ABCB1 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABCB1
Entrez Gene ID	100008914
Full Name	ATP binding cassette subfamily B member 1
Synonyms	ABC20,Abcb4,GP170,MDR1,P-GP,PGY1
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017344296.1	XP_017199785.1	multidrug resistance protein 1 isoform X2
NM_001082159.1	NP_001075628.1	multidrug resistance protein 1
XM_008261791.2	XP_008260013.1	multidrug resistance protein 1 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

The effect of pomelo mix ethyl acetate extract on CYP3A6 and P-glycoprotein gene transcripts in rabbits.
Irshaid YM, Zihlef MA, Zmeili SM, Al-Antary ET, Zmaily MG, Al-Embideen SN, Amireh AO
Drug metabolism letters7(2)137-40(2014 Jul)

Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies.
Verstraelen J, Reichl S
International journal of pharmaceutics441(1-2)765-75(2013 Jan)

Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.
Majumdar S, Hippalgaonkar K, Srirangam R
Drug metabolism and disposition: the biological fate of chemicals37(8)1718-25(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ABCB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OOb34778	XM_017344296.1 Latest version!	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OOb30930	NM_001082159.1 Latest version!	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OOb10927	XM_008261791.2 Latest version!	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABCB1 ( XM_017344296.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> XP_017199785.1 Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OOb34778
Clone ID Related Accession (Same CDS sequence)	XM_017344296.1
Accession Version	XM_017344296.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466524800000
Organism	Oryctolagus cuniculus(rabbit)
Product	multidrug resistance protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013678.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTCA AGTCCATGCT GAGACAGGAT GTGAGCTGGT TCGATGACCC TAAAAACACA 
ACTGGAGCGT TGACCACCAG GCTTGCCAAT GACGCTGCTC AGGTCAAAGG GGCGACTGGT 
TCCAGGCTTG CTGTAATTGC TCAGAACATA GCTAATCTTG GGACAGGAAT TATTATATCC 
TTAGTCTATG GTTGGCAGTT AACACTTCTG CTCTTAGCAA TTGTACCCAT CATCGCAATA 
GCTGGAGTTG TTGAAATGAA AATGTTGTCT GGGCAGGCAC TAAAAGATAA GAAAGAACTG 
GAAGGTTCCG GAAAGATTGC CACAGAAGCA ATAGAGAACT TCCGAACAGT CGTGTCTCTG 
ACTCGTGAGC AGAAGTTTGA AAATATGTAT GCGCAGAGTT TGCAGGTGCC ATACAGAAAC 
TCCTTGAAGA AAGCACACAT CTTTGGAATC ACATTCTCCT TCACCCAGGC CATGATGTAT 
TTTTCCTATG CTGGCTGTTT CCGATTTGGT GCCTTCCTGG TGGCACGGGA ACTGATGAGC 
TTCGAAAATG TTCTGTTGGT CTTTTCAGCA GTCGTCTTTG GTGCCATGGC GGTCGGGCAG 
GTCAGCTCAT TTGCCCCTGA CTATGCCAAA GCCAAGATCT CGGCTTCCCA CATCATCATG 
ATCCTTGAGA AACTCCCAAA GATTGACAGC TACAGCACGG AGGGCCTCAA GCTAGGTACG 
TTGGAAGGTA ATATGACCTT TAAGGATGTT GTGTTCAACT ATCCCACCCG ACCCGACATC 
CCAGTGCTGC AGGGGCTGAA CCTGCAGGTG AAGAAGGGCC AGACGCTGGC CCTGGTGGGC 
CCCAGTGGCT GCGGCAAGAG CACCGTGGTG CAGCTCATTG AGCGGTTCTA CGACCCCTTG 
GCCGGAACAG TGCTATTGGA TGGCAAAGAA GTAAATCAAC TGAATGTGCA GTGGCTGCGA 
GCCCACCTGG GAATTGTGTC CCAGGAGCCC ATCCTGTTTG ACTGCAGCAT CGCCGAGAAC 
ATCGCCTATG GAGACAATAG CCGGGTGGTG TCCCAGGACG AGATCATTAA GGCAGCCAAA 
GAGGCCAACA TCCACGCCTT CATCGACTCC TTGCCTGACA AATACAACAC CAGGGTGGGA 
GACAAGGGAA CCCAGCTCTC CGGCGGCCAG AAGCAGCGGA TTGCCATCGC CCGCGCCCTC 
GTGCGGCAGC CGCACATCCT GCTTCTGGAC GAAGCCACGT CGGCTCTGGA TACAGAAAGT 
GAGAAGGTGG TCCAAGAAGC CCTGGACAAG GCCCGGGAGG GCCGCACCTG CGTCGTGATC 
GCGCACCGCC TGTCCACCAT CCAGAACGCA GACATGATAG TGGTGTTCCA AAACGGCAGA 
GTCAAAGAGT GCGGCACTCA CCACCAGCTG CTGGCACAGA AAGGCATCTA CTTCTCCATG 
GTCAGTGTCC AGGCTGGAGG AAAGCGCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017199785.1
CDS	159..1631
Translation	MVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIAQNIANLGTGIIISLVYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQVPYRNSLKKAHIFGITFSFTQAMMYFSYAGCFRFGAFLVARELMSFENVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISASHIIMILEKLPKIDSYSTEGLKLGTLEGNMTFKDVVFNYPTRPDIPVLQGLNLQVKKGQTLALVGPSGCGKSTVVQLIERFYDPLAGTVLLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIIKAAKEANIHAFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADMIVVFQNGRVKECGTHHQLLAQKGIYFSMVSVQAGGKRQ

Target ORF information:

RefSeq Version	XM_017344296.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017344296.1

ORF Insert Sequence:

ATGGTGTTCA AGTCCATGCT GAGACAGGAT GTGAGCTGGT TCGATGACCC TAAAAACACA 
ACTGGAGCGT TGACCACCAG GCTTGCCAAT GACGCTGCTC AGGTCAAAGG GGCGACTGGT 
TCCAGGCTTG CTGTAATTGC TCAGAACATA GCTAATCTTG GGACAGGAAT TATTATATCC 
TTAGTCTATG GTTGGCAGTT AACACTTCTG CTCTTAGCAA TTGTACCCAT CATCGCAATA 
GCTGGAGTTG TTGAAATGAA AATGTTGTCT GGGCAGGCAC TAAAAGATAA GAAAGAACTG 
GAAGGTTCCG GAAAGATTGC CACAGAAGCA ATAGAGAACT TCCGAACAGT CGTGTCTCTG 
ACTCGTGAGC AGAAGTTTGA AAATATGTAT GCGCAGAGTT TGCAGGTGCC ATACAGAAAC 
TCCTTGAAGA AAGCACACAT CTTTGGAATC ACATTCTCCT TCACCCAGGC CATGATGTAT 
TTTTCCTATG CTGGCTGTTT CCGATTTGGT GCCTTCCTGG TGGCACGGGA ACTGATGAGC 
TTCGAAAATG TTCTGTTGGT CTTTTCAGCA GTCGTCTTTG GTGCCATGGC GGTCGGGCAG 
GTCAGCTCAT TTGCCCCTGA CTATGCCAAA GCCAAGATCT CGGCTTCCCA CATCATCATG 
ATCCTTGAGA AACTCCCAAA GATTGACAGC TACAGCACGG AGGGCCTCAA GCTAGGTACG 
TTGGAAGGTA ATATGACCTT TAAGGATGTT GTGTTCAACT ATCCCACCCG ACCCGACATC 
CCAGTGCTGC AGGGGCTGAA CCTGCAGGTG AAGAAGGGCC AGACGCTGGC CCTGGTGGGC 
CCCAGTGGCT GCGGCAAGAG CACCGTGGTG CAGCTCATTG AGCGGTTCTA CGACCCCTTG 
GCCGGAACAG TGCTATTGGA TGGCAAAGAA GTAAATCAAC TGAATGTGCA GTGGCTGCGA 
GCCCACCTGG GAATTGTGTC CCAGGAGCCC ATCCTGTTTG ACTGCAGCAT CGCCGAGAAC 
ATCGCCTATG GAGACAATAG CCGGGTGGTG TCCCAGGACG AGATCATTAA GGCAGCCAAA 
GAGGCCAACA TCCACGCCTT CATCGACTCC TTGCCTGACA AATACAACAC CAGGGTGGGA 
GACAAGGGAA CCCAGCTCTC CGGCGGCCAG AAGCAGCGGA TTGCCATCGC CCGCGCCCTC 
GTGCGGCAGC CGCACATCCT GCTTCTGGAC GAAGCCACGT CGGCTCTGGA TACAGAAAGT 
GAGAAGGTGG TCCAAGAAGC CCTGGACAAG GCCCGGGAGG GCCGCACCTG CGTCGTGATC 
GCGCACCGCC TGTCCACCAT CCAGAACGCA GACATGATAG TGGTGTTCCA AAACGGCAGA 
GTCAAAGAGT GCGGCACTCA CCACCAGCTG CTGGCACAGA AAGGCATCTA CTTCTCCATG 
GTCAGTGTCC AGGCTGGAGG AAAGCGCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB1 ( NM_001082159.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001075628.1 Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), mRNA.

Price & Availability↑

CloneID	OOb30930
Clone ID Related Accession (Same CDS sequence)	NM_001082159.1
Accession Version	NM_001082159.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1488297600000
Organism	Oryctolagus cuniculus(rabbit)
Product	multidrug resistance protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY360144.3. ##Evidence-Data-START## Transcript exon combination :: AY360144.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013637, SAMN00013641 [ECO:0000348] ##Evidence-Data-END##

