| Gene Symbol | ZMPSTE24 |
| Entrez Gene ID | 10269 |
| Full Name | zinc metallopeptidase STE24 |
| Synonyms | FACE-1,FACE1,HGPS,PRO1,STE24,Ste24p |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Mandibuloacral dysplasia with type B lipodystrophy, 608612 (3); Restrictive dermopathy, lethal, 275210 (3) |

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