HCN4 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	HCN4
Entrez Gene ID	100009452
Full Name	hyperpolarization activated cyclic nucleotide gated potassium channel 4
Synonyms	HAC4
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082707.1	NP_001076176.1	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

HCN4-Overexpressing Mouse Embryonic Stem Cell-Derived Cardiomyocytes Generate a New Rapid Rhythm in Rats with Bradycardia.
Saito Y, Nakamura K, Yoshida M, Sugiyama H, Takano M, Nagase S, Morita H, Kusano KF, Ito H
International heart journal59(3)601-606(2018 May)

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.
Brioschi C, Micheloni S, Tellez JO, Pisoni G, Longhi R, Moroni P, Billeter R, Barbuti A, Dobrzynski H, Boyett MR, DiFrancesco D, Baruscotti M
Journal of molecular and cellular cardiology47(2)221-7(2009 Aug)

[Experimental study on influence of ischemia-reperfusion on expression of hyperpolarization activated cyclic nucleotide gated cation channel 4 of sinoatrial node cells in rabbits in vivo].
Fu Y, Liao B, Yu F, Deng M, Feng Z, Zhan F, Li X, Wan J
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery23(7)856-60(2009 Jul)

In situ co-distribution and functional interactions of SAP97 with sinoatrial isoforms of HCN channels.
Peters CJ, Chow SS, Angoli D, Nazzari H, Cayabyab FS, Morshedian A, Accili EA
Journal of molecular and cellular cardiology46(5)636-43(2009 May)

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues.
Shi W, Wymore R, Yu H, Wu J, Wymore RT, Pan Z, Robinson RB, Dixon JE, McKinnon D, Cohen IS
Circulation research85(1)e1-6(1999 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HCN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HCN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOb00207	NM_001082707.1 Latest version!	Oryctolagus cuniculus hyperpolarization activated cyclic nucleotide gated potassium channel 4 (HCN4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HCN4 ( NM_001082707.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001076176.1 Oryctolagus cuniculus hyperpolarization activated cyclic nucleotide gated potassium channel 4 (HCN4), mRNA.

Price & Availability↑

CloneID	OOb00207
Clone ID Related Accession (Same CDS sequence)	NM_001082707.1
Accession Version	NM_001082707.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Oryctolagus cuniculus(rabbit)
Product	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB022927.2. ##Evidence-Data-START## Transcript exon combination :: AB022927.2 [ECO:0000332] ##Evidence-Data-END##