ATGGACATCG AGGGGGAACG CAATGGACGG CTCGGGAAGA ACATGTACAA GCTGAACAAG 
AGAAATAAAA AAGAAAAGGA AAAGAGACCA ACTGTCAGCG CATTTGCAAT GTTCCGCTAT 
TCAAATTGGC TTGATAAATT GTACATGGTG GTGGGGACCT TGGCTGCCAT CATCCATGGA 
GCTGCACTGC CCCTCATGAT GCTGGTGTTT GGAGACATGA CGGACAGCTT TTCAAACCCA 
GGAAATATGA TTCCAGCAAA CATCACTAAT CTTAACATGA GTAACATCAG CGCCTCTGAG 
ATCTACGAAC ATCTGGAGGA AGAAATGACC ACGTACGCCT ACTACTACAG TGGAATTGGT 
GCTGGTGTGC TTGTTGCTGC TTACATTCAG GTTTCGTTTT GGTGCTTGGC AGCTGGAAGA 
CAAACATTTA AAATTAGAAA ACAGTTTTTT CATTCTATAA TGCGCCAGGA GATAGGCTGG 
TTTGACGTGC ATGATGTTGG AGAGCTGAAC ACCCGGCTCA CAGATGATGT CTCCAAAATT 
AATGACGGGA TTGGTGACAA AATTGGAATG TTCTTTCAGT CAATGTCAAC ATTTTTCACC 
GGTTTTATAG TAGGATTTAC ACGTGGTTGG AAACTAACCC TTGTGATTTT GGCCATTAGT 
CCTGTTCTTG GACTCTCAGC TGCTCTCTGG GCAAAGATAA TGTCTTCATT TACTGATAAA 
GAACTGTTAG CGTATGCAAA AGCAGGAGCT GTGGCTGAAG AGGTCCTAGC GGCAATTAGA 
ACTGTGATTG CGTTTGGAGG ACAACAGAAG GAACTGGAAA GGTACAATAA AAATTTAGAA 
GAAGCTAAAA GAATTGGGAT AAAGAAAGCT ATTACAGCCA ACATCTCTGT GGGTGTTGCT 
TTCCTGCTGA TGTATGCATC GTATGCGCTG GCCTTCTGGT ATTGGAACCA CCTTGGTCAT 
CTCAAAGAAT ATTCTATCGG ACAAGTACTC ACTGTCTTCT TTTCTGTATT AGTTGGAGCT 
TTCAGTATTG GCCAAGCATC TCCAAATGTT GAAGCATTTG CAAATGCAAG AGGAGCAGCT 
TATGAAATCT TCAGGATCAT CGATAATATG CCGAGCATTG ACAGCTACTC GGAGGCCGGG 
CACAAACCAG ATAATATTAA AGGAAATTTG GAATTCAGAA ATGTTCATTT CAGCTACCCT 
TCTCGAAAAG AAGTTAAGAT CTTGAAGGGC CTCAACCTGA AGGTGGAGAG CGGGCAGACG 
GTGGCCCTGG TGGGGAACAG TGGCTGTGGG AAGAGCACGA CCGTCCAGCT GATGCGGAGA 
CTCTATGACC CCACGGACGG CGTGGTCAGC ATTGATGGCC AGGACATCAG AACCATGAAC 
GTGAGGTATC TGCGGGAAAT TACCGGCGTG GTGAGTCAGG AACCTGTGTT GTTCGCCACC 
ACAATCGCTG AGAACGTCCG CTATGGCCGA GAAGATGTCA CCATGGATGA GATTGAAAAG 
GCTGTCAAGG AAGCCAACGC CTACAACTTT ATCATGAAGC TACCTCATAA ATTCGACACT 
CTGGTTGGAG AGAGAGGGGC CCAGCTGAGC GGTGGGCAGA AACAGAGGAT CGCCATTGCC 
CGTGCCCTGG TTCGCAACCC CAAGATCCTC CTGCTGGACG AGGCCACCTC AGCCTTGGAC 
ACAGAAAGTG AAGCTGTGGT TCAGGTGGCT CTAGATAAGG CTAGAAAAGG CCGCACAACT 
ATTGTGATAG CTCACCGCCT GTCTACAGTT CGCAATGCTG ATGTCATTGC TGGATTTGAT 
AATGGAGTCA TTGTGGAGAG AGGAAATCAT GAGGAACTCA TGAGGCAGAA AGGCGTTTAC 
TTCAGACTTG TCACAATGCA GACAGCAGGA AATGAAATTG ACTTAGAAAA TTCAGCTAGT 
GAATCTAGAG GTGAAAAAAT GGATTTGGTG GAAATGTCTG CTAAAGAGTC AGGATCCAGT 
CTGATAAGAA GGAGATCAAG TCACAAGAGT TTTCATGGAG CTCAAGGCCA AGATGGGAAG 
CTTAGCACTA CAGAGGCCCA GAATGAAAAT GTACCTCCAG TTTCCTTTTG GAGAATTATG 
AAGCTGAATT TAACTGAATG GCCTTATTTT TTGGTGGGTG TAATTTGTGC CATTATAAAT 
GGAGGCCTAC AACCAGCATT TGCAGTAGTA TTTTCAAAGA TTGTGGGAGT TTTCACAAGA 
AATGATGATG ATGAAACAAA ACGGCGGAAT AGTGACCTGT TTTCCTTGTT GTTCCTCATC 
CTTGGAATTA TTTCCTTTAT TACATTTTTC CTTCAGGGCT TCACCTTTGG CAAAGCCGGG 
GAAATCCTCA CCAAGCGCCT GCGCTACATG GTGTTCAAGT CCATGCTGAG ACAGGATGTG 
AGCTGGTTTG ATGACCCTAA AAACACAACT GGAGCGTTGA CCACCAGGCT TGCCAATGAC 
GCTGCTCAGG TCAAAGGGGC GACTGGTTCC AGGCTTGCTG TAATTGCTCA GAACATAGCT 
