Sars1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sars1
Entrez Gene ID	266975
Full Name	seryl-tRNA synthetase
Synonyms	Sars1
General protein information	Preferred Names seryl-tRNA synthetase Names serine--tRNA ligase, cytoplasmic serRS seryl-aminoacyl-tRNA synthetase 1 seryl-tRNA synthetase, cytoplasmic seryl-tRNA(Ser/Sec) synthetase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	mouse homolog is an RNA binding protein involved in catalyzing the transfer of L-serine to tRNA (Ser) [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006233136.2	XP_006233198.1	serine--tRNA ligase, cytoplasmic isoform X1
NM_001007606.1	NP_001007607.1	serine--tRNA ligase, cytoplasmic

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sars	NP_035449.1
Gallus gallus (chicken)	SARS	NP_001026563.1
Caenorhabditis elegans (roundworm)	sars-1	NP_501804.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008265	XP_317207.2
Rattus norvegicus (Norway rat)	Sars	NP_001007607.1
Danio rerio (zebrafish)	sars	NP_001003882.1
Bos taurus (cattle)	SARS	NP_776600.1
Drosophila melanogaster (fruit fly)	CG17259	NP_608743.2
Eremothecium gossypii	AGOS_ABL088C	NP_982859.1
Oryza sativa (rice)	Os01g0559100	NP_001043340.1
Neurospora crassa	NCU01443	XP_955965.2
Oryza sativa (rice)	Os03g0198400	NP_001049278.1
Schizosaccharomyces pombe (fission yeast)	SPAC29A4.15	NP_594867.1
Homo sapiens (human)	SARS	NP_006504.2
Kluyveromyces lactis	KLLA0A10593g	XP_451464.1
Magnaporthe oryzae (rice blast fungus)	MGG_06913	XP_003709647.1
Pan troglodytes (chimpanzee)	SARS	XP_001148840.1
Canis lupus familiaris (dog)	SARS	XP_866214.1
Saccharomyces cerevisiae (baker's yeast)	SES1	NP_010306.1
Arabidopsis thaliana (thale cress)	AT5G27470	NP_198099.1
Xenopus tropicalis (tropical clawed frog)	sars	NP_998852.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.
Musante L, Püttmann L, Kahrizi K, Garshasbi M, Hu H, Stehr H, Lipkowitz B, Otto S, Jensen LR, Tzschach A, Jamali P, Wienker T, Najmabadi H, Ropers HH, Kuss AW
Human mutation38(6)621-636(2017 06)

SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Wang C, Guo Y, Tian Q, Jia Q, Gao Y, Zhang Q, Zhou C, Xie W
Nucleic acids research43(21)10534-45(2015 Dec)

tRNA synthetase counteracts c-Myc to develop functional vasculature.
Shi Y, Xu X, Zhang Q, Fu G, Mo Z, Wang GS, Kishi S, Yang XL
eLife3e02349(2014 Jun)

Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes.
Xu X, Shi Y, Yang XL
Structure (London, England : 1993)21(11)2078-86(2013 Nov)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sars1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sars1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11098	NM_001007606.1 Latest version!	Rattus norvegicus seryl-tRNA synthetase 1 (Sars1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa25162	XM_006233136.2 Latest version!	Rattus norvegicus seryl-tRNA synthetase (Sars), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sars1 ( NM_001007606.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007607.1 Rattus norvegicus seryl-tRNA synthetase 1 (Sars1), mRNA.

Price & Availability↑

CloneID	ORa11098
Clone ID Related Accession (Same CDS sequence)	NM_001007606.1
Accession Version	NM_001007606.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565539200000
Organism	Rattus norvegicus(Norway rat)
Product	serine--tRNA ligase, cytoplasmic
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061765.1. On Nov 29, 2004 this sequence version replaced XM_342319.1. ##Evidence-Data-START## Transcript exon combination :: BC061765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGGTGCTGG ACCTGGACTT GTTTCGGGTG GATAAAGGAG GGGACCCAGC CCTCATTCGA 
GAGACGCAGG AGAAGCGCTT CAAAGATCCG GGGCTGGTGG ACCAGCTGGT GAAGGCAGAC 
AGCGAGTGGC GACGATGCAG ATTTCGGGCA GACAACTTGA ACAAGCTGAA GAATTTATGC 
AGCAAAACTA TTGGGGAGAA AATGAAGAAA AAAGAGCCAG TGGGAGAGGA CGAGTCCATC 
CCAGAGGATG TGCTGAATTT TGACGACCTC ACTGCAGACA CGTTAGCTGC CCTGAAAGTC 
TCACAAATTA AGAAAGTCCG ACTCCTCGTT GATGAAGCCA TCCAGAAGTG TGATGGGGAG 
CGGGTAAAGC TGGAAGCAGA GCGATTTGAG AACCTCCGAG AGATTGGGAA CCTTCTACAC 
CCCTCTGTGC CCATTAGTAA CGATGAGGAT GCAGACAACA AAGTAGAGCG TATTTGGGGT 
GATTGTACAG TCAGAAAGAA GTATTCCCAT GTGGACCTGG TGGTGATGGT GGATGGCTTT 
GAAGGCGAAA AGGGAGCCGT GGTGGCTGGT AGTCGGGGGT ACTTCCTGAA GGGGGTCCTG 
GTGTTCCTGG AGCAGGCACT TATCCAGTAT GCACTGCGCA CCTTGGGAAG CCGAGGCTAC 
ACTCCAATCT ACACCCCCTT CTTCATGAGG AAAGAGGTCA TGCAGGAAGT GGCCCAGCTC 
AGCCAGTTTG ATGAAGAACT CTATAAGGTG ATTGGCAAGG GCAGCGAAAA GAGCGATGAC 
AGCTCCTATG ACGAGAAGTA CTTGATTGCC ACCTCAGAAC AGCCCATCGC AGCTCTGCAC 
CGGGACGAGT GGCTGCGGCC AGAGGATCTG CCCATCAAGT ACGCCGGCTT CTCCACCTGC 
TTTCGGCAGG AAGTGGGTTC GCATGGCCGT GATACCCGTG GTATCTTTCG AGTCCATCAG 
TTTGAGAAGA TTGAACAGTT CGTGTACTCA TCACCTCATG ACAACAAGTC ATGGGAGATG 
TTTGATGAGA TGATCACCAC CGCAGAAGAA TTCTATCAGT CTTTGGGAAT CCCTTACCAC 
ATTGTGAATA TTGTCTCAGG CTCTTTGAAT CATGCTGCCA GCAAGAAGCT TGACCTGGAG 
GCCTGGTTCC CGGGCTCCGG TGCCTTCCGT GAGTTGGTTT CCTGTTCTAA CTGCACGGAT 
TACCAGGCTC GTCGGCTCCG AATCCGATAC GGGCAGACCA AGAAGATGAT GGACAAGGTG 
GAGTTTGTCC ATATGCTTAA TGCCACAATG TGTGCCACCA CCCGGACCAT CTGCGCCATC 
CTGGAGAACT ACCAGACAGA GAAGGGCATC GTCGTGCCAG AGAAGTTGAG GGAGTTCATG 
CCCCCAGGAC TCCAAGAACT GATCCCATTT GTGAAGCCAG CACCTATTGA CCAGGAGCCA 
TCTAAGAAGC AGAAGAAGCA ACATGAAGGC AGCAAAAAGA AAGCAAAAGA GGTCACCCTG 
GAGAACCAGC TGCAGAACAT GGAGGTCACT GAGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007607.1
CDS	59..1597
Translation	MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGEDESIPEDVLNFDDLTADTLAALKVSQIKKVRLLVDEAIQKCDGERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDSSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGFSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLREFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKAKEVTLENQLQNMEVTEA

Target ORF information:

RefSeq Version	NM_001007606.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus seryl-tRNA synthetase 1 (Sars1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007606.1

ORF Insert Sequence:

ATGGTGCTGG ACCTGGACTT GTTTCGGGTG GATAAAGGAG GGGACCCAGC CCTCATTCGA 
GAGACGCAGG AGAAGCGCTT CAAAGATCCG GGGCTGGTGG ACCAGCTGGT GAAGGCAGAC 
AGCGAGTGGC GACGATGCAG ATTTCGGGCA GACAACTTGA ACAAGCTGAA GAATTTATGC 
AGCAAAACTA TTGGGGAGAA AATGAAGAAA AAAGAGCCAG TGGGAGAGGA CGAGTCCATC 
CCAGAGGATG TGCTGAATTT TGACGACCTC ACTGCAGACA CGTTAGCTGC CCTGAAAGTC 
TCACAAATTA AGAAAGTCCG ACTCCTCGTT GATGAAGCCA TCCAGAAGTG TGATGGGGAG 
CGGGTAAAGC TGGAAGCAGA GCGATTTGAG AACCTCCGAG AGATTGGGAA CCTTCTACAC 
CCCTCTGTGC CCATTAGTAA CGATGAGGAT GCAGACAACA AAGTAGAGCG TATTTGGGGT 
GATTGTACAG TCAGAAAGAA GTATTCCCAT GTGGACCTGG TGGTGATGGT GGATGGCTTT 
GAAGGCGAAA AGGGAGCCGT GGTGGCTGGT AGTCGGGGGT ACTTCCTGAA GGGGGTCCTG 
GTGTTCCTGG AGCAGGCACT TATCCAGTAT GCACTGCGCA CCTTGGGAAG CCGAGGCTAC 
ACTCCAATCT ACACCCCCTT CTTCATGAGG AAAGAGGTCA TGCAGGAAGT GGCCCAGCTC 
AGCCAGTTTG ATGAAGAACT CTATAAGGTG ATTGGCAAGG GCAGCGAAAA GAGCGATGAC 
AGCTCCTATG ACGAGAAGTA CTTGATTGCC ACCTCAGAAC AGCCCATCGC AGCTCTGCAC 
CGGGACGAGT GGCTGCGGCC AGAGGATCTG CCCATCAAGT ACGCCGGCTT CTCCACCTGC 
TTTCGGCAGG AAGTGGGTTC GCATGGCCGT GATACCCGTG GTATCTTTCG AGTCCATCAG 
TTTGAGAAGA TTGAACAGTT CGTGTACTCA TCACCTCATG ACAACAAGTC ATGGGAGATG 
TTTGATGAGA TGATCACCAC CGCAGAAGAA TTCTATCAGT CTTTGGGAAT CCCTTACCAC 
ATTGTGAATA TTGTCTCAGG CTCTTTGAAT CATGCTGCCA GCAAGAAGCT TGACCTGGAG 
GCCTGGTTCC CGGGCTCCGG TGCCTTCCGT GAGTTGGTTT CCTGTTCTAA CTGCACGGAT 
TACCAGGCTC GTCGGCTCCG AATCCGATAC GGGCAGACCA AGAAGATGAT GGACAAGGTG 
GAGTTTGTCC ATATGCTTAA TGCCACAATG TGTGCCACCA CCCGGACCAT CTGCGCCATC 
CTGGAGAACT ACCAGACAGA GAAGGGCATC GTCGTGCCAG AGAAGTTGAG GGAGTTCATG 
CCCCCAGGAC TCCAAGAACT GATCCCATTT GTGAAGCCAG CACCTATTGA CCAGGAGCCA 
TCTAAGAAGC AGAAGAAGCA ACATGAAGGC AGCAAAAAGA AAGCAAAAGA GGTCACCCTG 
GAGAACCAGC TGCAGAACAT GGAGGTCACT GAGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sars1 ( XM_006233136.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006233198.1 Rattus norvegicus seryl-tRNA synthetase (Sars), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa25162
Clone ID Related Accession (Same CDS sequence)	XM_006233136.2
Accession Version	XM_006233136.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	serine--tRNA ligase, cytoplasmic isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006233136.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTGG ACCTGGACTT GTTTCGGGTG GATAAAGGAG GGGACCCAGC CCTCATTCGA 
GAGACGCAGG AGAAGCGCTT CAAAGATCCG GGGCTGGTGG ACCAGCTGGT GAAGGCAGAC 
AGCGAGTGGC GACGATGCAG ATTTCGGGCA GACAACTTGA ACAAGCTGAA GAATTTATGC 
AGCAAAACTA TTGGGGAGAA AATGAAGAAA AAAGAGCCAG TGGGAGAGGA CGAGTCCATC 
CCAGAGGATG TGCTGAATTT TGACGACCTC ACTGCAGACA CGTTAGCTGC CCTGAAAGTC 
TCACAAATTA AGAAAGTCCG ACTCCTCGTT GATGAAGCCA TCCAGAAGTG TGATGGGGAG 
CGGGTAAAGC TGGAAGCAGA GCGATTTGAG AACCTCCGAG AGATTGGGAA CCTTCTACAC 
CCCTCTGTGC CCATTAGTAA CGATGAGGAT GCAGACAACA AAGTAGAGCG TATTTGGGGT 
GATTGTACAG TCAGAAAGAA GTATTCCCAT GTGGACCTGG TGGTGATGGT GGATGGCTTT 
GAAGGCGAAA AGGGAGCCGT GGTGGCTGGT AGTCGGGGGT ACTTCCTGAA GGGGGTCCTG 
GTGTTCCTGG AGCAGGCACT TATCCAGTAT GCACTGCGCA CCTTGGGAAG CCGAGGCTAC 
ACTCCAATCT ACACCCCCTT CTTCATGAGG AAAGAGGTCA TGCAGGAAGT GGCCCAGCTC 
AGCCAGTTTG ATGAAGAACT CTATAAGGTG ATTGGCAAGG GCAGCGAAAA GAGCGATGAC 
AGCTCCTATG ACGAGAAGTA CTTGATTGCC ACCTCAGAAC AGCCCATCGC AGCTCTGCAC 
CGGGACGAGT GGCTGCGGCC AGAGGATCTG CCCATCAAGT ACGCCGGCTT CTCCACCTGC 
TTTCGGCAGG AAGTGGGTTC GCATGGCCGT GATACCCGTG GTATCTTTCG AGTCCATCAG 
TTTGAGAAGA TTGAACAGTT CGTGTACTCA TCACCTCATG ACAACAAGTC ATGGGAGATG 
TTTGATGAGA TGATCACCAC CGCAGAAGAA TTCTATCAGT CTTTGGGAAT CCCTTACCAC 
ATTGTGAATA TTGTCTCAGG CTCTTTGAAT CATGCTGCCA GCAAGAAGCT TGACCTGGAG 
GCCTGGTTCC CGGGCTCCGG TGCCTTCCGT GAGTTGGTTT CCTGTTCTAA CTGCACGGAT 
TACCAGGCTC GTCGGCTCCG AATCCGATAC GGGCAGACCA AGAAGATGAT GGACAAGAGG 
AAGAATAACC TCCGTTTCTC TACACAGAAC AAGTTGGAGG CAGTGTCTTC CCTCTTTTCG 
CCCAAGAAGG TGGAGTTTGT CCATATGCTT AATGCCACAA TGTGTGCCAC CACCCGGACC 
ATCTGCGCCA TCCTGGAGAA CTACCAGACA GAGAAGGGCA TCGTCGTGCC AGAGAAGTTG 
AGGGAGTTCA TGCCCCCAGG ACTCCAAGAA CTGATCCCAT TTGTGAAGCC AGCACCTATT 
GACCAGGAGC CATCTAAGAA GCAGAAGAAG CAACATGAAG GCAGCAAAAA GAAAGCAAAA 
GAGGTCACCC TGGAGAACCA GCTGCAGAAC ATGGAGGTCA CTGAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006233198.1
CDS	94..1704
Translation	MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGEDESIPEDVLNFDDLTADTLAALKVSQIKKVRLLVDEAIQKCDGERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDSSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGFSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKRKNNLRFSTQNKLEAVSSLFSPKKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLREFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKAKEVTLENQLQNMEVTEA

Target ORF information:

RefSeq Version	XM_006233136.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus seryl-tRNA synthetase (Sars), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006233136.2

ORF Insert Sequence:

ATGGTGCTGG ACCTGGACTT GTTTCGGGTG GATAAAGGAG GGGACCCAGC CCTCATTCGA 
GAGACGCAGG AGAAGCGCTT CAAAGATCCG GGGCTGGTGG ACCAGCTGGT GAAGGCAGAC 
AGCGAGTGGC GACGATGCAG ATTTCGGGCA GACAACTTGA ACAAGCTGAA GAATTTATGC 
AGCAAAACTA TTGGGGAGAA AATGAAGAAA AAAGAGCCAG TGGGAGAGGA CGAGTCCATC 
CCAGAGGATG TGCTGAATTT TGACGACCTC ACTGCAGACA CGTTAGCTGC CCTGAAAGTC 
TCACAAATTA AGAAAGTCCG ACTCCTCGTT GATGAAGCCA TCCAGAAGTG TGATGGGGAG 
CGGGTAAAGC TGGAAGCAGA GCGATTTGAG AACCTCCGAG AGATTGGGAA CCTTCTACAC 
CCCTCTGTGC CCATTAGTAA CGATGAGGAT GCAGACAACA AAGTAGAGCG TATTTGGGGT 
GATTGTACAG TCAGAAAGAA GTATTCCCAT GTGGACCTGG TGGTGATGGT GGATGGCTTT 
GAAGGCGAAA AGGGAGCCGT GGTGGCTGGT AGTCGGGGGT ACTTCCTGAA GGGGGTCCTG 
GTGTTCCTGG AGCAGGCACT TATCCAGTAT GCACTGCGCA CCTTGGGAAG CCGAGGCTAC 
ACTCCAATCT ACACCCCCTT CTTCATGAGG AAAGAGGTCA TGCAGGAAGT GGCCCAGCTC 
AGCCAGTTTG ATGAAGAACT CTATAAGGTG ATTGGCAAGG GCAGCGAAAA GAGCGATGAC 
AGCTCCTATG ACGAGAAGTA CTTGATTGCC ACCTCAGAAC AGCCCATCGC AGCTCTGCAC 
CGGGACGAGT GGCTGCGGCC AGAGGATCTG CCCATCAAGT ACGCCGGCTT CTCCACCTGC 
TTTCGGCAGG AAGTGGGTTC GCATGGCCGT GATACCCGTG GTATCTTTCG AGTCCATCAG 
TTTGAGAAGA TTGAACAGTT CGTGTACTCA TCACCTCATG ACAACAAGTC ATGGGAGATG 
TTTGATGAGA TGATCACCAC CGCAGAAGAA TTCTATCAGT CTTTGGGAAT CCCTTACCAC 
ATTGTGAATA TTGTCTCAGG CTCTTTGAAT CATGCTGCCA GCAAGAAGCT TGACCTGGAG 
GCCTGGTTCC CGGGCTCCGG TGCCTTCCGT GAGTTGGTTT CCTGTTCTAA CTGCACGGAT 
TACCAGGCTC GTCGGCTCCG AATCCGATAC GGGCAGACCA AGAAGATGAT GGACAAGAGG 
AAGAATAACC TCCGTTTCTC TACACAGAAC AAGTTGGAGG CAGTGTCTTC CCTCTTTTCG 
CCCAAGAAGG TGGAGTTTGT CCATATGCTT AATGCCACAA TGTGTGCCAC CACCCGGACC 
ATCTGCGCCA TCCTGGAGAA CTACCAGACA GAGAAGGGCA TCGTCGTGCC AGAGAAGTTG 
AGGGAGTTCA TGCCCCCAGG ACTCCAAGAA CTGATCCCAT TTGTGAAGCC AGCACCTATT 
GACCAGGAGC CATCTAAGAA GCAGAAGAAG CAACATGAAG GCAGCAAAAA GAAAGCAAAA 
GAGGTCACCC TGGAGAACCA GCTGCAGAAC ATGGAGGTCA CTGAGGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.
Human mutation38(6)621-636(2017 06)
Musante L,Püttmann L,Kahrizi K,Garshasbi M,Hu H,Stehr H,Lipkowitz B,Otto S,Jensen LR,Tzschach A,Jamali P,Wienker T,Najmabadi H,Ropers HH,Kuss AW

SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic acids research43(21)10534-45(2015 Dec)
Wang C,Guo Y,Tian Q,Jia Q,Gao Y,Zhang Q,Zhou C,Xie W

tRNA synthetase counteracts c-Myc to develop functional vasculature.
eLife3e02349(2014 Jun)
Shi Y,Xu X,Zhang Q,Fu G,Mo Z,Wang GS,Kishi S,Yang XL

Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes.
Structure (London, England : 1993)21(11)2078-86(2013 Nov)
Xu X,Shi Y,Yang XL

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

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Sars1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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