mmadhc cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	mmadhc
Entrez Gene ID	402886
Full Name	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Synonyms	My011,zgc:91819
General protein information	Preferred Names methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria Names methylmalonic aciduria and homocystinuria type D protein, mitochondrial
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205594.2	NP_991157.2	methylmalonic aciduria and homocystinuria type D protein, mitochondrial

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Many genes in fish have species-specific asymmetric rates of molecular evolution.
Steinke D, Salzburger W, Braasch I, Meyer A
BMC genomics720(2006 Feb)

Hematopoietic gene expression profile in zebrafish kidney marrow.
Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT, Chen Z
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following mmadhc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mmadhc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa15067	NM_205594.2 Latest version!	Danio rerio metabolism of cobalamin associated D (mmadhc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

mmadhc ( NM_205594.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_991157.2 Danio rerio metabolism of cobalamin associated D (mmadhc), mRNA.

Price & Availability↑

CloneID	ODa15067
Clone ID Related Accession (Same CDS sequence)	NM_205594.2
Accession Version	NM_205594.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1542902400000
Organism	Danio rerio(zebrafish)
Product	methylmalonic aciduria and homocystinuria type D protein, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH437230.1, EH531169.1 and EH459674.1. On or before May 14, 2015 this sequence version replaced XM_005167549.2, NM_205594.1. ##Evidence-Data-START## Transcript exon combination :: BC074076.1, EH504992.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTG TGCTCTGCAG CAGAGCTCGA CTGGTGACGT ACCTACCAGG GCTTCATGTT 
CTAGTTCATC GTGTTGTTGG AGCAAGAAGT TTCTCTGGGG CGTCAGGATC AGATGAGCCA 
CACCTGAACA CCTCAACTCC TGACATTGCA CCAAGGACTG TGTGGCCGGA TGAGAGCATG 
GGCCCATTTG GACCTCAGGA TAAACGTTTC CAGTTGCCGG GTAATGTGGG TTTTGACTGT 
CATTTGGAGA GTCCAGTGGA GCAGAGAACC ACTTCGGTCC ATAGTGTGAT GCCAGATGTG 
CTCACTGCTC AGTCCAACAA CCAGAGACAT GACTTCATCC TGGCCCAGTT CATCAATGAG 
CTTCATGAGG ATGATAAAAC GTCTACAGCA CAGAACATGG ATAAAGCAGA GCAGTTTTTT 
GATCATTCCA GTGTGGAGTG TGCCATTCAG TCTTGTCCTG AATTGTTAAA GAGAGATTTT 
GAGTCCATGT TCCCTGAGGC TCCCTCAACT GGCATGATGG TGGTCACTGT GACACAGAGG 
ACGCAGAACG ACATGACTGC CTGGACTGAG CAAGTGGACC AGGAGAGAGA AGAACTGCTG 
GCTAAATTTA TTGAAGGTGC AAAGGAGATT TGCCACGCTC TCCGAAATGA AGGATTCTGG 
GCCGATTTTA TAGACCCATC ATCTGGACTT GCATACTTCG GCTCATACAC AAACAACACG 
CTCTTTGAAA CCGATGACCG GTATCGACAT TTAGGCTTTC AGATTGAGGA CCTGGGGTGT 
TGTAAAGTGA TTCGGCATGT GATGTGGGGG ACACACGCTT TTGTAGGTAC TCTTTTCACC 
TCGGCTCCAC CCAACAGCCA GATCATGAAG AAGCTACAAG GGGACCTGAG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_991157.2
CDS	118..1011
Translation	MASVLCSRARLVTYLPGLHVLVHRVVGARSFSGASGSDEPHLNTSTPDIAPRTVWPDESMGPFGPQDKRFQLPGNVGFDCHLESPVEQRTTSVHSVMPDVLTAQSNNQRHDFILAQFINELHEDDKTSTAQNMDKAEQFFDHSSVECAIQSCPELLKRDFESMFPEAPSTGMMVVTVTQRTQNDMTAWTEQVDQEREELLAKFIEGAKEICHALRNEGFWADFIDPSSGLAYFGSYTNNTLFETDDRYRHLGFQIEDLGCCKVIRHVMWGTHAFVGTLFTSAPPNSQIMKKLQGDLS

Target ORF information:

RefSeq Version	NM_205594.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio metabolism of cobalamin associated D (mmadhc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205594.2

ORF Insert Sequence:

ATGGCCAGTG TGCTCTGCAG CAGAGCTCGA CTGGTGACGT ACCTACCAGG GCTTCATGTT 
CTAGTTCATC GTGTTGTTGG AGCAAGAAGT TTCTCTGGGG CGTCAGGATC AGATGAGCCA 
CACCTGAACA CCTCAACTCC TGACATTGCA CCAAGGACTG TGTGGCCGGA TGAGAGCATG 
GGCCCATTTG GACCTCAGGA TAAACGTTTC CAGTTGCCGG GTAATGTGGG TTTTGACTGT 
CATTTGGAGA GTCCAGTGGA GCAGAGAACC ACTTCGGTCC ATAGTGTGAT GCCAGATGTG 
CTCACTGCTC AGTCCAACAA CCAGAGACAT GACTTCATCC TGGCCCAGTT CATCAATGAG 
CTTCATGAGG ATGATAAAAC GTCTACAGCA CAGAACATGG ATAAAGCAGA GCAGTTTTTT 
GATCATTCCA GTGTGGAGTG TGCCATTCAG TCTTGTCCTG AATTGTTAAA GAGAGATTTT 
GAGTCCATGT TCCCTGAGGC TCCCTCAACT GGCATGATGG TGGTCACTGT GACACAGAGG 
ACGCAGAACG ACATGACTGC CTGGACTGAG CAAGTGGACC AGGAGAGAGA AGAACTGCTG 
GCTAAATTTA TTGAAGGTGC AAAGGAGATT TGCCACGCTC TCCGAAATGA AGGATTCTGG 
GCCGATTTTA TAGACCCATC ATCTGGACTT GCATACTTCG GCTCATACAC AAACAACACG 
CTCTTTGAAA CCGATGACCG GTATCGACAT TTAGGCTTTC AGATTGAGGA CCTGGGGTGT 
TGTAAAGTGA TTCGGCATGT GATGTGGGGG ACACACGCTT TTGTAGGTAC TCTTTTCACC 
TCGGCTCCAC CCAACAGCCA GATCATGAAG AAGCTACAAG GGGACCTGAG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Many genes in fish have species-specific asymmetric rates of molecular evolution.
BMC genomics720(2006 Feb)
Steinke D,Salzburger W,Braasch I,Meyer A

Hematopoietic gene expression profile in zebrafish kidney marrow.
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)
Song HD,Sun XJ,Deng M,Zhang GW,Zhou Y,Wu XY,Sheng Y,Chen Y,Ruan Z,Jiang CL,Fan HY,Zon LI,Kanki JP,Liu TX,Look AT,Chen Z

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mmadhc cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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