AATCTTGGGA CAGGAATTAT TATATCCTTA GTCTATGGTT GGCAGTTAAC ACTTCTGCTC 
TTAGCAATTG TACCCATCAT CGCAATAGCT GGAGTTGTTG AAATGAAAAT GTTGTCTGGG 
CAGGCACTAA AAGATAAGAA AGAACTGGAA GGTTCCGGAA AGATTGCCAC AGAAGCAATA 
GAGAACTTCC GAACAGTCGT GTCTCTGACT CGTGAGCAGA AGTTTGAAAA TATGTATGCG 
CAGAGTTTGC AGGTGCCATA CAGAAACTCC TTGGAGAAAG CACACATCTT TGGAATCACA 
TTCTCCTTCA CCCAGGCCAT GATGTATTTT TCCTATGCTG GCTGTTTCCG ATTTGGTGCC 
TTCCTGGTGG CACGGGAACT GATGAGCTTC GAAAATGTTC TGTTGGTCTT TTCAGCAGTC 
GTCTTTGGTG CCATGGCGGT CGGGCAGGTC AGCTCATTTG CCCCTGACTA TGCCAAAGCC 
AAGATCTCGG CTTCCCACAT CATCATGATC CTTGAGAAAC TCCCAAAGAT TGACAGCTAC 
AGCACGGAGG GCCTCAAGCC AGGTACGTTG GAAGGTAATA TGACCTTTAA GGATGTTGTG 
TTCAACTATC CCACCCGACC CGACATCCCA GTGCTGCAGG GGCTGAACCT GCAGGTGAAG 
AAGGGCCAGA CGCTGGCCCT GGTGGGCCCC AGTGGCTGCG GCAAGAGCAC CGTGGTGCAG 
CTCATTGAGC GGTTCTACGA CCCCTTGGCC GGAACAGTGC TATTGGATGG CAAAGAAGTA 
AATCAACTGA ATGTGCAGTG GCTGCGAGCC CACCTGGGAA TTGTGTCCCA GGAGCCCATC 
CTGTTTGACT GCAGCATCGC CGAGAACATC GCCTACGGAG ACAATAGCCG GGTCGTGTCC 
CAGGACGAGA TCATTAAGGC AGCCAAGGAG GCCAACATCC ACGCCTTCAT CGACTCCTTG 
CCTGATAAAT ACAACACCAG GGTGGGAGAC AAGGGAACCC AGCTCTCCGG CGGCCAGAAG 
CAGCGGATTG CCATCGCCCG CGCCCTCGTG CGGCAGCCGC ACATCCTGCT TCTGGACGAA 
GCCACGTCGG CTCCGGATAC AGAAAGTGAG AAGGTGGTCC AAGAAGCCCT GGACAAGGCC 
CGGGAGGGCC GCACCTGCGT CGTGATCGCG CACCGCCTGT CCACCATCCA GAACGCAGAC 
ATGATAGTGG TGTTCCAAAA CGGCAGAGTC AAAGAGTGCG GCACTCACCA CCAGCTGCTG 
GCACAGAAAG GCATCTACTT CTCCATGGTC AGTGTCCAGG CTGGAGGAAA GCGCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001075628.1
CDS	144..3983
Translation	MDIEGERNGRLGKNMYKLNKRNKKEKEKRPTVSAFAMFRYSNWLDKLYMVVGTLAAIIHGAALPLMMLVFGDMTDSFSNPGNMIPANITNLNMSNISASEIYEHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQTFKIRKQFFHSIMRQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSMSTFFTGFIVGFTRGWKLTLVILAISPVLGLSAALWAKIMSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKRIGIKKAITANISVGVAFLLMYASYALAFWYWNHLGHLKEYSIGQVLTVFFSVLVGAFSIGQASPNVEAFANARGAAYEIFRIIDNMPSIDSYSEAGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVESGQTVALVGNSGCGKSTTVQLMRRLYDPTDGVVSIDGQDIRTMNVRYLREITGVVSQEPVLFATTIAENVRYGREDVTMDEIEKAVKEANAYNFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDNGVIVERGNHEELMRQKGVYFRLVTMQTAGNEIDLENSASESRGEKMDLVEMSAKESGSSLIRRRSSHKSFHGAQGQDGKLSTTEAQNENVPPVSFWRIMKLNLTEWPYFLVGVICAIINGGLQPAFAVVFSKIVGVFTRNDDDETKRRNSDLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIAQNIANLGTGIIISLVYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQVPYRNSLEKAHIFGITFSFTQAMMYFSYAGCFRFGAFLVARELMSFENVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISASHIIMILEKLPKIDSYSTEGLKPGTLEGNMTFKDVVFNYPTRPDIPVLQGLNLQVKKGQTLALVGPSGCGKSTVVQLIERFYDPLAGTVLLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIIKAAKEANIHAFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAPDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADMIVVFQNGRVKECGTHHQLLAQKGIYFSMVSVQAGGKRQ