ATGGACAAGC TGCCGCCGTC CATGCGCAAG CGGCTGTACA GCCTCCCGCA GCAGGTGGGG 
GCCAAGGCGT GGATCATGGA CGAGGAGGAG GACGCCGAAG AAGAGGGCGC CGGGGGCCGC 
CAGGATCCCC GCCGCAGGAG CATCCGGCTG CGGCCGCTGC CCTCGCCCTC GCCCTCGCCC 
TCCGCGGCGG CGGCGGCGGC GGGCGGCGCG GAGTCCCGGG GCGCGGCCCT CGGAGGGGCG 
GCGGACGGCG AGGGGCCGGC CCGGGGCGCG GCCAAGTCCA GCACGAACGG CGACTGCAGG 
CGCTTCCGCG GGAGCCTGGC CTCGCTGGGC AGCCGTGGCG GCGGCGGCGG CGGCGGCAGC 
ACGGGCGGCG GCAGCCACGG GCACCTGCAT GACTCCGCCG AAGAGCGGCG GCTCATCGCC 
GAGGGCGACG CGTCCCCCGG CGAGGACAGG ACGCCCCCGG GCCTGGCGGC CGAGCCGGAG 
CGCCCGGGAG CCCCGGCGCC GCCCGCAGCC TCGCCGCCGC AGGTGCCCTC GTCCTGCGGC 
GAGCAGCGCC CGGCCGACGC GGCTGTCAAA GTGGAGGGAG GCGCGGCCGC GGGCGACCAG 
ATCCTGCCGG AGGCCGAGGC GCGCCTGGGC CAGGCGGGCT TCATGCAGCG CCAGTTCGGG 
GCCATGCTCC AGCCCGGGGT CAACAAATTC TCGCTGCGGA TGTTCGGCAG CCAGAAAGCC 
GTGGAGCGCG AGCAGGAGAG GGTGAAGTCG GCCGGCTTCT GGATCATCCA CCCCTACAGC 
GACTTCAGGT TCTACTGGGA CCTGACCATG CTGCTGCTGA TGGTGGGGAA CCTGATCATC 
ATCCCCGTGG GCATCACCTT CTTCAAGGAC GAGAACACCA CGCCCTGGAT CGTGTTCAAC 
GTGGTGTCCG ACACCTTCTT CCTCATCGAC CTTGTCCTCA ACTTCCGCAC GGGCATTGTG 
GTGGAGGACA ACACGGACAT CATCCTGGAC CCGCGGCGCA TCAAGATGAA GTACCTGAAG 
AGCTGGTTCG TGGTGGACTT CGTGTCCTCC ATCCCCGTGG ACTACATCTT CCTCATCGTG 
GAGACGCGCA TCGACTCCGA GGTCTACAAG ACGGCCCGCG CCCTGCGCAT CGTGCGCTTC 
ACCAAGATCC TCAGCCTCCT GCGCCTGCTG CGGCTCTCAC GGCTCATCCG CTACATCCAC 
CAGTGGGAGG AGATCTTCCA CATGACCTAC GACCTGGCGA GCGCCGTGGT GCGCATCGTG 
AACCTCATCG GCATGATGCT GCTGCTGTGC CACTGGGACG GCTGCCTGCA GTTCCTGGTG 
CCCATGCTGC AGGACTTCCC TGACGACTGC TGGGTGTCCC TCAACAACAT GGTGAACAAC 
TCCTGGGGGA AGCAGTACTC CTACGCGCTC TTCAAGGCCA TGAGCCACAT GCTGTGCATC 
GGCTACGGGC GGCAGGCGCC CATGGGCATG TCCGACGTGT GGCTCACCAT GCTCAGCATG 
ATTGTGGGCG CCACCTGCTA CGCCATGTTC ATCGGCCACG CCACCGCGCT CATCCAGTCC 
CTGGACTCCT CCCGGCGCCA GTACCAGGAG AAGTACAAGC AGGTGGAGCA GTACATGTCC 
TTCCACAAGC TCCCGCCCGA CACCCGCCAG CGCATCCACG ACTACTACGA GCACCGGTAC 
CAGGGCAAGA TGTTCGACGA GGAGAGCATC CTGGGCGAGC TGAGCGAGCC GCTGCGGGAG 
GAGATCATCA ACTTCAACTG CCGCAAGCTG GTGGCCTCCA TGCCGCTGTT CGCCAACGCC 
GACCCCAACT TCGTGACGTC CATGCTGACC AAGCTGCGCT TCGAGGTCTT CCAGCCCGGG 
GACTACATCA TCCGCGAGGG CACCATCGGC AAGAAGATGT ACTTCATCCA GCACGGCGTG 
GTCAGCGTGC TCACCAAGGG CAACAAGGAG ACCAAGCTGG CCGACGGCTC CTACTTCGGA 
GAGATCTGCC TGCTGACCCG GGGCCGGCGC ACGGCCAGCG TGCGGGCCGA CACCTACTGC 
CGCCTCTACT CGCTGAGCGT GGACAACTTC AACGAGGTGC TGGAGGAGTA CCCCATGATG 
CGGCGCGCCT TCGAGACGGT GGCGCTGGAC CGGCTGGACC GCATCGGCAA GAAGAACTCG 
ATCCTCCTGC ACAAGGTGCA GCACGACCTG AGCTCGGGGG TCTCCAACTA CCAGGAGAAC 
