| Gene Symbol | AGXT |
| Entrez Gene ID | 100009147 |
| Full Name | alanine-glyoxylate aminotransferase |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
IVD Raw Materials
ORF » Species Summary » Oryctolagus cuniculus » AGXT cDNA ORF clone
| Gene Symbol | AGXT |
| Entrez Gene ID | 100009147 |
| Full Name | alanine-glyoxylate aminotransferase |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001082309.1 | NP_001075778.1 | serine--pyruvate aminotransferase |
Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.
Motley A, Lumb MJ, Oatey PB, Jennings PR, De Zoysa PA, Wanders RJ, Tabak HF, Danpure CJ
The Journal of cell biology131(1)95-109(1995 Oct)
Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the marmoset and rabbit genes.
Purdue PE, Lumb MJ, Danpure CJ
European journal of biochemistry207(2)757-66(1992 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following AGXT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AGXT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OOb00288 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082309.1 | |
| Accession Version | NM_001082309.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1550246400000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | serine--pyruvate aminotransferase | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M84647.1. ##Evidence-Data-START## Transcript exon combination :: M84647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013641, SAMN00013645 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCCC GCCAGCTGCT GGTGGCGCCC CCGGAGGCTC TGCGCAAGCC CCTCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001075778.1 |
| CDS | 123..1301 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001082309.1 |
1 | ATGGCCTCCC GCCAGCTGCT GGTGGCGCCC CCGGAGGCTC TGCGCAAGCC CCTCTGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1. |
Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the marmoset and rabbit genes. |