| Gene Symbol | INS |
| Entrez Gene ID | 100009181 |
| Full Name | insulin |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
IVD Raw Materials
ORF » Species Summary » Oryctolagus cuniculus » INS cDNA ORF clone
| Gene Symbol | INS |
| Entrez Gene ID | 100009181 |
| Full Name | insulin |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
| mRNA | Protein | Name |
|---|---|---|
| XM_017340618.1 | XP_017196107.1 | insulin isoform X1 |
| NM_001367056.1 | NP_001353985.1 | insulin precursor |
| NM_001082335.1 | NP_001075804.1 | insulin precursor |
Gastrulation in rabbit blastocysts depends on insulin and insulin-like-growth-factor 1.
Thieme R, Ramin N, Fischer S, Püschel B, Fischer B, Santos AN
Molecular and cellular endocrinology348(1)112-9(2012 Jan)
Maternal diabetes impairs gastrulation and insulin and IGF-I receptor expression in rabbit blastocysts.
Ramin N, Thieme R, Fischer S, Schindler M, Schmidt T, Fischer B, Navarrete Santos A
Endocrinology151(9)4158-67(2010 Sep)
Insulin gene expression and insulin synthesis in mammalian neuronal cells.
Devaskar SU, Giddings SJ, Rajakumar PA, Carnaghi LR, Menon RK, Zahm DS
The Journal of biological chemistry269(11)8445-54(1994 Mar)
Species variation in the amino acid sequence of insulin.
Smith LF
The American journal of medicine40(5)662-6(1966 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following INS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OOb30868 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082335.1 | |
| Accession Version | NM_001082335.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1509206400000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | insulin precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U03610.1. ##Evidence-Data-START## Transcript exon combination :: U03610.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03328770, SAMN03328771 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCCC TGGCCGCGCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001075804.1 |
| CDS | 17..349 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001082335.1 |
1 | ATGGCCTCCC TGGCCGCGCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb41888 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001367056.1 | |
| Accession Version | NM_001367056.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1577635200000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | insulin precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DP001064.1. On Nov 3, 2018 this sequence version replaced NM_001082335.1. ##Evidence-Data-START## Transcript exon combination :: U03610.1, M61153.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03328770, SAMN03328771 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCTCCCT GGCCGCGCCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001353985.1 |
| CDS | 17..349 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001367056.1 |
1 | ATGGCTCCCT GGCCGCGCCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb34056 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017340618.1 | |
| Accession Version | XM_017340618.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 417bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1466524800000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | insulin isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003161515.1) and transcript sequence (NM_001082335.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 34 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## | |
1 | ATGGCCTCCC TGGCCGCGCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017196107.1 |
| CDS | 17..433 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017340618.1 |
1 | ATGGCCTCCC TGGCCGCGCT CCTGCCCCTG CTGGCCCTGC TGGTCCTCTG CAGACTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gastrulation in rabbit blastocysts depends on insulin and insulin-like-growth-factor 1. |
Maternal diabetes impairs gastrulation and insulin and IGF-I receptor expression in rabbit blastocysts. |
Insulin gene expression and insulin synthesis in mammalian neuronal cells. |
Species variation in the amino acid sequence of insulin. |