Eif3b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif3b
Entrez Gene ID	27979
Full Name	eukaryotic translation initiation factor 3, subunit B
Synonyms	AL033316,AL033334,AL033369,AW208965,D5Wsu45e,EIF3-ETA,EIF3-P110,EIF3-P116,Eif3s9,PRT1
General protein information	Preferred Names eukaryotic translation initiation factor 3, subunit B Names eukaryotic translation initiation factor 3 subunit B eIF-3-eta eIF3 p116 eIF3b eukaryotic translation initiation factor 3 subunit 9 eukaryotic translation initiation factor 3, subunit 9 (eta)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 G2\|5 78.97 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_133916.2	NP_598677.1	eukaryotic translation initiation factor 3 subunit B

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os10g0569200	NP_001065446.1
Bos taurus (cattle)	EIF3B	NP_001095826.1
Mus musculus (house mouse)	Eif3b	NP_598677.1
Rattus norvegicus (Norway rat)	Eif3b	NP_001026810.1
Magnaporthe oryzae (rice blast fungus)	MGG_01978	XP_003708716.1
Gallus gallus (chicken)	EIF3B	XP_003642190.2
Arabidopsis thaliana (thale cress)	EIF3B-2	NP_568477.1
Anopheles gambiae (African malaria mosquito)	EIF3B_ANOGA	XP_320387.3
Eremothecium gossypii	AGOS_ADR399C	NP_984494.1
Arabidopsis thaliana (thale cress)	TIF3B1	NP_568498.1
Kluyveromyces lactis	KLLA0A03531g	XP_451155.1
Pan troglodytes (chimpanzee)	EIF3B	XP_003318263.1
Neurospora crassa	NCU02208	XP_959527.1
Homo sapiens (human)	EIF3B	NP_001032360.1
Macaca mulatta (Rhesus monkey)	EIF3B	XP_001086876.1
Canis lupus familiaris (dog)	EIF3B	XP_536894.3
Danio rerio (zebrafish)	eif3ba	XP_001335480.2
Drosophila melanogaster (fruit fly)	eIF3-S9	NP_725691.1
Saccharomyces cerevisiae (baker's yeast)	PRT1	NP_015006.3
Xenopus tropicalis (tropical clawed frog)	eif3b	NP_001016724.1
Schizosaccharomyces pombe (fission yeast)	SPAC25G10.08	NP_594528.1

Gene Ontology
Bibliography

Related articles in PubMed

The Combination of piR-823 and Eukaryotic Initiation Factor 3 B (EIF3B) Activates Hepatic Stellate Cells via Upregulating TGF-β1 in Liver Fibrogenesis.
Tang X, Xie X, Wang X, Wang Y, Jiang X, Jiang H
Medical science monitor : international medical journal of experimental and clinical research249151-9165(2018 Dec)

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, Hui L, Ji H, Zhu X
The Journal of biological chemistry288(42)30087-93(2013 Oct)

Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.
Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K
BMC genomics13411(2012 Aug)

Reconstitution reveals the functional core of mammalian eIF3.
Masutani M, Sonenberg N, Yokoyama S, Imataka H
The EMBO journal26(14)3373-83(2007 Jul)

A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system.
Neidhardt LM, Kispert A, Herrmann BG
Development genes and evolution207(5)330-339(1997 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18455	NM_133916.2 Latest version!	Mus musculus eukaryotic translation initiation factor 3, subunit B (Eif3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$468.30 $669.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif3b ( NM_133916.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598677.1 Mus musculus eukaryotic translation initiation factor 3, subunit B (Eif3b), mRNA.