Target ORF information:

RefSeq Version	NM_001082159.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082159.1

ORF Insert Sequence:

ATGGACATCG AGGGGGAACG CAATGGACGG CTCGGGAAGA ACATGTACAA GCTGAACAAG 
AGAAATAAAA AAGAAAAGGA AAAGAGACCA ACTGTCAGCG CATTTGCAAT GTTCCGCTAT 
TCAAATTGGC TTGATAAATT GTACATGGTG GTGGGGACCT TGGCTGCCAT CATCCATGGA 
GCTGCACTGC CCCTCATGAT GCTGGTGTTT GGAGACATGA CGGACAGCTT TTCAAACCCA 
GGAAATATGA TTCCAGCAAA CATCACTAAT CTTAACATGA GTAACATCAG CGCCTCTGAG 
ATCTACGAAC ATCTGGAGGA AGAAATGACC ACGTACGCCT ACTACTACAG TGGAATTGGT 
GCTGGTGTGC TTGTTGCTGC TTACATTCAG GTTTCGTTTT GGTGCTTGGC AGCTGGAAGA 
CAAACATTTA AAATTAGAAA ACAGTTTTTT CATTCTATAA TGCGCCAGGA GATAGGCTGG 
TTTGACGTGC ATGATGTTGG AGAGCTGAAC ACCCGGCTCA CAGATGATGT CTCCAAAATT 
AATGACGGGA TTGGTGACAA AATTGGAATG TTCTTTCAGT CAATGTCAAC ATTTTTCACC 
GGTTTTATAG TAGGATTTAC ACGTGGTTGG AAACTAACCC TTGTGATTTT GGCCATTAGT 
CCTGTTCTTG GACTCTCAGC TGCTCTCTGG GCAAAGATAA TGTCTTCATT TACTGATAAA 
GAACTGTTAG CGTATGCAAA AGCAGGAGCT GTGGCTGAAG AGGTCCTAGC GGCAATTAGA 
ACTGTGATTG CGTTTGGAGG ACAACAGAAG GAACTGGAAA GGTACAATAA AAATTTAGAA 
GAAGCTAAAA GAATTGGGAT AAAGAAAGCT ATTACAGCCA ACATCTCTGT GGGTGTTGCT 
TTCCTGCTGA TGTATGCATC GTATGCGCTG GCCTTCTGGT ATTGGAACCA CCTTGGTCAT 
CTCAAAGAAT ATTCTATCGG ACAAGTACTC ACTGTCTTCT TTTCTGTATT AGTTGGAGCT 
TTCAGTATTG GCCAAGCATC TCCAAATGTT GAAGCATTTG CAAATGCAAG AGGAGCAGCT 
TATGAAATCT TCAGGATCAT CGATAATATG CCGAGCATTG ACAGCTACTC GGAGGCCGGG 
CACAAACCAG ATAATATTAA AGGAAATTTG GAATTCAGAA ATGTTCATTT CAGCTACCCT 
TCTCGAAAAG AAGTTAAGAT CTTGAAGGGC CTCAACCTGA AGGTGGAGAG CGGGCAGACG 
GTGGCCCTGG TGGGGAACAG TGGCTGTGGG AAGAGCACGA CCGTCCAGCT GATGCGGAGA 
CTCTATGACC CCACGGACGG CGTGGTCAGC ATTGATGGCC AGGACATCAG AACCATGAAC 
GTGAGGTATC TGCGGGAAAT TACCGGCGTG GTGAGTCAGG AACCTGTGTT GTTCGCCACC 
ACAATCGCTG AGAACGTCCG CTATGGCCGA GAAGATGTCA CCATGGATGA GATTGAAAAG 
GCTGTCAAGG AAGCCAACGC CTACAACTTT ATCATGAAGC TACCTCATAA ATTCGACACT 
CTGGTTGGAG AGAGAGGGGC CCAGCTGAGC GGTGGGCAGA AACAGAGGAT CGCCATTGCC 
CGTGCCCTGG TTCGCAACCC CAAGATCCTC CTGCTGGACG AGGCCACCTC AGCCTTGGAC 
ACAGAAAGTG AAGCTGTGGT TCAGGTGGCT CTAGATAAGG CTAGAAAAGG CCGCACAACT 
ATTGTGATAG CTCACCGCCT GTCTACAGTT CGCAATGCTG ATGTCATTGC TGGATTTGAT 
AATGGAGTCA TTGTGGAGAG AGGAAATCAT GAGGAACTCA TGAGGCAGAA AGGCGTTTAC 
TTCAGACTTG TCACAATGCA GACAGCAGGA AATGAAATTG ACTTAGAAAA TTCAGCTAGT 
GAATCTAGAG GTGAAAAAAT GGATTTGGTG GAAATGTCTG CTAAAGAGTC AGGATCCAGT 
CTGATAAGAA GGAGATCAAG TCACAAGAGT TTTCATGGAG CTCAAGGCCA AGATGGGAAG 
CTTAGCACTA CAGAGGCCCA GAATGAAAAT GTACCTCCAG TTTCCTTTTG GAGAATTATG 
AAGCTGAATT TAACTGAATG GCCTTATTTT TTGGTGGGTG TAATTTGTGC CATTATAAAT 
GGAGGCCTAC AACCAGCATT TGCAGTAGTA TTTTCAAAGA TTGTGGGAGT TTTCACAAGA 
AATGATGATG ATGAAACAAA ACGGCGGAAT AGTGACCTGT TTTCCTTGTT GTTCCTCATC 
CTTGGAATTA TTTCCTTTAT TACATTTTTC CTTCAGGGCT TCACCTTTGG CAAAGCCGGG 
GAAATCCTCA CCAAGCGCCT GCGCTACATG GTGTTCAAGT CCATGCTGAG ACAGGATGTG 
AGCTGGTTTG ATGACCCTAA AAACACAACT GGAGCGTTGA CCACCAGGCT TGCCAATGAC 
GCTGCTCAGG TCAAAGGGGC GACTGGTTCC AGGCTTGCTG TAATTGCTCA GAACATAGCT 
AATCTTGGGA CAGGAATTAT TATATCCTTA GTCTATGGTT GGCAGTTAAC ACTTCTGCTC 
TTAGCAATTG TACCCATCAT CGCAATAGCT GGAGTTGTTG AAATGAAAAT GTTGTCTGGG 
CAGGCACTAA AAGATAAGAA AGAACTGGAA GGTTCCGGAA AGATTGCCAC AGAAGCAATA 
GAGAACTTCC GAACAGTCGT GTCTCTGACT CGTGAGCAGA AGTTTGAAAA TATGTATGCG 
CAGAGTTTGC AGGTGCCATA CAGAAACTCC TTGGAGAAAG CACACATCTT TGGAATCACA 
TTCTCCTTCA CCCAGGCCAT GATGTATTTT TCCTATGCTG GCTGTTTCCG ATTTGGTGCC 
TTCCTGGTGG CACGGGAACT GATGAGCTTC GAAAATGTTC TGTTGGTCTT TTCAGCAGTC 
GTCTTTGGTG CCATGGCGGT CGGGCAGGTC AGCTCATTTG CCCCTGACTA TGCCAAAGCC 
AAGATCTCGG CTTCCCACAT CATCATGATC CTTGAGAAAC TCCCAAAGAT TGACAGCTAC 
AGCACGGAGG GCCTCAAGCC AGGTACGTTG GAAGGTAATA TGACCTTTAA GGATGTTGTG 
TTCAACTATC CCACCCGACC CGACATCCCA GTGCTGCAGG GGCTGAACCT GCAGGTGAAG 
AAGGGCCAGA CGCTGGCCCT GGTGGGCCCC AGTGGCTGCG GCAAGAGCAC CGTGGTGCAG 
CTCATTGAGC GGTTCTACGA CCCCTTGGCC GGAACAGTGC TATTGGATGG CAAAGAAGTA 
AATCAACTGA ATGTGCAGTG GCTGCGAGCC CACCTGGGAA TTGTGTCCCA GGAGCCCATC 
CTGTTTGACT GCAGCATCGC CGAGAACATC GCCTACGGAG ACAATAGCCG GGTCGTGTCC 
CAGGACGAGA TCATTAAGGC AGCCAAGGAG GCCAACATCC ACGCCTTCAT CGACTCCTTG 
CCTGATAAAT ACAACACCAG GGTGGGAGAC AAGGGAACCC AGCTCTCCGG CGGCCAGAAG 
CAGCGGATTG CCATCGCCCG CGCCCTCGTG CGGCAGCCGC ACATCCTGCT TCTGGACGAA 
GCCACGTCGG CTCCGGATAC AGAAAGTGAG AAGGTGGTCC AAGAAGCCCT GGACAAGGCC 
CGGGAGGGCC GCACCTGCGT CGTGATCGCG CACCGCCTGT CCACCATCCA GAACGCAGAC 
ATGATAGTGG TGTTCCAAAA CGGCAGAGTC AAAGAGTGCG GCACTCACCA CCAGCTGCTG 
GCACAGAAAG GCATCTACTT CTCCATGGTC AGTGTCCAGG CTGGAGGAAA GCGCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCB1 ( XM_008261791.2 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> XP_008260013.1 Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X1, mRNA.