GCCATCGTGC AGCGCATTGT GCAGCACGAC CGGGAGATGG CGCACTGCGC CCGCCGCGCC 
CAGGCCACCA CGCCCGTCGC GCCGGCCATC TGGACCCCGC TGATCCAGGC GCCACTGCAG 
GCAGCTGCCG CCACCACGTC AGTGGCCATC GCGCTCACCC ACCACCCTCG CCTGCCCGCG 
GCCATCTTCC GCCCGCCGCC CGGGCCCACC ACGCTCGGCT CGCTGGGCGC CGGGCAGACG 
CCGAGGCACC TGCGGCGCCT GCAGTCGCTG GCGCCGTCGG CGCCCAGCCC GGCCTCTCCG 
GCCAGCAGCC CATCGCAGCC GGACACGCCG TCCTCCGCCT CCCTGCACGT CCAGCCGCTG 
CCCGGCTGCT CCACGCCCGC TGGGCTCGGC TCCCTCCTGC CCACGGCCGG CTCGCCCCCG 
GCCCCCACAC CCCCCACCAC CGCTGGCGCC GCCGGCTTCA GCCACTTCCA CCGGGCGCTG 
GGCGGCTCCC TGTCCTCGTC CGACTCGCCC CTGCTCACCC CGATGCAGTC CGCTGCCCGC 
TCCCCGCAGC AGCCTCCCCC GCCGCCCGGG GCCCCGGCGG GCCTGGGCCT CCTGGAGCAC 
TTTCTGCCGC CTCCGGCCCG CTCCCCGACG TCCAGCCCGG GGCAGCTGGG CCAGCCCCCC 
GGGGAGCTGT CCCCAGGCCT GGGCTCCGGG CCTCCGGGCA CGCCAGAGAC GCCCCCGCGG 
CAGCCTGAGC GACTGCCCTT CGCGGCAGGG GCCTCTGCGG GGGCTTCCCC GGTGGCCTTC 
AGCCCCCGAG GCGGCCCCAG CCCCCCCGGC CACAGCCCGG GCACCCCAAG AACTTTCCCC 
AGCGCGCCGC CCCGGGCCTC GGGCTCGCAC GGGTCCCTGC TGCTGCCGCC GGCGTCCAGC 
CCGCCGCCGC CGCCGCCGCC GCCCGCCCCG CAGCGCCGCG CCACGCCGCC GCTGGCCCCC 
GGCCGCCTCT CGCAGGACCT CAAGCTCATC TCGGCCTCGC AGCCGGCGCT GCCCCAGGAC 
GGGGCGCAGA CTCTCCGCAG AGCCTCCCCG CACTCGTCCT CGGGGGAGTC GGTGGCCGCC 
CTGCCGCCCT TCCCCAGGGC CCCCGGGAGG CCCCCAGGCG CCGGCCCCGG CCAGCACGTC 
ACCCTCACTC TGCCTCGGAA GGCATCCTCA GGGTCTCTGC CGCCCCCTCT TTCTTTGTTC 
GGGCCGCGAG CCGCCCCTGC CGGGGGACCC CGGCTGACTG CGGCACCCCA GAGGGAACCA 
GGGGCCAAGT CTGAGCCAGT GCGCTCCAAA CTGCCGTCCA ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076176.1
CDS	122..3649
Translation	MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPRRRSIRLRPLPSPSPSPSAAAAAAGGAESRGAALGGAADGEGPARGAAKSSTNGDCRRFRGSLASLGSRGGGGGGGSTGGGSHGHLHDSAEERRLIAEGDASPGEDRTPPGLAAEPERPGAPAPPAASPPQVPSSCGEQRPADAAVKVEGGAAAGDQILPEAEARLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTDIILDPRRIKMKYLKSWFVVDFVSSIPVDYIFLIVETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSLNNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPMGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLSSGVSNYQENAIVQRIVQHDREMAHCARRAQATTPVAPAIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPTTLGSLGAGQTPRHLRRLQSLAPSAPSPASPASSPSQPDTPSSASLHVQPLPGCSTPAGLGSLLPTAGSPPAPTPPTTAGAAGFSHFHRALGGSLSSSDSPLLTPMQSAARSPQQPPPPPGAPAGLGLLEHFLPPPARSPTSSPGQLGQPPGELSPGLGSGPPGTPETPPRQPERLPFAAGASAGASPVAFSPRGGPSPPGHSPGTPRTFPSAPPRASGSHGSLLLPPASSPPPPPPPPAPQRRATPPLAPGRLSQDLKLISASQPALPQDGAQTLRRASPHSSSGESVAALPPFPRAPGRPPGAGPGQHVTLTLPRKASSGSLPPPLSLFGPRAAPAGGPRLTAAPQREPGAKSEPVRSKLPSNL