Price & Availability↑

CloneID	OMu18455
Clone ID Related Accession (Same CDS sequence)	NM_133916.2
Accession Version	NM_133916.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 3 subunit B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC131670.5. On or before Sep 5, 2008 this sequence version replaced XM_001476110.1, NM_133916.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK033722.1, AK167618.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGACG CTGAGAACGT GGCGGTGCCC GAGGCGGCCG AGGAGCGGGC TGAGCCCGCG 
AGGCAGCAGC CGGCCTCCGA GTCGCCGCCG ACGGACGAGG CGGCAGGGTC TGGGGGGTCC 
GAAGTGGGGC AGACGGAAGA CGCCGAAGAA GACGCCGAGG CCGGACCGGA GCCCGAAGTG 
AGGGCCAAGC CGGCGGCCCA ATCCGAAGAG GAAACGGCGA CGAGTCCGGC CGCCTCGCCC 
ACGCCGCAGT CGGCGGAGCG GTCCCCGTCG CAGGAGCCCT CTGCTCCCGG GAAGGCAGAG 
GCCGTTGGCG AGCAGGCCCG GGGGCACCCC TCGGCTGGAG CGGAGGAGGA GGGCGGGTCT 
GATGGGAGCG CGGCTGAGGC GGAGCCGCGG GCTCTGGAGA ACGGAGAGGC AGATGAGCCC 
TCCTTCAGCG ACCCCGAGGA TTTCGTAGAC GACGTGAGCG AGGAAGAACT ACTTGGTGAT 
GTACTCAAAG ATCGGCCTCA GGAAGCGGAC GGGATTGACT CGGTGATTGT TGTAGACAAC 
GTCCCTCAGG TGGGGCCAGA CCGACTTGAG AAACTCAAAA ATGTCATCCA CAAGATCTTC 
TCCAAGTTTG GGAAAATCAT AAATGACTAT TACCCTGAGG AGGACGGAAA GACGAAAGGG 
TACATCTTTC TGGAGTACGC TTCTCCCGCC CATGCTGTGG ATGCTGTGAA AAACGCCGAT 
GGCTACAAGC TGGACAAGCA GCACACGTTC CGGGTCAACC TCTTCACCGA CTTTGACAAG 
TACATGACGA TCAGCGATGA GTGGGACATT CCAGAGAAGC AGCCTTTCAA AGACCTGGGC 
AATTTGCGTT ACTGGCTGGA AGAGGCAGAG TGTAGAGATC AGTACAGTGT GATTTTTGAG 
AGCGGAGACC GGACGTCCAT CTTCTGGAAT GACGTCAAGG ACCCAGTCTC AATTGAAGAA 
AGAGCGAGAT GGACAGAGAC GTACGTGCGC TGGTCCCCTA AGGGTACCTA CCTGGCCACT 
TTCCATCAGC GGGGTATCGC CCTCTGGGGA GGGGACAAGT TCAAGCAGAT TCAGAGGTTC 
AGCCACCAAG GCGTGCAGCT CATCGACTTC TCTCCGTGTG AAAGATACTT GGTAACGTTC 
AGCCCTCTGA TGGACACTCA GGATGACCCT CAGGCCATCA TCATCTGGGA CATCCTCACG 
GGCCATAAGA AGAGAGGTTT TCACTGCGAA AGCTCAGCCC ACTGGCCCAT CTTCAAGTGG 
AGCCATGATG GCAAATTCTT TGCAAGAATG ACCCTGGATA CTCTTAGCAT CTATGAAACA 
CCTTCCATGG GCCTTTTGGA CAAGAAGAGT TTGAAGATCT CTGGAATTAA AGACTTTTCT 
TGGTCTCCGG GTGGTAACAT CATTGCTTTT TGGGTGCCTG AAGACAAAGA TATTCCAGCC 
AGGGTGACCC TGATGCAGCT CCCCACCAGA CAGGAGATCC GAGTGAGGAA TTTGTTCAAT 
GTGGTTGATT GCAAGCTGCA CTGGCAGAAA AATGGAGATT ACCTATGTGT AAAAGTGGAC 
AGGACTCCGA AAGGCACACA GGGAGTTGTC ACAAATTTTG AAATATTCCG AATGAGGGAG 
AAGCAGGTAC CTGTTGATGT TGTTGAGATG AAAGAAACCA TCATAGCCTT TGCCTGGGAA 
CCCAATGGCA GTAAGTTTGC CGTGCTTCAT GGTGAGGCCC CTCGGATCTC TGTCTCCTTC 
TACCACGTGA AGAGCAACGG GAAGATTGAA CTCATCAAGA TGTTTGACAA GCAGCAAGCC 
AACACCATCT TCTGGAGTCC CCAGGGGCAG TTCGTGGTGC TGGCCGGGCT GAGGAGCATG 
AACGGTGCCT TGGCGTTTGT CGACACTTCA GACTGCACCG TCATGAACAT TGCAGAGCAC 
TACATGGCCT CCGATGTTGA ATGGGACCCA ACTGGCCGCT ACGTGGTTAC CTCTGTGTCG 
TGGTGGAGCC ACAAGGTGGA CAATGCTTAC TGGCTGTGGA CCTTCCAAGG TCGCCTTCTG 
CAGAAGAACA ACAAGGACCG CTTCTGCCAG CTGCTCTGGA GACCAAGGCC CCCAACACTC 
CTCAGCCAGG ATCAGATAAA GCAAATTAAA AAGGATCTGA AGAAGTACTC CAAGATCTTT 
GAGCAGAAGG ATCGCTTGAG CCAGTCCAAA GCTTCAAAGG AACTGGTGGA AAGAAGGCGG 
ACCATGATGG AGGACTTCCG GCAATACCGG AAAATGGCCC AGGAACTCTA CATGAAGCAG 
AAGAACGAGC GTCTAGAGCT ACGAGGAGGG GTGGACACTG ACGAGCTGGA CAGCAACGTG 
GATGACTGGG AGGAAGAGAC CATTGAGTTT TTTGTCACCG AGGAAGTCAT TCCTCTGGGA 
AGTCAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598677.1
CDS	57..2468
Translation	MQDAENVAVPEAAEERAEPARQQPASESPPTDEAAGSGGSEVGQTEDAEEDAEAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAGAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE

Target ORF information:

RefSeq Version	NM_133916.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 3, subunit B (Eif3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133916.2

ORF Insert Sequence:

ATGCAGGACG CTGAGAACGT GGCGGTGCCC GAGGCGGCCG AGGAGCGGGC TGAGCCCGCG 
AGGCAGCAGC CGGCCTCCGA GTCGCCGCCG ACGGACGAGG CGGCAGGGTC TGGGGGGTCC 
GAAGTGGGGC AGACGGAAGA CGCCGAAGAA GACGCCGAGG CCGGACCGGA GCCCGAAGTG 
AGGGCCAAGC CGGCGGCCCA ATCCGAAGAG GAAACGGCGA CGAGTCCGGC CGCCTCGCCC 
ACGCCGCAGT CGGCGGAGCG GTCCCCGTCG CAGGAGCCCT CTGCTCCCGG GAAGGCAGAG 
GCCGTTGGCG AGCAGGCCCG GGGGCACCCC TCGGCTGGAG CGGAGGAGGA GGGCGGGTCT 
GATGGGAGCG CGGCTGAGGC GGAGCCGCGG GCTCTGGAGA ACGGAGAGGC AGATGAGCCC 
TCCTTCAGCG ACCCCGAGGA TTTCGTAGAC GACGTGAGCG AGGAAGAACT ACTTGGTGAT 
GTACTCAAAG ATCGGCCTCA GGAAGCGGAC GGGATTGACT CGGTGATTGT TGTAGACAAC 
GTCCCTCAGG TGGGGCCAGA CCGACTTGAG AAACTCAAAA ATGTCATCCA CAAGATCTTC 
TCCAAGTTTG GGAAAATCAT AAATGACTAT TACCCTGAGG AGGACGGAAA GACGAAAGGG 
TACATCTTTC TGGAGTACGC TTCTCCCGCC CATGCTGTGG ATGCTGTGAA AAACGCCGAT 
GGCTACAAGC TGGACAAGCA GCACACGTTC CGGGTCAACC TCTTCACCGA CTTTGACAAG 
TACATGACGA TCAGCGATGA GTGGGACATT CCAGAGAAGC AGCCTTTCAA AGACCTGGGC 
AATTTGCGTT ACTGGCTGGA AGAGGCAGAG TGTAGAGATC AGTACAGTGT GATTTTTGAG 
AGCGGAGACC GGACGTCCAT CTTCTGGAAT GACGTCAAGG ACCCAGTCTC AATTGAAGAA 
AGAGCGAGAT GGACAGAGAC GTACGTGCGC TGGTCCCCTA AGGGTACCTA CCTGGCCACT 
TTCCATCAGC GGGGTATCGC CCTCTGGGGA GGGGACAAGT TCAAGCAGAT TCAGAGGTTC 
AGCCACCAAG GCGTGCAGCT CATCGACTTC TCTCCGTGTG AAAGATACTT GGTAACGTTC 
AGCCCTCTGA TGGACACTCA GGATGACCCT CAGGCCATCA TCATCTGGGA CATCCTCACG 
GGCCATAAGA AGAGAGGTTT TCACTGCGAA AGCTCAGCCC ACTGGCCCAT CTTCAAGTGG 
AGCCATGATG GCAAATTCTT TGCAAGAATG ACCCTGGATA CTCTTAGCAT CTATGAAACA 
CCTTCCATGG GCCTTTTGGA CAAGAAGAGT TTGAAGATCT CTGGAATTAA AGACTTTTCT 
TGGTCTCCGG GTGGTAACAT CATTGCTTTT TGGGTGCCTG AAGACAAAGA TATTCCAGCC 
AGGGTGACCC TGATGCAGCT CCCCACCAGA CAGGAGATCC GAGTGAGGAA TTTGTTCAAT 
GTGGTTGATT GCAAGCTGCA CTGGCAGAAA AATGGAGATT ACCTATGTGT AAAAGTGGAC 
AGGACTCCGA AAGGCACACA GGGAGTTGTC ACAAATTTTG AAATATTCCG AATGAGGGAG 