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CloneID	OOb10927
Clone ID Related Accession (Same CDS sequence)	XM_008261791.2
Accession Version	XM_008261791.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466524800000
Organism	Oryctolagus cuniculus(rabbit)
Product	multidrug resistance protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013678.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008261791.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATCG AAGGGGAACG CAATGGACGG CTCGGGAAGA ACATGTACAA GCTGAACAAG 
AGAAATAAAA AAGAAAAGGA AAAGAGACCA ACTGTCAGCG CATTTGCAAT GTTCCGCTAT 
TCAAATTGGC TTGATAAATT GTACATGGTG GTGGGGACCT TGGCTGCCAT CATCCATGGA 
GCTGCACTGC CCCTCATGAT GCTGGTGTTT GGAGACATGA CGGACAGCTT TTCAAACCCA 
GGAAATATGA TTCCAGCAAA CATCACTAAT CTTAACATGA GTAACATCAG CGCCTCTGAG 
ATCTACAAAC ATCTGGAGGA AGAAATGACC ACGTACGCCT ACTACTACAG TGGAATTGGT 
GCTGGTGTGC TTGTTGCTGC TTACATTCAG GTTTCGTTTT GGTGCTTGGC AGCTGGAAGA 
CAAACATTTA AAATTAGAAA ACAGTTTTTT CATTCCATAA TGCGCCAGGA GATAGGCTGG 
TTTGACGTGC ATGATGTTGG AGAGCTGAAC ACCCGGCTCA CAGATGATGT CTCCAAAATT 
AATGACGGGA TTGGTGACAA AATTGGAATG TTCTTTCAGT CAATGTCAAC ATTTTTCACC 
GGTTTTATAG TAGGATTTAC ACGTGGTTGG AAACTAACCC TGGTGATTTT GGCCATTAGT 
CCTGTTCTTG GACTCTCAGC TGCTCTCTGG GCAAAGATAA TGTCTTCATT TACTGATAAA 
GAACTGTTGG CGTATGCAAA AGCAGGAGCT GTGGCTGAAG AGGTCCTAGC GGCAATTAGA 
ACTGTGATTG CGTTTGGAGG ACAACAGAAG GAACTGGAAA GGTACAATAA AAATTTAGAA 
GAAGCTAAAA GAATTGGGAT AAAGAAAGCT ATTACAGCCA ACATCTCTGT GGGTGTTGCT 
TTCCTGCTGA TGTATGCATC GTATGCGCTG GCCTTCTGGT ATGGAACCAC CTTGGTCATC 
TCAAAAGAAT ATTCTATCGG ACAAGTGCTC ACTGTCTTCT TTTCTGTATT AGTTGGAGCT 
TTCAGTATTG GCCAAGCATC TCCAAATGTT GAAGCATTTG CAAATGCAAG AGGAGCAGCT 
TATGAAATCT TCAGGATCAT CGATAATAAG CCGAGCATTG ACAGCTACTC GGAGGCCGGG 
CACAAACCAG ATAATATTAA AGGAAATTTG GAATTCAGAA ATGTTCATTT CAGCTACCCT 
TCTCGAAAAG AAGTTAAGAT CTTGAAGGGC CTCAACCTGA AGGTGGAGAG CGGGCAGACG 
GTGGCCCTGG TGGGGAACAG TGGCTGTGGG AAGAGCACGA CCGTCCAGCT GATGCAGAGA 
CTCTATGACC CCACGGACGG CGTGGTCAGC ATTGATGGCC AGGACATCAG GACCATGAAC 
GTGAGGTATC TGCGGGAAAT TACCGGCGTG GTGAGTCAGG AACCTGTGTT GTTCGCCACC 
ACAATCGCTG AGAACATCCG CTATGGCCGA GAAGATGTCA CCATGGATGA GATTGAAAAG 
GCTGTCAAGG AAGCCAACGC CTACAACTTT ATCATGAAGC TACCTCATAA ATTCGACACT 
CTGGTTGGAG AGAGAGGGGC CCAGCTGAGC GGTGGGCAGA AACAGAGGAT CGCCATTGCC 
CGTGCCCTGG TTCGCAACCC CAAGATCCTC CTGCTGGACG AGGCCACCTC AGCCTTGGAC 
ACAGAAAGTG AAGCTGTGGT TCAGGTGGCT CTAGATAAGG CTAGAAAAGG CCGCACAACT 
ATTGTGATAG CTCACCGCCT GTCTACAGTT CGCAATGCTG ATGTCATTGC TGGATTTGAT 
AATGGAGTCA TTGTGGAGAG AGGAAATCAT GAGGAACTCA TGAGGCAGAA AGGCGTTTAC 
TTCAGACTTG TCACAATGCA GACAGCAGGA AATGAAATTG ACTTAGAAAA TTCAGCTAGT 
GAATCTAGAG GTGAAAAAAT GGATTTGGTG GAAATGTCTG CTAAAGAGTC AGGATCCAGT 
CTGATAAGAA GGAGATCAAG TCACAAGAGT TTTCATGGAG CTCAAGGCCA AGATGGGAAG 
CTTAGCACTA CAGAGGCCCA GAATGAAAAT GTACCTCCAG TTTCCTTTTG GAGAATTATG 
AAGCTGAATT TAACTGAATG GCCTTATTTT TTGGTGGGTG TAATTTGTGC CATTATAAAT 
GGAGGCCTAC AACCAGCATT TGCAGTAGTA TTTTCAAAGA TTGTGGGAGT TTTCACAAGA 
AATGATGATG ATGAAACAAA ACGGCGGAAT AGTGACCTGT TTTCCTTGTT GTTCCTCATC 
CTTGGAATTA TTTCCTTTAT TACATTTTTC CTTCAGGGCT TCACCTTTGG CAAAGCCGGG 
