PLAU cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLAU
Entrez Gene ID	100008633
Full Name	plasminogen activator, urokinase
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
XM_008269903.2	XP_008268125.1	urokinase-type plasminogen activator isoform X1
NM_001082011.1	NP_001075480.1	urokinase-type plasminogen activator precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Immunohistochemical profile of NF-κB/p50, NF-κB/p65, MMP-9, MMP-2, and u-PA in experimental cervical spondylotic myelopathy.
Karadimas SK, Klironomos G, Papachristou DJ, Papanikolaou S, Papadaki E, Gatzounis G
Spine38(1)4-10(2013 Jan)

Constriction of carotid arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH(2)-terminal domains.
Massey PG, Tanaka S, Buckler JM, Jiang B, McCourtie A, Qian K, Tom C, Stempien-Otero A, Wen S, Luttrell I, Chitaley K, Dichek DA
Thrombosis and haemostasis102(5)983-92(2009 Nov)

Downregulation of urokinase-type and tissue-type plasminogen activators in a rabbit model of renal ischemia/reperfusion.
Sugiki M, Omura S, Yoshida E, Itoh H, Kataoka H, Maruyama M
Journal of biochemistry132(3)501-8(2002 Sep)

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth.
Falkenberg M, Tom C, DeYoung MB, Wen S, Linnemann R, Dichek DA
Proceedings of the National Academy of Sciences of the United States of America99(16)10665-70(2002 Aug)

Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament.
Reno C, Boykiw R, Martinez ML, Hart DA
Biochemical and biophysical research communications252(3)757-63(1998 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PLAU gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLAU cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOb00171	NM_001082011.1 Latest version!	Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OOb00171	XM_008269903.2 Latest version!	Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLAU ( NM_001082011.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001075480.1 Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), mRNA.

Price & Availability↑

CloneID	OOb00171
Clone ID Related Accession (Same CDS sequence)	XM_008269903.2 , NM_001082011.1
Accession Version	NM_001082011.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562256000000
Organism	Oryctolagus cuniculus(rabbit)
Product	urokinase-type plasminogen activator precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB087224.1. ##Evidence-Data-START## Transcript exon combination :: AB087224.1, AY122285.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03328715, SAMN03328716 [ECO:0000348] ##Evidence-Data-END##

ATGAGAGTCC TCCTGGTATG CCTGCTTCTC TGCGCCCTGG TCGTGAGCGA CTCCGAAGGA 
AGCCATGAAC TTCACGGAGT GTCTGATGCT TCAAACTGCG GCTGTCTGAA TGGAGGAACA 
TGTGTGACCT ACAAGTACTT CTCCAACATT TGGCGATGTA ACTGCCCAAA GAAATTCCAA 
GGAGAGCACT GTGAGATAGA TACATTGAAA ACCTGCTATC ATGGGGATGG TCACTCTTAT 
CGTGGAAAGG CCAACACTGA CATCATGGAT CGACCCTGCC TTGCCTGGAA CTCTGCCAAT 
GTTCTTACGA AAACATACCA TGCCCACAGA CCTGATGCCC TTCAGCTGGG CTTGGGGAAA 
CACAATTACT GCAGGAACCC AGACCACCAG AGAAGACCCT GGTGCTATGT GCAGGTTGGC 
CTAAAGCAGC TCATCCAAGA GTGCAAGGTG CATGACTGCT CTTCAGGAAA AAAACCTGCC 
CTTCCTCCAG GAAAATTGGA GTTTCAGTGT GGCCAGAAGG CTCTGAGGCC CCGTTTTAAG 
ATTATTGGGG GAGAATTCAC CATCATTGAG AACCAGCCCT GGTTTGCAGC CATCTACAGG 
AGGCACCGGG GAGGCTCTGT CACTTATGTG TGTGGCGGCA GCCTCATCAG TCCTTGCTGG 
GTGGTCAGCG CCACACATTG CTTCATTAAT CACCAAAAGA AAGAGGACTA CATTGTCTAC 
CTGGGTCGGT CAAGGCTTAA CTCCATGACA CCTGGGGAGA TGAAGTTTGA AGTGGAGCAA 
CTCATCTTGC ATGAGGGCTA TAGAGCTGAC ACACTGGCTC ATCACAACGA TATTGCCTTG 
CTGAAGATAC TTTCCAACAA TGGCCAATGT GCTCAGCCAT CCCGGTCCAT ACAGACTATT 
TGCCTGCCCC CATGGAATGC TGATCCCAAT TTTGGCACAA GCTGTGAGAT CACCGGCTTT 
GGAAAAGAGA ATTCCACCGA CTACTTGTAT CCAGAGCAGC TGAAAATGAC TGTGGTGAAG 
CTGGTTTCCT ACCAGGAGTG TCAGCAACCC CATTACTATG GCTCTGAAGT CACCACCAAA 
ATGCTTTGTG CCGCTGACCC ACAGTGGGAA ACAGATTCCT GCCAGGGAGA CTCAGGAGGG 
CCCCTAGTCT GCTCCGTTCA AGGCCGTATG ACTCTGACTG GGATTGTGAG CTGGGGCCGT 
GGATGTGCCT TGAAGAATAA GCCAGGTGTC TATACAAGAG TCTCACGCTT CCTGCCCTGG 
ATCCGTAGTC ACATTGGGGA AGAGAATGGC CTGGCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001075480.1
CDS	128..1429
Translation	MRVLLVCLLLCALVVSDSEGSHELHGVSDASNCGCLNGGTCVTYKYFSNIWRCNCPKKFQGEHCEIDTLKTCYHGDGHSYRGKANTDIMDRPCLAWNSANVLTKTYHAHRPDALQLGLGKHNYCRNPDHQRRPWCYVQVGLKQLIQECKVHDCSSGKKPALPPGKLEFQCGQKALRPRFKIIGGEFTIIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINHQKKEDYIVYLGRSRLNSMTPGEMKFEVEQLILHEGYRADTLAHHNDIALLKILSNNGQCAQPSRSIQTICLPPWNADPNFGTSCEITGFGKENSTDYLYPEQLKMTVVKLVSYQECQQPHYYGSEVTTKMLCAADPQWETDSCQGDSGGPLVCSVQGRMTLTGIVSWGRGCALKNKPGVYTRVSRFLPWIRSHIGEENGLAL

