UPRT cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UPRT
Entrez Gene ID	139596
Full Name	uracil phosphoribosyltransferase homolog
Synonyms	FUR1,UPP
General protein information	Preferred Names uracil phosphoribosyltransferase homolog Names uracil phosphoribosyltransferase homolog RP11-311P8.3 UMP pyrophosphorylase UPRTase uracil phosphoribosyltransferase (FUR1) homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.3
Summary	This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009].
Disorder MIM:	300656

mRNA and Protein(s)

mRNA	Protein	Name
NM_001307944.1	NP_001294873.1	uracil phosphoribosyltransferase homolog isoform 2
NM_001363821.1	NP_001350750.1	uracil phosphoribosyltransferase homolog isoform 3
NM_145052.3	NP_659489.1	uracil phosphoribosyltransferase homolog isoform 1
XM_011530867.3	XP_011529169.1	uracil phosphoribosyltransferase homolog isoform X2
NM_145052.4	NP_659489.1	uracil phosphoribosyltransferase homolog isoform 1
XM_011530867.2	XP_011529169.1	uracil phosphoribosyltransferase homolog isoform X1

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	C47B2.2	NP_001252032.1
Mus musculus (house mouse)	Uprt	NP_001074658.1
Xenopus tropicalis (tropical clawed frog)	uprt	XP_002931835.1
Kluyveromyces lactis	KLLA0E22903g	XP_454985.1
Magnaporthe oryzae (rice blast fungus)	MGG_06915	XP_003709650.1
Pan troglodytes (chimpanzee)	UPRT	XP_521142.2
Canis lupus familiaris (dog)	UPRT	XP_538081.2
Saccharomyces cerevisiae (baker's yeast)	FUR1	NP_011996.2
Schizosaccharomyces pombe (fission yeast)	SPAC1B3.01c	NP_594785.1
Bos taurus (cattle)	UPRT	NP_001069713.1
Rattus norvegicus (Norway rat)	Uprt	XP_228538.3
Gallus gallus (chicken)	UPRT	NP_001026295.1
Eremothecium gossypii	AGOS_AFR052C	NP_985599.1
Neurospora crassa	NCU01446	XP_955968.1
Macaca mulatta (Rhesus monkey)	UPRT	XP_001097557.1
Danio rerio (zebrafish)	uprt	NP_996974.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007111	XP_308648.3
Homo sapiens (human)	UPRT	NP_659489.1
Drosophila melanogaster (fruit fly)	CG5537	NP_647990.1

Gene Ontology
Bibliography

Related articles in PubMed

UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan.
Ghosh AC, Shimell M, Leof ER, Haley MJ, O'Connor MB
Scientific reports513176(2015 Aug)

Specific targeting of prostate cancer cells in vitro by the suicide gene/prodrug system, uracil phosphoribosyltransferase/5-fluorouracil, under the control of prostate-specific membrane antigen promoter/enhancer.
Zhao FJ, Zhang S, Yu ZM, Xia SJ, Li H
Prostate cancer and prostatic diseases12(2)166-71(2009)

Identification and characterization of human uracil phosphoribosyltransferase (UPRTase).
Li J, Huang S, Chen J, Yang Z, Fei X, Zheng M, Ji C, Xie Y, Mao Y
Journal of human genetics52(5)415-22(2007)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following UPRT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UPRT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu106737	NM_001363821.1 Latest version!	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu75869	NM_001307944.1 Latest version!	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu75868	XM_011530867.3 Latest version!	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu23243	NM_145052.4 Latest version!	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu23243	NM_145052.3	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu75868	XM_011530867.2	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UPRT ( NM_145052.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_659489.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23243
Clone ID Related Accession (Same CDS sequence)	NM_145052.3 , NM_145052.4
Accession Version	NM_145052.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA512889.1, BC015116.1, AL590234.7, AL137013.4 and AA974609.1. This sequence is a reference standard in the RefSeqGene project. On Nov 20, 2009 this sequence version replaced NM_145052.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.265548.1, SRR1803613.111607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGCCAA ATCAATCATT 
CAGGAGTTTC CAGAGATCAC AATTTTAACT ACTGAAGTTC ATCCTGTTGC ACCTACACAT 
TTTGGACAGA AATACTTTGG AACAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659489.1
CDS	197..1126
Translation	MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD

Target ORF information:

RefSeq Version	NM_145052.3
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145052.3

ORF Insert Sequence:

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGCCAA ATCAATCATT 
CAGGAGTTTC CAGAGATCAC AATTTTAACT ACTGAAGTTC ATCCTGTTGC ACCTACACAT 
TTTGGACAGA AATACTTTGG AACAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPRT ( NM_001363821.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350750.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu106737
Clone ID Related Accession (Same CDS sequence)	NM_001363821.1
Accession Version	NM_001363821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1528905600000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL360179.8 and AL137013.4. On Jun 3, 2018 this sequence version replaced XM_024452338.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.20031.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159931 [ECO:0000348] ##Evidence-Data-END##

ATGTTTTCTG CGGATCGTTT GATCAGACTT GTTGTGGAAG AGGGATTGAA TCAGCTGCCA 
TATAAAGAAT GCATGGTGAC CACTCCAACA GGGTACAAGT ATGAAGGAGT GAAATTTGAG 
AAGGGAAATT GTGGGGTCAG CATAATGAGA AGCGGTGAGG CAATGGAACA AGGTTTACGA 
GACTGCTGTC GATCCATACG AATTGGAAAG ATCCTGATTC AGAGTGATGA GGAGACACAA 
AGAGCCAAAG TATATTATGC CAAATTCCCC CCAGACATTT ACCGGAGAAA AGTCCTTCTG 
ATGTATCCAA TTCTCAGCAC TGGAAATACT GTAATTGAAG CTGTAAAGGT TCTTATAGAA 
CATGGAGTTC AACCCAGTGT TATCATCCTA CTCAGTCTGT TCTCCACTCC TCATGGTGCC 
AAATCAATCA TTCAGGAGTT TCCAGAGATC ACAATTTTAA CTACTGAAGT TCATCCTGTT 
GCACCTACAC ATTTTGGACA GAAATACTTT GGAACAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350750.1
CDS	561..1082
Translation	MFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD

Target ORF information:

RefSeq Version	NM_001363821.1
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363821.1

ORF Insert Sequence:

ATGTTTTCTG CGGATCGTTT GATCAGACTT GTTGTGGAAG AGGGATTGAA TCAGCTGCCA 
TATAAAGAAT GCATGGTGAC CACTCCAACA GGGTACAAGT ATGAAGGAGT GAAATTTGAG 
AAGGGAAATT GTGGGGTCAG CATAATGAGA AGCGGTGAGG CAATGGAACA AGGTTTACGA 
GACTGCTGTC GATCCATACG AATTGGAAAG ATCCTGATTC AGAGTGATGA GGAGACACAA 
AGAGCCAAAG TATATTATGC CAAATTCCCC CCAGACATTT ACCGGAGAAA AGTCCTTCTG 
ATGTATCCAA TTCTCAGCAC TGGAAATACT GTAATTGAAG CTGTAAAGGT TCTTATAGAA 
CATGGAGTTC AACCCAGTGT TATCATCCTA CTCAGTCTGT TCTCCACTCC TCATGGTGCC 
AAATCAATCA TTCAGGAGTT TCCAGAGATC ACAATTTTAA CTACTGAAGT TCATCCTGTT 
GCACCTACAC ATTTTGGACA GAAATACTTT GGAACAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPRT ( NM_001307944.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294873.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu75869
Clone ID Related Accession (Same CDS sequence)	NM_001307944.1
Accession Version	NM_001307944.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527868800000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA512889.1, AK056354.1, AL590234.7, AL137013.4 and AA974609.1. On Apr 17, 2015 this sequence version replaced XM_011530866.1. Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.198598.1, SRR1660809.112515.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGAGTT CAGCATGAGG 
CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294873.1
CDS	197..1042
Translation	MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGEFSMRQ

Target ORF information:

RefSeq Version	NM_001307944.1
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307944.1

ORF Insert Sequence:

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGAGTT CAGCATGAGG 
CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPRT ( XM_011530867.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529169.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu75868
Clone ID Related Accession (Same CDS sequence)	XM_011530867.3 , XM_011530867.2
Accession Version	XM_011530867.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011530867.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGG TTTTGCCTGA GGATTTATTC CAAAAGAGCA TAGACAACTC CTGTTCTGCT 
TTTCATCGTG GCTTTCAAGG TCCTGATATG GGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529169.1
CDS	170..685
Translation	MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLVLPEDLFQKSIDNSCSAFHRGFQGPDMG

Target ORF information:

RefSeq Version	XM_011530867.3
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530867.3

ORF Insert Sequence:

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGG TTTTGCCTGA GGATTTATTC CAAAAGAGCA TAGACAACTC CTGTTCTGCT 
TTTCATCGTG GCTTTCAAGG TCCTGATATG GGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPRT ( XM_011530867.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529169.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu75868
Clone ID Related Accession (Same CDS sequence)	XM_011530867.3 , XM_011530867.2
Accession Version	XM_011530867.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011530867.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGG TTTTGCCTGA GGATTTATTC CAAAAGAGCA TAGACAACTC CTGTTCTGCT 
TTTCATCGTG GCTTTCAAGG TCCTGATATG GGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529169.1
CDS	168..683
Translation	MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLVLPEDLFQKSIDNSCSAFHRGFQGPDMG

