Ckap4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ckap4
Entrez Gene ID	216197
Full Name	cytoskeleton-associated protein 4
Synonyms	5630400A09Rik,CLIMP-63,P63
General protein information	Preferred Names cytoskeleton-associated protein 4 Names cytoskeleton-associated protein 4 63 kDa membrane protein 63-kDa cytoskeleton-linking membrane protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_175451.1	NP_780660.1	cytoskeleton-associated protein 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	CKAP4	NP_006816.2
Mus musculus (house mouse)	Ckap4	NP_780660.1
Canis lupus familiaris (dog)	CKAP4	XP_538416.2
Gallus gallus (chicken)	CKAP4	XP_416309.4
Pan troglodytes (chimpanzee)	CKAP4	XP_001161127.2
Macaca mulatta (Rhesus monkey)	LOC702779	XP_001091079.2
Rattus norvegicus (Norway rat)	Ckap4	NP_001102210.1
Xenopus tropicalis (tropical clawed frog)	ckap4	NP_001072418.1
Bos taurus (cattle)	CKAP4	XP_002687704.3

Gene Ontology
Bibliography

Related articles in PubMed

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation.
Gladka MM, Molenaar B, de Ruiter H, van der Elst S, Tsui H, Versteeg D, Lacraz GPA, Huibers MMH, van Oudenaarden A, van Rooij E
Circulation138(2)166-180(2018 07)

Triadin and CLIMP-63 form a link between triads and microtubules in muscle cells.
Osseni A, Sébastien M, Sarrault O, Baudet M, Couté Y, Fauré J, Fourest-Lieuvin A, Marty I
Journal of cell science129(20)3744-3755(2016 10)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.
Ferone G, Mollo MR, Thomason HA, Antonini D, Zhou H, Ambrosio R, De Rosa L, Salvatore D, Getsios S, van Bokhoven H, Dixon J, Missero C
Human molecular genetics22(3)531-43(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ckap4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ckap4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14601	NM_175451.1 Latest version!	Mus musculus cytoskeleton-associated protein 4 (Ckap4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ckap4 ( NM_175451.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780660.1 Mus musculus cytoskeleton-associated protein 4 (Ckap4), mRNA.