Target ORF information:

RefSeq Version	NM_001082011.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082011.1

ORF Insert Sequence:

ATGAGAGTCC TCCTGGTATG CCTGCTTCTC TGCGCCCTGG TCGTGAGCGA CTCCGAAGGA 
AGCCATGAAC TTCACGGAGT GTCTGATGCT TCAAACTGCG GCTGTCTGAA TGGAGGAACA 
TGTGTGACCT ACAAGTACTT CTCCAACATT TGGCGATGTA ACTGCCCAAA GAAATTCCAA 
GGAGAGCACT GTGAGATAGA TACATTGAAA ACCTGCTATC ATGGGGATGG TCACTCTTAT 
CGTGGAAAGG CCAACACTGA CATCATGGAT CGACCCTGCC TTGCCTGGAA CTCTGCCAAT 
GTTCTTACGA AAACATACCA TGCCCACAGA CCTGATGCCC TTCAGCTGGG CTTGGGGAAA 
CACAATTACT GCAGGAACCC AGACCACCAG AGAAGACCCT GGTGCTATGT GCAGGTTGGC 
CTAAAGCAGC TCATCCAAGA GTGCAAGGTG CATGACTGCT CTTCAGGAAA AAAACCTGCC 
CTTCCTCCAG GAAAATTGGA GTTTCAGTGT GGCCAGAAGG CTCTGAGGCC CCGTTTTAAG 
ATTATTGGGG GAGAATTCAC CATCATTGAG AACCAGCCCT GGTTTGCAGC CATCTACAGG 
AGGCACCGGG GAGGCTCTGT CACTTATGTG TGTGGCGGCA GCCTCATCAG TCCTTGCTGG 
GTGGTCAGCG CCACACATTG CTTCATTAAT CACCAAAAGA AAGAGGACTA CATTGTCTAC 
CTGGGTCGGT CAAGGCTTAA CTCCATGACA CCTGGGGAGA TGAAGTTTGA AGTGGAGCAA 
CTCATCTTGC ATGAGGGCTA TAGAGCTGAC ACACTGGCTC ATCACAACGA TATTGCCTTG 
CTGAAGATAC TTTCCAACAA TGGCCAATGT GCTCAGCCAT CCCGGTCCAT ACAGACTATT 
TGCCTGCCCC CATGGAATGC TGATCCCAAT TTTGGCACAA GCTGTGAGAT CACCGGCTTT 
GGAAAAGAGA ATTCCACCGA CTACTTGTAT CCAGAGCAGC TGAAAATGAC TGTGGTGAAG 
CTGGTTTCCT ACCAGGAGTG TCAGCAACCC CATTACTATG GCTCTGAAGT CACCACCAAA 
ATGCTTTGTG CCGCTGACCC ACAGTGGGAA ACAGATTCCT GCCAGGGAGA CTCAGGAGGG 
CCCCTAGTCT GCTCCGTTCA AGGCCGTATG ACTCTGACTG GGATTGTGAG CTGGGGCCGT 
GGATGTGCCT TGAAGAATAA GCCAGGTGTC TATACAAGAG TCTCACGCTT CCTGCCCTGG 
ATCCGTAGTC ACATTGGGGA AGAGAATGGC CTGGCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLAU ( XM_008269903.2 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> XP_008268125.1 Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OOb00171
Clone ID Related Accession (Same CDS sequence)	XM_008269903.2 , NM_001082011.1
Accession Version	XM_008269903.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466524800000
Organism	Oryctolagus cuniculus(rabbit)
