RPGRIP1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPGRIP1
Entrez Gene ID	475400
Full Name	RPGR interacting protein 1
General protein information	Preferred Names RPGR interacting protein 1 Names X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 retinitis pigmentosa GTPase regulator interacting protein 1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001313773.1	NP_001300702.1	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
XM_022427662.1	XP_022283370.1	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rpgrip1	NP_076368.1
Homo sapiens (human)	RPGRIP1	NP_065099.3
Pan troglodytes (chimpanzee)	RPGRIP1	XP_528702.4
Macaca mulatta (Rhesus monkey)	LOC707961	XP_002808500.1
Canis lupus familiaris (dog)	RPGRIP1	XP_851597.2
Xenopus tropicalis (tropical clawed frog)	rpgrip1	XP_002939974.2
Bos taurus (cattle)	RPGRIP1	NP_851377.1
Rattus norvegicus (Norway rat)	Rpgrip1	XP_006251983.1

Gene Ontology
Bibliography

Related articles in PubMed

Variabilities in retinal function and structure in a canine model of cone-rod dystrophy associated with RPGRIP1 support multigenic etiology.
Das RG, Marinho FP, Iwabe S, Santana E, McDaid KS, Aguirre GD, Miyadera K
Scientific reports7(1)12823(2017 10)

Canine genome assembly correction facilitates identification of a MAP9 deletion as a potential age of onset modifier for RPGRIP1-associated canine retinal degeneration.
Forman OP, Hitti RJ, Boursnell M, Miyadera K, Sargan D, Mellersh C
Mammalian genome : official journal of the International Mammalian Genome Society27(5-6)237-45(2016 06)

Leber congenital amaurosis caused by mutations in RPGRIP1.
Li T
Cold Spring Harbor perspectives in medicine5(4)(2014 Nov)

Genome-wide association study in RPGRIP1(-/-) dogs identifies a modifier locus that determines the onset of retinal degeneration.
Miyadera K, Kato K, Boursnell M, Mellersh CS, Sargan DR
Mammalian genome : official journal of the International Mammalian Genome Society23(1-2)212-23(2012 Feb)

Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy.
Miyadera K, Brierley I, Aguirre-Hernández J, Mellersh CS, Sargan DR
PloS one7(12)e51598(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RPGRIP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPGRIP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe17484	NM_001313773.1 Latest version!	Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OCe293353	XM_022427662.1 Latest version!	Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPGRIP1 ( NM_001313773.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001300702.1 Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), mRNA.

