OVAR-DRB1 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	OVAR-DRB1
Entrez Gene ID	101119342
Full Name	DLA class II histocompatibility antigen, DR-1 beta chain-like
Synonyms	DRB1
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001280698.1	NP_001267627.1	DLA class II histocompatibility antigen, DR-1 beta chain-like precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Ovar-DRB1 haplotypes *2001 and *0301 are associated with sheep growth and ewe lifetime prolificacy.
Cinar MU, Mousel MR, Herrmann-Hoesing LM, Taylor JB, White SN
Gene595(2)187-192(2016 Dec)

Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1.
Herrmann-Hoesing LM, White SN, Mousel MR, Lewis GS, Knowles DP
Immunogenetics60(12)749-58(2008 Dec)

Genomic organisation and allelic diversity within coding and non-coding regions of the Ovar-DRB1 locus.
Ballingall KT, Fardoe K, McKeever DJ
Immunogenetics60(2)95-103(2008 Feb)

Gene expression profiling during increased fetal lung expansion identifies genes likely to regulate development of the distal airways.
Sozo F, Wallace MJ, Zahra VA, Filby CE, Hooper SB
Physiological genomics24(2)105-13(2006 Jan)

Identification and phylogenetic analysis of 15 MHC class II DRB1 beta1 expressed alleles in a ewe-lamb flock.
Herrmann LM, Brown WC, Lewis GS, Knowles DP
Immunogenetics57(11)855-63(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following OVAR-DRB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OVAR-DRB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm21502	NM_001280698.1 Latest version!	Ovis aries DLA class II histocompatibility antigen, DR-1 beta chain-like (OVAR-DRB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OVAR-DRB1 ( NM_001280698.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001267627.1 Ovis aries DLA class II histocompatibility antigen, DR-1 beta chain-like (OVAR-DRB1), mRNA.

Price & Availability↑

CloneID	OSm21502
Clone ID Related Accession (Same CDS sequence)	NM_001280698.1
Accession Version	NM_001280698.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1549641600000
Organism	Ovis aries(sheep)
Product	DLA class II histocompatibility antigen, DR-1 beta chain-like precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JQ824380.1. On Jul 23, 2013 this sequence version replaced XM_004019245.1. ##Evidence-Data-START## Transcript exon combination :: JQ824380.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104494974, SAMEA104494976 [ECO:0000348] ##Evidence-Data-END##

ATGGTGTGCC TGTATTTCTC CAGAGGCTCC CGGATGGCAG CTCTGATAGT GATGCTGATG 
GCGCTGAGCC CTCCCCTGGC CTGGGCCAGG AAGATCCAAC CACATTTCTT GGAGTATACT 
AAGAAAGAGT GTCGTTTCTC CAACGGGACG GAGCGGGTGC GGTTCCTGGA CAGATACTTC 
TATAATGGAG AAGAGTACGC GCGCTTCGAC AGCGACTGGG GCGAGTACCG AGCGGTGGCC 
GAGCTGGGGC GGCGGAGCGC CGAGTACTGG AACAGCCAGA AGGAGATCCT GGAGCGGAAG 
CGGGCCGCCG TGGACACGTA CTGCAGACAC AACTACGGGG TCGGTGAGAG TTTCACTGTG 
CAGCGGCGAG TGGAGCCTAT AGTGACTGTG TATCCTGCAA AGACCCAGCC CCTGCAGCAC 
CACAACCTCC TGGTCTGCTC TGTGAATGGA TTCTACCCAG GCCACATTGA AGTCAGGTGG 
TTCCGGAACG GCCACGAAGA GGAGGCTGGG GTGATCTCCA CAGGCCTGAT CCAGAATGGA 
GACTGGACCT TCCAGACCAT GGTGATGCTT GAAACAGTTC CTCAGAGTGG AGAGGTCTAC 
ACCTGCCAAG TGGATCACCC CAGCCGGACG AGCCCTATCA CAGTGGAATG GAGGGCACGG 
TCTGACTCAG CTCAGAGCAA GATGATGAGT GGAGTTGGGG GCTTTGTTCT GGGTCTGCTC 
TTCCTTGCGG TGGGGCTCTT CATCTACTTC AGGAATCAGA AAGGACGCCC TACCCTTCAG 
CCAACAGGGC TCCTGAGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001267627.1
CDS	39..839
Translation	MVCLYFSRGSRMAALIVMLMALSPPLAWARKIQPHFLEYTKKECRFSNGTERVRFLDRYFYNGEEYARFDSDWGEYRAVAELGRRSAEYWNSQKEILERKRAAVDTYCRHNYGVGESFTVQRRVEPIVTVYPAKTQPLQHHNLLVCSVNGFYPGHIEVRWFRNGHEEEAGVISTGLIQNGDWTFQTMVMLETVPQSGEVYTCQVDHPSRTSPITVEWRARSDSAQSKMMSGVGGFVLGLLFLAVGLFIYFRNQKGRPTLQPTGLLS

