PRP1 cDNA ORF clone, Leishmania infantum JPCM5

Gene
Clones
gRNAs

Summary

Gene Symbol	PRP1
Entrez Gene ID	5071490
Full Name	pentamidine resistance protein 1
Gene Type	protein-coding
Organism	Leishmania infantum JPCM5

mRNA and Protein(s)

mRNA	Protein	Name
XM_001467402.1	XP_001467439.1	pentamidine resistance protein 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, Depledge DP, Harris D, Her Y, Herzyk P, Imamura H, Otto TD, Sanders M, Seeger K, Dujardin JC, Berriman M, Smith DF, Hertz-Fowler C, Mottram JC
Genome research21(12)2129-42(2011 Dec)

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, Quail MA, Peters N, Adlem E, Tivey A, Aslett M, Kerhornou A, Ivens A, Fraser A, Rajandream MA, Carver T, Norbertczak H, Chillingworth T, Hance Z, Jagels K, Moule S, Ormond D, Rutter S, Squares R, Whitehead S, Rabbinowitsch E, Arrowsmith C, White B, Thurston S, Bringaud F, Baldauf SL, Faulconbridge A, Jeffares D, Depledge DP, Oyola SO, Hilley JD, Brito LO, Tosi LR, Barrell B, Cruz AK, Mottram JC, Smith DF, Berriman M
Nature genetics39(7)839-47(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PRP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OLc04884	XM_001467402.1 Latest version!	Leishmania infantum JPCM5 pentamidine resistance protein 1 (PRP1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRP1 ( XM_001467402.1 ) cDNA ORF clone, Leishmania infantum JPCM5 -> XP_001467439.1 Leishmania infantum JPCM5 pentamidine resistance protein 1 (PRP1), partial mRNA.

Price & Availability↑

CloneID	OLc04884
Clone ID Related Accession (Same CDS sequence)	XM_001467402.1
Accession Version	XM_001467402.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5421bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1436889600000
Organism	Leishmania infantum JPCM5
Product	pentamidine resistance protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_009415). COMPLETENESS: incomplete on both ends.