Price & Availability↑

CloneID	OCe17484
Clone ID Related Accession (Same CDS sequence)	NM_001313773.1
Accession Version	NM_001313773.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1561910400000
Organism	Canis lupus familiaris(dog)
Product	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03009852.1. On Sep 1, 2015 this sequence version replaced XM_846504.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: HM021768.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGTACCAG TGTCGAAAGG TAAGAATATG AAAGCTCAAC CACCCTTGAG CAGAATGAGC 
CGGGAAGAAT TGGAGGACAG CTTGTTTCGT CTTCGTGAAG AGCACATGTT GGTGAAGGAG 
CTTTCTTGGA AGCAACAGGA TGAGATCAAA AGGGCGAGGA CCGCGCTGCT CCGGCTGACG 
GCTGCGCGCC GGGACCCCAG GGCCCCCGGG GACCCCAGGG ACCCCAGCAC CCCGGGGGCA 
GAGGCAGAGA GGCCTGCGAG GCGGCGGCAG GTGCAGCGCC CCGCGGGCCC CCCTGCACCG 
CCCGGCCGCC TGCCCCGGGC CCGCGGGGTG CACCGTGGGC TGCACTCTGT ACGGGGGCCC 
GACCGAGGCC GGAGGGAGCC CAGGGACCGG CCAAGCTACA CAGCCCCTCC TACATTCAGG 
GACCAGGCAA CAAGTGAGAA GACCGGAGGT GAAATACCCA GTGAGCCCAA TACTCTGCTA 
GTGGAAGAGC CACCCAAATC TCTGGAGAAA ATGTGGTCGA AAGGTGAAGA GTTTGAGCAG 
AGAAGCTCTT TGGAGTGTGC GCAGAAGGCC GCAGAGCTGC GAGCTTCCAT TAAGGATAAT 
ATAGAGCTGA TTCGGCTTAA GAAGCTCTTA CGTGAAAGGA ATACTTCATT AGTAGCAACA 
AAAGCACAGT TAACAGAAGT TCAAGAGGCA TATGAAACTC TGCTCCAGAA GAATCAGGGA 
ATCCTGAGTG CTGCCCATGA TGCCCTCGTT GGGCAAGTCA GTGAGCTCAG GGCAGAACTG 
AAGGAAGAGA GCAAGAAGGC TGTGAGCTTG AAGAGCCAAC TGGAAGATGT GTCCATCCTG 
CAGATAACAC TGAAGGAGTT TCAGGAGAGA GTTGAAGATT TGGAAAAAGA ACGAAAATTG 
CTGAATGACA ATTATGACAA ACTCTTAGAA AACATGCTGG CCAGCAGTAA TCAGCCTCAC 
TGGAGCAGTG AGCTCGTGGG GGAACAGCTA CGGCAGAAAG TCTCCCAGTT GCAGGACCAG 
CTGGACGCTG AGCTGGAGGA GAAGACAAAC ATCTTACTTC AACTGTCCAG AGAGAAAGCC 
CAGAGCCAGG GCCTGCGGCT CGAGGTTGCC AGCCTGCGCG GGGAGCAGGC GCGGGAAGCA 
GAGCTCGCGC CCTCGGGGGA CAGGCTGTGC CGCGGTCCCC ACAGGCCGGC GGGGGTCCAG 
GACGTGGGCC TGGCCGAGCC CCGGGATCCA GGGGACCAGG GGGACAAGAC GCTGGCGCAG 
GTGGTAAGTG AGCTGCAGGC GTCGCAGGCC GAGACAGCGC TGGAGCTGGA GAAGGCCAGG 
GACATGCTGG CCCTGCAGCG AGCCATCAAC GTGTGTTACC AGGAGGAACT GGAAGCAGTG 
ATGACGAAAG CAGACAATGA CAGTAAGGAT CACACAGAGA CACTGCAGAG GCTGACTCGC 
CTCCTGGACC TCAAGAGCCA CCGCATCCGT CAGCTGGAAG AACAGCTCAA AGATGTGGTT 
TATGGCACTC GACAGTTGTC ATTATGTCTG GAAACACAGC CAGCTCATGG AGATGAGGAT 
AACGTGGACA TTTCTCTACT GCATAAGAGT GAGAATCTTT TTGAACTGCA CATCCACCAG 
GCCTTCCTGA CATCTGCTGC CCTGGCTCAG GCTGCAGACA CTCAACCTAC CACTTTCTGC 
ACCTATTACT TCTATGACTT TGAAACCCAC TGTACCCCAC TGGCTGTGGG GCCACAGCCC 
CTCTATGATT TCACCTCCCA GTATGTAGTG GAAACGGATT CCCTTTTTTT GAACTACCTT 
CACGGGGCTT CAGCTCGGCT TGATCTACAT CAGGCTGTAG CCAGTGAGCA CCACACCCTT 
GCAGCTGGCT GGATTTGCTT TGAGAGGGTG CTGGAGACTG TGGAGAGGGT CCATGGCTCT 
ACCACACTTA CTGGAGCTGG TGGAGAAGAT TTCGGGGTGT TAGAATACTG GATGAGGCTG 
CGCTTCCCCG TAGGATCCAG CCTACAAGCA TCCAATAAGC GAAAGAAAGC TCAGGCCTAT 
CTGTCAGCCA ATGTGCCTGG AGCTTGGGAG GCCCAGGAGG ATAAGTCCAG ATTGGAGACT 
TGGAAGCATC AGAATGAGCT GCGGGTGGAA ATCATCAGAT GCCACGGCCT CCGGAGTCGA 
CGGCTGGGAA CTCAGCCCAG TCCATACGTC ATGTACCGCT TCTTCACCTT TTCTGACCAC 
GACACTGCCA TCATTCCAGC CAGTAACAAT CCCTACTTTG GAGACCAGGC TCGATTCCCA 
GTGCTTGTGA CCTCTGACCT GGATAAATAT CTGAGGCGGG AGGCCCTGTC TGTGTATGTT 
TTTGATGACG AAGACTCAGA GCCTGGCTCG TACCTTGGCC GAGTCCAAGT GCCCTTGCTT 
CCTCTTGCAC AAAATAAATC CATTAAAGGT GATTTTAACC TCACTGACCC TGCGGGGAAC 
CCCAATGGAT TTGTTGAGGC ACAACTGGAC TGGAAGTCTT TCTACCAGCC CCCAGAGAGC 
TTCCTGAAAC CAGAAGCTCA GCCTGAGGAG AACAGCACCA AGGATAGTTT AGAGAGCTCA 
TCTAAAGAGG ACCAGATGGC ATTTGCTGAG ATTCCCACCG AAGCTGGCCA GTATCAAGCT 
AAGCAAAAAC CTCCACAGGT GGGAGAAAGA AAGGAAAGGG AACATCAGGT TGCAAGCTAC 
TCAAGAAGAA AACATGGCAA AAGAACAGGC ATCCAAGGAA AGAGCAGAAT GGAATATCTT 
AGTCGTAACA TCATAACTGG AAATACATTA CAACAGGTGA ACTACACTGA ATGGAAGTTC 
TCAGGACTGA AGAGCTCCAT AGATGATGGT TTAAAATATC AGCAAAAGGA CAAGGAAATG 
ACGTCATCCC ATTCAGTAGT GATGCAGAAA GAAGCCCTAA ATCCTGTGAA TGATAAAGAA 
TCCTGTGAAC AAGCTTCTGA AGCCAGTGAA GCACAAACTA CAGATAGTGA TGACATAGTG 
ACACCAGTAT CTCTGAAATG TCCTAAGGCA GACTCGGAGA AGATGTGCAT TGAAGTGATC 
TCGCTGGCCT TCAACCCAGA GGCTGAAGTG ATGGGTGATG AGACTGTGAG GCAGGTGTAC 
GTAGAGTACA AGTTCTGCGA TGTGCCCTTG TCAGAGACAG AGACTCCGGT GTCCCTGAGG 
AAACCGAGGG CAGGAGAAGA GATCCACTTC CACTTCAGCA AAGTGATCCA CCTGGACCCG 
CTGACGCACG CGGCCCGAAG GCAGTTCCTG CGCGACGCGC TGAGCGGACG GGGCCGCGAG 
CAAGGACGTT TAAAGTTCAC GGTGGTAAGT GATCCTCTGG ACGACGAAAA GGAATGTCAA 
GAGGTGGGAT ACGCGTTTCT GGAGCTGCGC CAGGTCATGG AATCAGGAGA CCTCGTGGAA 
CAAGAGCTAG AGATCTTGAG CCCCGCGGAG CGCGCCCCCA TCGGGAGGCT GAAGGTGGGC 
GTGCGCGCGG CCGTGGCCCT GCGGGCTGTG TGCGCCGAAA TGCGGCCGCC GGGAGCCGAG 
GGAGCCGAGG GAGCCGAGGG AGCCGTCCGG AAGCAGCAGC CCCGCCGCCA GGGTACTCTC 
CCGCAGCCCA GCGACCCCGC GACCCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001300702.1
CDS	197..3826
Translation	MVPVSKGKNMKAQPPLSRMSREELEDSLFRLREEHMLVKELSWKQQDEIKRARTALLRLTAARRDPRAPGDPRDPSTPGAEAERPARRRQVQRPAGPPAPPGRLPRARGVHRGLHSVRGPDRGRREPRDRPSYTAPPTFRDQATSEKTGGEIPSEPNTLLVEEPPKSLEKMWSKGEEFEQRSSLECAQKAAELRASIKDNIELIRLKKLLRERNTSLVATKAQLTEVQEAYETLLQKNQGILSAAHDALVGQVSELRAELKEESKKAVSLKSQLEDVSILQITLKEFQERVEDLEKERKLLNDNYDKLLENMLASSNQPHWSSELVGEQLRQKVSQLQDQLDAELEEKTNILLQLSREKAQSQGLRLEVASLRGEQAREAELAPSGDRLCRGPHRPAGVQDVGLAEPRDPGDQGDKTLAQVVSELQASQAETALELEKARDMLALQRAINVCYQEELEAVMTKADNDSKDHTETLQRLTRLLDLKSHRIRQLEEQLKDVVYGTRQLSLCLETQPAHGDEDNVDISLLHKSENLFELHIHQAFLTSAALAQAADTQPTTFCTYYFYDFETHCTPLAVGPQPLYDFTSQYVVETDSLFLNYLHGASARLDLHQAVASEHHTLAAGWICFERVLETVERVHGSTTLTGAGGEDFGVLEYWMRLRFPVGSSLQASNKRKKAQAYLSANVPGAWEAQEDKSRLETWKHQNELRVEIIRCHGLRSRRLGTQPSPYVMYRFFTFSDHDTAIIPASNNPYFGDQARFPVLVTSDLDKYLRREALSVYVFDDEDSEPGSYLGRVQVPLLPLAQNKSIKGDFNLTDPAGNPNGFVEAQLDWKSFYQPPESFLKPEAQPEENSTKDSLESSSKEDQMAFAEIPTEAGQYQAKQKPPQVGERKEREHQVASYSRRKHGKRTGIQGKSRMEYLSRNIITGNTLQQVNYTEWKFSGLKSSIDDGLKYQQKDKEMTSSHSVVMQKEALNPVNDKESCEQASEASEAQTTDSDDIVTPVSLKCPKADSEKMCIEVISLAFNPEAEVMGDETVRQVYVEYKFCDVPLSETETPVSLRKPRAGEEIHFHFSKVIHLDPLTHAARRQFLRDALSGRGREQGRLKFTVVSDPLDDEKECQEVGYAFLELRQVMESGDLVEQELEILSPAERAPIGRLKVGVRAAVALRAVCAEMRPPGAEGAEGAEGAVRKQQPRRQGTLPQPSDPATP

