Tmem97 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem97
Entrez Gene ID	69071
Full Name	transmembrane protein 97
Synonyms	1810014L12Rik,AI115531,AL022956,D11Bhm182e
General protein information	Preferred Names transmembrane protein 97 Names sigma intracellular receptor 2 sigma-2 receptor sigma2 receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 B5\|11 46.74 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_133706.2	NP_598467.1	sigma intracellular receptor 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMEM97	NP_055388.2
Macaca mulatta (Rhesus monkey)	TMEM97	XP_001106505.1
Bos taurus (cattle)	TMEM97	NP_001029575.1
Danio rerio (zebrafish)	LOC569147	XP_697605.1
Pan troglodytes (chimpanzee)	TMEM97	NP_001238843.1
Mus musculus (house mouse)	Tmem97	NP_598467.1
Rattus norvegicus (Norway rat)	Tmem97	NP_001008335.1
Gallus gallus (chicken)	TMEM97	XP_415916.1
Xenopus tropicalis (tropical clawed frog)	tmem97	NP_001005014.1
Canis lupus familiaris (dog)	TMEM97	XP_853562.2

Gene Ontology
Bibliography

Related articles in PubMed

Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice.
Sahn JJ, Mejia GL, Ray PR, Martin SF, Price TJ
ACS chemical neuroscience8(8)1801-1811(2017 08)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.
Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K
Genomics74(2)234-44(2001 Jun)

YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.
Nehls M, Lüno K, Schorpp M, Pfeifer D, Krause S, Matysiak-Scholze U, Dierbach H, Boehm T
Mammalian genome : official journal of the International Mammalian Genome Society6(5)321-31(1995 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tmem97 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem97 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19441	NM_133706.2 Latest version!	Mus musculus transmembrane protein 97 (Tmem97), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem97 ( NM_133706.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598467.1 Mus musculus transmembrane protein 97 (Tmem97), mRNA.

Price & Availability↑

CloneID	OMu19441
Clone ID Related Accession (Same CDS sequence)	NM_133706.2
Accession Version	NM_133706.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Mus musculus(house mouse)
Product	sigma intracellular receptor 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591177.14. On Nov 17, 2006 this sequence version replaced NM_133706.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC018156.1, AK155107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCCC TGGCAGCTAG GCGCTGTGTC GAGTGGCTCT TGGGCCTCTA CTTCGTCTCG 
CACATCCCCA TCACGCTGTT CATCGACCTG CAGGCGGTGC TGCCGCCCGA ACTATACCCG 
CAGGAGTTCA GCAACCTGTT GCGGTGGTAC TCAAAGGAGT TCAAAGACCC TCTGATGCAG 
GAGCCCCCAG TGTGGTTCAA GTCCTTCCTG CTCTGTGAGC TTGTGTTCCA GCTGCCTTTC 
TTTCCCATTG CGGCATATGC CTTCTTCAAA GGAAGCTGCC GGTGGATCCG AATCCCTGCA 
ATCATCTATG CAGCTCACAC CATAACGACT TTAATTCCAA TCCTCTACAC ACTCCTGTTT 
GAGGATTTCT CTAAAGCCGT TGCTTTCAAG GGACAAAGAC CCGAGAGTTT CCGTGAACGA 
CTGACCCTCG TAGGTGTCTA CGCCCCCTAT TTAATAATCC CCCTCATACT CCTCCTGTTC 
ATGCTTCGGA ACCCGTACTA CAAGTATGAG GAGAAAAGAA AGAAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598467.1
CDS	83..613
Translation	MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLFEDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK

Target ORF information:

RefSeq Version	NM_133706.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 97 (Tmem97), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133706.2

ORF Insert Sequence:

ATGGGGGCCC TGGCAGCTAG GCGCTGTGTC GAGTGGCTCT TGGGCCTCTA CTTCGTCTCG 
CACATCCCCA TCACGCTGTT CATCGACCTG CAGGCGGTGC TGCCGCCCGA ACTATACCCG 
CAGGAGTTCA GCAACCTGTT GCGGTGGTAC TCAAAGGAGT TCAAAGACCC TCTGATGCAG 
GAGCCCCCAG TGTGGTTCAA GTCCTTCCTG CTCTGTGAGC TTGTGTTCCA GCTGCCTTTC 
TTTCCCATTG CGGCATATGC CTTCTTCAAA GGAAGCTGCC GGTGGATCCG AATCCCTGCA 
ATCATCTATG CAGCTCACAC CATAACGACT TTAATTCCAA TCCTCTACAC ACTCCTGTTT 
GAGGATTTCT CTAAAGCCGT TGCTTTCAAG GGACAAAGAC CCGAGAGTTT CCGTGAACGA 
CTGACCCTCG TAGGTGTCTA CGCCCCCTAT TTAATAATCC CCCTCATACT CCTCCTGTTC 
ATGCTTCGGA ACCCGTACTA CAAGTATGAG GAGAAAAGAA AGAAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice.
ACS chemical neuroscience8(8)1801-1811(2017 08)
Sahn JJ,Mejia GL,Ray PR,Martin SF,Price TJ

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.
Genomics74(2)234-44(2001 Jun)
Mink M,Fogelgren B,Olszewski K,Maroy P,Csiszar K

YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.
Mammalian genome : official journal of the International Mammalian Genome Society6(5)321-31(1995 May)
Nehls M,Lüno K,Schorpp M,Pfeifer D,Krause S,Matysiak-Scholze U,Dierbach H,Boehm T

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Tmem97 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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