Csn1s1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Csn1s1
Entrez Gene ID	24284
Full Name	casein alpha s1
Synonyms	Casa,Csn1,Csna
General protein information	Preferred Names casein alpha s1 Names alpha-S1-casein Casein, alpha alpha-casein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p21
Summary	milk phosphoprotein; expression is regulated by steroid and peptide hormones [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_138874.2	NP_620229.2	alpha-S1-casein precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

AlphaS1-casein, which is essential for efficient ER-to-Golgi casein transport, is also present in a tightly membrane-associated form.
Le Parc A, Leonil J, Chanat E
BMC cell biology1165(2010 Aug)

Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
Palmer DJ, Kelly VC, Smit AM, Kuy S, Knight CG, Cooper GJ
Proteomics6(7)2208-16(2006 Apr)

Expression of the whey acidic protein (Wap) is necessary for adequate nourishment of the offspring but not functional differentiation of mammary epithelial cells.
Triplett AA, Sakamoto K, Matulka LA, Shen L, Smith GH, Wagner KU
Genesis (New York, N.Y. : 2000)43(1)1-11(2005 Sep)

Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions.
Yu-Lee LY, Richter-Mann L, Couch CH, Stewart AF, Mackinlay AG, Rosen JM
Nucleic acids research14(4)1883-902(1986 Feb)

Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family.
Hobbs AA, Rosen JM
Nucleic acids research10(24)8079-98(1982 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Csn1s1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Csn1s1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01833	NM_138874.2 Latest version!	Rattus norvegicus casein alpha s1 (Csn1s1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Csn1s1 ( NM_138874.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620229.2 Rattus norvegicus casein alpha s1 (Csn1s1), mRNA.

Price & Availability↑

CloneID	ORa01833
Clone ID Related Accession (Same CDS sequence)	NM_138874.2
Accession Version	NM_138874.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	alpha-S1-casein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J00710.1. On Jun 27, 2003 this sequence version replaced NM_138874.1. ##Evidence-Data-START## Transcript exon combination :: J00710.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689594, SAMEA2689597 [ECO:0000350] ##Evidence-Data-END##

ATGAAACTTC TTATCCTCAC CTGCCTCGTG GCTGCTGCTC TTGCTCTGCC TAGAGCTCAT 
CGTAGAAATG CAGTCAGCAG TCAAACTCAG CAAGAGAATA GCAGCAGTGA GGAACAGGAA 
ATTGTTAAAC AACCAAAGTA TCTCAGTCTT AATGAGGAGT TCGTCAACAA CCTGAACAGA 
CAGAGAGAGC TTCTGACAGA ACAGGATAAT GAAATCAAGA TAACTATGGA CTCATCAGCT 
GAGGAACAAG CAACGGCAAG TGCTCAGGAA GATTCCTCCT CAAGCAGCTC ATCAAGCGAG 
GAATCCAAGG ATGCTATTCC CAGTGCTACT GAGCAGAAAA ACATTGCAAA CAAAGAAATA 
CTCAACCGAT GCACCCTGGA ACAGCTTCAG AGACAGATTA AATACAGCCA ACTTCTCCAG 
CAAGCTTCAC TGGCTCAGCA AGCTTCCCTG GCTCAGCAAG CTTCCTTGGC CCAGCAAGCT 
CTCCTGGCCC AGCAACCTTC CCTGGCACAG CAAGCTGCCC TGGCACAGCA AGCTTCCCTG 
GCACAGCAAG CTTCCCTGGC ACAGCAAGCT TCCCTGGCAC AGAAACATCA TCCAAGACTG 
AGCCAGGTCT ACTATCCAAA TATGGAACAA CCTTACAGGA TGAATGCATA CAGCCAAGTT 
CAGATGAGAC ATCCTATGAG TGTAGTGGAT CAGGCCCAGT TCTCTGTTCA GTCTTTCCCA 
CAACTCTCCC AATATGGCGC CTATCCCCTT TGGCTTTACT TTCCACAAGA CATGCAGTAC 
CTTACCCCTG AAGCTGTTCT TAACACCTTC AAGCCCATTG CCCCCAAGGA TGCTGAAAAC 
ACCAATGTGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620229.2
CDS	62..916
Translation	MKLLILTCLVAAALALPRAHRRNAVSSQTQQENSSSEEQEIVKQPKYLSLNEEFVNNLNRQRELLTEQDNEIKITMDSSAEEQATASAQEDSSSSSSSSEESKDAIPSATEQKNIANKEILNRCTLEQLQRQIKYSQLLQQASLAQQASLAQQASLAQQALLAQQPSLAQQAALAQQASLAQQASLAQQASLAQKHHPRLSQVYYPNMEQPYRMNAYSQVQMRHPMSVVDQAQFSVQSFPQLSQYGAYPLWLYFPQDMQYLTPEAVLNTFKPIAPKDAENTNVW