GAAATCCTCA CCAAGCGCCT GCGCTACATG GTGTTCAAGT CCATGCTGAG ACAGGATGTG 
AGCTGGTTCG ATGACCCTAA AAACACAACT GGAGCGTTGA CCACCAGGCT TGCCAATGAC 
GCTGCTCAGG TCAAAGGGGC GACTGGTTCC AGGCTTGCTG TAATTGCTCA GAACATAGCT 
AATCTTGGGA CAGGAATTAT TATATCCTTA GTCTATGGTT GGCAGTTAAC ACTTCTGCTC 
TTAGCAATTG TACCCATCAT CGCAATAGCT GGAGTTGTTG AAATGAAAAT GTTGTCTGGG 
CAGGCACTAA AAGATAAGAA AGAACTGGAA GGTTCCGGAA AGATTGCCAC AGAAGCAATA 
GAGAACTTCC GAACAGTCGT GTCTCTGACT CGTGAGCAGA AGTTTGAAAA TATGTATGCG 
CAGAGTTTGC AGGTGCCATA CAGAAACTCC TTGAAGAAAG CACACATCTT TGGAATCACA 
TTCTCCTTCA CCCAGGCCAT GATGTATTTT TCCTATGCTG GCTGTTTCCG ATTTGGTGCC 
TTCCTGGTGG CACGGGAACT GATGAGCTTC GAAAATGTTC TGTTGGTCTT TTCAGCAGTC 
GTCTTTGGTG CCATGGCGGT CGGGCAGGTC AGCTCATTTG CCCCTGACTA TGCCAAAGCC 
AAGATCTCGG CTTCCCACAT CATCATGATC CTTGAGAAAC TCCCAAAGAT TGACAGCTAC 
AGCACGGAGG GCCTCAAGCT AGGTACGTTG GAAGGTAATA TGACCTTTAA GGATGTTGTG 
TTCAACTATC CCACCCGACC CGACATCCCA GTGCTGCAGG GGCTGAACCT GCAGGTGAAG 
AAGGGCCAGA CGCTGGCCCT GGTGGGCCCC AGTGGCTGCG GCAAGAGCAC CGTGGTGCAG 
CTCATTGAGC GGTTCTACGA CCCCTTGGCC GGAACAGTGC TATTGGATGG CAAAGAAGTA 
AATCAACTGA ATGTGCAGTG GCTGCGAGCC CACCTGGGAA TTGTGTCCCA GGAGCCCATC 
CTGTTTGACT GCAGCATCGC CGAGAACATC GCCTATGGAG ACAATAGCCG GGTGGTGTCC 
CAGGACGAGA TCATTAAGGC AGCCAAAGAG GCCAACATCC ACGCCTTCAT CGACTCCTTG 
CCTGACAAAT ACAACACCAG GGTGGGAGAC AAGGGAACCC AGCTCTCCGG CGGCCAGAAG 
CAGCGGATTG CCATCGCCCG CGCCCTCGTG CGGCAGCCGC ACATCCTGCT TCTGGACGAA 
GCCACGTCGG CTCTGGATAC AGAAAGTGAG AAGGTGGTCC AAGAAGCCCT GGACAAGGCC 
CGGGAGGGCC GCACCTGCGT CGTGATCGCG CACCGCCTGT CCACCATCCA GAACGCAGAC 
ATGATAGTGG TGTTCCAAAA CGGCAGAGTC AAAGAGTGCG GCACTCACCA CCAGCTGCTG 
GCACAGAAAG GCATCTACTT CTCCATGGTC AGTGTCCAGG CTGGAGGAAA GCGCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008260013.1
CDS	207..4046
Translation	MDIEGERNGRLGKNMYKLNKRNKKEKEKRPTVSAFAMFRYSNWLDKLYMVVGTLAAIIHGAALPLMMLVFGDMTDSFSNPGNMIPANITNLNMSNISASEIYKHLEEEMTTYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQTFKIRKQFFHSIMRQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSMSTFFTGFIVGFTRGWKLTLVILAISPVLGLSAALWAKIMSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKRIGIKKAITANISVGVAFLLMYASYALAFWYGTTLVISKEYSIGQVLTVFFSVLVGAFSIGQASPNVEAFANARGAAYEIFRIIDNKPSIDSYSEAGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVESGQTVALVGNSGCGKSTTVQLMQRLYDPTDGVVSIDGQDIRTMNVRYLREITGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYNFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDNGVIVERGNHEELMRQKGVYFRLVTMQTAGNEIDLENSASESRGEKMDLVEMSAKESGSSLIRRRSSHKSFHGAQGQDGKLSTTEAQNENVPPVSFWRIMKLNLTEWPYFLVGVICAIINGGLQPAFAVVFSKIVGVFTRNDDDETKRRNSDLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIAQNIANLGTGIIISLVYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFENMYAQSLQVPYRNSLKKAHIFGITFSFTQAMMYFSYAGCFRFGAFLVARELMSFENVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISASHIIMILEKLPKIDSYSTEGLKLGTLEGNMTFKDVVFNYPTRPDIPVLQGLNLQVKKGQTLALVGPSGCGKSTVVQLIERFYDPLAGTVLLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIIKAAKEANIHAFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADMIVVFQNGRVKECGTHHQLLAQKGIYFSMVSVQAGGKRQ