AAGCAGGTAC CTGTTGATGT TGTTGAGATG AAAGAAACCA TCATAGCCTT TGCCTGGGAA 
CCCAATGGCA GTAAGTTTGC CGTGCTTCAT GGTGAGGCCC CTCGGATCTC TGTCTCCTTC 
TACCACGTGA AGAGCAACGG GAAGATTGAA CTCATCAAGA TGTTTGACAA GCAGCAAGCC 
AACACCATCT TCTGGAGTCC CCAGGGGCAG TTCGTGGTGC TGGCCGGGCT GAGGAGCATG 
AACGGTGCCT TGGCGTTTGT CGACACTTCA GACTGCACCG TCATGAACAT TGCAGAGCAC 
TACATGGCCT CCGATGTTGA ATGGGACCCA ACTGGCCGCT ACGTGGTTAC CTCTGTGTCG 
TGGTGGAGCC ACAAGGTGGA CAATGCTTAC TGGCTGTGGA CCTTCCAAGG TCGCCTTCTG 
CAGAAGAACA ACAAGGACCG CTTCTGCCAG CTGCTCTGGA GACCAAGGCC CCCAACACTC 
CTCAGCCAGG ATCAGATAAA GCAAATTAAA AAGGATCTGA AGAAGTACTC CAAGATCTTT 
GAGCAGAAGG ATCGCTTGAG CCAGTCCAAA GCTTCAAAGG AACTGGTGGA AAGAAGGCGG 
ACCATGATGG AGGACTTCCG GCAATACCGG AAAATGGCCC AGGAACTCTA CATGAAGCAG 
AAGAACGAGC GTCTAGAGCT ACGAGGAGGG GTGGACACTG ACGAGCTGGA CAGCAACGTG 
GATGACTGGG AGGAAGAGAC CATTGAGTTT TTTGTCACCG AGGAAGTCAT TCCTCTGGGA 
AGTCAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Combination of piR-823 and Eukaryotic Initiation Factor 3 B (EIF3B) Activates Hepatic Stellate Cells via Upregulating TGF-β1 in Liver Fibrogenesis.
Medical science monitor : international medical journal of experimental and clinical research249151-9165(2018 Dec)
Tang X,Xie X,Wang X,Wang Y,Jiang X,Jiang H

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
The Journal of biological chemistry288(42)30087-93(2013 Oct)
Zeng L,Wan Y,Li D,Wu J,Shao M,Chen J,Hui L,Ji H,Zhu X

Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.
BMC genomics13411(2012 Aug)
Nedelko T,Kollmus H,Klawonn F,Spijker S,Lu L,Heßman M,Alberts R,Williams RW,Schughart K

Reconstitution reveals the functional core of mammalian eIF3.
The EMBO journal26(14)3373-83(2007 Jul)
Masutani M,Sonenberg N,Yokoyama S,Imataka H

A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system.
Development genes and evolution207(5)330-339(1997 Nov)
Neidhardt LM,Kispert A,Herrmann BG

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Eif3b cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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