ATGAGCAGTC AACGACCGGA GATGCCAGAA GGAGCGGCGA GTGATAGCGT CTACTCGTTC 
GGCGAGGTTA ACCGACGGTT GTGGCTTCTG CGTTCTAATT CGTTACCGAA GGGTAGCGCT 
TGTGATGATG CGTTGGTGGA CTGGGCTGCG ATACGCGGGT TGCTGGAGGA GGCTCCGGAA 
GAGCGGAGCG GCGTTTTATC GCGTTACCTG CTGCGGTGGC TGAACCCATA TGTTATGCTT 
GCGTGGAGGG AGCGGCTGGA GGAGGCGTAC ATGCCTCCAC CACAGCGGGC GCACCGCGCC 
GTGTGCTGTG GCGCTCTGCT AAGCCGCGCG TTTCGCGAGG AGGAGGTTCG CGGGGGCCGC 
GACGCGTGGC GTGCGCGCGT TGAAGCTGCG CTTCCAGTGC AGTGTGGAGC CTGCGATGAC 
CCCTCGGGGG AAAGTGAAGT GATTGGCGGC GATTATAACG GGCGATGGGG TGGCGCGCGC 
GTGGCGGCTA TCAACGAGCT GTCACGTGTG AGGTTCCGTG GTGAGGAGGG TGTCCATGGA 
CGGCTGCGGT GGGTGGGGTA CGTTCGATCG AGCGACACGC CGCACACGCT TTTGTGCGGT 
GTGGAGTGGG ACGCTGACAG CGCGTTGCCG CCGTATCGTG CGCGTGTGGC TGGTGATGCG 
GCTGATGAAG TAGTGCACGA CGGGTGCGTG CAGGGCGAGC GTCTGTTTTA CCAGGTTCAG 
GATGGGCGGG CGCGGTGCAC GTGCGAGTAC GTGCAGGATC TGGTGCCGGT TTCGACGATT 
GGAATCGCGG ATACTGGGTG CCCGCGTATG CCTCACGCTC CGTCGCTGCT TTGGGCGCTA 
CTCCGCACGT TTCGCTCCGA TCTAATGGCG ATACTGCCAC CTTCGATTGC CGGTATGATA 
TGTGAAGTGT CGACACCGTG GTTGCTGCAG CAGTTTGTGC TGTTCCTGCA GTCGAGCAAG 
GAGCGGGCGG AAGCGAGAAA AGGGCTGCTC TTCTTCTCGA TTCTTGTGAT CGTGAAGTTG 
GTGCAACCAG CGTTGATGAA CAAGGAGATG CACCGCAGTC GGCGTGTTTC GAGCCTTTTC 
CGCACCTCGA CACTCGCCCT GATTTTCGAA AAGTGTCTGA CGATATCGCC GGATGCGCTG 
TCGAGACCGG ACATGAACAC TGGTCGTGTG CTAGCGATGG CGAGCTCTGA CGTTGAGAAC 
ATCAAGGAAT TTCCCACGCG GGTGATGTTC CTGTGGATGG CGCCGACTAT GCTGACGCTG 
TACGTTGCCT ACCTCTTCGT TCTCGTGGGG CCGAGTGCCC TGGCTGCTGT CCTGGTTTTT 
GCCGCTTTAC TGCCTGTCCA AGGGGGGCTA ACGAATGCTA TGGGCGGCGC ACAAGAGAAC 
CTGTCGAGCT GCACGGATCA GCGCTTGCGT CGCACGAATG AACTGCTCTC CGGCATCCGT 
GTCGTGAAGA TGATGGGATG GGAGTCGAAG TTTGTCTCGG CGATCGAAGA TAACGCACGG 
GCCGATGAGT TGCGATTCCG ACGAAGACTG CAGATGCGTC AAGTCGGGCT GTGGGCATGC 
GTGTTCTCTA CTCCGACGTT CATGATCGCC GCTGTTCTCA CTACCTACAC CCTCAGCGGA 
CACAAGCTTG ACGCATCCGT GGTGTTCCCT CTCATCGCAG TTGTCAGTGC TATAACTTTC 
CCTGTAATGA TGCTTCCGGA GGCCTTTACG TCGCTGGCGA AGTTCATTGT GTCGACGGGG 
CGCGTCACGC AGTTCTTGGA GTGCGACGAC TCGCACATCA TCGTCGAGCA CGCGGAGCGC 
