AKR1B15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AKR1B15
Entrez Gene ID	441282
Full Name	aldo-keto reductase family 1 member B15
Synonyms	AKR1B10L,AKR1B10L, AK1R1B7,AKR1R1B7
General protein information	Preferred Names aldo-keto reductase family 1 member B15 Names aldo-keto reductase family 1 member B15 estradiol 17-beta-dehydrogenase AKR1B15 putative aldo-keto reductase family 1 member B15
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q33
Disorder MIM:	616336

mRNA and Protein(s)

mRNA	Protein	Name
NM_001367820.1	NP_001354749.1	aldo-keto reductase family 1 member B15 isoform a
XM_017012224.1	XP_016867713.1	aldo-keto reductase family 1 member B15 isoform X1
XM_011516241.2	XP_011514543.2	aldo-keto reductase family 1 member B15 isoform X2
NM_001080538.3	NP_001074007.2	aldo-keto reductase family 1 member B15 isoform a
NM_001367821.1	NP_001354750.1	aldo-keto reductase family 1 member B15 isoform b
XM_017012224.2	XP_016867713.1	aldo-keto reductase family 1 member B15 isoform X1
NM_001367822.1	NP_001354751.1	aldo-keto reductase family 1 member B15 isoform c
NM_001080538.2	NP_001074007.2	aldo-keto reductase family 1 member B15

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates.
Weber S, Salabei JK, Möller G, Kremmer E, Bhatnagar A, Adamski J, Barski OA
The Journal of biological chemistry290(10)6531-45(2015 Mar)

Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.
Giménez-Dejoz J, Kolář MH, Ruiz FX, Crespo I, Cousido-Siah A, Podjarny A, Barski OA, Fanfrlík J, Parés X, Farrés J, Porté S
PloS one10(7)e0134506(2015)

Identification of a role for a mouse sperm surface aldo-keto reductase (AKR1B7) and its human analogue in the detoxification of the reactive aldehyde, acrolein.
Jagoe WN, Howe K, O'Brien SC, Carroll J
Andrologia45(5)326-31(2013 Oct)

Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.
Calvo SE, Compton AG, Hershman SG, Lim SC, Lieber DS, Tucker EJ, Laskowski A, Garone C, Liu S, Jaffe DB, Christodoulou J, Fletcher JM, Bruno DL, Goldblatt J, Dimauro S, Thorburn DR, Mootha VK
Science translational medicine4(118)118ra10(2012 Jan)

Functional expression of novel human and murine AKR1B genes.
Salabei JK, Li XP, Petrash JM, Bhatnagar A, Barski OA
Chemico-biological interactions191(1-3)177-84(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AKR1B15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AKR1B15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu107485	NM_001367822.1 Latest version!	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu97263	NM_001367821.1 Latest version!	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu97263	XM_011516241.2 Latest version!	Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu23236	NM_001367820.1 Latest version!	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu23236	NM_001080538.3 Latest version!	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu23236	XM_017012224.2 Latest version!	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu23236	XM_017012224.1	Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu23236	NM_001080538.2	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AKR1B15 ( NM_001367822.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001354751.1 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 4, mRNA.

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CloneID	OHu107485
Clone ID Related Accession (Same CDS sequence)	NM_001367822.1
Accession Version	NM_001367822.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562947200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC078847.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001354751.1
CDS	163..603
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKV

Target ORF information:

RefSeq Version	NM_001367822.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001367822.1