Product	urokinase-type plasminogen activator isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013686.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008269903.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGTCC TCCTGGTATG CCTGCTTCTC TGCGCCCTGG TCGTGAGCGA CTCCGAAGGA 
AGCCATGAAC TTCACGGAGT GTCTGATGCT TCAAACTGCG GCTGTCTGAA TGGAGGAACA 
TGTGTGACCT ACAAGTACTT CTCCAACATT TGGCGATGTA ACTGCCCAAA GAAATTCCAA 
GGAGAGCACT GTGAGATAGA TACATTGAAA ACCTGCTATC ATGGGGATGG TCACTCTTAT 
CGTGGAAAGG CCAACACTGA CATCATGGAT CGACCCTGCC TTGCCTGGAA CTCTGCCAAT 
GTTCTTACGA AAACATACCA TGCCCACAGA CCTGATGCCC TTCAGCTGGG CTTGGGGAAA 
CACAATTACT GCAGGAACCC AGACCACCAG AGAAGACCCT GGTGCTATGT GCAGGTTGGC 
CTAAAGCAGC TCATCCAAGA GTGCAAGGTG CATGACTGCT CTTCAGGAAA AAAACCTGCC 
CTTCCTCCAG GAAAATTGGA GTTTCAGTGT GGCCAGAAGG CTCTGAGGCC CCGTTTTAAG 
ATTATTGGGG GAGAATTCAC CATCATTGAG AACCAGCCCT GGTTTGCAGC CATCTACAGG 
AGGCACCGGG GAGGCTCTGT CACTTATGTG TGTGGCGGCA GCCTCATCAG TCCTTGCTGG 
GTGGTCAGCG CCACACATTG CTTCATTAAT CACCAAAAGA AAGAGGACTA CATTGTCTAC 
CTGGGTCGGT CAAGGCTTAA CTCCATGACA CCTGGGGAGA TGAAGTTTGA AGTGGAGCAA 
CTCATCTTGC ATGAGGGCTA TAGAGCTGAC ACACTGGCTC ATCACAACGA TATTGCCTTG 
CTGAAGATAC TTTCCAACAA TGGCCAATGT GCTCAGCCAT CCCGGTCCAT ACAGACTATT 
TGCCTGCCCC CATGGAATGC TGATCCCAAT TTTGGCACAA GCTGTGAGAT CACCGGCTTT 
GGAAAAGAGA ATTCCACCGA CTACTTGTAT CCAGAGCAGC TGAAAATGAC TGTGGTGAAG 
CTGGTTTCCT ACCAGGAGTG TCAGCAACCC CATTACTATG GCTCTGAAGT CACCACCAAA 
ATGCTTTGTG CCGCTGACCC ACAGTGGGAA ACAGATTCCT GCCAGGGAGA CTCAGGAGGG 
CCCCTAGTCT GCTCCGTTCA AGGCCGTATG ACTCTGACTG GGATTGTGAG CTGGGGCCGT 
GGATGTGCCT TGAAGAATAA GCCAGGTGTC TATACAAGAG TCTCACGCTT CCTGCCCTGG 
ATCCGTAGTC ACATTGGGGA AGAGAATGGC CTGGCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008268125.1
CDS	51..1352
Translation	MRVLLVCLLLCALVVSDSEGSHELHGVSDASNCGCLNGGTCVTYKYFSNIWRCNCPKKFQGEHCEIDTLKTCYHGDGHSYRGKANTDIMDRPCLAWNSANVLTKTYHAHRPDALQLGLGKHNYCRNPDHQRRPWCYVQVGLKQLIQECKVHDCSSGKKPALPPGKLEFQCGQKALRPRFKIIGGEFTIIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINHQKKEDYIVYLGRSRLNSMTPGEMKFEVEQLILHEGYRADTLAHHNDIALLKILSNNGQCAQPSRSIQTICLPPWNADPNFGTSCEITGFGKENSTDYLYPEQLKMTVVKLVSYQECQQPHYYGSEVTTKMLCAADPQWETDSCQGDSGGPLVCSVQGRMTLTGIVSWGRGCALKNKPGVYTRVSRFLPWIRSHIGEENGLAL

