| Gene Symbol | SELENOF |
| Entrez Gene ID | 712469 |
| Full Name | selenoprotein F |
| Synonyms | SEP15 |
| Gene Type | protein-coding |
| Organism | Macaca mulatta(Rhesus monkey) |
| Summary | The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2016]. |
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SELENOF cDNA ORF clone, Macaca mulatta(Rhesus monkey)
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Gene
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Clones
gRNAs
The following SELENOF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SELENOF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMb03104 Clone ID Related Accession (Same CDS sequence) NM_001159416.2 Accession Version NM_001159416.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 498bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1575907200000 Organism Macaca mulatta(Rhesus monkey) Product selenoprotein F isoform 1 precursor Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from QNVO02000012.1, JV528708.1 and JV704574.1. On Nov 9, 2016 this sequence version replaced NM_001159416.1. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: JV704574.1, JU332145.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688315, SAMEA4688316 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481ATGGTAGCGA TGGCGGCTGG GCTGAGTGGG TGGCTGGTGC CGACGTTTGG GCTACGGTTG
TTGTTGGCGA CTGTGCTTCA AGCGGTTTCT GCTTTTGGGG CAGAGTTTTC ATCAGAGGCA
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTCTGCAGCT CTTGTGATCT TCTCGGACAG
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG
TTCCCTCAAG TCCAAGCTTT CGTTAGGAGT GATAAACCCA AATTGTTCAG AGGACTACAA
ATCAAGTATG TCCGTGGTTC AGACCCTATA TTAAAGCTTT TGGATGACAA TGGGAACATT
GCTGAAGAAC TAAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA
AAGTTGGAAC GCATATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001152888.1 CDS 261..758 Translation 
Target ORF information:
RefSeq Version NM_001159416.2 Organism Macaca mulatta(Rhesus monkey) Definition Macaca mulatta selenoprotein F (SELENOF), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001159416.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481ATGGTAGCGA TGGCGGCTGG GCTGAGTGGG TGGCTGGTGC CGACGTTTGG GCTACGGTTG
TTGTTGGCGA CTGTGCTTCA AGCGGTTTCT GCTTTTGGGG CAGAGTTTTC ATCAGAGGCA
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTCTGCAGCT CTTGTGATCT TCTCGGACAG
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG
TTCCCTCAAG TCCAAGCTTT CGTTAGGAGT GATAAACCCA AATTGTTCAG AGGACTACAA
ATCAAGTATG TCCGTGGTTC AGACCCTATA TTAAAGCTTT TGGATGACAA TGGGAACATT
GCTGAAGAAC TAAGCATTCT CAAATGGAAC ACAGACAGTG TAGAAGAATT CCTGAGTGAA
AAGTTGGAAC GCATATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMb57585 Clone ID Related Accession (Same CDS sequence) NM_001346968.1 Accession Version NM_001346968.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 357bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1575907200000 Organism Macaca mulatta(Rhesus monkey) Product selenoprotein F isoform 2 precursor Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from QNVO02000012.1, JU337415.1 and JV704574.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: JU337415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688315, SAMEA4688317 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301ATGGTAGCGA TGGCGGCTGG GCTGAGTGGG TGGCTGGTGC CGACGTTTGG GCTACGGTTG
TTGTTGGCGA CTGTGCTTCA AGCGGTTTCT GCTTTTGGGG CAGAGTTTTC ATCAGAGGCA
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTCTGCAGCT CTTGTGATCT TCTCGGACAG
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTATA TTAAAGCTTT TGGATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001333897.1 CDS 261..617 Translation
Target ORF information:
RefSeq Version NM_001346968.1 Organism Macaca mulatta(Rhesus monkey) Definition Macaca mulatta selenoprotein F (SELENOF), transcript variant 2, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001346968.1
ORF Insert Sequence:
1
61
121
181
241
301ATGGTAGCGA TGGCGGCTGG GCTGAGTGGG TGGCTGGTGC CGACGTTTGG GCTACGGTTG
TTGTTGGCGA CTGTGCTTCA AGCGGTTTCT GCTTTTGGGG CAGAGTTTTC ATCAGAGGCA
TGCAGAGAGT TAGGCTTTTC TAGCAACTTG CTCTGCAGCT CTTGTGATCT TCTCGGACAG
TTCAACCTGC TTCAGCTGGA TCCTGATTGC AGAGGATGCT GTCAGGAGGA AGCACAATTT
GAAACCAAAA AGCTGTATGC AGGAGCTATT CTTGAAGTTT GTGGATGAAA ATTGGGAAGG
TTCCCTCAAG TCCAAGTATG TCCGTGGTTC AGACCCTATA TTAAAGCTTT TGGATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Biology direct9(1)20(2014 Oct)
Zimin AV,Cornish AS,Maudhoo MD,Gibbs RM,Zhang X,Pandey S,Meehan DT,Wipfler K,Bosinger SE,Johnson ZP,Tharp GK,Marçais G,Roberts M,Ferguson B,Fox HS,Treangen T,Salzberg SL,Yorke JA,Norgren RB Jr
Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN
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