Target ORF information:

RefSeq Version	NM_001280698.1
Organism	Ovis aries(sheep)
Definition	Ovis aries DLA class II histocompatibility antigen, DR-1 beta chain-like (OVAR-DRB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001280698.1

ORF Insert Sequence:

ATGGTGTGCC TGTATTTCTC CAGAGGCTCC CGGATGGCAG CTCTGATAGT GATGCTGATG 
GCGCTGAGCC CTCCCCTGGC CTGGGCCAGG AAGATCCAAC CACATTTCTT GGAGTATACT 
AAGAAAGAGT GTCGTTTCTC CAACGGGACG GAGCGGGTGC GGTTCCTGGA CAGATACTTC 
TATAATGGAG AAGAGTACGC GCGCTTCGAC AGCGACTGGG GCGAGTACCG AGCGGTGGCC 
GAGCTGGGGC GGCGGAGCGC CGAGTACTGG AACAGCCAGA AGGAGATCCT GGAGCGGAAG 
CGGGCCGCCG TGGACACGTA CTGCAGACAC AACTACGGGG TCGGTGAGAG TTTCACTGTG 
CAGCGGCGAG TGGAGCCTAT AGTGACTGTG TATCCTGCAA AGACCCAGCC CCTGCAGCAC 
CACAACCTCC TGGTCTGCTC TGTGAATGGA TTCTACCCAG GCCACATTGA AGTCAGGTGG 
TTCCGGAACG GCCACGAAGA GGAGGCTGGG GTGATCTCCA CAGGCCTGAT CCAGAATGGA 
GACTGGACCT TCCAGACCAT GGTGATGCTT GAAACAGTTC CTCAGAGTGG AGAGGTCTAC 
ACCTGCCAAG TGGATCACCC CAGCCGGACG AGCCCTATCA CAGTGGAATG GAGGGCACGG 
TCTGACTCAG CTCAGAGCAA GATGATGAGT GGAGTTGGGG GCTTTGTTCT GGGTCTGCTC 
TTCCTTGCGG TGGGGCTCTT CATCTACTTC AGGAATCAGA AAGGACGCCC TACCCTTCAG 
CCAACAGGGC TCCTGAGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ovar-DRB1 haplotypes *2001 and *0301 are associated with sheep growth and ewe lifetime prolificacy.
Gene595(2)187-192(2016 Dec)
Cinar MU,Mousel MR,Herrmann-Hoesing LM,Taylor JB,White SN

Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1.
Immunogenetics60(12)749-58(2008 Dec)
Herrmann-Hoesing LM,White SN,Mousel MR,Lewis GS,Knowles DP

Genomic organisation and allelic diversity within coding and non-coding regions of the Ovar-DRB1 locus.
Immunogenetics60(2)95-103(2008 Feb)
Ballingall KT,Fardoe K,McKeever DJ

Gene expression profiling during increased fetal lung expansion identifies genes likely to regulate development of the distal airways.
Physiological genomics24(2)105-13(2006 Jan)
Sozo F,Wallace MJ,Zahra VA,Filby CE,Hooper SB

Identification and phylogenetic analysis of 15 MHC class II DRB1 beta1 expressed alleles in a ewe-lamb flock.
Immunogenetics57(11)855-63(2005 Dec)
Herrmann LM,Brown WC,Lewis GS,Knowles DP