IL10 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL10
Entrez Gene ID	443342
Full Name	interleukin 10
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009327.1	NP_001009327.1	interleukin-10 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Tumor Necrosis Factor-α, Interleukins-12(p40), 6, and 10 levels in cerebrospinal fluid and outcome prediction in Ossimi sheep with encephalitic listeriosis.
Abdlla OA, Elboshy ME, Reisha EF, Gadlla HA, El-Khodery SA
Cytokine73(2)283-7(2015 Jun)

IL-10 and TGF-beta1 are associated with variations in fluke burdens following experimental fasciolosis in sheep.
Haçariz O, Sayers G, Flynn RJ, Lejeune A, Mulcahy G
Parasite immunology31(10)613-22(2009 Oct)

Cloning and characterisation of an ovine interleukin-10-encoding cDNA.
Martin HM, Nash AD, Andrews AE
Gene159(2)187-91(1995 Jul)

Sequence of the sheep interleukin-10-encoding cDNA.
Dutia BM, Hunt P, Sargan DR, Dalziel RG, Hopkins J
Gene149(2)393-4(1994 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IL10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm00054	NM_001009327.1 Latest version!	Ovis aries interleukin 10 (IL10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL10 ( NM_001009327.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001009327.1 Ovis aries interleukin 10 (IL10), mRNA.

Price & Availability↑

CloneID	OSm00054
Clone ID Related Accession (Same CDS sequence)	NM_001009327.1
Accession Version	NM_001009327.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Ovis aries(sheep)
Product	interleukin-10 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U11421.1. ##Evidence-Data-START## Transcript exon combination :: U11421.1, Z29362.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104495058 [ECO:0000348] ##Evidence-Data-END##

ATGCCCAGCA GCTCAGCCGT GCTCTGTTGC CTGGTCTTCC TGGCTGGGGT GGCAGCCAGC 
CGAGATGCCA GCACCCTGTC TGACAGCAGC TGTACCCACT TCCCAGCCAG CCTGCCCCAC 
ATGCTGCGGG ACGTCCGAGC TGCCTTCGGC AAAGTGAAGA CTTTCTTTCA AATGAAGGAC 
CAACTGAACA GCATGCTGTT GACCCAGTCT CTGCTGGATG ACTTTAAGGG TTACCTGGGT 
TGCCAAGCCT TGTCGGAAAT GATCCAGTTT TACCTGGAGG AGGTGATGCC ACAGGCTGAG 
AACCATGGGC CTGACATCAA GGAGCACGTG AACTCGCTGG GGGAGAAGCT GAAGACCCTC 
CGGCTGCGGC TGCGGCGCTG TCATCGTTTT CTGCCCTGCG AAAACAAGAG CAAGGCGGTG 
GAGCAGGTGA AGAGAGTCTT CAATATGCTC CAAGAGAGGG GTGTCTACAA AGCCATGAGT 
GAGTTTGACA TCTTCATCAA CTACATAGAA TCCTACATGA CAACGAAGAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009327.1
CDS	16..549
Translation	MPSSSAVLCCLVFLAGVAASRDASTLSDSSCTHFPASLPHMLRDVRAAFGKVKTFFQMKDQLNSMLLTQSLLDDFKGYLGCQALSEMIQFYLEEVMPQAENHGPDIKEHVNSLGEKLKTLRLRLRRCHRFLPCENKSKAVEQVKRVFNMLQERGVYKAMSEFDIFINYIESYMTTKM

Target ORF information:

RefSeq Version	NM_001009327.1
Organism	Ovis aries(sheep)
Definition	Ovis aries interleukin 10 (IL10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009327.1

ORF Insert Sequence:

ATGCCCAGCA GCTCAGCCGT GCTCTGTTGC CTGGTCTTCC TGGCTGGGGT GGCAGCCAGC 
CGAGATGCCA GCACCCTGTC TGACAGCAGC TGTACCCACT TCCCAGCCAG CCTGCCCCAC 
ATGCTGCGGG ACGTCCGAGC TGCCTTCGGC AAAGTGAAGA CTTTCTTTCA AATGAAGGAC 
CAACTGAACA GCATGCTGTT GACCCAGTCT CTGCTGGATG ACTTTAAGGG TTACCTGGGT 
TGCCAAGCCT TGTCGGAAAT GATCCAGTTT TACCTGGAGG AGGTGATGCC ACAGGCTGAG 
AACCATGGGC CTGACATCAA GGAGCACGTG AACTCGCTGG GGGAGAAGCT GAAGACCCTC 
CGGCTGCGGC TGCGGCGCTG TCATCGTTTT CTGCCCTGCG AAAACAAGAG CAAGGCGGTG 
GAGCAGGTGA AGAGAGTCTT CAATATGCTC CAAGAGAGGG GTGTCTACAA AGCCATGAGT 
GAGTTTGACA TCTTCATCAA CTACATAGAA TCCTACATGA CAACGAAGAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor Necrosis Factor-α, Interleukins-12(p40), 6, and 10 levels in cerebrospinal fluid and outcome prediction in Ossimi sheep with encephalitic listeriosis.
Cytokine73(2)283-7(2015 Jun)
Abdlla OA,Elboshy ME,Reisha EF,Gadlla HA,El-Khodery SA

IL-10 and TGF-beta1 are associated with variations in fluke burdens following experimental fasciolosis in sheep.
Parasite immunology31(10)613-22(2009 Oct)
Haçariz O,Sayers G,Flynn RJ,Lejeune A,Mulcahy G

Cloning and characterisation of an ovine interleukin-10-encoding cDNA.
Gene159(2)187-91(1995 Jul)
Martin HM,Nash AD,Andrews AE

Sequence of the sheep interleukin-10-encoding cDNA.
Gene149(2)393-4(1994 Nov)
Dutia BM,Hunt P,Sargan DR,Dalziel RG,Hopkins J