BERV-K1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	BERV-K1
Entrez Gene ID	100533525
Full Name	RNA export protein-like protein of BERV-K1
Synonyms	Fematrin-1,REBK1,env
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Summary	Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene encodes a bovine endogenous retroviral envelope protein. The protein is preferentially expressed in the placenta and plays an important role in placental development. [provided by RefSeq, Sep 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001245951.2	NP_001232880.2	RNA export protein-like protein of BERV-K1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC100848463	XP_003587912.2
Bos taurus (cattle)	LOC101905346	XP_005227692.1
Bos taurus (cattle)	REBK1	NP_001232880.1

Gene Ontology
Bibliography

Related articles in PubMed

Induction of ovine trophoblast cell fusion by fematrin-1 in vitro.
Koshi K, Nakaya Y, Kizaki K, Ishiguro-Oonuma T, Miyazawa T, Spencer TE, Hashizume K
Animal science journal = Nihon chikusan Gakkaiho87(3)419-22(2016 Mar)

Expression and function of endogenous retroviruses in the placenta.
Denner J
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica124(1-2)31-43(2016 Jan-Feb)

The Roles of Syncytin-Like Proteins in Ruminant Placentation.
Nakaya Y, Miyazawa T
Viruses7(6)2928-42(2015 Jun)

Dysfunction of bovine endogenous retrovirus K2 envelope glycoprotein is related to unsuccessful intracellular trafficking.
Nakaya Y, Miyazawa T
Journal of virology88(12)6896-905(2014 Jun)

Fematrin-1 is involved in fetomaternal cell-to-cell fusion in Bovinae placenta and has contributed to diversity of ruminant placentation.
Nakaya Y, Koshi K, Nakagawa S, Hashizume K, Miyazawa T
Journal of virology87(19)10563-72(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following BERV-K1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BERV-K1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa63122	NM_001245951.2 Latest version!	Bos taurus RNA export protein-like protein of BERV-K1 (BERV-K1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BERV-K1 ( NM_001245951.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001232880.2 Bos taurus RNA export protein-like protein of BERV-K1 (BERV-K1), mRNA.

Price & Availability↑

CloneID	OBa63122
Clone ID Related Accession (Same CDS sequence)	NM_001245951.2
Accession Version	NM_001245951.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2142bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1508601600000
Organism	Bos taurus(cattle)
Product	RNA export protein-like protein of BERV-K1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DAAA02020643.1. On Aug 31, 2015 this sequence version replaced NM_001245951.1. ##RefSeq-Attributes-START## endogenous retrovirus :: PMID: 21084469 ##RefSeq-Attributes-END##

