EPOP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EPOP
Entrez Gene ID	100170841
Full Name	elongin BC and polycomb repressive complex 2 associated protein
Synonyms	C17orf96,PRR28
General protein information	Preferred Names elongin BC and polycomb repressive complex 2 associated protein Names elongin BC and Polycomb repressive complex 2-associated protein proline rich 28 proline-rich protein 28 uncharacterized protein C17orf96
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q12
Disorder MIM:	617795

mRNA and Protein(s)

mRNA	Protein	Name
NM_001130677.2	NP_001124149.1	elongin BC and Polycomb repressive complex 2-associated protein
NM_001130677.1	NP_001124149.1	elongin BC and Polycomb repressive complex 2-associated protein

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	C16H17orf96	XP_001083198.1
Rattus norvegicus (Norway rat)	LOC691153	NP_001103097.1
Canis lupus familiaris (dog)	C9H17orf96	XP_850731.2
Mus musculus (house mouse)	E130012A19Rik	NP_780541.2
Pan troglodytes (chimpanzee)	C17H17orf96	XP_003315550.1
Homo sapiens (human)	C17orf96	NP_001124149.1
Bos taurus (cattle)	C19H17orf96	XP_002695995.1

Gene Ontology
Bibliography

Related articles in PubMed

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.
Beringer M, Pisano P, Di Carlo V, Blanco E, Chammas P, Vizán P, Gutiérrez A, Aranda S, Payer B, Wierer M, Di Croce L
Molecular cell64(4)645-658(2016 11)

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
Liefke R, Karwacki-Neisius V, Shi Y
Molecular cell64(4)659-672(2016 11)

Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification.
Alekseyenko AA, Gorchakov AA, Kharchenko PV, Kuroda MI
Proceedings of the National Academy of Sciences of the United States of America111(7)2488-93(2014 Feb)

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J, Lupski JR, Nicholson C, Searle SM, Wilming L, Young SK, Abouelleil A, Allen NR, Bi W, Bloom T, Borowsky ML, Bugalter BE, Butler J, Chang JL, Chen CK, Cook A, Corum B, Cuomo CA, de Jong PJ, DeCaprio D, Dewar K, FitzGerald M, Gilbert J, Gibson R, Gnerre S, Goldstein S, Grafham DV, Grocock R, Hafez N, Hagopian DS, Hart E, Norman CH, Humphray S, Jaffe DB, Jones M, Kamal M, Khodiyar VK, LaButti K, Laird G, Lehoczky J, Liu X, Lokyitsang T, Loveland J, Lui A, Macdonald P, Major JE, Matthews L, Mauceli E, McCarroll SA, Mihalev AH, Mudge J, Nguyen C, Nicol R, O'Leary SB, Osoegawa K, Schwartz DC, Shaw-Smith C, Stankiewicz P, Steward C, Swarbreck D, Venkataraman V, Whittaker CA, Yang X, Zimmer AR, Bradley A, Hubbard T, Birren BW, Rogers J, Lander ES, Nusbaum C
Nature440(7087)1045-9(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EPOP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EPOP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16611	NM_001130677.2 Latest version!	Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu16611	NM_001130677.1	Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EPOP ( NM_001130677.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124149.1 Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.

Price & Availability↑

CloneID	OHu16611
Clone ID Related Accession (Same CDS sequence)	NM_001130677.2 , NM_001130677.1
Accession Version	NM_001130677.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571846400000
Organism	Homo sapiens(human)
Product	elongin BC and Polycomb repressive complex 2-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC006449.19. On May 17, 2019 this sequence version replaced NM_001130677.1. ##Evidence-Data-START## Transcript is intronless :: SRR1163655.464319.1, SRR6380201.138676.21 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000621654.2/ ENSP00000484710.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC TGTGCCCTGC GCCCCGCCTG GCAGTGCCGG CGTCCCCGCG AGGGTCGCCC 
TGCTCCCCCA CGCCCCGGAA GCCGTGTCGG GGGACCCAGG AATTCTCTCC GCTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAG CCCCGGGCGT CCTCTCTGGG CCCGGGGCCT 
GGGGAGCTGG CGGCGCGGTC CCCAGTGCTG CGGGGCCCTC AGGCCCCCCT GCGCCCTGGC 
GGCTGGGCCC CGGATGGCCT GAAGCACCTC TGGGCACCGA CCGGGCGGCC CGGCGTTCCT 
AACACCGCCG CCGGCGAGGA TGCGGACGTC GCAGCGTGCC CCCGCCGCGG AGAGGAGGAA 
GAGGGCGGAG GCGGTTTCCC GCACTTCGGC GTTCGCTCCT GTGCACCTCC GGGCCGCTGC 
CCTGCGCCCC CGCACCCTCG GGAATCTACG ACCAGCTTCG CCTCGGCCCC GCCTCGCCCG 
GCCCCGGGTC TCGAGCCTCA GCGTGGCCCA GCCGCCAGCC CGCCTCAGGA ACCCAGTTCC 
CGGCCTCCGT CGCCACCTGC GGGCCTCTCC ACCGAGCCCG CGGGTCCCGG GACGGCGCCG 
CGGCCGTTCC TGCCCGGCCA GCCTGCCGAA GTCGATGGAA ACCCCCCGCC GGCCGCCCCC 
GAGGCTCCAG CGGCCAGCCC CTCGACGGCC AGCCCGGCTC CGGCCGCACC CGGAGATCTC 
CGCCAGGAAC ATTTCGATCG TCTGATCCGC CGGTCGAAAC TTTGGTGTTA CGCGAAGGGC 
TTCGCCTTGG ACACTCCGAG TTTGCGCCGG GGGCCAGAGC GGCCGCCTGC GAAAGGGCCG 
GCTCGGGGAG CCGCCAAGAA ACGCCGGCTG CCGGCGCCCC CTCCGCGCAC CGCGCAGCCC 
CGCCGCCCTG CACCGACGCT CCCCACCACG AGCACCTTCA GCCTCCTCAA CTGCTTCCCC 
TGCCCCCCGG CCCTGGTGGT GGGGGAAGAC GGAGACCTAA AGCCGGCATC CTCGCTTCGC 
CTCCAGGGAG ACTCTAAGCC CCCGCCCGCC CACCCGCTGT GGAGGTGGCA GATGGGGGGT 
CCCGCTGTCC CTGAGCCCCC TGGCCTCAAA TTCTGGGGGA TCAACATGGA TGAAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124149.1
CDS	463..1602
Translation	METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES

Target ORF information:

RefSeq Version	NM_001130677.2
Organism	Homo sapiens(human)
Definition	Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130677.2

ORF Insert Sequence:

ATGGAGACCC TGTGCCCTGC GCCCCGCCTG GCAGTGCCGG CGTCCCCGCG AGGGTCGCCC 
TGCTCCCCCA CGCCCCGGAA GCCGTGTCGG GGGACCCAGG AATTCTCTCC GCTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAG CCCCGGGCGT CCTCTCTGGG CCCGGGGCCT 
GGGGAGCTGG CGGCGCGGTC CCCAGTGCTG CGGGGCCCTC AGGCCCCCCT GCGCCCTGGC 
GGCTGGGCCC CGGATGGCCT GAAGCACCTC TGGGCACCGA CCGGGCGGCC CGGCGTTCCT 
AACACCGCCG CCGGCGAGGA TGCGGACGTC GCAGCGTGCC CCCGCCGCGG AGAGGAGGAA 
GAGGGCGGAG GCGGTTTCCC GCACTTCGGC GTTCGCTCCT GTGCACCTCC GGGCCGCTGC 
CCTGCGCCCC CGCACCCTCG GGAATCTACG ACCAGCTTCG CCTCGGCCCC GCCTCGCCCG 
GCCCCGGGTC TCGAGCCTCA GCGTGGCCCA GCCGCCAGCC CGCCTCAGGA ACCCAGTTCC 
CGGCCTCCGT CGCCACCTGC GGGCCTCTCC ACCGAGCCCG CGGGTCCCGG GACGGCGCCG 
CGGCCGTTCC TGCCCGGCCA GCCTGCCGAA GTCGATGGAA ACCCCCCGCC GGCCGCCCCC 
GAGGCTCCAG CGGCCAGCCC CTCGACGGCC AGCCCGGCTC CGGCCGCACC CGGAGATCTC 
CGCCAGGAAC ATTTCGATCG TCTGATCCGC CGGTCGAAAC TTTGGTGTTA CGCGAAGGGC 
TTCGCCTTGG ACACTCCGAG TTTGCGCCGG GGGCCAGAGC GGCCGCCTGC GAAAGGGCCG 
GCTCGGGGAG CCGCCAAGAA ACGCCGGCTG CCGGCGCCCC CTCCGCGCAC CGCGCAGCCC 
CGCCGCCCTG CACCGACGCT CCCCACCACG AGCACCTTCA GCCTCCTCAA CTGCTTCCCC 
TGCCCCCCGG CCCTGGTGGT GGGGGAAGAC GGAGACCTAA AGCCGGCATC CTCGCTTCGC 
CTCCAGGGAG ACTCTAAGCC CCCGCCCGCC CACCCGCTGT GGAGGTGGCA GATGGGGGGT 
CCCGCTGTCC CTGAGCCCCC TGGCCTCAAA TTCTGGGGGA TCAACATGGA TGAAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EPOP ( NM_001130677.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124149.1 Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.