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( NM_001367821.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001354750.1 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu97263
Clone ID Related Accession (Same CDS sequence)	XM_011516241.2 , NM_001367821.1
Accession Version	NM_001367821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562947200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC078847.2. On Dec 19, 2018 this sequence version replaced XM_011516241.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2162568, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCACGT TTGTGGAGCT CAGTACAAAA GCCAAGATGC CCATTGTGGG CCTGGGCACT 
TGGAGGTCTC TTCTCGGCAA AGTGAAAGAA GCGGTGAAGG TGGCCATTGA TGCAGAATAT 
CGCCACATTG ACTGTGCCTA TTTCTATGAG AATCAACATG AGGTGGGAGA AGCCATCCAA 
GAGAAGATCC AAGAGAAGGC TGTGATGCGG GAGGACCTGT TCATCGTCAG CAAGGTGTGG 
CCCACTTTCT TTGAGAGACC CCTTGTGAGG AAAGCCTTTG AGAAGACCCT CAAGGACCTG 
AAGCTGAGCT ATCTGGACGT CTATCTTATT CACTGGCCAC AGGGATTCAA GACTGGGGAT 
GACTTTTTCC CCAAAGATGA TAAAGGTAAT ATGATCAGTG GAAAAGGAAC GTTCTTGGAT 
GCCTGGGAGG CCATGGAGGA GCTGGTGGAC GAGGGGCTGG TGAAAGCCCT TGGGGTCTCA 
AATTTCAACC ACTTCCAGAT CGAGAGGCTC TTGAACAAAC CTGGACTGAA ATATAAACCA 
GTGACTAACC AGGTTGAGTG TCACCCATAC CTCACGCAGG AGAAACTGAT CCAGTACTGC 
CACTCCAAGG GCATCACCGT TACGGCCTAC AGCCCCCTGG GCTCTCCGGA TAGACCTTGG 
GCCAAACCTG AGGACCCTTC CCTGCTGGAG GATCCCAAGA TTAAGGAGAT TGCTGCAAAG 
CACAAAAAAA CCACAGCCCA GGTTCTGATC CGTTTCCATA TCCAGAGGAA TGTGACAGTG 
ATCCCCAAGT CTATGACACC AGCACACATT GTTGAGAACA TTCAGGTCTT TGACTTTAAA 
TTGAGTGATG AGGAGATGGC AACCATACTC AGCTTCAACA GAAACTGGAG GGCCTTTGAC 
TTCAAGGAAT TCTCTCATTT GGAGGACTTT CCCTTCGATG CAGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001354750.1
CDS	1024..1974
Translation	MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	NM_001367821.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001367821.1

ORF Insert Sequence:

ATGGCCACGT TTGTGGAGCT CAGTACAAAA GCCAAGATGC CCATTGTGGG CCTGGGCACT 
TGGAGGTCTC TTCTCGGCAA AGTGAAAGAA GCGGTGAAGG TGGCCATTGA TGCAGAATAT 
CGCCACATTG ACTGTGCCTA TTTCTATGAG AATCAACATG AGGTGGGAGA AGCCATCCAA 
GAGAAGATCC AAGAGAAGGC TGTGATGCGG GAGGACCTGT TCATCGTCAG CAAGGTGTGG 
CCCACTTTCT TTGAGAGACC CCTTGTGAGG AAAGCCTTTG AGAAGACCCT CAAGGACCTG 
AAGCTGAGCT ATCTGGACGT CTATCTTATT CACTGGCCAC AGGGATTCAA GACTGGGGAT 
GACTTTTTCC CCAAAGATGA TAAAGGTAAT ATGATCAGTG GAAAAGGAAC GTTCTTGGAT 
GCCTGGGAGG CCATGGAGGA GCTGGTGGAC GAGGGGCTGG TGAAAGCCCT TGGGGTCTCA 
AATTTCAACC ACTTCCAGAT CGAGAGGCTC TTGAACAAAC CTGGACTGAA ATATAAACCA 
GTGACTAACC AGGTTGAGTG TCACCCATAC CTCACGCAGG AGAAACTGAT CCAGTACTGC 
CACTCCAAGG GCATCACCGT TACGGCCTAC AGCCCCCTGG GCTCTCCGGA TAGACCTTGG 
GCCAAACCTG AGGACCCTTC CCTGCTGGAG GATCCCAAGA TTAAGGAGAT TGCTGCAAAG 
CACAAAAAAA CCACAGCCCA GGTTCTGATC CGTTTCCATA TCCAGAGGAA TGTGACAGTG 
ATCCCCAAGT CTATGACACC AGCACACATT GTTGAGAACA TTCAGGTCTT TGACTTTAAA 
TTGAGTGATG AGGAGATGGC AACCATACTC AGCTTCAACA GAAACTGGAG GGCCTTTGAC 
TTCAAGGAAT TCTCTCATTT GGAGGACTTT CCCTTCGATG CAGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( XM_011516241.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514543.2 Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu97263
Clone ID Related Accession (Same CDS sequence)	XM_011516241.2 , NM_001367821.1
Accession Version	XM_011516241.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516241.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACGT TTGTGGAGCT CAGTACAAAA GCCAAGATGC CCATTGTGGG CCTGGGCACT 
TGGAGGTCTC TTCTCGGCAA AGTGAAAGAA GCGGTGAAGG TGGCCATTGA TGCAGAATAT 
CGCCACATTG ACTGTGCCTA TTTCTATGAG AATCAACATG AGGTGGGAGA AGCCATCCAA 
GAGAAGATCC AAGAGAAGGC TGTGATGCGG GAGGACCTGT TCATCGTCAG CAAGGTGTGG 
CCCACTTTCT TTGAGAGACC CCTTGTGAGG AAAGCCTTTG AGAAGACCCT CAAGGACCTG 
AAGCTGAGCT ATCTGGACGT CTATCTTATT CACTGGCCAC AGGGATTCAA GACTGGGGAT 
GACTTTTTCC CCAAAGATGA TAAAGGTAAT ATGATCAGTG GAAAAGGAAC GTTCTTGGAT 
GCCTGGGAGG CCATGGAGGA GCTGGTGGAC GAGGGGCTGG TGAAAGCCCT TGGGGTCTCA 
AATTTCAACC ACTTCCAGAT CGAGAGGCTC TTGAACAAAC CTGGACTGAA ATATAAACCA 
GTGACTAACC AGGTTGAGTG TCACCCATAC CTCACGCAGG AGAAACTGAT CCAGTACTGC 
CACTCCAAGG GCATCACCGT TACGGCCTAC AGCCCCCTGG GCTCTCCGGA TAGACCTTGG 
GCCAAACCTG AGGACCCTTC CCTGCTGGAG GATCCCAAGA TTAAGGAGAT TGCTGCAAAG 
CACAAAAAAA CCACAGCCCA GGTTCTGATC CGTTTCCATA TCCAGAGGAA TGTGACAGTG 
ATCCCCAAGT CTATGACACC AGCACACATT GTTGAGAACA TTCAGGTCTT TGACTTTAAA 
TTGAGTGATG AGGAGATGGC AACCATACTC AGCTTCAACA GAAACTGGAG GGCCTTTGAC 
TTCAAGGAAT TCTCTCATTT GGAGGACTTT CCCTTCGATG CAGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514543.2
CDS	786..1736
Translation	MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	XM_011516241.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516241.2

ORF Insert Sequence:

ATGGCCACGT TTGTGGAGCT CAGTACAAAA GCCAAGATGC CCATTGTGGG CCTGGGCACT 
TGGAGGTCTC TTCTCGGCAA AGTGAAAGAA GCGGTGAAGG TGGCCATTGA TGCAGAATAT 
CGCCACATTG ACTGTGCCTA TTTCTATGAG AATCAACATG AGGTGGGAGA AGCCATCCAA 
GAGAAGATCC AAGAGAAGGC TGTGATGCGG GAGGACCTGT TCATCGTCAG CAAGGTGTGG 
CCCACTTTCT TTGAGAGACC CCTTGTGAGG AAAGCCTTTG AGAAGACCCT CAAGGACCTG 
AAGCTGAGCT ATCTGGACGT CTATCTTATT CACTGGCCAC AGGGATTCAA GACTGGGGAT 
GACTTTTTCC CCAAAGATGA TAAAGGTAAT ATGATCAGTG GAAAAGGAAC GTTCTTGGAT 
GCCTGGGAGG CCATGGAGGA GCTGGTGGAC GAGGGGCTGG TGAAAGCCCT TGGGGTCTCA 
AATTTCAACC ACTTCCAGAT CGAGAGGCTC TTGAACAAAC CTGGACTGAA ATATAAACCA 
GTGACTAACC AGGTTGAGTG TCACCCATAC CTCACGCAGG AGAAACTGAT CCAGTACTGC 
CACTCCAAGG GCATCACCGT TACGGCCTAC AGCCCCCTGG GCTCTCCGGA TAGACCTTGG 
GCCAAACCTG AGGACCCTTC CCTGCTGGAG GATCCCAAGA TTAAGGAGAT TGCTGCAAAG 
CACAAAAAAA CCACAGCCCA GGTTCTGATC CGTTTCCATA TCCAGAGGAA TGTGACAGTG 
ATCCCCAAGT CTATGACACC AGCACACATT GTTGAGAACA TTCAGGTCTT TGACTTTAAA 
TTGAGTGATG AGGAGATGGC AACCATACTC AGCTTCAACA GAAACTGGAG GGCCTTTGAC 
TTCAAGGAAT TCTCTCATTT GGAGGACTTT CCCTTCGATG CAGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( NM_001367820.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001354749.1 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23236
Clone ID Related Accession (Same CDS sequence)	NM_001367820.1 , XM_017012224.1 , NM_001080538.3 , XM_017012224.2 , NM_001080538.2
Accession Version	NM_001367820.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562947200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC078847.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: ERR279832.1334.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465410 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001354749.1
CDS	163..1197
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	NM_001367820.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001367820.1

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( NM_001080538.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074007.2 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 1, mRNA.

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CloneID	OHu23236
Clone ID Related Accession (Same CDS sequence)	NM_001367820.1 , XM_017012224.1 , NM_001080538.3 , XM_017012224.2 , NM_001080538.2
Accession Version	NM_001080538.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562947200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX335355.2 and AC078847.2. On Nov 22, 2018 this sequence version replaced NM_001080538.2. Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a). ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000457545.7/ ENSP00000389289.1 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074007.2
CDS	287..1321
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	NM_001080538.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080538.3

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( NM_001080538.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074007.2 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), mRNA.

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CloneID	OHu23236
Clone ID Related Accession (Same CDS sequence)	NM_001367820.1 , XM_017012224.1 , NM_001080538.3 , XM_017012224.2 , NM_001080538.2
Accession Version	NM_001080538.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX335355.2 and AC078847.2. On Mar 20, 2010 this sequence version replaced NM_001080538.1.

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074007.2
CDS	300..1334
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	NM_001080538.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080538.2

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( XM_017012224.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867713.1 Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu23236
Clone ID Related Accession (Same CDS sequence)	NM_001367820.1 , XM_017012224.1 , NM_001080538.3 , XM_017012224.2 , NM_001080538.2
Accession Version	XM_017012224.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867713.1
CDS	53..1087
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	XM_017012224.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1, member B15 (AKR1B15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012224.1

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B15 ( XM_017012224.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867713.1 Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu23236
Clone ID Related Accession (Same CDS sequence)	NM_001367820.1 , XM_017012224.1 , NM_001080538.3 , XM_017012224.2 , NM_001080538.2
Accession Version	XM_017012224.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	aldo-keto reductase family 1 member B15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017012224.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867713.1
CDS	53..1087
Translation	MVLQMEPQVNSTNNFHQGPLDQPVGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY

Target ORF information:

RefSeq Version	XM_017012224.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldo-keto reductase family 1 member B15 (AKR1B15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012224.2

ORF Insert Sequence:

ATGGTCTTAC AAATGGAACC CCAAGTGAAC TCAACTAACA ACTTCCACCA AGGACCCCTG 
GACCAACCCG TTGGCCCTTT GACTGGCCTA AAGAGTTCCC TTCTGAAGGA CACTACAAGT 
GCAGGGCCCC TTCTTCGCCC CTATCCAGCA TCTCTTCTCG GCAAAGTGAA AGAAGCGGTG 
AAGGTGGCCA TTGATGCAGA ATATCGCCAC ATTGACTGTG CCTATTTCTA TGAGAATCAA 
CATGAGGTGG GAGAAGCCAT CCAAGAGAAG ATCCAAGAGA AGGCTGTGAT GCGGGAGGAC 
CTGTTCATCG TCAGCAAGGT GTGGCCCACT TTCTTTGAGA GACCCCTTGT GAGGAAAGCC 
TTTGAGAAGA CCCTCAAGGA CCTGAAGCTG AGCTATCTGG ACGTCTATCT TATTCACTGG 
CCACAGGGAT TCAAGACTGG GGATGACTTT TTCCCCAAAG ATGATAAAGG TAATATGATC 
AGTGGAAAAG GAACGTTCTT GGATGCCTGG GAGGCCATGG AGGAGCTGGT GGACGAGGGG 
CTGGTGAAAG CCCTTGGGGT CTCAAATTTC AACCACTTCC AGATCGAGAG GCTCTTGAAC 
AAACCTGGAC TGAAATATAA ACCAGTGACT AACCAGGTTG AGTGTCACCC ATACCTCACG 
CAGGAGAAAC TGATCCAGTA CTGCCACTCC AAGGGCATCA CCGTTACGGC CTACAGCCCC 
CTGGGCTCTC CGGATAGACC TTGGGCCAAA CCTGAGGACC CTTCCCTGCT GGAGGATCCC 
AAGATTAAGG AGATTGCTGC AAAGCACAAA AAAACCACAG CCCAGGTTCT GATCCGTTTC 
CATATCCAGA GGAATGTGAC AGTGATCCCC AAGTCTATGA CACCAGCACA CATTGTTGAG 
AACATTCAGG TCTTTGACTT TAAATTGAGT GATGAGGAGA TGGCAACCAT ACTCAGCTTC 
AACAGAAACT GGAGGGCCTT TGACTTCAAG GAATTCTCTC ATTTGGAGGA CTTTCCCTTC 
GATGCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates.
The Journal of biological chemistry290(10)6531-45(2015 Mar)
Weber S,Salabei JK,Möller G,Kremmer E,Bhatnagar A,Adamski J,Barski OA

Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.
PloS one10(7)e0134506(2015)
Giménez-Dejoz J,Kolář MH,Ruiz FX,Crespo I,Cousido-Siah A,Podjarny A,Barski OA,Fanfrlík J,Parés X,Farrés J,Porté S

Identification of a role for a mouse sperm surface aldo-keto reductase (AKR1B7) and its human analogue in the detoxification of the reactive aldehyde, acrolein.
Andrologia45(5)326-31(2013 Oct)
Jagoe WN,Howe K,O'Brien SC,Carroll J

Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.
Science translational medicine4(118)118ra10(2012 Jan)
Calvo SE,Compton AG,Hershman SG,Lim SC,Lieber DS,Tucker EJ,Laskowski A,Garone C,Liu S,Jaffe DB,Christodoulou J,Fletcher JM,Bruno DL,Goldblatt J,Dimauro S,Thorburn DR,Mootha VK

Functional expression of novel human and murine AKR1B genes.
Chemico-biological interactions191(1-3)177-84(2011 May)
Salabei JK,Li XP,Petrash JM,Bhatnagar A,Barski OA

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AKR1B15 cDNA ORF clone, Homo sapiens(human)

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ORF Insert Sequence:

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