ATGTCACAGC CCCCCAGGCA TCTGGTCCCT CCACTGCCAC GACCACAAAA AAGGAAGGGA 
CCTCCTCTAC CTCCACTCCC TCCGCCAACA CGGGAAGCCC AGCTGATCTC TAGACGAATG 
ACACCAGAGA TCCTGGATGA ACAGGAAGAG GAACCACCCA CCAGACAGAT GTCACAACTC 
TGTATAAGAG ATATTGTTCT CCCTAATTCT TTACCCCACA GGAAATCACC GGGATGTCCT 
ACGCGGGCCA CTCAACAAGC CTCTATACCT ACCTGGGGAC AGATTAAGAC GCTTTGTCAC 
CAGGCACAAG GGATAGCTTC CCTGCAGGGC TCTCCAGTCT CTCCGGAGAG AGTGTTTATT 
GCTATGCTTG CCTTACTATC TTGCCAGGTA AGCGCCTCCT CTCCCGCTCC AGAAAAGTAT 
TGGGCATACT TCCCAGATCC TCCAACCTTC CAAGTAGTTA CTTGGAACAA TGCCCCTATA 
CGGGTCCACA CAAACCAGCC TCATTTATTG GGAGGACATT ATACTTTCTA TACAGAGGAG 
GAATACCCTA TTAATTTCAA TTATACCTTT AGGGGATTAA CAGATGATCT CCCTGTTTGT 
TTTAACTTCC CTTTTGATCA TACAGGAAGC TATATTACTC CTACCAAAGA AGGATGTATT 
GGAGCCTCTG AAAAAGCAAT TATAACAGAT TCTCCATCCT TAAGATATCG GTCAGTTTGG 
GTATTACTGG CTCGTATGCC TGGGATCCTT GACCCCTATA AATCCCTGCA TTTTAAATCT 
CCACCAAAAT ATCCAAATTG TCATAATGCT GCCCCTTCAG ATGCCATATG GAAAACTATA 
GATGGTCATT CAGGATATCC GATTTGGAAA TCTTGTACTT ATAATTCTAG AATTGACTAC 
AGAATACCAG GAGGAAATTA TACCATTCAG GACTGGAGCA ACCCGGATCC AGGTCAGGAT 
CCAATGATTG ATGATGCATT TAAAGGGAGA TTTGACAATT GGAAAGAATA TTCAGTTCCT 
TGGCCATTAC GCGCCACTAG ATGGCATCGT AATCAATTTG TTCCTCCTAT GCTGTCTTAT 
ACGGCTAAGG GCAGAACTTA TTGGCAACCA GAAATTTGGA AGGCCCTTAC CGCTACTGCC 
CCTATTACCT TAACCCGGCC AGAAAATATT TCTACTTATT CTATTTTAGC TTGTCTACCC 
TCGCCTTATG TTTTTCTCTT CACTAATGAT TCCAAGAGAC TTAATATACA CATGAATTAT 
TCAGGTGGAC CTAATATAGT AACTTGTGAA CAATGTATGC TCTCATCTTG TTTGGCCCCT 
CAATATAATG TTTGCTCTTT TGTGGTGTTG CAACGCCCAC CCTATCTTAT GGTGCCTGTA 
ACTATAACTA CACATTGGTA TGATAACTAT GGTCTTGCTG TAATACAACA AGTGCGGGAT 
TTAATGCGAT CACGACGGTT AGCGGGCTTA CTTTTACTGG GAATAGCAAC TTTAATAACT 
GGAATTACTT CTGTTTATAT GGCAGCAGTT TCATTGACTG AACAAGTACA CACTGCTCAA 
TATGTTGATG CTATGTCCAA AAATGTTTCT TTAGCATTGG CAACAGAGGA AGCTATATTC 
AGGAAGCTGG AGATGAGGAT AGATGCCCTA GAGGAAGCAA TATTGCATAT TGGAAATGAA 
TTGCAGGCTT TAAAAGTGAG ATTGGCACTG TCCTGTCATG CCGACTATCG GTGGATTTGT 
GTAACACCCC TGAAAGTAAA TGAGACAGAT TATGACTGGC AAAAAATTAA AAATCATATT 
TTAGGTGTCT GGAACAGCTC CGACATTAGT TTAGATTTAA GGAAACTTCA CAGTCAAATA 
ACAACCATAG AACGCTCTCA CTTAGATTTT ACTGCCTCAG GAGTAGCAAG TGACTTCTTC 
CATACAATCT CTAACTTTGT TTCAGGAAAG TACTTTCTGT CTGCTATTTT TAACTATGCT 
GCTGTGGCCG CTATAATTCT GCTTATCATA TTCATTCTTC CTTGTATTGT CAGAATTTTC 
CGACAGAGCA TTCAGAAGCT CGAGACTGAA TTGCATACGG GTTTCTTAAG AAATAAAAAT 
GGGGGAGATG CCGGGACCCA GCACGGGAGT TCCCACCCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001232880.2
CDS	1..2142
Translation	MSQPPRHLVPPLPRPQKRKGPPLPPLPPPTREAQLISRRMTPEILDEQEEEPPTRQMSQLCIRDIVLPNSLPHRKSPGCPTRATQQASIPTWGQIKTLCHQAQGIASLQGSPVSPERVFIAMLALLSCQVSASSPAPEKYWAYFPDPPTFQVVTWNNAPIRVHTNQPHLLGGHYTFYTEEEYPINFNYTFRGLTDDLPVCFNFPFDHTGSYITPTKEGCIGASEKAIITDSPSLRYRSVWVLLARMPGILDPYKSLHFKSPPKYPNCHNAAPSDAIWKTIDGHSGYPIWKSCTYNSRIDYRIPGGNYTIQDWSNPDPGQDPMIDDAFKGRFDNWKEYSVPWPLRATRWHRNQFVPPMLSYTAKGRTYWQPEIWKALTATAPITLTRPENISTYSILACLPSPYVFLFTNDSKRLNIHMNYSGGPNIVTCEQCMLSSCLAPQYNVCSFVVLQRPPYLMVPVTITTHWYDNYGLAVIQQVRDLMRSRRLAGLLLLGIATLITGITSVYMAAVSLTEQVHTAQYVDAMSKNVSLALATEEAIFRKLEMRIDALEEAILHIGNELQALKVRLALSCHADYRWICVTPLKVNETDYDWQKIKNHILGVWNSSDISLDLRKLHSQITTIERSHLDFTASGVASDFFHTISNFVSGKYFLSAIFNYAAVAAIILLIIFILPCIVRIFRQSIQKLETELHTGFLRNKNGGDAGTQHGSSHP

Target ORF information:

RefSeq Version	NM_001245951.2
Organism	Bos taurus(cattle)
Definition	Bos taurus RNA export protein-like protein of BERV-K1 (BERV-K1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001245951.2

ORF Insert Sequence:

ATGTCACAGC CCCCCAGGCA TCTGGTCCCT CCACTGCCAC GACCACAAAA AAGGAAGGGA 
CCTCCTCTAC CTCCACTCCC TCCGCCAACA CGGGAAGCCC AGCTGATCTC TAGACGAATG 
ACACCAGAGA TCCTGGATGA ACAGGAAGAG GAACCACCCA CCAGACAGAT GTCACAACTC 
TGTATAAGAG ATATTGTTCT CCCTAATTCT TTACCCCACA GGAAATCACC GGGATGTCCT 
ACGCGGGCCA CTCAACAAGC CTCTATACCT ACCTGGGGAC AGATTAAGAC GCTTTGTCAC 
CAGGCACAAG GGATAGCTTC CCTGCAGGGC TCTCCAGTCT CTCCGGAGAG AGTGTTTATT 
GCTATGCTTG CCTTACTATC TTGCCAGGTA AGCGCCTCCT CTCCCGCTCC AGAAAAGTAT 
TGGGCATACT TCCCAGATCC TCCAACCTTC CAAGTAGTTA CTTGGAACAA TGCCCCTATA 
CGGGTCCACA CAAACCAGCC TCATTTATTG GGAGGACATT ATACTTTCTA TACAGAGGAG 
GAATACCCTA TTAATTTCAA TTATACCTTT AGGGGATTAA CAGATGATCT CCCTGTTTGT 
TTTAACTTCC CTTTTGATCA TACAGGAAGC TATATTACTC CTACCAAAGA AGGATGTATT 
GGAGCCTCTG AAAAAGCAAT TATAACAGAT TCTCCATCCT TAAGATATCG GTCAGTTTGG 
GTATTACTGG CTCGTATGCC TGGGATCCTT GACCCCTATA AATCCCTGCA TTTTAAATCT 
CCACCAAAAT ATCCAAATTG TCATAATGCT GCCCCTTCAG ATGCCATATG GAAAACTATA 
GATGGTCATT CAGGATATCC GATTTGGAAA TCTTGTACTT ATAATTCTAG AATTGACTAC 
AGAATACCAG GAGGAAATTA TACCATTCAG GACTGGAGCA ACCCGGATCC AGGTCAGGAT 
CCAATGATTG ATGATGCATT TAAAGGGAGA TTTGACAATT GGAAAGAATA TTCAGTTCCT 
TGGCCATTAC GCGCCACTAG ATGGCATCGT AATCAATTTG TTCCTCCTAT GCTGTCTTAT 
ACGGCTAAGG GCAGAACTTA TTGGCAACCA GAAATTTGGA AGGCCCTTAC CGCTACTGCC 
CCTATTACCT TAACCCGGCC AGAAAATATT TCTACTTATT CTATTTTAGC TTGTCTACCC 
TCGCCTTATG TTTTTCTCTT CACTAATGAT TCCAAGAGAC TTAATATACA CATGAATTAT 
TCAGGTGGAC CTAATATAGT AACTTGTGAA CAATGTATGC TCTCATCTTG TTTGGCCCCT 
CAATATAATG TTTGCTCTTT TGTGGTGTTG CAACGCCCAC CCTATCTTAT GGTGCCTGTA 
ACTATAACTA CACATTGGTA TGATAACTAT GGTCTTGCTG TAATACAACA AGTGCGGGAT 
TTAATGCGAT CACGACGGTT AGCGGGCTTA CTTTTACTGG GAATAGCAAC TTTAATAACT 
GGAATTACTT CTGTTTATAT GGCAGCAGTT TCATTGACTG AACAAGTACA CACTGCTCAA 
TATGTTGATG CTATGTCCAA AAATGTTTCT TTAGCATTGG CAACAGAGGA AGCTATATTC 
AGGAAGCTGG AGATGAGGAT AGATGCCCTA GAGGAAGCAA TATTGCATAT TGGAAATGAA 
TTGCAGGCTT TAAAAGTGAG ATTGGCACTG TCCTGTCATG CCGACTATCG GTGGATTTGT 
GTAACACCCC TGAAAGTAAA TGAGACAGAT TATGACTGGC AAAAAATTAA AAATCATATT 
TTAGGTGTCT GGAACAGCTC CGACATTAGT TTAGATTTAA GGAAACTTCA CAGTCAAATA 
ACAACCATAG AACGCTCTCA CTTAGATTTT ACTGCCTCAG GAGTAGCAAG TGACTTCTTC 
CATACAATCT CTAACTTTGT TTCAGGAAAG TACTTTCTGT CTGCTATTTT TAACTATGCT 
GCTGTGGCCG CTATAATTCT GCTTATCATA TTCATTCTTC CTTGTATTGT CAGAATTTTC 
CGACAGAGCA TTCAGAAGCT CGAGACTGAA TTGCATACGG GTTTCTTAAG AAATAAAAAT 
GGGGGAGATG CCGGGACCCA GCACGGGAGT TCCCACCCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Induction of ovine trophoblast cell fusion by fematrin-1 in vitro.
Animal science journal = Nihon chikusan Gakkaiho87(3)419-22(2016 Mar)
Koshi K,Nakaya Y,Kizaki K,Ishiguro-Oonuma T,Miyazawa T,Spencer TE,Hashizume K

Expression and function of endogenous retroviruses in the placenta.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica124(1-2)31-43(2016 Jan-Feb)
Denner J

The Roles of Syncytin-Like Proteins in Ruminant Placentation.
Viruses7(6)2928-42(2015 Jun)
Nakaya Y,Miyazawa T

Dysfunction of bovine endogenous retrovirus K2 envelope glycoprotein is related to unsuccessful intracellular trafficking.
Journal of virology88(12)6896-905(2014 Jun)
Nakaya Y,Miyazawa T

Fematrin-1 is involved in fetomaternal cell-to-cell fusion in Bovinae placenta and has contributed to diversity of ruminant placentation.
Journal of virology87(19)10563-72(2013 Oct)
Nakaya Y,Koshi K,Nakagawa S,Hashizume K,Miyazawa T