ATGCTCAACA GCACAGGGAG TGGCGGCGCT GCTTCCGGGG ACGCACCGCT GCCGAGTGCC 
GCTTCGGCCG ACCTTGCAAG GGTGCTTGTG TCAGTGCCCG CCGCGCTTCC CGTGTACGAG 
CCGCGACACG TGGGGCTGCG CCGCGTGGCG CAGAGGATAC TGTGCGCGGT GCTGCGCCGC 
CGTGTGCCGG TGGAGCTTCA GTGGCGGAGG GCGGCTGCTT CCCCTGCCAT GGGTGAAGGC 
GGTAGGAAGC CTGCGCGCGT TGCTGTGGGG AACGATGATG GCGGTGTGGC TGTTGCGGGT 
GGTGAGAACG GGCGCGGCAG TGATAGTGGC GTGGCTCTGT ACGCGATGGT GGACAGGGCT 
CTCCTGCGCG ATGTGCGCGT GTCGTTCCCG CGCGCGCAGT TGACGGTTGT TGTTGGCGCG 
ACGGGGAGCG GGAAGTCTGT GCTGCTGGCG ACGCTTTTGG GTGCGTTCCG GTTCGAGGGG 
CATGTGAGCG TAGCGAAGTC GGTAGCTTAC GTGCCGCAGC AGCCGTGGAT CATGCAGGAA 
ACGTTAGAGG CGAACATCAC GTTCTTCGAG GGCGATCGGC GCGGCGCTGC TGGTGGCGCG 
GCGGTCGATA GCAATAGCGG CTCTGCGCAG GCGTTCTCGC CTCTGAGGTG CGCTGAGCAA 
GCTGCTGGCG CTGCTGCTGT GCCACGGTGC TTCAGCTGCG GCCGTGACGC GGCGAGCGAG 
CGTCTTGCGC GCGCTGTGCG GAGCTGCCAG CTGAATGCTG ATGTGGCACT GATGGCGCGC 
GGGCTGGGGA CAGAGATCGG CGAGCGTGGC ATCAACCTGA GCGGTGGGCA GAAGGCGCGC 
GTGAGCCTTG CGCGCGCCGT GTATGCGGAC CGCGACGTGT ACCTGCTGGA CGATCCGCTG 
TCGGCGCTGG ACGCGCACGT TGGGCGGCGC GTGATGGACG AGGTTGTGCT GCGCGCGTTG 
GCGGGCAAGA CGCGCGTGCT AGCGACGCAC CAGCTGCAGG TGCTGCCGCA CGCGGACCAG 
GTCGTGGTGA TGCGCGAGGG CTGCGCCGTG TTTGCGGGCA GCTACGCTGC TTACGCTGCG 
TCGGAGTGGA AGGCGTACGT GGAGAGCGAG GAGGCCGCCG CCGCGAGCAA GAAGAGCGGG 
TGTGGCGGTG GTGATACTGT GGCGGAGTGC ACCGAGGCCA GTTCTGCGTG GTCGTCTGCG 
GTGAACGTGG AGTCGTGTGT GGGCACGCGT GAGGAGCGTG ACCACGCTCG GTGTGGCGGT 
GCCGATGGCC GCGCCAGCAA AGACGGCGGT GAGTGGGGGG AGAACGATGG CAGCCCTTTG 
CCGAGAATGC ACTGGCAGGG CTCATGGGCC AGCGAGAACT CAGAGGCGGA AGGCTGCAAC 
AATAGGGACT CTACGGTATG TAAAGGTGTT AGGCTCGCAA GCAGGTCTAA GGCCGCGCCG 
CGCACGGCGA AGGGCTCATC TGGGCTGTCT ACGGGTGAGG ATGCAGCGGA CGGCGGCGAC 
CTGATGACTG CGGAGGAGAA GGAGACAGGG CACACACCGT GGAGTGTGTA CCGTGCCTAC 
TTTGAGGCGG GCGGGGGCGT CCCGGTCGCA ATTCAAATTG TGCTGCGCTA CTTCGTTAGC 
GAAGCGCTCT CGACAGGCTC CAGCGTTTGG CTGACGCTGT GGTCAGTGAA CTACTTTGGT 
TCTTCTCTCT CTACCAACGA ACAGCTTGGC GTGTATCTTG GACTCGTCTT TGTGGTTGCT 
GTCACAGTGT CTGCCAACGA CCTGTTTATT TTTCAGTTCG CTCGCCGCGC TGCCTGCCGC 
TTGCACGCCA TACTCTTGTA CACGGTGAGC TCAGCCACGC TGACGTTTTT TGACCGCACA 
CCACTGGGTC GCATTGTCAA CCGGTTCAGC AGGGACGTGC ACGTCCTTGA CGATGAGCTG 
CCGGCGAACG TGATTCCCTT TTTGGGCATT ACGGGATATG TCATGACGTC TTTAGCAGTG 
ACGCTATACG CTTCACCGCT TAGTGTGGTC GTGGTGCTGC TAGCGGCTTA CGCTTTTGTG 
CTCCTGCTCA AGTTCTACGC GACAGTGGTG CGTGAGGTGC GACGGCGCAG CAGTGTGGGG 
CAGTCTCCGT TGCTCTCGCT GCTGGAGGAG GTGGTGCACG GGCGTGCGAC GATCGCTGCA 
TACGACAAGT CGCACGTGCT ATTCGCGGAG GCGCTCCTGC GGCTGGACCT TGTGTACAGC 
TGCACCTACG TGGAGAAGGT TATGACGTTG TGGCTCGCTA TCCGAATCGA GTACATTGCG 
TCATTGGCCG TTATTGCTGT GGGGCTGATC GGCGTTGTGG AGAAGCTGGT AGAGGCGTCG 
CCGGCGCTGC CGGAGGCGCG CGTGGGCCTG ATCTCGCTGA GCCTCACCAT GTGCCTCGAT 
CTCAGCTGGT CGCTATCTGC ACTCCTAGAC CTTGCTGCCG CTGTCGAGGC GAGCATGAAC 
AGTGTGCAGC GCGTTTGCCA CTACATTGAT CACGTGCCGC AGGAAGCGGC GCTCCTGGAG 
CCGCGGGACG CGTATGTGGC GCGCGCTGTG GCAGCGAGTG GCGGCAGCCG CAGGGGAGGA 
GGCGAGAGCT CCAGAAGTGC GAGCGACATC GTTGTGGCTG CCGGCGGTGA TGACGACGAG 
GCCGCGCCTG CGCGACAGGG TGTTGCGGCA AGGAGCGGCG CGTTTGGCGC GCTGAGGCTG 
GAGCACGTGG ACCTGCGGTA CCGGCCAGGG CTGCCGCTGG TGCTGCGCGA TGTCTGCTTT 
GCGATCGCCC CTGGGCAGAA GGTGGGCGTT GTGGGGCGGA CGGGGAGCGG GAAGTCGACG 
CTGCTGCTGG CCTTCCTGCG GCTGGTGGAG GTAAGCGGCG GTCGCATGCT CGTCTGCGGG 
CGCGACGCGC GGACGTACAC GCTTCCCGCT CTGCGGCGGC TGTTTTCCAT GATCCCGCAG 
GATCCCGTGC TGTTCGATGG CACGGTGCGC AGCAACGTGG ATCCGTTCGG CGACGCGACG 
GACGAGGAGG TGCGTGCCGC GCTGGTGTCT GTGGGGTTTG TGGGGGTGGG CGGCAGCTCA 
GCTACCTTTC CTACAGCTTC TGGACTGCCG AGCGCTGCAT CTGACAGCAT GCCTGCGTTG 
GACACTGTGG TGCAGGGGGG CGGGTCGAAC TTCAGCGTTG GGCAGCGCCA GCTGCTGTGC 
TTAGCGCGCG CGCTGCTGAA GAAGGGGAGT GCATTCATCC TGATGGACGA GGCGACGGCG 
AACGTGGACG CACAGCTGGA CCAGACGGTG CAGCGTATTG TGGCGGAGCA GTTTGGCGCG 
TACACGGTGG TGACGATCGC GCACCGTCTG CACACGGTGG CGGCGTACGA CGTAGTGCTT 
GTGATGGCGC GCGGGCGTGT GGTGGAGATG GGGAAGCCGC GGGCGCTGCT GGAGCGTCGC 
GACTCCGTGT TCTACGGTAT GGTAGCGCAG AGCGCAGCGG TGGCTGATTC CCGTGAGGGC 
TTGTCGCGGG AGGATGCCGA GGGTGCGGCC AGTGGTGCGC GTTCGCGTGG CGTCAGTGAC 