Target ORF information:

RefSeq Version	XM_011530867.2
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530867.2

ORF Insert Sequence:

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGG TTTTGCCTGA GGATTTATTC CAAAAGAGCA TAGACAACTC CTGTTCTGCT 
TTTCATCGTG GCTTTCAAGG TCCTGATATG GGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UPRT ( NM_145052.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_659489.1 Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23243
Clone ID Related Accession (Same CDS sequence)	NM_145052.3 , NM_145052.4
Accession Version	NM_145052.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566316800000
Organism	Homo sapiens(human)
Product	uracil phosphoribosyltransferase homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA512889.1, BC015116.1, AL590234.7, AL137013.4 and AA974609.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_145052.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.66979.1, SRR1803613.111607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373383.9/ ENSP00000362481.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGCCAA ATCAATCATT 
CAGGAGTTTC CAGAGATCAC AATTTTAACT ACTGAAGTTC ATCCTGTTGC ACCTACACAT 
TTTGGACAGA AATACTTTGG AACAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659489.1
CDS	171..1100
Translation	MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD

Target ORF information:

RefSeq Version	NM_145052.4
Organism	Homo sapiens(human)
Definition	Homo sapiens uracil phosphoribosyltransferase homolog (UPRT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145052.4

ORF Insert Sequence:

ATGGCCACGG AGTTACAGTG TCCGGACTCC ATGCCCTGTC ACAACCAGCA AGTAAACTCT 
GCCTCAACCC CAAGTCCCGA GCAGCTGCGA CCTGGCGATC TGATCCTGGA CCACGCAGGG 
GGAAACAGAG CCTCCAGGGC CAAGGTGATT CTCCTCACGG GGTACGCCCA TTCTAGCCTG 
CCGGCCGAGC TGGACTCTGG GGCCTGCGGC GGCTCCAGCC TCAACTCAGA GGGCAACAGT 
GGTAGTGGTG ACAGTAGCAG CTATGACGCA CCAGCTGGCA ACTCCTTCCT AGAGGACTGC 
GAACTCTCCC GGCAGATCGG GGCGCAGCTT AAGCTGCTGC CTATGAATGA TCAGATACGG 
GAGCTACAGA CCATCATCCG TGACAAGACA GCCAGTAGAG GTGACTTCAT GTTTTCTGCG 
GATCGTTTGA TCAGACTTGT TGTGGAAGAG GGATTGAATC AGCTGCCATA TAAAGAATGC 
ATGGTGACCA CTCCAACAGG GTACAAGTAT GAAGGAGTGA AATTTGAGAA GGGAAATTGT 
GGGGTCAGCA TAATGAGAAG CGGTGAGGCA ATGGAACAAG GTTTACGAGA CTGCTGTCGA 
TCCATACGAA TTGGAAAGAT CCTGATTCAG AGTGATGAGG AGACACAAAG AGCCAAAGTA 
TATTATGCCA AATTCCCCCC AGACATTTAC CGGAGAAAAG TCCTTCTGAT GTATCCAATT 
CTCAGCACTG GAAATACTGT AATTGAAGCT GTAAAGGTTC TTATAGAACA TGGAGTTCAA 
CCCAGTGTTA TCATCCTACT CAGTCTGTTC TCCACTCCTC ATGGTGCCAA ATCAATCATT 
CAGGAGTTTC CAGAGATCAC AATTTTAACT ACTGAAGTTC ATCCTGTTGC ACCTACACAT 
TTTGGACAGA AATACTTTGG AACAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan.
Scientific reports513176(2015 Aug)
Ghosh AC,Shimell M,Leof ER,Haley MJ,O'Connor MB

Specific targeting of prostate cancer cells in vitro by the suicide gene/prodrug system, uracil phosphoribosyltransferase/5-fluorouracil, under the control of prostate-specific membrane antigen promoter/enhancer.
Prostate cancer and prostatic diseases12(2)166-71(2009)
Zhao FJ,Zhang S,Yu ZM,Xia SJ,Li H

Identification and characterization of human uracil phosphoribosyltransferase (UPRTase).
Journal of human genetics52(5)415-22(2007)
Li J,Huang S,Chen J,Yang Z,Fei X,Zheng M,Ji C,Xie Y,Mao Y

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

UPRT cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM