Kdm7a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm7a
Entrez Gene ID	338523
Full Name	lysine (K)-specific demethylase 7A
Synonyms	A630082K20Rik,BB041802,Jhdm1d,mKIAA1718
General protein information	Preferred Names lysine (K)-specific demethylase 7A Names lysine-specific demethylase 7A jmjC domain-containing histone demethylation protein 1D jumonji C domain-containing histone demethylase 1 homolog D lysine-specific demethylase 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033430.4	NP_001028602.2	lysine-specific demethylase 7A

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	JHDM1D	XP_001109325.1
Canis lupus familiaris (dog)	JHDM1D	XP_005629614.1
Homo sapiens (human)	KDM7A	NP_085150.1
Bos taurus (cattle)	JHDM1D	XP_002687114.2
Pan troglodytes (chimpanzee)	JHDM1D	XP_527907.3
Mus musculus (house mouse)	Kdm7a	NP_001028602.2
Gallus gallus (chicken)	JHDM1D	XP_416344.4
Danio rerio (zebrafish)	kdm7ab	NP_001189348.1
Xenopus tropicalis (tropical clawed frog)	kdm7a	NP_001072664.1
Rattus norvegicus (Norway rat)	Jhdm1d	XP_006236422.1

Gene Ontology
Bibliography

Related articles in PubMed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A
Nature537(7621)548-552(2016 09)

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Liakath-Ali K, Vancollie VE, Heath E, Smedley DP, Estabel J, Sunter D, Ditommaso T, White JK, Ramirez-Solis R, Smyth I, Steel KP, Watt FM
Nature communications53540(2014 Apr)

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.
Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M
Proceedings of the National Academy of Sciences of the United States of America108(51)20725-9(2011 Dec)

The dual histone demethylase KDM7A promotes neural induction in early chick embryos.
Huang C, Chen J, Zhang T, Zhu Q, Xiang Y, Chen CD, Jing N
Developmental dynamics : an official publication of the American Association of Anatomists239(12)3350-7(2010 Dec)

KIAA1718 is a histone demethylase that erases repressive histone methyl marks.
Yokoyama A, Okuno Y, Chikanishi T, Hashiba W, Sekine H, Fujiki R, Kato S
Genes to cells : devoted to molecular & cellular mechanisms15(8)867-73(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kdm7a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm7a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21115	NM_001033430.4 Latest version!	Mus musculus lysine (K)-specific demethylase 7A (Kdm7a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm7a ( NM_001033430.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028602.2 Mus musculus lysine (K)-specific demethylase 7A (Kdm7a), mRNA.

Price & Availability↑

CloneID	OMu21115
Clone ID Related Accession (Same CDS sequence)	NM_001033430.4
Accession Version	NM_001033430.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2823bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 7A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK042834.1, BC145848.1, AK129429.1, AC153818.5 and AW549902.2. On Nov 15, 2007 this sequence version replaced NM_001033430.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.134946.1, BC145848.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGGAG CGGCGGCGGC GGTGGCCGCG GGAGCAGCAG CTGGAGCCGC CGCGGCAGCG 
GGGTCGGTGT CCGCTCCGGG TCGGGCCTCG GCGCCCCCTC CGCCTCCGCC CGTGTACTGT 
GTATGCCGGC AGCCGTACGA CGTGAACCGC TTCATGATCG AGTGCGATGT CTGCAAGGAC 
TGGTTCCACG GCAGCTGTGT TGGCGTGGAA GAGCATCATG CTGTGGACAT TGACCTGTAC 
CACTGCCCGG ACTGTGCAGC TCTACACGGC TCTTCCTTAA TGAAGAAGAG GAGGAACTGG 
CACAGGCATG ACTACACAGA AGTGGATGAT GGCTCCAAAC CTGTTCAAGC TGGAACTAGG 
GCCTTTGTTA AAGAACTACG TTCTCGAGTC TTCCCAAGTG CCGATGAAAT CATTGTAAAG 
ATGCATGGCA GTCAGCTGAC ACAAAGATAT CTGGAGAAAC ATGGATTTGA TGTCCCTATT 
ATGGTCCCTA AATTAGATGA CCTTGGACTC AGGCTCCCTT CACCTGCTTT TTCAGTGATG 
GATGTGGAAC GTTATGTAGG TGGTGACAAA GTGATAGATG TTATTGATGT GGCAAGGCAG 
GCGGACAGCA AAATGACACT TCACAATTAT GTTAAATACT TCATGAATCC TGACAGACCA 
AAAGTGCTAA ATGTGATCAG CCTTGAATTT TCGGATACAA AAATGTCTGA ATTGGTGGAG 
GTTCCTGATA TAGCCAGAAA ACTTTCATGG GTGGAAAATT ACTGGCCAGA TGATTCAGTC 
TTCCCCAAGC CCTTTGTCCA GAAATACTGC TTAATGGGAG TTCAAGATAG CTATACAGAT 
TTCCACATTG ACTTTGGTGG GACTTCAGTC TGGTACCATG TCCTTTGGGG TGAGAAGATT 
TTTTATTTGA TAAAGCCAAC AAATGAAAAT TTGGCACTCT ATGAATCTTG GAGTTCATCT 
GTGACCCAGA GTGAGGTGTT CTTTGGAGAT AAAGTAGATA AATGCTACAA ATGTGTGGTA 
AAGCAGGGAC ATACTTTGTT TGTTCCTACA GGGTGGATCC ATGCTGTGCT CACTTCTCAG 
GACTGTATGG CTTTTGGAGG GAACTTTCTG CACAACCTCA ACATTGGCAT GCAGCTCAGG 
TGTTATGAGA TGGAAAAAAG ACTAAAAACA CCAGATCTTT TCAAATTTCC TTTCTTTGAA 
GCCATATGCT GGTTTGTAGC CAAAAGTTTG CTGGAAACCT TGAAAGAACT GAAAGAAGAT 
GGTTTCCAGC CTCAAAGTTA CTTAGTACAG GGAGTAAAAG CACTGCATAC TGCTTTAAAA 
TTATGGATGA AAAAAGAACT TGTATCTGAA CATGCCTTTG AGATTCCAGA CAATGTTAGA 
CCTGGGCATC TTATTAAGGA ACTTTCTAAA GTAATTCGAG CAATAGAGGA GGAAAATGGC 
AAACCAGTTA AATCTCAGGG AATTCCTTCT GTGTGTCCAG TTTCACGGCC TTCAAATGAG 
GCATCTCCAC CATATCATTC CCGGAGAAAG ATGAGGAAAC TTCGAGATCA TAATGTCCGA 
ACTCCTTCTA ACCTTGACAT TCTTGAGCTC CATACAAGGG AAGTCCTCAA AAGATTAGAG 
ATGTGTCCAT GGGAGGAGGA CCTACTGAGC TCTAAACTGA ATGGAAAATT CAACAAACAT 
CTCCAGCCAT CTTCCACAGT ACCTGAGTGG AGAGCGAAAG ATAATGATCT ACGATTACTG 
CTGACAAATG GAAGAATAAT TAAAGATGAG AGACAGCTGT TTGCAGATCG AAGTCTTTAT 
ACAGCAGATA GTGAAAATGA AGAGGACAAG AAGCCAACAC AGAATGCAAA CATGAAGACA 
GAACAGAGCT CAGGAAGAGA GGAGGCCGAA AGTCAAGGCT CTCCCAAACC ACTCAACAGA 
ATCTTTACAA GTGTGAGATC GGAACTCAGG AGTAGACCGT CAGAATATTC TGATGGTTCT 
GATTCAGAAG ACTCTGGACC CGACTGCACT GCACTGAAAA TTAACTTTGC CACTGAAGAT 
TCTGAAAGTT CAGGTGATGA AAAGAAACAT GAAATAACAT CACACTTTAA AGAAGAGTCT 
GATATAGTGA GGAACCTCCT TCAGAAGAGC CAGAAGCCAT CTAGACAGGA AATCCCAGTT 
AAAAGGGAAT GTCCTACCTC GACGAGCACA GAGGAAGAAG CTATTCAGGG CATGCTGTCC 
ATGGCAGGGT TGCACTATTC CTCGTGTTTA CAAAGGCAGA TACAAAGCAC AGATTGCAGT 
GGTGAGAAGA ACTCTCTCCA GGATCCCAGC AGCTGCCACG GCAGTAACCC TGAGTTTAGG 
CAGTTGTATC GCTGCAATAA ACCAGTGGAA TTTGGATACC ATGCCAAGAC TGAAGATCAG 
GATTTGATGA CTTCTTCCTG GAATAAACAG TTTGATCGAA CTTCCAGATT TAATGCTCAG 
GACTTAAGTA GAAGCCAGAA ACACATCAAA AAGGAAAGCT CTTCAGAAAT CAATCAGAAG 
GCACAAAGCA GGCATTGTGT GGACAGCAAT AGCTCAAGCA TTCAGAATGG AAAGTACACG 
CTGAATCCCA GCTTGGTTTC ATGCCAGATA AGTAATGGCA GCCTGAGCCC AGAAAGGCCT 
ATTGGTGAAA CTTCTTTTTC AATGCCCCTT CACCCCACCA AGAGACCTGC ATCAAACCCA 
CCACCTATCA GCAACCAGGC AACAAAAGGT AAACGTCCAA AAAAAGGAAT GGCAACAGCC 
AAACAACGTC TTGGGAAGAT TCTGAAATTG AACAGAAATG GCCATGCTCG CTTCTTCGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028602.2
CDS	140..2962
Translation	MAGAAAAVAAGAAAGAAAAAGSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDCAALHGSSLMKKRRNWHRHDYTEVDDGSKPVQAGTRAFVKELRSRVFPSADEIIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPDRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKELKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPSVCPVSRPSNEASPPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDLLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFADRSLYTADSENEEDKKPTQNANMKTEQSSGREEAESQGSPKPLNRIFTSVRSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRNLLQKSQKPSRQEIPVKRECPTSTSTEEEAIQGMLSMAGLHYSSCLQRQIQSTDCSGEKNSLQDPSSCHGSNPEFRQLYRCNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKHIKKESSSEINQKAQSRHCVDSNSSSIQNGKYTLNPSLVSCQISNGSLSPERPIGETSFSMPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV

Target ORF information:

RefSeq Version	NM_001033430.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 7A (Kdm7a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033430.4

ORF Insert Sequence:

ATGGCCGGAG CGGCGGCGGC GGTGGCCGCG GGAGCAGCAG CTGGAGCCGC CGCGGCAGCG 
GGGTCGGTGT CCGCTCCGGG TCGGGCCTCG GCGCCCCCTC CGCCTCCGCC CGTGTACTGT 
GTATGCCGGC AGCCGTACGA CGTGAACCGC TTCATGATCG AGTGCGATGT CTGCAAGGAC 
TGGTTCCACG GCAGCTGTGT TGGCGTGGAA GAGCATCATG CTGTGGACAT TGACCTGTAC 
CACTGCCCGG ACTGTGCAGC TCTACACGGC TCTTCCTTAA TGAAGAAGAG GAGGAACTGG 
CACAGGCATG ACTACACAGA AGTGGATGAT GGCTCCAAAC CTGTTCAAGC TGGAACTAGG 
GCCTTTGTTA AAGAACTACG TTCTCGAGTC TTCCCAAGTG CCGATGAAAT CATTGTAAAG 
ATGCATGGCA GTCAGCTGAC ACAAAGATAT CTGGAGAAAC ATGGATTTGA TGTCCCTATT 
ATGGTCCCTA AATTAGATGA CCTTGGACTC AGGCTCCCTT CACCTGCTTT TTCAGTGATG 
GATGTGGAAC GTTATGTAGG TGGTGACAAA GTGATAGATG TTATTGATGT GGCAAGGCAG 
GCGGACAGCA AAATGACACT TCACAATTAT GTTAAATACT TCATGAATCC TGACAGACCA 
AAAGTGCTAA ATGTGATCAG CCTTGAATTT TCGGATACAA AAATGTCTGA ATTGGTGGAG 
GTTCCTGATA TAGCCAGAAA ACTTTCATGG GTGGAAAATT ACTGGCCAGA TGATTCAGTC 
TTCCCCAAGC CCTTTGTCCA GAAATACTGC TTAATGGGAG TTCAAGATAG CTATACAGAT 
TTCCACATTG ACTTTGGTGG GACTTCAGTC TGGTACCATG TCCTTTGGGG TGAGAAGATT 
TTTTATTTGA TAAAGCCAAC AAATGAAAAT TTGGCACTCT ATGAATCTTG GAGTTCATCT 
GTGACCCAGA GTGAGGTGTT CTTTGGAGAT AAAGTAGATA AATGCTACAA ATGTGTGGTA 
AAGCAGGGAC ATACTTTGTT TGTTCCTACA GGGTGGATCC ATGCTGTGCT CACTTCTCAG 
GACTGTATGG CTTTTGGAGG GAACTTTCTG CACAACCTCA ACATTGGCAT GCAGCTCAGG 
TGTTATGAGA TGGAAAAAAG ACTAAAAACA CCAGATCTTT TCAAATTTCC TTTCTTTGAA 
GCCATATGCT GGTTTGTAGC CAAAAGTTTG CTGGAAACCT TGAAAGAACT GAAAGAAGAT 
GGTTTCCAGC CTCAAAGTTA CTTAGTACAG GGAGTAAAAG CACTGCATAC TGCTTTAAAA 
TTATGGATGA AAAAAGAACT TGTATCTGAA CATGCCTTTG AGATTCCAGA CAATGTTAGA 
CCTGGGCATC TTATTAAGGA ACTTTCTAAA GTAATTCGAG CAATAGAGGA GGAAAATGGC 
AAACCAGTTA AATCTCAGGG AATTCCTTCT GTGTGTCCAG TTTCACGGCC TTCAAATGAG 
GCATCTCCAC CATATCATTC CCGGAGAAAG ATGAGGAAAC TTCGAGATCA TAATGTCCGA 
ACTCCTTCTA ACCTTGACAT TCTTGAGCTC CATACAAGGG AAGTCCTCAA AAGATTAGAG 
ATGTGTCCAT GGGAGGAGGA CCTACTGAGC TCTAAACTGA ATGGAAAATT CAACAAACAT 
CTCCAGCCAT CTTCCACAGT ACCTGAGTGG AGAGCGAAAG ATAATGATCT ACGATTACTG 
CTGACAAATG GAAGAATAAT TAAAGATGAG AGACAGCTGT TTGCAGATCG AAGTCTTTAT 
ACAGCAGATA GTGAAAATGA AGAGGACAAG AAGCCAACAC AGAATGCAAA CATGAAGACA 
GAACAGAGCT CAGGAAGAGA GGAGGCCGAA AGTCAAGGCT CTCCCAAACC ACTCAACAGA 
ATCTTTACAA GTGTGAGATC GGAACTCAGG AGTAGACCGT CAGAATATTC TGATGGTTCT 
GATTCAGAAG ACTCTGGACC CGACTGCACT GCACTGAAAA TTAACTTTGC CACTGAAGAT 
TCTGAAAGTT CAGGTGATGA AAAGAAACAT GAAATAACAT CACACTTTAA AGAAGAGTCT 
GATATAGTGA GGAACCTCCT TCAGAAGAGC CAGAAGCCAT CTAGACAGGA AATCCCAGTT 
AAAAGGGAAT GTCCTACCTC GACGAGCACA GAGGAAGAAG CTATTCAGGG CATGCTGTCC 
ATGGCAGGGT TGCACTATTC CTCGTGTTTA CAAAGGCAGA TACAAAGCAC AGATTGCAGT 
GGTGAGAAGA ACTCTCTCCA GGATCCCAGC AGCTGCCACG GCAGTAACCC TGAGTTTAGG 
CAGTTGTATC GCTGCAATAA ACCAGTGGAA TTTGGATACC ATGCCAAGAC TGAAGATCAG 
GATTTGATGA CTTCTTCCTG GAATAAACAG TTTGATCGAA CTTCCAGATT TAATGCTCAG 
GACTTAAGTA GAAGCCAGAA ACACATCAAA AAGGAAAGCT CTTCAGAAAT CAATCAGAAG 
GCACAAAGCA GGCATTGTGT GGACAGCAAT AGCTCAAGCA TTCAGAATGG AAAGTACACG 
CTGAATCCCA GCTTGGTTTC ATGCCAGATA AGTAATGGCA GCCTGAGCCC AGAAAGGCCT 
ATTGGTGAAA CTTCTTTTTC AATGCCCCTT CACCCCACCA AGAGACCTGC ATCAAACCCA 
CCACCTATCA GCAACCAGGC AACAAAAGGT AAACGTCCAA AAAAAGGAAT GGCAACAGCC 
AAACAACGTC TTGGGAAGAT TCTGAAATTG AACAGAAATG GCCATGCTCG CTTCTTCGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Nature537(7621)548-552(2016 09)
Dahl JA,Jung I,Aanes H,Greggains GD,Manaf A,Lerdrup M,Li G,Kuan S,Li B,Lee AY,Preissl S,Jermstad I,Haugen MH,Suganthan R,Bjørås M,Hansen K,Dalen KT,Fedorcsak P,Ren B,Klungland A

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Nature communications53540(2014 Apr)
Liakath-Ali K,Vancollie VE,Heath E,Smedley DP,Estabel J,Sunter D,Ditommaso T,White JK,Ramirez-Solis R,Smyth I,Steel KP,Watt FM

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America108(51)20725-9(2011 Dec)
Osawa T,Muramatsu M,Wang F,Tsuchida R,Kodama T,Minami T,Shibuya M

The dual histone demethylase KDM7A promotes neural induction in early chick embryos.
Developmental dynamics : an official publication of the American Association of Anatomists239(12)3350-7(2010 Dec)
Huang C,Chen J,Zhang T,Zhu Q,Xiang Y,Chen CD,Jing N

KIAA1718 is a histone demethylase that erases repressive histone methyl marks.
Genes to cells : devoted to molecular & cellular mechanisms15(8)867-73(2010 Aug)
Yokoyama A,Okuno Y,Chikanishi T,Hashiba W,Sekine H,Fujiki R,Kato S

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Kdm7a cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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