GGGGGCGCTG AGCTGGGGGC GGCTGGGCGC GAACACCGCG TGGAGGCCGC GGTCGCGTCG 
CTCCTGCGTC AGTGCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001467439.1
CDS	1..5421
Translation	MSSQRPEMPEGAASDSVYSFGEVNRRLWLLRSNSLPKGSACDDALVDWAAIRGLLEEAPEERSGVLSRYLLRWLNPYVMLAWRERLEEAYMPPPQRAHRAVCCGALLSRAFREEEVRGGRDAWRARVEAALPVQCGACDDPSGESEVIGGDYNGRWGGARVAAINELSRVRFRGEEGVHGRLRWVGYVRSSDTPHTLLCGVEWDADSALPPYRARVAGDAADEVVHDGCVQGERLFYQVQDGRARCTCEYVQDLVPVSTIGIADTGCPRMPHAPSLLWALLRTFRSDLMAILPPSIAGMICEVSTPWLLQQFVLFLQSSKERAEARKGLLFFSILVIVKLVQPALMNKEMHRSRRVSSLFRTSTLALIFEKCLTISPDALSRPDMNTGRVLAMASSDVENIKEFPTRVMFLWMAPTMLTLYVAYLFVLVGPSALAAVLVFAALLPVQGGLTNAMGGAQENLSSCTDQRLRRTNELLSGIRVVKMMGWESKFVSAIEDNARADELRFRRRLQMRQVGLWACVFSTPTFMIAAVLTTYTLSGHKLDASVVFPLIAVVSAITFPVMMLPEAFTSLAKFIVSTGRVTQFLECDDSHIIVEHAERMLNSTGSGGAASGDAPLPSAASADLARVLVSVPAALPVYEPRHVGLRRVAQRILCAVLRRRVPVELQWRRAAASPAMGEGGRKPARVAVGNDDGGVAVAGGENGRGSDSGVALYAMVDRALLRDVRVSFPRAQLTVVVGATGSGKSVLLATLLGAFRFEGHVSVAKSVAYVPQQPWIMQETLEANITFFEGDRRGAAGGAAVDSNSGSAQAFSPLRCAEQAAGAAAVPRCFSCGRDAASERLARAVRSCQLNADVALMARGLGTEIGERGINLSGGQKARVSLARAVYADRDVYLLDDPLSALDAHVGRRVMDEVVLRALAGKTRVLATHQLQVLPHADQVVVMREGCAVFAGSYAAYAASEWKAYVESEEAAAASKKSGCGGGDTVAECTEASSAWSSAVNVESCVGTREERDHARCGGADGRASKDGGEWGENDGSPLPRMHWQGSWASENSEAEGCNNRDSTVCKGVRLASRSKAAPRTAKGSSGLSTGEDAADGGDLMTAEEKETGHTPWSVYRAYFEAGGGVPVAIQIVLRYFVSEALSTGSSVWLTLWSVNYFGSSLSTNEQLGVYLGLVFVVAVTVSANDLFIFQFARRAACRLHAILLYTVSSATLTFFDRTPLGRIVNRFSRDVHVLDDELPANVIPFLGITGYVMTSLAVTLYASPLSVVVVLLAAYAFVLLLKFYATVVREVRRRSSVGQSPLLSLLEEVVHGRATIAAYDKSHVLFAEALLRLDLVYSCTYVEKVMTLWLAIRIEYIASLAVIAVGLIGVVEKLVEASPALPEARVGLISLSLTMCLDLSWSLSALLDLAAAVEASMNSVQRVCHYIDHVPQEAALLEPRDAYVARAVAASGGSRRGGGESSRSASDIVVAAGGDDDEAAPARQGVAARSGAFGALRLEHVDLRYRPGLPLVLRDVCFAIAPGQKVGVVGRTGSGKSTLLLAFLRLVEVSGGRMLVCGRDARTYTLPALRRLFSMIPQDPVLFDGTVRSNVDPFGDATDEEVRAALVSVGFVGVGGSSATFPTASGLPSAASDSMPALDTVVQGGGSNFSVGQRQLLCLARALLKKGSAFILMDEATANVDAQLDQTVQRIVAEQFGAYTVVTIAHRLHTVAAYDVVLVMARGRVVEMGKPRALLERRDSVFYGMVAQSAAVADSREGLSREDAEGAASGARSRGVSDGGAELGAAGREHRVEAAVASLLRQCK

Target ORF information:

RefSeq Version	XM_001467402.1
Organism	Leishmania infantum JPCM5
Definition	Leishmania infantum JPCM5 pentamidine resistance protein 1 (PRP1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001467402.1

ORF Insert Sequence:

ATGAGCAGTC AACGACCGGA GATGCCAGAA GGAGCGGCGA GTGATAGCGT CTACTCGTTC 
GGCGAGGTTA ACCGACGGTT GTGGCTTCTG CGTTCTAATT CGTTACCGAA GGGTAGCGCT 
TGTGATGATG CGTTGGTGGA CTGGGCTGCG ATACGCGGGT TGCTGGAGGA GGCTCCGGAA 
GAGCGGAGCG GCGTTTTATC GCGTTACCTG CTGCGGTGGC TGAACCCATA TGTTATGCTT 
GCGTGGAGGG AGCGGCTGGA GGAGGCGTAC ATGCCTCCAC CACAGCGGGC GCACCGCGCC 
GTGTGCTGTG GCGCTCTGCT AAGCCGCGCG TTTCGCGAGG AGGAGGTTCG CGGGGGCCGC 
GACGCGTGGC GTGCGCGCGT TGAAGCTGCG CTTCCAGTGC AGTGTGGAGC CTGCGATGAC 
CCCTCGGGGG AAAGTGAAGT GATTGGCGGC GATTATAACG GGCGATGGGG TGGCGCGCGC 
GTGGCGGCTA TCAACGAGCT GTCACGTGTG AGGTTCCGTG GTGAGGAGGG TGTCCATGGA 
CGGCTGCGGT GGGTGGGGTA CGTTCGATCG AGCGACACGC CGCACACGCT TTTGTGCGGT 
GTGGAGTGGG ACGCTGACAG CGCGTTGCCG CCGTATCGTG CGCGTGTGGC TGGTGATGCG 
GCTGATGAAG TAGTGCACGA CGGGTGCGTG CAGGGCGAGC GTCTGTTTTA CCAGGTTCAG 
GATGGGCGGG CGCGGTGCAC GTGCGAGTAC GTGCAGGATC TGGTGCCGGT TTCGACGATT 
GGAATCGCGG ATACTGGGTG CCCGCGTATG CCTCACGCTC CGTCGCTGCT TTGGGCGCTA 
CTCCGCACGT TTCGCTCCGA TCTAATGGCG ATACTGCCAC CTTCGATTGC CGGTATGATA 
TGTGAAGTGT CGACACCGTG GTTGCTGCAG CAGTTTGTGC TGTTCCTGCA GTCGAGCAAG 
GAGCGGGCGG AAGCGAGAAA AGGGCTGCTC TTCTTCTCGA TTCTTGTGAT CGTGAAGTTG 
GTGCAACCAG CGTTGATGAA CAAGGAGATG CACCGCAGTC GGCGTGTTTC GAGCCTTTTC 
CGCACCTCGA CACTCGCCCT GATTTTCGAA AAGTGTCTGA CGATATCGCC GGATGCGCTG 
TCGAGACCGG ACATGAACAC TGGTCGTGTG CTAGCGATGG CGAGCTCTGA CGTTGAGAAC 
ATCAAGGAAT TTCCCACGCG GGTGATGTTC CTGTGGATGG CGCCGACTAT GCTGACGCTG 
TACGTTGCCT ACCTCTTCGT TCTCGTGGGG CCGAGTGCCC TGGCTGCTGT CCTGGTTTTT 
GCCGCTTTAC TGCCTGTCCA AGGGGGGCTA ACGAATGCTA TGGGCGGCGC ACAAGAGAAC 
CTGTCGAGCT GCACGGATCA GCGCTTGCGT CGCACGAATG AACTGCTCTC CGGCATCCGT 
GTCGTGAAGA TGATGGGATG GGAGTCGAAG TTTGTCTCGG CGATCGAAGA TAACGCACGG 
GCCGATGAGT TGCGATTCCG ACGAAGACTG CAGATGCGTC AAGTCGGGCT GTGGGCATGC 
GTGTTCTCTA CTCCGACGTT CATGATCGCC GCTGTTCTCA CTACCTACAC CCTCAGCGGA 
CACAAGCTTG ACGCATCCGT GGTGTTCCCT CTCATCGCAG TTGTCAGTGC TATAACTTTC 
CCTGTAATGA TGCTTCCGGA GGCCTTTACG TCGCTGGCGA AGTTCATTGT GTCGACGGGG 
CGCGTCACGC AGTTCTTGGA GTGCGACGAC TCGCACATCA TCGTCGAGCA CGCGGAGCGC 
ATGCTCAACA GCACAGGGAG TGGCGGCGCT GCTTCCGGGG ACGCACCGCT GCCGAGTGCC 
GCTTCGGCCG ACCTTGCAAG GGTGCTTGTG TCAGTGCCCG CCGCGCTTCC CGTGTACGAG 
CCGCGACACG TGGGGCTGCG CCGCGTGGCG CAGAGGATAC TGTGCGCGGT GCTGCGCCGC 
