_001101149.2	TCDD-inducible poly [ADP-ribose] polymerase
XM_003753596.4	XP_003753644.1	TCDD-inducible poly [ADP-ribose] polymerase
XM_003749294.4	XP_003749342.1	TCDD-inducible poly [ADP-ribose] polymerase

Pathways from BioSystems

Homologies

Homo sapiens (human)	TIPARP	NP_001171646.1
Rattus norvegicus (Norway rat)	Tiparp	XP_003749342.1
Pan troglodytes (chimpanzee)	TIPARP	XP_001150766.1
Danio rerio (zebrafish)	tiparp	NP_001038484.1
Xenopus tropicalis (tropical clawed frog)	tiparp	NP_001106413.1
Macaca mulatta (Rhesus monkey)	TIPARP	XP_001104362.1
Canis lupus familiaris (dog)	TIPARP	XP_854837.2
Bos taurus (cattle)	TIPARP	NP_001192977.1
Mus musculus (house mouse)	Tiparp	NP_849223.2
Gallus gallus (chicken)	TIPARP	XP_422828.1

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity.
Gomez A, Bindesbøll C, Satheesh SV, Grimaldi G, Hutin D, MacPherson L, Ahmed S, Tamblyn L, Cho T, Nebb HI, Moen A, Anonsen JH, Grant DM, Matthews J
The Biochemical journal475(23)3827-3846(2018 12)

Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.
Barkauskaite E, Jankevicius G, Ahel I
Molecular cell58(6)935-46(2015 Jun)

Family-wide analysis of poly(ADP-ribose) polymerase activity.
Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I, Chang P
Nature communications54426(2014 Jul)

TCDD dysregulation of 13 AHR-target genes in rat liver.
Watson JD, Prokopec SD, Smith AB, Okey AB, Pohjanvirta R, Boutros PC
Toxicology and applied pharmacology274(3)445-54(2014 Feb)

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation.
MacPherson L, Tamblyn L, Rajendra S, Bralha F, McPherson JP, Matthews J
Nucleic acids research41(3)1604-21(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tiparp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tiparp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa15246	NM_001107679.2 Latest version!	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa15246	XM_003749294.4 Latest version!	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa15246	XM_003753596.4 Latest version!	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tiparp ( NM_001107679.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101149.2 Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Price & Availability↑

CloneID	ORa15246
Clone ID Related Accession (Same CDS sequence)	NM_001107679.2 , XM_003753596.4 , XM_003749294.4
Accession Version	NM_001107679.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565452800000
Organism	Rattus norvegicus(Norway rat)
Product	TCDD-inducible poly [ADP-ribose] polymerase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07011084.1 and BQ202544.1. On or before Aug 12, 2019 this sequence version replaced XM_003749294.4, XM_003753596.4, NM_001107679.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101149.2
CDS	256..2229
Translation	MDMETTDPEPDCVVQPPSPPDDFSCQMRISEKITPLKTCFKKKQEQKRLGTGTLRSLRPILNTLLESGSLDGVFRARDQNGDESSLHEHIVKKPLDINPACPPAENSMPVLIPDGTNVEGQLPEAHPSTDAPEQVVPIQDHSFPPETINGTVADSTTGHFQTDLLHPVSGDVPTSPDCIDKVMDYVPGAFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQETGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLSTPPCSSTNSIYHTFWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMSGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	NM_001107679.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107679.2

ORF Insert Sequence:

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tiparp ( XM_003753596.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_003753644.1 Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Price & Availability↑

CloneID	ORa15246
Clone ID Related Accession (Same CDS sequence)	NM_001107679.2 , XM_003753596.4 , XM_003749294.4
Accession Version	XM_003753596.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	TCDD-inducible poly [ADP-ribose] polymerase
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000070.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003753596.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003753644.1
CDS	251..2224
Translation	MDMETTDPEPDCVVQPPSPPDDFSCQMRISEKITPLKTCFKKKQEQKRLGTGTLRSLRPILNTLLESGSLDGVFRARDQNGDESSLHEHIVKKPLDINPACPPAENSMPVLIPDGTNVEGQLPEAHPSTDAPEQVVPIQDHSFPPETINGTVADSTTGHFQTDLLHPVSGDVPTSPDCIDKVMDYVPGAFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQETGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLSTPPCSSTNSIYHTFWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMSGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	XM_003753596.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003753596.4

ORF Insert Sequence:

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tiparp ( XM_003749294.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_003749342.1 Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Price & Availability↑

CloneID	ORa15246
Clone ID Related Accession (Same CDS sequence)	NM_001107679.2 , XM_003753596.4 , XM_003749294.4
Accession Version	XM_003749294.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	TCDD-inducible poly [ADP-ribose] polymerase
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003749294.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003749342.1
CDS	297..2270
Translation	MDMETTDPEPDCVVQPPSPPDDFSCQMRISEKITPLKTCFKKKQEQKRLGTGTLRSLRPILNTLLESGSLDGVFRARDQNGDESSLHEHIVKKPLDINPACPPAENSMPVLIPDGTNVEGQLPEAHPSTDAPEQVVPIQDHSFPPETINGTVADSTTGHFQTDLLHPVSGDVPTSPDCIDKVMDYVPGAFQDNSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQETGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLSTPPCSSTNSIYHTFWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMSGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	XM_003749294.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TCDD-inducible poly(ADP-ribose) polymerase (Tiparp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003749294.4

