Lipa cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lipa
Entrez Gene ID	16889
Full Name	lysosomal acid lipase A
Synonyms	AA960673,Lal,Lip-1,Lip1
General protein information	Preferred Names lysosomal acid lipase A Names lysosomal acid lipase/cholesteryl ester hydrolase acid cholesteryl ester hydrolase cholesteryl esterase lipase A lysosomal acid lipase 1 sterol esterase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001111100.1	NP_001104570.1	lysosomal acid lipase/cholesteryl ester hydrolase precursor
NM_021460.3	NP_067435.3	lysosomal acid lipase/cholesteryl ester hydrolase precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LIPA	NP_001121077.1
Pan troglodytes (chimpanzee)	LIPA	XP_003312800.1
Caenorhabditis elegans (roundworm)	lipl-7	NP_501877.2
Saccharomyces cerevisiae (baker's yeast)	TGL1	NP_012782.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001652	XP_321444.5
Mus musculus (house mouse)	Lipa	NP_067435.3
Rattus norvegicus (Norway rat)	Lipa	NP_036864.3
Caenorhabditis elegans (roundworm)	lipl-4	NP_504662.1
Neurospora crassa	NCU02148	XP_964507.2
Macaca mulatta (Rhesus monkey)	LIPA	XP_001085160.2
Caenorhabditis elegans (roundworm)	lipl-5	NP_503184.1
Caenorhabditis elegans (roundworm)	lipl-3	NP_503233.1
Caenorhabditis elegans (roundworm)	lipl-2	NP_505527.1
Xenopus tropicalis (tropical clawed frog)	lipa	NP_001015847.2
Bos taurus (cattle)	LIPA	NP_001096793.1
Magnaporthe oryzae (rice blast fungus)	MGG_02622	XP_003721170.1
Schizosaccharomyces pombe (fission yeast)	SPCC1672.09	NP_587880.1
Gallus gallus (chicken)	LIPA	XP_421661.3
Caenorhabditis elegans (roundworm)	lipl-1	NP_506229.1
Caenorhabditis elegans (roundworm)	lipl-6	NP_504755.2
Canis lupus familiaris (dog)	LIPA	XP_005636708.1
Eremothecium gossypii	AGOS_AFR206C	NP_985753.1
Danio rerio (zebrafish)	lipf	NP_998569.1

Gene Ontology
Bibliography

Related articles in PubMed

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
Pajed L, Wagner C, Taschler U, Schreiber R, Kolleritsch S, Fawzy N, Pototschnig I, Schoiswohl G, Pusch LM, Wieser BI, Vesely P, Hoefler G, Eichmann TO, Zimmermann R, Lass A
The Journal of biological chemistry294(23)9118-9133(2019 Jun)

Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Leopold C, Duta-Mare M, Sachdev V, Goeritzer M, Maresch LK, Kolb D, Reicher H, Wagner B, Stojakovic T, Ruelicke T, Haemmerle G, Hoefler G, Sattler W, Kratky D
Biochimica et biophysica acta. Molecular and cell biology of lipids1864(4)500-511(2019 04)

LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo.
Bowden KL, Dubland JA, Chan T, Xu YH, Grabowski GA, Du H, Francis GA
Arteriosclerosis, thrombosis, and vascular biology38(5)1191-1201(2018 05)

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D
Biochimica et biophysica acta. Molecular and cell biology of lipids1863(4)467-478(2018 Apr)

CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma.
Shen ZQ, Chen YF, Chen JR, Jou YS, Wu PC, Kao CH, Wang CH, Huang YL, Chen CF, Huang TS, Shyu YC, Tsai SF, Kao LS, Tsai TF
Cell reports21(8)2198-2211(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lipa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lipa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22026	NM_021460.3 Latest version!	Mus musculus lysosomal acid lipase A (Lipa), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu22026	NM_001111100.1 Latest version!	Mus musculus lysosomal acid lipase A (Lipa), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lipa ( NM_001111100.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104570.1 Mus musculus lysosomal acid lipase A (Lipa), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu22026
Clone ID Related Accession (Same CDS sequence)	NM_001111100.1 , NM_021460.3
Accession Version	NM_001111100.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	lysosomal acid lipase/cholesteryl ester hydrolase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK164007.1, AK169567.1, BE449010.1, BE198807.1 and AA881350.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK164007.1, AK169567.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAACTCC AGGGCCTGGT GTTCGTTTTC ACCATTGGGA TCCTGCTTTC TCGGGTGCCC 
ACGGGAACTG TATCAGCTGT GGATCCTGAA GTCAACATGA ATGTGACCGA GATAATCATG 
CGCTGGGGAT ATCCTGGTGA GGAACACTCG GTCCTGACAG GAGATGGCTA TATTCTGAGT 
ATTCACCGAA TCCCTCGTGG GCGGAAGAAC CATTTTGGCA AAGGTCCCAG ACCAGTTGTG 
TATCTTCAGC ACGGCTTGCT GGCAGATTCT AGTAACTGGG TCACAAACAT TGACAACAGC 
AGCTTGGGCT TCCTCCTGGC GGATGCTGGC TTTGATGTGT GGATGGGAAA CAGCAGAGGA 
AACACCTGGT CTCTGAAGCA CAAGACTCTT TCAGTTTCTC AGGATGAGTT CTGGGCCTTC 
AGTTTTGATG AGATGGCAAA ATATGACCTA CCTGCTTCAA TTAACTACAT TTTGAATAAA 
ACTGGCCAAG AACAAATCTA TTATGTGGGT CATTCTCAAG GCTGCACCAT AGGTTTCATA 
GCTTTTTCAC AGATGCCTGA GTTGGCAAAG AAGATTAAAA TGTTTTTAGT CTTGGCTCCC 
GTGTTGTCTC TCAATTTTGC TTCAGGCCCG CTACTTCAAT TGGGACGCTT GCCAGACCCT 
CTTCTCAAGG ACATGTTTGG ACAGAAGCAA TTTCTCCCTC AGAGTGCGAT GCTGAAGTGG 
CTGAGCATTC ACGTTTGCAC CCACGTCATC ATGAAGGAGC TTTGCGCAAA CGTCTTCTTC 
CTGCTATGTG GCTTCAATGA GAAGAATTTA AATATGTCTA GAGTGGATGT GTATACAACA 
CACTGCCCTG CGGGAACTTC TGTGCAAAAC ATGTTACACT GGGGTCAGGT TTTTAAATAC 
CGTAAGCTTC AAGCTTTTGA CTGGGGAAGC AGTGAAAAGA ATTATTTTCA TTACAACCAG 
AGTTTTCCTC CCTCGTACAA CATAAAAAAC ATGCGTCTAC CCACTGCTTT GTGGAGCGGG 
GGCCGGGACT GGCTGGCAGA CATCAATGAC ATCACTATCT TACTGACTCA AATCCCCAAG 
TTGGTGTATC ACAAGAACAT TCCTGAGTGG GACCATCTGG ATTTTATCTG GGGTTTGGAT 
GCCCCCTGGA AACTGTATGA TGAAATAATC AGTCTAATGA AGAAATACCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104570.1
CDS	110..1303
Translation	MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ

Target ORF information:

RefSeq Version	NM_001111100.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysosomal acid lipase A (Lipa), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001111100.1

ORF Insert Sequence:

ATGCAACTCC AGGGCCTGGT GTTCGTTTTC ACCATTGGGA TCCTGCTTTC TCGGGTGCCC 
ACGGGAACTG TATCAGCTGT GGATCCTGAA GTCAACATGA ATGTGACCGA GATAATCATG 
CGCTGGGGAT ATCCTGGTGA GGAACACTCG GTCCTGACAG GAGATGGCTA TATTCTGAGT 
ATTCACCGAA TCCCTCGTGG GCGGAAGAAC CATTTTGGCA AAGGTCCCAG ACCAGTTGTG 
TATCTTCAGC ACGGCTTGCT GGCAGATTCT AGTAACTGGG TCACAAACAT TGACAACAGC 
AGCTTGGGCT TCCTCCTGGC GGATGCTGGC TTTGATGTGT GGATGGGAAA CAGCAGAGGA 
AACACCTGGT CTCTGAAGCA CAAGACTCTT TCAGTTTCTC AGGATGAGTT CTGGGCCTTC 
AGTTTTGATG AGATGGCAAA ATATGACCTA CCTGCTTCAA TTAACTACAT TTTGAATAAA 
ACTGGCCAAG AACAAATCTA TTATGTGGGT CATTCTCAAG GCTGCACCAT AGGTTTCATA 
GCTTTTTCAC AGATGCCTGA GTTGGCAAAG AAGATTAAAA TGTTTTTAGT CTTGGCTCCC 
GTGTTGTCTC TCAATTTTGC TTCAGGCCCG CTACTTCAAT TGGGACGCTT GCCAGACCCT 
CTTCTCAAGG ACATGTTTGG ACAGAAGCAA TTTCTCCCTC AGAGTGCGAT GCTGAAGTGG 
CTGAGCATTC ACGTTTGCAC CCACGTCATC ATGAAGGAGC TTTGCGCAAA CGTCTTCTTC 
CTGCTATGTG GCTTCAATGA GAAGAATTTA AATATGTCTA GAGTGGATGT GTATACAACA 
CACTGCCCTG CGGGAACTTC TGTGCAAAAC ATGTTACACT GGGGTCAGGT TTTTAAATAC 
CGTAAGCTTC AAGCTTTTGA CTGGGGAAGC AGTGAAAAGA ATTATTTTCA TTACAACCAG 
AGTTTTCCTC CCTCGTACAA CATAAAAAAC ATGCGTCTAC CCACTGCTTT GTGGAGCGGG 
GGCCGGGACT GGCTGGCAGA CATCAATGAC ATCACTATCT TACTGACTCA AATCCCCAAG 
TTGGTGTATC ACAAGAACAT TCCTGAGTGG GACCATCTGG ATTTTATCTG GGGTTTGGAT 
GCCCCCTGGA AACTGTATGA TGAAATAATC AGTCTAATGA AGAAATACCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lipa ( NM_021460.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067435.3 Mus musculus lysosomal acid lipase A (Lipa), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu22026
Clone ID Related Accession (Same CDS sequence)	NM_001111100.1 , NM_021460.3
Accession Version	NM_021460.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	lysosomal acid lipase/cholesteryl ester hydrolase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK164007.1, AK149791.1, AK169567.1, BE449010.1, BE198807.1 and AA881350.1. On Dec 5, 2007 this sequence version replaced NM_021460.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058564.1, AK154804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAACTCC AGGGCCTGGT GTTCGTTTTC ACCATTGGGA TCCTGCTTTC TCGGGTGCCC 
ACGGGAACTG TATCAGCTGT GGATCCTGAA GTCAACATGA ATGTGACCGA GATAATCATG 
CGCTGGGGAT ATCCTGGTGA GGAACACTCG GTCCTGACAG GAGATGGCTA TATTCTGAGT 
ATTCACCGAA TCCCTCGTGG GCGGAAGAAC CATTTTGGCA AAGGTCCCAG ACCAGTTGTG 
TATCTTCAGC ACGGCTTGCT GGCAGATTCT AGTAACTGGG TCACAAACAT TGACAACAGC 
AGCTTGGGCT TCCTCCTGGC GGATGCTGGC TTTGATGTGT GGATGGGAAA CAGCAGAGGA 
AACACCTGGT CTCTGAAGCA CAAGACTCTT TCAGTTTCTC AGGATGAGTT CTGGGCCTTC 
AGTTTTGATG AGATGGCAAA ATATGACCTA CCTGCTTCAA TTAACTACAT TTTGAATAAA 
ACTGGCCAAG AACAAATCTA TTATGTGGGT CATTCTCAAG GCTGCACCAT AGGTTTCATA 
GCTTTTTCAC AGATGCCTGA GTTGGCAAAG AAGATTAAAA TGTTTTTAGT CTTGGCTCCC 
GTGTTGTCTC TCAATTTTGC TTCAGGCCCG CTACTTCAAT TGGGACGCTT GCCAGACCCT 
CTTCTCAAGG ACATGTTTGG ACAGAAGCAA TTTCTCCCTC AGAGTGCGAT GCTGAAGTGG 
CTGAGCATTC ACGTTTGCAC CCACGTCATC ATGAAGGAGC TTTGCGCAAA CGTCTTCTTC 
CTGCTATGTG GCTTCAATGA GAAGAATTTA AATATGTCTA GAGTGGATGT GTATACAACA 
CACTGCCCTG CGGGAACTTC TGTGCAAAAC ATGTTACACT GGGGTCAGGT TTTTAAATAC 
CGTAAGCTTC AAGCTTTTGA CTGGGGAAGC AGTGAAAAGA ATTATTTTCA TTACAACCAG 
AGTTTTCCTC CCTCGTACAA CATAAAAAAC ATGCGTCTAC CCACTGCTTT GTGGAGCGGG 
GGCCGGGACT GGCTGGCAGA CATCAATGAC ATCACTATCT TACTGACTCA AATCCCCAAG 
TTGGTGTATC ACAAGAACAT TCCTGAGTGG GACCATCTGG ATTTTATCTG GGGTTTGGAT 
GCCCCCTGGA AACTGTATGA TGAAATAATC AGTCTAATGA AGAAATACCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067435.3
CDS	114..1307
Translation	MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ

Target ORF information:

RefSeq Version	NM_021460.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysosomal acid lipase A (Lipa), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021460.3

ORF Insert Sequence:

ATGCAACTCC AGGGCCTGGT GTTCGTTTTC ACCATTGGGA TCCTGCTTTC TCGGGTGCCC 
ACGGGAACTG TATCAGCTGT GGATCCTGAA GTCAACATGA ATGTGACCGA GATAATCATG 
CGCTGGGGAT ATCCTGGTGA GGAACACTCG GTCCTGACAG GAGATGGCTA TATTCTGAGT 
ATTCACCGAA TCCCTCGTGG GCGGAAGAAC CATTTTGGCA AAGGTCCCAG ACCAGTTGTG 
TATCTTCAGC ACGGCTTGCT GGCAGATTCT AGTAACTGGG TCACAAACAT TGACAACAGC 
AGCTTGGGCT TCCTCCTGGC GGATGCTGGC TTTGATGTGT GGATGGGAAA CAGCAGAGGA 
AACACCTGGT CTCTGAAGCA CAAGACTCTT TCAGTTTCTC AGGATGAGTT CTGGGCCTTC 
AGTTTTGATG AGATGGCAAA ATATGACCTA CCTGCTTCAA TTAACTACAT TTTGAATAAA 
ACTGGCCAAG AACAAATCTA TTATGTGGGT CATTCTCAAG GCTGCACCAT AGGTTTCATA 
GCTTTTTCAC AGATGCCTGA GTTGGCAAAG AAGATTAAAA TGTTTTTAGT CTTGGCTCCC 
GTGTTGTCTC TCAATTTTGC TTCAGGCCCG CTACTTCAAT TGGGACGCTT GCCAGACCCT 
CTTCTCAAGG ACATGTTTGG ACAGAAGCAA TTTCTCCCTC AGAGTGCGAT GCTGAAGTGG 
CTGAGCATTC ACGTTTGCAC CCACGTCATC ATGAAGGAGC TTTGCGCAAA CGTCTTCTTC 
CTGCTATGTG GCTTCAATGA GAAGAATTTA AATATGTCTA GAGTGGATGT GTATACAACA 
CACTGCCCTG CGGGAACTTC TGTGCAAAAC ATGTTACACT GGGGTCAGGT TTTTAAATAC 
CGTAAGCTTC AAGCTTTTGA CTGGGGAAGC AGTGAAAAGA ATTATTTTCA TTACAACCAG 
AGTTTTCCTC CCTCGTACAA CATAAAAAAC ATGCGTCTAC CCACTGCTTT GTGGAGCGGG 
GGCCGGGACT GGCTGGCAGA CATCAATGAC ATCACTATCT TACTGACTCA AATCCCCAAG 
TTGGTGTATC ACAAGAACAT TCCTGAGTGG GACCATCTGG ATTTTATCTG GGGTTTGGAT 
GCCCCCTGGA AACTGTATGA TGAAATAATC AGTCTAATGA AGAAATACCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
The Journal of biological chemistry294(23)9118-9133(2019 Jun)
Pajed L,Wagner C,Taschler U,Schreiber R,Kolleritsch S,Fawzy N,Pototschnig I,Schoiswohl G,Pusch LM,Wieser BI,Vesely P,Hoefler G,Eichmann TO,Zimmermann R,Lass A

Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Biochimica et biophysica acta. Molecular and cell biology of lipids1864(4)500-511(2019 04)
Leopold C,Duta-Mare M,Sachdev V,Goeritzer M,Maresch LK,Kolb D,Reicher H,Wagner B,Stojakovic T,Ruelicke T,Haemmerle G,Hoefler G,Sattler W,Kratky D

LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo.
Arteriosclerosis, thrombosis, and vascular biology38(5)1191-1201(2018 05)
Bowden KL,Dubland JA,Chan T,Xu YH,Grabowski GA,Du H,Francis GA

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Biochimica et biophysica acta. Molecular and cell biology of lipids1863(4)467-478(2018 Apr)
Duta-Mare M,Sachdev V,Leopold C,Kolb D,Vujic N,Korbelius M,Hofer DC,Xia W,Huber K,Auer M,Gottschalk B,Magnes C,Graier WF,Prokesch A,Radovic B,Bogner-Strauss JG,Kratky D

CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma.
Cell reports21(8)2198-2211(2017 Nov)
Shen ZQ,Chen YF,Chen JR,Jou YS,Wu PC,Kao CH,Wang CH,Huang YL,Chen CF,Huang TS,Shyu YC,Tsai SF,Kao LS,Tsai TF

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Lipa cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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