Price & Availability↑

CloneID	OHu16611
Clone ID Related Accession (Same CDS sequence)	NM_001130677.2 , NM_001130677.1
Accession Version	NM_001130677.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550332800000
Organism	Homo sapiens(human)
Product	elongin BC and Polycomb repressive complex 2-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC006449.19. COMPLETENESS: complete on the 3' end.

ATGGAGACCC TGTGCCCTGC GCCCCGCCTG GCAGTGCCGG CGTCCCCGCG AGGGTCGCCC 
TGCTCCCCCA CGCCCCGGAA GCCGTGTCGG GGGACCCAGG AATTCTCTCC GCTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAG CCCCGGGCGT CCTCTCTGGG CCCGGGGCCT 
GGGGAGCTGG CGGCGCGGTC CCCAGTGCTG CGGGGCCCTC AGGCCCCCCT GCGCCCTGGC 
GGCTGGGCCC CGGATGGCCT GAAGCACCTC TGGGCACCGA CCGGGCGGCC CGGCGTTCCT 
AACACCGCCG CCGGCGAGGA TGCGGACGTC GCAGCGTGCC CCCGCCGCGG AGAGGAGGAA 
GAGGGCGGAG GCGGTTTCCC GCACTTCGGC GTTCGCTCCT GTGCACCTCC GGGCCGCTGC 
CCTGCGCCCC CGCACCCTCG GGAATCTACG ACCAGCTTCG CCTCGGCCCC GCCTCGCCCG 
GCCCCGGGTC TCGAGCCTCA GCGTGGCCCA GCCGCCAGCC CGCCTCAGGA ACCCAGTTCC 
CGGCCTCCGT CGCCACCTGC GGGCCTCTCC ACCGAGCCCG CGGGTCCCGG GACGGCGCCG 
CGGCCGTTCC TGCCCGGCCA GCCTGCCGAA GTCGATGGAA ACCCCCCGCC GGCCGCCCCC 
GAGGCTCCAG CGGCCAGCCC CTCGACGGCC AGCCCGGCTC CGGCCGCACC CGGAGATCTC 
CGCCAGGAAC ATTTCGATCG TCTGATCCGC CGGTCGAAAC TTTGGTGTTA CGCGAAGGGC 
TTCGCCTTGG ACACTCCGAG TTTGCGCCGG GGGCCAGAGC GGCCGCCTGC GAAAGGGCCG 
GCTCGGGGAG CCGCCAAGAA ACGCCGGCTG CCGGCGCCCC CTCCGCGCAC CGCGCAGCCC 
CGCCGCCCTG CACCGACGCT CCCCACCACG AGCACCTTCA GCCTCCTCAA CTGCTTCCCC 
TGCCCCCCGG CCCTGGTGGT GGGGGAAGAC GGAGACCTAA AGCCGGCATC CTCGCTTCGC 
CTCCAGGGAG ACTCTAAGCC CCCGCCCGCC CACCCGCTGT GGAGGTGGCA GATGGGGGGT 
CCCGCTGTCC CTGAGCCCCC TGGCCTCAAA TTCTGGGGGA TCAACATGGA TGAAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124149.1
CDS	440..1579
Translation	METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES

Target ORF information:

RefSeq Version	NM_001130677.1
Organism	Homo sapiens(human)
Definition	Homo sapiens elongin BC and polycomb repressive complex 2 associated protein (EPOP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130677.1

ORF Insert Sequence:

ATGGAGACCC TGTGCCCTGC GCCCCGCCTG GCAGTGCCGG CGTCCCCGCG AGGGTCGCCC 
TGCTCCCCCA CGCCCCGGAA GCCGTGTCGG GGGACCCAGG AATTCTCTCC GCTGTGCCTG 
CGTGCCCTCG CCTTCTGCGC CCTTGCCAAG CCCCGGGCGT CCTCTCTGGG CCCGGGGCCT 
GGGGAGCTGG CGGCGCGGTC CCCAGTGCTG CGGGGCCCTC AGGCCCCCCT GCGCCCTGGC 
GGCTGGGCCC CGGATGGCCT GAAGCACCTC TGGGCACCGA CCGGGCGGCC CGGCGTTCCT 
AACACCGCCG CCGGCGAGGA TGCGGACGTC GCAGCGTGCC CCCGCCGCGG AGAGGAGGAA 
GAGGGCGGAG GCGGTTTCCC GCACTTCGGC GTTCGCTCCT GTGCACCTCC GGGCCGCTGC 
CCTGCGCCCC CGCACCCTCG GGAATCTACG ACCAGCTTCG CCTCGGCCCC GCCTCGCCCG 
GCCCCGGGTC TCGAGCCTCA GCGTGGCCCA GCCGCCAGCC CGCCTCAGGA ACCCAGTTCC 
CGGCCTCCGT CGCCACCTGC GGGCCTCTCC ACCGAGCCCG CGGGTCCCGG GACGGCGCCG 
CGGCCGTTCC TGCCCGGCCA GCCTGCCGAA GTCGATGGAA ACCCCCCGCC GGCCGCCCCC 
GAGGCTCCAG CGGCCAGCCC CTCGACGGCC AGCCCGGCTC CGGCCGCACC CGGAGATCTC 
CGCCAGGAAC ATTTCGATCG TCTGATCCGC CGGTCGAAAC TTTGGTGTTA CGCGAAGGGC 
TTCGCCTTGG ACACTCCGAG TTTGCGCCGG GGGCCAGAGC GGCCGCCTGC GAAAGGGCCG 
GCTCGGGGAG CCGCCAAGAA ACGCCGGCTG CCGGCGCCCC CTCCGCGCAC CGCGCAGCCC 
CGCCGCCCTG CACCGACGCT CCCCACCACG AGCACCTTCA GCCTCCTCAA CTGCTTCCCC 
TGCCCCCCGG CCCTGGTGGT GGGGGAAGAC GGAGACCTAA AGCCGGCATC CTCGCTTCGC 
CTCCAGGGAG ACTCTAAGCC CCCGCCCGCC CACCCGCTGT GGAGGTGGCA GATGGGGGGT 
CCCGCTGTCC CTGAGCCCCC TGGCCTCAAA TTCTGGGGGA TCAACATGGA TGAAAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.
Molecular cell64(4)645-658(2016 11)
Beringer M,Pisano P,Di Carlo V,Blanco E,Chammas P,Vizán P,Gutiérrez A,Aranda S,Payer B,Wierer M,Di Croce L

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
Molecular cell64(4)659-672(2016 11)
Liefke R,Karwacki-Neisius V,Shi Y

Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification.
Proceedings of the National Academy of Sciences of the United States of America111(7)2488-93(2014 Feb)
Alekseyenko AA,Gorchakov AA,Kharchenko PV,Kuroda MI

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Nature440(7087)1045-9(2006 Apr)
Zody MC,Garber M,Adams DJ,Sharpe T,Harrow J,Lupski JR,Nicholson C,Searle SM,Wilming L,Young SK,Abouelleil A,Allen NR,Bi W,Bloom T,Borowsky ML,Bugalter BE,Butler J,Chang JL,Chen CK,Cook A,Corum B,Cuomo CA,de Jong PJ,DeCaprio D,Dewar K,FitzGerald M,Gilbert J,Gibson R,Gnerre S,Goldstein S,Grafham DV,Grocock R,Hafez N,Hagopian DS,Hart E,Norman CH,Humphray S,Jaffe DB,Jones M,Kamal M,Khodiyar VK,LaButti K,Laird G,Lehoczky J,Liu X,Lokyitsang T,Loveland J,Lui A,Macdonald P,Major JE,Matthews L,Mauceli E,McCarroll SA,Mihalev AH,Mudge J,Nguyen C,Nicol R,O'Leary SB,Osoegawa K,Schwartz DC,Shaw-Smith C,Stankiewicz P,Steward C,Swarbreck D,Venkataraman V,Whittaker CA,Yang X,Zimmer AR,Bradley A,Hubbard T,Birren BW,Rogers J,Lander ES,Nusbaum C

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EPOP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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