Target ORF information:

RefSeq Version	NM_138874.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus casein alpha s1 (Csn1s1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138874.2

ORF Insert Sequence:

ATGAAACTTC TTATCCTCAC CTGCCTCGTG GCTGCTGCTC TTGCTCTGCC TAGAGCTCAT 
CGTAGAAATG CAGTCAGCAG TCAAACTCAG CAAGAGAATA GCAGCAGTGA GGAACAGGAA 
ATTGTTAAAC AACCAAAGTA TCTCAGTCTT AATGAGGAGT TCGTCAACAA CCTGAACAGA 
CAGAGAGAGC TTCTGACAGA ACAGGATAAT GAAATCAAGA TAACTATGGA CTCATCAGCT 
GAGGAACAAG CAACGGCAAG TGCTCAGGAA GATTCCTCCT CAAGCAGCTC ATCAAGCGAG 
GAATCCAAGG ATGCTATTCC CAGTGCTACT GAGCAGAAAA ACATTGCAAA CAAAGAAATA 
CTCAACCGAT GCACCCTGGA ACAGCTTCAG AGACAGATTA AATACAGCCA ACTTCTCCAG 
CAAGCTTCAC TGGCTCAGCA AGCTTCCCTG GCTCAGCAAG CTTCCTTGGC CCAGCAAGCT 
CTCCTGGCCC AGCAACCTTC CCTGGCACAG CAAGCTGCCC TGGCACAGCA AGCTTCCCTG 
GCACAGCAAG CTTCCCTGGC ACAGCAAGCT TCCCTGGCAC AGAAACATCA TCCAAGACTG 
AGCCAGGTCT ACTATCCAAA TATGGAACAA CCTTACAGGA TGAATGCATA CAGCCAAGTT 
CAGATGAGAC ATCCTATGAG TGTAGTGGAT CAGGCCCAGT TCTCTGTTCA GTCTTTCCCA 
CAACTCTCCC AATATGGCGC CTATCCCCTT TGGCTTTACT TTCCACAAGA CATGCAGTAC 
CTTACCCCTG AAGCTGTTCT TAACACCTTC AAGCCCATTG CCCCCAAGGA TGCTGAAAAC 
ACCAATGTGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

AlphaS1-casein, which is essential for efficient ER-to-Golgi casein transport, is also present in a tightly membrane-associated form.
BMC cell biology1165(2010 Aug)
Le Parc A,Leonil J,Chanat E

Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
Proteomics6(7)2208-16(2006 Apr)
Palmer DJ,Kelly VC,Smit AM,Kuy S,Knight CG,Cooper GJ

Expression of the whey acidic protein (Wap) is necessary for adequate nourishment of the offspring but not functional differentiation of mammary epithelial cells.
Genesis (New York, N.Y. : 2000)43(1)1-11(2005 Sep)
Triplett AA,Sakamoto K,Matulka LA,Shen L,Smith GH,Wagner KU

Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions.
Nucleic acids research14(4)1883-902(1986 Feb)
Yu-Lee LY,Richter-Mann L,Couch CH,Stewart AF,Mackinlay AG,Rosen JM

Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family.
Nucleic acids research10(24)8079-98(1982 Dec)
Hobbs AA,Rosen JM