Target ORF information:

RefSeq Version	XM_008269903.2
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus plasminogen activator, urokinase (PLAU), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008269903.2

ORF Insert Sequence:

ATGAGAGTCC TCCTGGTATG CCTGCTTCTC TGCGCCCTGG TCGTGAGCGA CTCCGAAGGA 
AGCCATGAAC TTCACGGAGT GTCTGATGCT TCAAACTGCG GCTGTCTGAA TGGAGGAACA 
TGTGTGACCT ACAAGTACTT CTCCAACATT TGGCGATGTA ACTGCCCAAA GAAATTCCAA 
GGAGAGCACT GTGAGATAGA TACATTGAAA ACCTGCTATC ATGGGGATGG TCACTCTTAT 
CGTGGAAAGG CCAACACTGA CATCATGGAT CGACCCTGCC TTGCCTGGAA CTCTGCCAAT 
GTTCTTACGA AAACATACCA TGCCCACAGA CCTGATGCCC TTCAGCTGGG CTTGGGGAAA 
CACAATTACT GCAGGAACCC AGACCACCAG AGAAGACCCT GGTGCTATGT GCAGGTTGGC 
CTAAAGCAGC TCATCCAAGA GTGCAAGGTG CATGACTGCT CTTCAGGAAA AAAACCTGCC 
CTTCCTCCAG GAAAATTGGA GTTTCAGTGT GGCCAGAAGG CTCTGAGGCC CCGTTTTAAG 
ATTATTGGGG GAGAATTCAC CATCATTGAG AACCAGCCCT GGTTTGCAGC CATCTACAGG 
AGGCACCGGG GAGGCTCTGT CACTTATGTG TGTGGCGGCA GCCTCATCAG TCCTTGCTGG 
GTGGTCAGCG CCACACATTG CTTCATTAAT CACCAAAAGA AAGAGGACTA CATTGTCTAC 
CTGGGTCGGT CAAGGCTTAA CTCCATGACA CCTGGGGAGA TGAAGTTTGA AGTGGAGCAA 
CTCATCTTGC ATGAGGGCTA TAGAGCTGAC ACACTGGCTC ATCACAACGA TATTGCCTTG 
CTGAAGATAC TTTCCAACAA TGGCCAATGT GCTCAGCCAT CCCGGTCCAT ACAGACTATT 
TGCCTGCCCC CATGGAATGC TGATCCCAAT TTTGGCACAA GCTGTGAGAT CACCGGCTTT 
GGAAAAGAGA ATTCCACCGA CTACTTGTAT CCAGAGCAGC TGAAAATGAC TGTGGTGAAG 
CTGGTTTCCT ACCAGGAGTG TCAGCAACCC CATTACTATG GCTCTGAAGT CACCACCAAA 
ATGCTTTGTG CCGCTGACCC ACAGTGGGAA ACAGATTCCT GCCAGGGAGA CTCAGGAGGG 
CCCCTAGTCT GCTCCGTTCA AGGCCGTATG ACTCTGACTG GGATTGTGAG CTGGGGCCGT 
GGATGTGCCT TGAAGAATAA GCCAGGTGTC TATACAAGAG TCTCACGCTT CCTGCCCTGG 
ATCCGTAGTC ACATTGGGGA AGAGAATGGC CTGGCCCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Immunohistochemical profile of NF-κB/p50, NF-κB/p65, MMP-9, MMP-2, and u-PA in experimental cervical spondylotic myelopathy.
Spine38(1)4-10(2013 Jan)
Karadimas SK,Klironomos G,Papachristou DJ,Papanikolaou S,Papadaki E,Gatzounis G

Constriction of carotid arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH(2)-terminal domains.
Thrombosis and haemostasis102(5)983-92(2009 Nov)
Massey PG,Tanaka S,Buckler JM,Jiang B,McCourtie A,Qian K,Tom C,Stempien-Otero A,Wen S,Luttrell I,Chitaley K,Dichek DA

Downregulation of urokinase-type and tissue-type plasminogen activators in a rabbit model of renal ischemia/reperfusion.
Journal of biochemistry132(3)501-8(2002 Sep)
Sugiki M,Omura S,Yoshida E,Itoh H,Kataoka H,Maruyama M

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth.
Proceedings of the National Academy of Sciences of the United States of America99(16)10665-70(2002 Aug)
Falkenberg M,Tom C,DeYoung MB,Wen S,Linnemann R,Dichek DA

Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament.
Biochemical and biophysical research communications252(3)757-63(1998 Nov)
Reno C,Boykiw R,Martinez ML,Hart DA

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PLAU cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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