Price & Availability↑

CloneID	OMu14601
Clone ID Related Accession (Same CDS sequence)	NM_175451.1
Accession Version	NM_175451.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569254400000
Organism	Mus musculus(house mouse)
Product	cytoskeleton-associated protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB620334.1, BE647088.1, AK030708.1 and BB033173.1. On May 17, 2005 this sequence version replaced XM_125808.5. ##Evidence-Data-START## Transcript exon combination :: AK030708.1, BC025522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCTCGG CCAAACAAAG GGGCTCCAAG GGCGGCCACG GCGCCGCGAG CCCCTCGGAC 
AAGGGCGCCC ACCCGTCGGG CGGCGCGGAT GACGTGGCGA AGAAGCCGCC GGCGGCGCCG 
CAGCAGCCGC AGCCTCCCGC GCCGCACCCG CCGCAGCACC CGCAGAACCA GGCGCACCGG 
GGCGGCCACC GCGGCCGGTC CTCAGCCGCC ACCGCCAACG CGTCCTCCGC GTCCTGCTCG 
CGCAGGCTTG GCCGGGTGCT CAACTTTCTC TTCTACCTCT CCCTGGTGGC GGCGGCCGCC 
TTCTCGGGCT GGTATGTCCA TCACGTCCTG GAGGAGGTCC AGCAGGTCCG GCGTGGCCAC 
CAGGACTTCT CCCGTCAGAG GGATGAGCTG GGCCAGGGCT TGCAGGGCGT CGAGCAGAAG 
GTCCAATCCC TGCAAGCCAC ATTTGGGACT TTCGAGTCCC TCCTGAGAAA CTCCCAGCAT 
AAACAGGATC TCACAGAGAA AGCCGTGAAG GAAGGGGAGA GCGAGCTCAA CCGAATTAGC 
GAAGTTCTAC AGAAGTTGCA GAATGAGATT CTCAAAGATC TGTCGGACGG GATCCACGTG 
GTGAAGGATG CCCGGGAGCG GGACTTCACG TCCCTGGAGA ACACAGTCGA GGAGCGCCTG 
ACGGAGCTTA CCAAGTCTAT CAATGACAAC ATCGCCATCT TCACTGATGT CCAGAAGAGG 
AGCCAGAAGG AGATCAATGA GGTCAAGATG AAGGTGGCCT CCCTGGAAGA ATCCAAGGGG 
GATCGCAGTC AGGACGTGAA AACTCTGAAG GACGCCGTGA AGGAGGTCCA GGCCTCCATG 
ATGTCGAGGG AGAGGGACAT TGAGGCCCTG AAGAGTTCCC TTCAGACGAT GGAGTCCGAC 
GTCTACACAG AGGTGCGGGA ACTGGTGAGC CTCAAGCAGG AGCAACAGGC GTTCAAGCAG 
GCGGCCGACT CAGAGCGCCT GGCTCTGCAG GCCCTCACGG AGAAGCTTCT GCGGTCCGAG 
GAGTCCTCCT CTCGTCTCCC AGAGGACATC CGGAGACTGG AGGAAGAGCT ACAGCAGCTG 
AAGGTCGGGG CCCATGGGTC AGAGGAAGGT GCCGTCTTCA AAGACTCCAA AGCCTTAGAG 
GAACTGCAGA GGCAGATTGA GGGCCTGGGT GCCAGGCTCC AGTATGTAGA GGACGGGGTC 
TACTCAATGC AGGTGGCTTC TGCACGCCAC ACCGAAAGCC TGGAGTCGCT CCTGTCCAAG 
AGCCAGGAGT ACGAGCAACG CCTGGCTATG CTGCAGGAGC ACGTGGGAAA CCTGGGCTCC 
TCATCTGACC TGGCCAGCAC AGTCAGGAGC CTGGGGGAGA CCCAGCTGGC GCTGTCCAGC 
GACTTGAAGG AGCTGAAGCA GAGCCTGGGT GAGCTGCCCG GTACCGTGGA GTCACTGCAG 
GAGCAAGTGC TCTCACTGCT CAGCCAGGAC CAAGCCCAGG CCGAGGGCTT GCCTCCTCAG 
GACTTCCTGG ACAGACTGTC CTCTCTAGAC AACCTGAAAT CCTCAGTGAG CCAAGTGGAG 
TCAGACTTGA AAATGCTCAG GACTGCCGTG GACAGTTTGG TGGCCTATTC CGTCAAAATC 
GAAACGAATG AGAATAACTT AGAGTCAGCC AAGGGCTTGC TGGATGACCT GCGGAACGAC 
CTGGATAGGT TGTTTCTGAA AGTTGAGAAG ATCCATGAAA AGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780660.1
CDS	23..1750
Translation	MPSAKQRGSKGGHGAASPSDKGAHPSGGADDVAKKPPAAPQQPQPPAPHPPQHPQNQAHRGGHRGRSSAATANASSASCSRRLGRVLNFLFYLSLVAAAAFSGWYVHHVLEEVQQVRRGHQDFSRQRDELGQGLQGVEQKVQSLQATFGTFESLLRNSQHKQDLTEKAVKEGESELNRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTDVQKRSQKEINEVKMKVASLEESKGDRSQDVKTLKDAVKEVQASMMSRERDIEALKSSLQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLRSEESSSRLPEDIRRLEEELQQLKVGAHGSEEGAVFKDSKALEELQRQIEGLGARLQYVEDGVYSMQVASARHTESLESLLSKSQEYEQRLAMLQEHVGNLGSSSDLASTVRSLGETQLALSSDLKELKQSLGELPGTVESLQEQVLSLLSQDQAQAEGLPPQDFLDRLSSLDNLKSSVSQVESDLKMLRTAVDSLVAYSVKIETNENNLESAKGLLDDLRNDLDRLFLKVEKIHEKI

Target ORF information:

RefSeq Version	NM_175451.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cytoskeleton-associated protein 4 (Ckap4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175451.1

ORF Insert Sequence:

ATGCCCTCGG CCAAACAAAG GGGCTCCAAG GGCGGCCACG GCGCCGCGAG CCCCTCGGAC 
AAGGGCGCCC ACCCGTCGGG CGGCGCGGAT GACGTGGCGA AGAAGCCGCC GGCGGCGCCG 
CAGCAGCCGC AGCCTCCCGC GCCGCACCCG CCGCAGCACC CGCAGAACCA GGCGCACCGG 
GGCGGCCACC GCGGCCGGTC CTCAGCCGCC ACCGCCAACG CGTCCTCCGC GTCCTGCTCG 
CGCAGGCTTG GCCGGGTGCT CAACTTTCTC TTCTACCTCT CCCTGGTGGC GGCGGCCGCC 
TTCTCGGGCT GGTATGTCCA TCACGTCCTG GAGGAGGTCC AGCAGGTCCG GCGTGGCCAC 
CAGGACTTCT CCCGTCAGAG GGATGAGCTG GGCCAGGGCT TGCAGGGCGT CGAGCAGAAG 
GTCCAATCCC TGCAAGCCAC ATTTGGGACT TTCGAGTCCC TCCTGAGAAA CTCCCAGCAT 
AAACAGGATC TCACAGAGAA AGCCGTGAAG GAAGGGGAGA GCGAGCTCAA CCGAATTAGC 
GAAGTTCTAC AGAAGTTGCA GAATGAGATT CTCAAAGATC TGTCGGACGG GATCCACGTG 
GTGAAGGATG CCCGGGAGCG GGACTTCACG TCCCTGGAGA ACACAGTCGA GGAGCGCCTG 
ACGGAGCTTA CCAAGTCTAT CAATGACAAC ATCGCCATCT TCACTGATGT CCAGAAGAGG 
AGCCAGAAGG AGATCAATGA GGTCAAGATG AAGGTGGCCT CCCTGGAAGA ATCCAAGGGG 
GATCGCAGTC AGGACGTGAA AACTCTGAAG GACGCCGTGA AGGAGGTCCA GGCCTCCATG 
ATGTCGAGGG AGAGGGACAT TGAGGCCCTG AAGAGTTCCC TTCAGACGAT GGAGTCCGAC 
GTCTACACAG AGGTGCGGGA ACTGGTGAGC CTCAAGCAGG AGCAACAGGC GTTCAAGCAG 
GCGGCCGACT CAGAGCGCCT GGCTCTGCAG GCCCTCACGG AGAAGCTTCT GCGGTCCGAG 
GAGTCCTCCT CTCGTCTCCC AGAGGACATC CGGAGACTGG AGGAAGAGCT ACAGCAGCTG 
AAGGTCGGGG CCCATGGGTC AGAGGAAGGT GCCGTCTTCA AAGACTCCAA AGCCTTAGAG 
GAACTGCAGA GGCAGATTGA GGGCCTGGGT GCCAGGCTCC AGTATGTAGA GGACGGGGTC 
TACTCAATGC AGGTGGCTTC TGCACGCCAC ACCGAAAGCC TGGAGTCGCT CCTGTCCAAG 
AGCCAGGAGT ACGAGCAACG CCTGGCTATG CTGCAGGAGC ACGTGGGAAA CCTGGGCTCC 
TCATCTGACC TGGCCAGCAC AGTCAGGAGC CTGGGGGAGA CCCAGCTGGC GCTGTCCAGC 
GACTTGAAGG AGCTGAAGCA GAGCCTGGGT GAGCTGCCCG GTACCGTGGA GTCACTGCAG 
GAGCAAGTGC TCTCACTGCT CAGCCAGGAC CAAGCCCAGG CCGAGGGCTT GCCTCCTCAG 
GACTTCCTGG ACAGACTGTC CTCTCTAGAC AACCTGAAAT CCTCAGTGAG CCAAGTGGAG 
TCAGACTTGA AAATGCTCAG GACTGCCGTG GACAGTTTGG TGGCCTATTC CGTCAAAATC 
GAAACGAATG AGAATAACTT AGAGTCAGCC AAGGGCTTGC TGGATGACCT GCGGAACGAC 
CTGGATAGGT TGTTTCTGAA AGTTGAGAAG ATCCATGAAA AGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation.
Circulation138(2)166-180(2018 07)
Gladka MM,Molenaar B,de Ruiter H,van der Elst S,Tsui H,Versteeg D,Lacraz GPA,Huibers MMH,van Oudenaarden A,van Rooij E

Triadin and CLIMP-63 form a link between triads and microtubules in muscle cells.
Journal of cell science129(20)3744-3755(2016 10)
Osseni A,Sébastien M,Sarrault O,Baudet M,Couté Y,Fauré J,Fourest-Lieuvin A,Marty I

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.
Human molecular genetics22(3)531-43(2013 Feb)
Ferone G,Mollo MR,Thomason HA,Antonini D,Zhou H,Ambrosio R,De Rosa L,Salvatore D,Getsios S,van Bokhoven H,Dixon J,Missero C

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Ckap4 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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