Target ORF information:

RefSeq Version	NM_001082707.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus hyperpolarization activated cyclic nucleotide gated potassium channel 4 (HCN4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082707.1

ORF Insert Sequence:

ATGGACAAGC TGCCGCCGTC CATGCGCAAG CGGCTGTACA GCCTCCCGCA GCAGGTGGGG 
GCCAAGGCGT GGATCATGGA CGAGGAGGAG GACGCCGAAG AAGAGGGCGC CGGGGGCCGC 
CAGGATCCCC GCCGCAGGAG CATCCGGCTG CGGCCGCTGC CCTCGCCCTC GCCCTCGCCC 
TCCGCGGCGG CGGCGGCGGC GGGCGGCGCG GAGTCCCGGG GCGCGGCCCT CGGAGGGGCG 
GCGGACGGCG AGGGGCCGGC CCGGGGCGCG GCCAAGTCCA GCACGAACGG CGACTGCAGG 
CGCTTCCGCG GGAGCCTGGC CTCGCTGGGC AGCCGTGGCG GCGGCGGCGG CGGCGGCAGC 
ACGGGCGGCG GCAGCCACGG GCACCTGCAT GACTCCGCCG AAGAGCGGCG GCTCATCGCC 
GAGGGCGACG CGTCCCCCGG CGAGGACAGG ACGCCCCCGG GCCTGGCGGC CGAGCCGGAG 
CGCCCGGGAG CCCCGGCGCC GCCCGCAGCC TCGCCGCCGC AGGTGCCCTC GTCCTGCGGC 
GAGCAGCGCC CGGCCGACGC GGCTGTCAAA GTGGAGGGAG GCGCGGCCGC GGGCGACCAG 
ATCCTGCCGG AGGCCGAGGC GCGCCTGGGC CAGGCGGGCT TCATGCAGCG CCAGTTCGGG 
GCCATGCTCC AGCCCGGGGT CAACAAATTC TCGCTGCGGA TGTTCGGCAG CCAGAAAGCC 
GTGGAGCGCG AGCAGGAGAG GGTGAAGTCG GCCGGCTTCT GGATCATCCA CCCCTACAGC 
GACTTCAGGT TCTACTGGGA CCTGACCATG CTGCTGCTGA TGGTGGGGAA CCTGATCATC 
ATCCCCGTGG GCATCACCTT CTTCAAGGAC GAGAACACCA CGCCCTGGAT CGTGTTCAAC 
GTGGTGTCCG ACACCTTCTT CCTCATCGAC CTTGTCCTCA ACTTCCGCAC GGGCATTGTG 
GTGGAGGACA ACACGGACAT CATCCTGGAC CCGCGGCGCA TCAAGATGAA GTACCTGAAG 
AGCTGGTTCG TGGTGGACTT CGTGTCCTCC ATCCCCGTGG ACTACATCTT CCTCATCGTG 
GAGACGCGCA TCGACTCCGA GGTCTACAAG ACGGCCCGCG CCCTGCGCAT CGTGCGCTTC 
ACCAAGATCC TCAGCCTCCT GCGCCTGCTG CGGCTCTCAC GGCTCATCCG CTACATCCAC 
CAGTGGGAGG AGATCTTCCA CATGACCTAC GACCTGGCGA GCGCCGTGGT GCGCATCGTG 
AACCTCATCG GCATGATGCT GCTGCTGTGC CACTGGGACG GCTGCCTGCA GTTCCTGGTG 
CCCATGCTGC AGGACTTCCC TGACGACTGC TGGGTGTCCC TCAACAACAT GGTGAACAAC 
TCCTGGGGGA AGCAGTACTC CTACGCGCTC TTCAAGGCCA TGAGCCACAT GCTGTGCATC 
GGCTACGGGC GGCAGGCGCC CATGGGCATG TCCGACGTGT GGCTCACCAT GCTCAGCATG 
ATTGTGGGCG CCACCTGCTA CGCCATGTTC ATCGGCCACG CCACCGCGCT CATCCAGTCC 
CTGGACTCCT CCCGGCGCCA GTACCAGGAG AAGTACAAGC AGGTGGAGCA GTACATGTCC 
TTCCACAAGC TCCCGCCCGA CACCCGCCAG CGCATCCACG ACTACTACGA GCACCGGTAC 
CAGGGCAAGA TGTTCGACGA GGAGAGCATC CTGGGCGAGC TGAGCGAGCC GCTGCGGGAG 
GAGATCATCA ACTTCAACTG CCGCAAGCTG GTGGCCTCCA TGCCGCTGTT CGCCAACGCC 
GACCCCAACT TCGTGACGTC CATGCTGACC AAGCTGCGCT TCGAGGTCTT CCAGCCCGGG 
GACTACATCA TCCGCGAGGG CACCATCGGC AAGAAGATGT ACTTCATCCA GCACGGCGTG 
GTCAGCGTGC TCACCAAGGG CAACAAGGAG ACCAAGCTGG CCGACGGCTC CTACTTCGGA 
GAGATCTGCC TGCTGACCCG GGGCCGGCGC ACGGCCAGCG TGCGGGCCGA CACCTACTGC 
CGCCTCTACT CGCTGAGCGT GGACAACTTC AACGAGGTGC TGGAGGAGTA CCCCATGATG 
CGGCGCGCCT TCGAGACGGT GGCGCTGGAC CGGCTGGACC GCATCGGCAA GAAGAACTCG 
ATCCTCCTGC ACAAGGTGCA GCACGACCTG AGCTCGGGGG TCTCCAACTA CCAGGAGAAC 
GCCATCGTGC AGCGCATTGT GCAGCACGAC CGGGAGATGG CGCACTGCGC CCGCCGCGCC 