CGTGTGCCGG TGGAGCTTCA GTGGCGGAGG GCGGCTGCTT CCCCTGCCAT GGGTGAAGGC 
GGTAGGAAGC CTGCGCGCGT TGCTGTGGGG AACGATGATG GCGGTGTGGC TGTTGCGGGT 
GGTGAGAACG GGCGCGGCAG TGATAGTGGC GTGGCTCTGT ACGCGATGGT GGACAGGGCT 
CTCCTGCGCG ATGTGCGCGT GTCGTTCCCG CGCGCGCAGT TGACGGTTGT TGTTGGCGCG 
ACGGGGAGCG GGAAGTCTGT GCTGCTGGCG ACGCTTTTGG GTGCGTTCCG GTTCGAGGGG 
CATGTGAGCG TAGCGAAGTC GGTAGCTTAC GTGCCGCAGC AGCCGTGGAT CATGCAGGAA 
ACGTTAGAGG CGAACATCAC GTTCTTCGAG GGCGATCGGC GCGGCGCTGC TGGTGGCGCG 
GCGGTCGATA GCAATAGCGG CTCTGCGCAG GCGTTCTCGC CTCTGAGGTG CGCTGAGCAA 
GCTGCTGGCG CTGCTGCTGT GCCACGGTGC TTCAGCTGCG GCCGTGACGC GGCGAGCGAG 
CGTCTTGCGC GCGCTGTGCG GAGCTGCCAG CTGAATGCTG ATGTGGCACT GATGGCGCGC 
GGGCTGGGGA CAGAGATCGG CGAGCGTGGC ATCAACCTGA GCGGTGGGCA GAAGGCGCGC 
GTGAGCCTTG CGCGCGCCGT GTATGCGGAC CGCGACGTGT ACCTGCTGGA CGATCCGCTG 
TCGGCGCTGG ACGCGCACGT TGGGCGGCGC GTGATGGACG AGGTTGTGCT GCGCGCGTTG 
GCGGGCAAGA CGCGCGTGCT AGCGACGCAC CAGCTGCAGG TGCTGCCGCA CGCGGACCAG 
GTCGTGGTGA TGCGCGAGGG CTGCGCCGTG TTTGCGGGCA GCTACGCTGC TTACGCTGCG 
TCGGAGTGGA AGGCGTACGT GGAGAGCGAG GAGGCCGCCG CCGCGAGCAA GAAGAGCGGG 
TGTGGCGGTG GTGATACTGT GGCGGAGTGC ACCGAGGCCA GTTCTGCGTG GTCGTCTGCG 
GTGAACGTGG AGTCGTGTGT GGGCACGCGT GAGGAGCGTG ACCACGCTCG GTGTGGCGGT 
GCCGATGGCC GCGCCAGCAA AGACGGCGGT GAGTGGGGGG AGAACGATGG CAGCCCTTTG 
CCGAGAATGC ACTGGCAGGG CTCATGGGCC AGCGAGAACT CAGAGGCGGA AGGCTGCAAC 
AATAGGGACT CTACGGTATG TAAAGGTGTT AGGCTCGCAA GCAGGTCTAA GGCCGCGCCG 
CGCACGGCGA AGGGCTCATC TGGGCTGTCT ACGGGTGAGG ATGCAGCGGA CGGCGGCGAC 
CTGATGACTG CGGAGGAGAA GGAGACAGGG CACACACCGT GGAGTGTGTA CCGTGCCTAC 
TTTGAGGCGG GCGGGGGCGT CCCGGTCGCA ATTCAAATTG TGCTGCGCTA CTTCGTTAGC 
GAAGCGCTCT CGACAGGCTC CAGCGTTTGG CTGACGCTGT GGTCAGTGAA CTACTTTGGT 
TCTTCTCTCT CTACCAACGA ACAGCTTGGC GTGTATCTTG GACTCGTCTT TGTGGTTGCT 
GTCACAGTGT CTGCCAACGA CCTGTTTATT TTTCAGTTCG CTCGCCGCGC TGCCTGCCGC 
TTGCACGCCA TACTCTTGTA CACGGTGAGC TCAGCCACGC TGACGTTTTT TGACCGCACA 
CCACTGGGTC GCATTGTCAA CCGGTTCAGC AGGGACGTGC ACGTCCTTGA CGATGAGCTG 
CCGGCGAACG TGATTCCCTT TTTGGGCATT ACGGGATATG TCATGACGTC TTTAGCAGTG 
ACGCTATACG CTTCACCGCT TAGTGTGGTC GTGGTGCTGC TAGCGGCTTA CGCTTTTGTG 
CTCCTGCTCA AGTTCTACGC GACAGTGGTG CGTGAGGTGC GACGGCGCAG CAGTGTGGGG 
CAGTCTCCGT TGCTCTCGCT GCTGGAGGAG GTGGTGCACG GGCGTGCGAC GATCGCTGCA 
TACGACAAGT CGCACGTGCT ATTCGCGGAG GCGCTCCTGC GGCTGGACCT TGTGTACAGC 
TGCACCTACG TGGAGAAGGT TATGACGTTG TGGCTCGCTA TCCGAATCGA GTACATTGCG 
TCATTGGCCG TTATTGCTGT GGGGCTGATC GGCGTTGTGG AGAAGCTGGT AGAGGCGTCG 
CCGGCGCTGC CGGAGGCGCG CGTGGGCCTG ATCTCGCTGA GCCTCACCAT GTGCCTCGAT 
CTCAGCTGGT CGCTATCTGC ACTCCTAGAC CTTGCTGCCG CTGTCGAGGC GAGCATGAAC 
AGTGTGCAGC GCGTTTGCCA CTACATTGAT CACGTGCCGC AGGAAGCGGC GCTCCTGGAG 
CCGCGGGACG CGTATGTGGC GCGCGCTGTG GCAGCGAGTG GCGGCAGCCG CAGGGGAGGA 
GGCGAGAGCT CCAGAAGTGC GAGCGACATC GTTGTGGCTG CCGGCGGTGA TGACGACGAG 
GCCGCGCCTG CGCGACAGGG TGTTGCGGCA AGGAGCGGCG CGTTTGGCGC GCTGAGGCTG 
GAGCACGTGG ACCTGCGGTA CCGGCCAGGG CTGCCGCTGG TGCTGCGCGA TGTCTGCTTT 
GCGATCGCCC CTGGGCAGAA GGTGGGCGTT GTGGGGCGGA CGGGGAGCGG GAAGTCGACG 
CTGCTGCTGG CCTTCCTGCG GCTGGTGGAG GTAAGCGGCG GTCGCATGCT CGTCTGCGGG 
CGCGACGCGC GGACGTACAC GCTTCCCGCT CTGCGGCGGC TGTTTTCCAT GATCCCGCAG 
GATCCCGTGC TGTTCGATGG CACGGTGCGC AGCAACGTGG ATCCGTTCGG CGACGCGACG 
GACGAGGAGG TGCGTGCCGC GCTGGTGTCT GTGGGGTTTG TGGGGGTGGG CGGCAGCTCA 
GCTACCTTTC CTACAGCTTC TGGACTGCCG AGCGCTGCAT CTGACAGCAT GCCTGCGTTG 
GACACTGTGG TGCAGGGGGG CGGGTCGAAC TTCAGCGTTG GGCAGCGCCA GCTGCTGTGC 
TTAGCGCGCG CGCTGCTGAA GAAGGGGAGT GCATTCATCC TGATGGACGA GGCGACGGCG 
AACGTGGACG CACAGCTGGA CCAGACGGTG CAGCGTATTG TGGCGGAGCA GTTTGGCGCG 
TACACGGTGG TGACGATCGC GCACCGTCTG CACACGGTGG CGGCGTACGA CGTAGTGCTT 
GTGATGGCGC GCGGGCGTGT GGTGGAGATG GGGAAGCCGC GGGCGCTGCT GGAGCGTCGC 
GACTCCGTGT TCTACGGTAT GGTAGCGCAG AGCGCAGCGG TGGCTGATTC CCGTGAGGGC 
TTGTCGCGGG AGGATGCCGA GGGTGCGGCC AGTGGTGCGC GTTCGCGTGG CGTCAGTGAC 
GGGGGCGCTG AGCTGGGGGC GGCTGGGCGC GAACACCGCG TGGAGGCCGC GGTCGCGTCG 
CTCCTGCGTC AGTGCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Genome research21(12)2129-42(2011 Dec)
Rogers MB,Hilley JD,Dickens NJ,Wilkes J,Bates PA,Depledge DP,Harris D,Her Y,Herzyk P,Imamura H,Otto TD,Sanders M,Seeger K,Dujardin JC,Berriman M,Smith DF,Hertz-Fowler C,Mottram JC

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Nature genetics39(7)839-47(2007 Jul)
Peacock CS,Seeger K,Harris D,Murphy L,Ruiz JC,Quail MA,Peters N,Adlem E,Tivey A,Aslett M,Kerhornou A,Ivens A,Fraser A,Rajandream MA,Carver T,Norbertczak H,Chillingworth T,Hance Z,Jagels K,Moule S,Ormond D,Rutter S,Squares R,Whitehead S,Rabbinowitsch E,Arrowsmith C,White B,Thurston S,Bringaud F,Baldauf SL,Faulconbridge A,Jeffares D,Depledge DP,Oyola SO,Hilley JD,Brito LO,Tosi LR,Barrell B,Cruz AK,Mottram JC,Smith DF,Berriman M

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PRP1 cDNA ORF clone, Leishmania infantum JPCM5

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gRNAs

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Target ORF information:

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