Target ORF information:

RefSeq Version	XM_008261791.2
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus ATP binding cassette subfamily B member 1 (ABCB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008261791.2

ORF Insert Sequence:

ATGGACATCG AAGGGGAACG CAATGGACGG CTCGGGAAGA ACATGTACAA GCTGAACAAG 
AGAAATAAAA AAGAAAAGGA AAAGAGACCA ACTGTCAGCG CATTTGCAAT GTTCCGCTAT 
TCAAATTGGC TTGATAAATT GTACATGGTG GTGGGGACCT TGGCTGCCAT CATCCATGGA 
GCTGCACTGC CCCTCATGAT GCTGGTGTTT GGAGACATGA CGGACAGCTT TTCAAACCCA 
GGAAATATGA TTCCAGCAAA CATCACTAAT CTTAACATGA GTAACATCAG CGCCTCTGAG 
ATCTACAAAC ATCTGGAGGA AGAAATGACC ACGTACGCCT ACTACTACAG TGGAATTGGT 
GCTGGTGTGC TTGTTGCTGC TTACATTCAG GTTTCGTTTT GGTGCTTGGC AGCTGGAAGA 
CAAACATTTA AAATTAGAAA ACAGTTTTTT CATTCCATAA TGCGCCAGGA GATAGGCTGG 
TTTGACGTGC ATGATGTTGG AGAGCTGAAC ACCCGGCTCA CAGATGATGT CTCCAAAATT 
AATGACGGGA TTGGTGACAA AATTGGAATG TTCTTTCAGT CAATGTCAAC ATTTTTCACC 
GGTTTTATAG TAGGATTTAC ACGTGGTTGG AAACTAACCC TGGTGATTTT GGCCATTAGT 
CCTGTTCTTG GACTCTCAGC TGCTCTCTGG GCAAAGATAA TGTCTTCATT TACTGATAAA 
GAACTGTTGG CGTATGCAAA AGCAGGAGCT GTGGCTGAAG AGGTCCTAGC GGCAATTAGA 
ACTGTGATTG CGTTTGGAGG ACAACAGAAG GAACTGGAAA GGTACAATAA AAATTTAGAA 
GAAGCTAAAA GAATTGGGAT AAAGAAAGCT ATTACAGCCA ACATCTCTGT GGGTGTTGCT 
TTCCTGCTGA TGTATGCATC GTATGCGCTG GCCTTCTGGT ATGGAACCAC CTTGGTCATC 
TCAAAAGAAT ATTCTATCGG ACAAGTGCTC ACTGTCTTCT TTTCTGTATT AGTTGGAGCT 
TTCAGTATTG GCCAAGCATC TCCAAATGTT GAAGCATTTG CAAATGCAAG AGGAGCAGCT 
TATGAAATCT TCAGGATCAT CGATAATAAG CCGAGCATTG ACAGCTACTC GGAGGCCGGG 
CACAAACCAG ATAATATTAA AGGAAATTTG GAATTCAGAA ATGTTCATTT CAGCTACCCT 
TCTCGAAAAG AAGTTAAGAT CTTGAAGGGC CTCAACCTGA AGGTGGAGAG CGGGCAGACG 
GTGGCCCTGG TGGGGAACAG TGGCTGTGGG AAGAGCACGA CCGTCCAGCT GATGCAGAGA 
CTCTATGACC CCACGGACGG CGTGGTCAGC ATTGATGGCC AGGACATCAG GACCATGAAC 
GTGAGGTATC TGCGGGAAAT TACCGGCGTG GTGAGTCAGG AACCTGTGTT GTTCGCCACC 
ACAATCGCTG AGAACATCCG CTATGGCCGA GAAGATGTCA CCATGGATGA GATTGAAAAG 
GCTGTCAAGG AAGCCAACGC CTACAACTTT ATCATGAAGC TACCTCATAA ATTCGACACT 
CTGGTTGGAG AGAGAGGGGC CCAGCTGAGC GGTGGGCAGA AACAGAGGAT CGCCATTGCC 
CGTGCCCTGG TTCGCAACCC CAAGATCCTC CTGCTGGACG AGGCCACCTC AGCCTTGGAC 
ACAGAAAGTG AAGCTGTGGT TCAGGTGGCT CTAGATAAGG CTAGAAAAGG CCGCACAACT 
ATTGTGATAG CTCACCGCCT GTCTACAGTT CGCAATGCTG ATGTCATTGC TGGATTTGAT 
AATGGAGTCA TTGTGGAGAG AGGAAATCAT GAGGAACTCA TGAGGCAGAA AGGCGTTTAC 
TTCAGACTTG TCACAATGCA GACAGCAGGA AATGAAATTG ACTTAGAAAA TTCAGCTAGT 
GAATCTAGAG GTGAAAAAAT GGATTTGGTG GAAATGTCTG CTAAAGAGTC AGGATCCAGT 
CTGATAAGAA GGAGATCAAG TCACAAGAGT TTTCATGGAG CTCAAGGCCA AGATGGGAAG 
CTTAGCACTA CAGAGGCCCA GAATGAAAAT GTACCTCCAG TTTCCTTTTG GAGAATTATG 
AAGCTGAATT TAACTGAATG GCCTTATTTT TTGGTGGGTG TAATTTGTGC CATTATAAAT 
GGAGGCCTAC AACCAGCATT TGCAGTAGTA TTTTCAAAGA TTGTGGGAGT TTTCACAAGA 
AATGATGATG ATGAAACAAA ACGGCGGAAT AGTGACCTGT TTTCCTTGTT GTTCCTCATC 
CTTGGAATTA TTTCCTTTAT TACATTTTTC CTTCAGGGCT TCACCTTTGG CAAAGCCGGG 
GAAATCCTCA CCAAGCGCCT GCGCTACATG GTGTTCAAGT CCATGCTGAG ACAGGATGTG 
AGCTGGTTCG ATGACCCTAA AAACACAACT GGAGCGTTGA CCACCAGGCT TGCCAATGAC 
GCTGCTCAGG TCAAAGGGGC GACTGGTTCC AGGCTTGCTG TAATTGCTCA GAACATAGCT 
AATCTTGGGA CAGGAATTAT TATATCCTTA GTCTATGGTT GGCAGTTAAC ACTTCTGCTC 
TTAGCAATTG TACCCATCAT CGCAATAGCT GGAGTTGTTG AAATGAAAAT GTTGTCTGGG 
CAGGCACTAA AAGATAAGAA AGAACTGGAA GGTTCCGGAA AGATTGCCAC AGAAGCAATA 
GAGAACTTCC GAACAGTCGT GTCTCTGACT CGTGAGCAGA AGTTTGAAAA TATGTATGCG 
CAGAGTTTGC AGGTGCCATA CAGAAACTCC TTGAAGAAAG CACACATCTT TGGAATCACA 
TTCTCCTTCA CCCAGGCCAT GATGTATTTT TCCTATGCTG GCTGTTTCCG ATTTGGTGCC 
TTCCTGGTGG CACGGGAACT GATGAGCTTC GAAAATGTTC TGTTGGTCTT TTCAGCAGTC 
GTCTTTGGTG CCATGGCGGT CGGGCAGGTC AGCTCATTTG CCCCTGACTA TGCCAAAGCC 
AAGATCTCGG CTTCCCACAT CATCATGATC CTTGAGAAAC TCCCAAAGAT TGACAGCTAC 
AGCACGGAGG GCCTCAAGCT AGGTACGTTG GAAGGTAATA TGACCTTTAA GGATGTTGTG 
TTCAACTATC CCACCCGACC CGACATCCCA GTGCTGCAGG GGCTGAACCT GCAGGTGAAG 
AAGGGCCAGA CGCTGGCCCT GGTGGGCCCC AGTGGCTGCG GCAAGAGCAC CGTGGTGCAG 
CTCATTGAGC GGTTCTACGA CCCCTTGGCC GGAACAGTGC TATTGGATGG CAAAGAAGTA 
AATCAACTGA ATGTGCAGTG GCTGCGAGCC CACCTGGGAA TTGTGTCCCA GGAGCCCATC 
CTGTTTGACT GCAGCATCGC CGAGAACATC GCCTATGGAG ACAATAGCCG GGTGGTGTCC 
CAGGACGAGA TCATTAAGGC AGCCAAAGAG GCCAACATCC ACGCCTTCAT CGACTCCTTG 
CCTGACAAAT ACAACACCAG GGTGGGAGAC AAGGGAACCC AGCTCTCCGG CGGCCAGAAG 
CAGCGGATTG CCATCGCCCG CGCCCTCGTG CGGCAGCCGC ACATCCTGCT TCTGGACGAA 
GCCACGTCGG CTCTGGATAC AGAAAGTGAG AAGGTGGTCC AAGAAGCCCT GGACAAGGCC 
CGGGAGGGCC GCACCTGCGT CGTGATCGCG CACCGCCTGT CCACCATCCA GAACGCAGAC 
ATGATAGTGG TGTTCCAAAA CGGCAGAGTC AAAGAGTGCG GCACTCACCA CCAGCTGCTG 
GCACAGAAAG GCATCTACTT CTCCATGGTC AGTGTCCAGG CTGGAGGAAA GCGCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The effect of pomelo mix ethyl acetate extract on CYP3A6 and P-glycoprotein gene transcripts in rabbits.
Drug metabolism letters7(2)137-40(2014 Jul)
Irshaid YM,Zihlef MA,Zmeili SM,Al-Antary ET,Zmaily MG,Al-Embideen SN,Amireh AO

Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies.
International journal of pharmaceutics441(1-2)765-75(2013 Jan)
Verstraelen J,Reichl S

Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.
Drug metabolism and disposition: the biological fate of chemicals37(8)1718-25(2009 Aug)
Majumdar S,Hippalgaonkar K,Srirangam R

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ABCB1 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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