Gene Symbol | F8 |
Entrez Gene ID | 100359363 |
Full Name | coagulation factor VIII, procoagulant component |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
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ORF » Species Summary » Ovis aries » F8 cDNA ORF clone
Gene Symbol | F8 |
Entrez Gene ID | 100359363 |
Full Name | coagulation factor VIII, procoagulant component |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
mRNA | Protein | Name |
---|---|---|
NM_001172550.1 | NP_001166021.1 | coagulation factor VIII precursor |
XM_027962756.1 | XP_027818557.1 | coagulation factor VIII isoform X1 |
XM_012106122.1 | XP_011961512.1 | coagulation factor VIII isoform X1 |
Expanding the ortholog approach for hemophilia treatment complicated by factor VIII inhibitors.
Zakas PM, Vanijcharoenkarn K, Markovitz RC, Meeks SL, Doering CB
Journal of thrombosis and haemostasis : JTH13(1)72-81(2015 Jan)
Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.
Porada CD, Sanada C, Long CR, Wood JA, Desai J, Frederick N, Millsap L, Bormann C, Menges SL, Hanna C, Flores-Foxworth G, Shin T, Westhusin ME, Liu W, Glimp H, Zanjani ED, Lozier JN, Pliska V, Stranzinger G, Joerg H, Kraemer DC, Almeida-Porada G
Journal of thrombosis and haemostasis : JTH8(2)276-85(2010 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following F8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSm21382 | |
Clone ID Related Accession (Same CDS sequence) | NM_001172550.1 | |
Accession Version | NM_001172550.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6765bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1549641600000 | |
Organism | Ovis aries(sheep) | |
Product | coagulation factor VIII precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from GQ200609.1. ##Evidence-Data-START## Transcript exon combination :: GQ200609.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA104494974, SAMEA104494976 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001166021.1 |
CDS | 1..6765 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm22529 | |
Clone ID Related Accession (Same CDS sequence) | XM_012106122.1 | |
Accession Version | XM_012106122.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1450195200000 | |
Organism | Ovis aries(sheep) | |
Product | coagulation factor VIII isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011961512.1 |
CDS | 699..7472 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm84973 | |
Clone ID Related Accession (Same CDS sequence) | XM_027962756.1 | |
Accession Version | XM_027962756.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6009bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1549296000000 | |
Organism | Ovis aries(sheep) | |
Product | coagulation factor VIII isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040278.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_027818557.1 |
CDS | 185..6193 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCACATCA AGCTCTGTAC CTGCCTCTTT CTGTGCCTCT GGCCATGCAG CTTCAGTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Expanding the ortholog approach for hemophilia treatment complicated by factor VIII inhibitors. |
Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A. |