CAGGCCACCA CGCCCGTCGC GCCGGCCATC TGGACCCCGC TGATCCAGGC GCCACTGCAG 
GCAGCTGCCG CCACCACGTC AGTGGCCATC GCGCTCACCC ACCACCCTCG CCTGCCCGCG 
GCCATCTTCC GCCCGCCGCC CGGGCCCACC ACGCTCGGCT CGCTGGGCGC CGGGCAGACG 
CCGAGGCACC TGCGGCGCCT GCAGTCGCTG GCGCCGTCGG CGCCCAGCCC GGCCTCTCCG 
GCCAGCAGCC CATCGCAGCC GGACACGCCG TCCTCCGCCT CCCTGCACGT CCAGCCGCTG 
CCCGGCTGCT CCACGCCCGC TGGGCTCGGC TCCCTCCTGC CCACGGCCGG CTCGCCCCCG 
GCCCCCACAC CCCCCACCAC CGCTGGCGCC GCCGGCTTCA GCCACTTCCA CCGGGCGCTG 
GGCGGCTCCC TGTCCTCGTC CGACTCGCCC CTGCTCACCC CGATGCAGTC CGCTGCCCGC 
TCCCCGCAGC AGCCTCCCCC GCCGCCCGGG GCCCCGGCGG GCCTGGGCCT CCTGGAGCAC 
TTTCTGCCGC CTCCGGCCCG CTCCCCGACG TCCAGCCCGG GGCAGCTGGG CCAGCCCCCC 
GGGGAGCTGT CCCCAGGCCT GGGCTCCGGG CCTCCGGGCA CGCCAGAGAC GCCCCCGCGG 
CAGCCTGAGC GACTGCCCTT CGCGGCAGGG GCCTCTGCGG GGGCTTCCCC GGTGGCCTTC 
AGCCCCCGAG GCGGCCCCAG CCCCCCCGGC CACAGCCCGG GCACCCCAAG AACTTTCCCC 
AGCGCGCCGC CCCGGGCCTC GGGCTCGCAC GGGTCCCTGC TGCTGCCGCC GGCGTCCAGC 
CCGCCGCCGC CGCCGCCGCC GCCCGCCCCG CAGCGCCGCG CCACGCCGCC GCTGGCCCCC 
GGCCGCCTCT CGCAGGACCT CAAGCTCATC TCGGCCTCGC AGCCGGCGCT GCCCCAGGAC 
GGGGCGCAGA CTCTCCGCAG AGCCTCCCCG CACTCGTCCT CGGGGGAGTC GGTGGCCGCC 
CTGCCGCCCT TCCCCAGGGC CCCCGGGAGG CCCCCAGGCG CCGGCCCCGG CCAGCACGTC 
ACCCTCACTC TGCCTCGGAA GGCATCCTCA GGGTCTCTGC CGCCCCCTCT TTCTTTGTTC 
GGGCCGCGAG CCGCCCCTGC CGGGGGACCC CGGCTGACTG CGGCACCCCA GAGGGAACCA 
GGGGCCAAGT CTGAGCCAGT GCGCTCCAAA CTGCCGTCCA ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HCN4-Overexpressing Mouse Embryonic Stem Cell-Derived Cardiomyocytes Generate a New Rapid Rhythm in Rats with Bradycardia.
International heart journal59(3)601-606(2018 May)
Saito Y,Nakamura K,Yoshida M,Sugiyama H,Takano M,Nagase S,Morita H,Kusano KF,Ito H

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.
Journal of molecular and cellular cardiology47(2)221-7(2009 Aug)
Brioschi C,Micheloni S,Tellez JO,Pisoni G,Longhi R,Moroni P,Billeter R,Barbuti A,Dobrzynski H,Boyett MR,DiFrancesco D,Baruscotti M

[Experimental study on influence of ischemia-reperfusion on expression of hyperpolarization activated cyclic nucleotide gated cation channel 4 of sinoatrial node cells in rabbits in vivo].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery23(7)856-60(2009 Jul)
Fu Y,Liao B,Yu F,Deng M,Feng Z,Zhan F,Li X,Wan J

In situ co-distribution and functional interactions of SAP97 with sinoatrial isoforms of HCN channels.
Journal of molecular and cellular cardiology46(5)636-43(2009 May)
Peters CJ,Chow SS,Angoli D,Nazzari H,Cayabyab FS,Morshedian A,Accili EA

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues.
Circulation research85(1)e1-6(1999 Jul)
Shi W,Wymore R,Yu H,Wu J,Wymore RT,Pan Z,Robinson RB,Dixon JE,McKinnon D,Cohen IS

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HCN4 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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