ORF Insert Sequence:

ATGGACATGG AAACCACCGA CCCTGAGCCA GACTGTGTAG TACAGCCTCC TTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGAATTTCT GAGAAGATCA CTCCATTGAA AACTTGTTTT 
AAGAAAAAGC AGGAACAGAA AAGATTGGGA ACTGGAACAT TGAGATCCTT AAGGCCAATA 
TTAAATACTT TGCTAGAATC TGGGTCGCTT GACGGAGTTT TTAGAGCCAG AGACCAAAAT 
GGAGATGAGA GCAGCTTACA TGAACATATA GTGAAAAAAC CTCTGGATAT CAACCCAGCA 
TGCCCACCAG CAGAAAACAG TATGCCTGTC CTGATTCCTG ATGGGACAAA TGTTGAGGGC 
CAATTACCAG AAGCTCATCC TTCTACTGAT GCTCCAGAAC AGGTGGTTCC AATCCAGGAT 
CACAGTTTTC CACCAGAAAC CATCAATGGC ACAGTAGCAG ATTCTACAAC AGGACACTTC 
CAAACTGACC TTTTGCATCC TGTTTCAGGT GATGTTCCTA CAAGTCCTGA CTGCATAGAT 
AAAGTTATGG ATTATGTGCC AGGAGCTTTC CAAGACAATA GTTTTACAAT CCAATACATT 
TTGGATACCA GTGACAAGTT GAGTACTGAG CTCTTCCAAG ACAAAAGTGA GGAAGCTTCC 
CTTGACCTTG TGTTTGAGCT TGTAAACCAG CTACAGTACC ATACTCACCA AGAGACTGGA 
ATTGAAATTT GTATGGACTT TCTGCAAGGC ACTTGCATTT ATGGCAGGGA TTGTTTGAAA 
CATCACACCG TATTGCCCTA TCATTGGCAG ATCAAAAGGA CAACCACTCA AAAGTGGCAG 
AGTGTTTCCA ATGATTCTCA GGAGCACTTG GAAAGATTTT ATTGTAATCC AGAAAATGAT 
AGAATGAGAA TGAAGTATGG AGGTCAAGAC TTTTGGGCAG ATTTGAATGC CATGACTGTA 
TTTGAAACAA CTGAATTTGA CCAACTACGA AGGCTGTCTA CACCACCTTG TAGTAGTACA 
AACTCTATTT ACCACACATT TTGGAAATTC TTCTGTAGAG ACCACTTTGG ATGGAGAGAG 
TATCCTGAGT CTGTTGTTCG ACTAATTGAA GAAGCCAACT CTCGGGGTCT GAAAGAAGTT 
AGATTTATGA TGTGGAACAA CCATTACATC CTCCACAACT CATTCTTCCG GAGAGAAATA 
AAACGGAGAC CCCTTTTTCG TTCCTGTTTC ATACTGATTC CATATTTACA GACACTTGGT 
GGGGTTCCCA CTCAGGCTTC TCTGCCTCTT GAAGCAACTT CATCACAAAT CATCTGTCCA 
GATGGAGTAA CTTCAGCAAA CTTTTACCCT GAAACATGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTGCCTGT TTCTGCAGAG GATAAAAGTT ATCGAATCAT TTACAACCTT 
TTTCATAAAA CTGTACCTGA ATTTAAATAC AGAATTTTAC AAATATTGAG AGTCCAAAAC 
CAATTTCTTT GGGAGAAATA TAAAAGGAAA AAAGAGTATA TGAATAGAAA AATGTCTGGC 
CGTGACAGAA TAATAAATGA GAGACACTTA TTTCATGGAA CATCACAAGA TGTGGTAGAT 
GGAATTTGCA AGCACAACTT TGACCCTCGT GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ACTTCGCGAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ATTTCATGTT TTTGGCCAAA GTGTTAACTG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC TCCGGTCAAC CCAGGCAGTG TCACCAGTGA CTTGTATGAC 
TCTTGTGTGG ATAATTTTTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity.
The Biochemical journal475(23)3827-3846(2018 12)
Gomez A,Bindesbøll C,Satheesh SV,Grimaldi G,Hutin D,MacPherson L,Ahmed S,Tamblyn L,Cho T,Nebb HI,Moen A,Anonsen JH,Grant DM,Matthews J

Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.
Molecular cell58(6)935-46(2015 Jun)
Barkauskaite E,Jankevicius G,Ahel I

Family-wide analysis of poly(ADP-ribose) polymerase activity.
Nature communications54426(2014 Jul)
Vyas S,Matic I,Uchima L,Rood J,Zaja R,Hay RT,Ahel I,Chang P

TCDD dysregulation of 13 AHR-target genes in rat liver.
Toxicology and applied pharmacology274(3)445-54(2014 Feb)
Watson JD,Prokopec SD,Smith AB,Okey AB,Pohjanvirta R,Boutros PC

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation.
Nucleic acids research41(3)1604-21(2013 Feb)
MacPherson L,Tamblyn L,Rajendra S,Bralha F,McPherson JP,Matthews J

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Tiparp cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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