Target ORF information:

RefSeq Version	NM_001313773.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001313773.1

ORF Insert Sequence:

ATGGTACCAG TGTCGAAAGG TAAGAATATG AAAGCTCAAC CACCCTTGAG CAGAATGAGC 
CGGGAAGAAT TGGAGGACAG CTTGTTTCGT CTTCGTGAAG AGCACATGTT GGTGAAGGAG 
CTTTCTTGGA AGCAACAGGA TGAGATCAAA AGGGCGAGGA CCGCGCTGCT CCGGCTGACG 
GCTGCGCGCC GGGACCCCAG GGCCCCCGGG GACCCCAGGG ACCCCAGCAC CCCGGGGGCA 
GAGGCAGAGA GGCCTGCGAG GCGGCGGCAG GTGCAGCGCC CCGCGGGCCC CCCTGCACCG 
CCCGGCCGCC TGCCCCGGGC CCGCGGGGTG CACCGTGGGC TGCACTCTGT ACGGGGGCCC 
GACCGAGGCC GGAGGGAGCC CAGGGACCGG CCAAGCTACA CAGCCCCTCC TACATTCAGG 
GACCAGGCAA CAAGTGAGAA GACCGGAGGT GAAATACCCA GTGAGCCCAA TACTCTGCTA 
GTGGAAGAGC CACCCAAATC TCTGGAGAAA ATGTGGTCGA AAGGTGAAGA GTTTGAGCAG 
AGAAGCTCTT TGGAGTGTGC GCAGAAGGCC GCAGAGCTGC GAGCTTCCAT TAAGGATAAT 
ATAGAGCTGA TTCGGCTTAA GAAGCTCTTA CGTGAAAGGA ATACTTCATT AGTAGCAACA 
AAAGCACAGT TAACAGAAGT TCAAGAGGCA TATGAAACTC TGCTCCAGAA GAATCAGGGA 
ATCCTGAGTG CTGCCCATGA TGCCCTCGTT GGGCAAGTCA GTGAGCTCAG GGCAGAACTG 
AAGGAAGAGA GCAAGAAGGC TGTGAGCTTG AAGAGCCAAC TGGAAGATGT GTCCATCCTG 
CAGATAACAC TGAAGGAGTT TCAGGAGAGA GTTGAAGATT TGGAAAAAGA ACGAAAATTG 
CTGAATGACA ATTATGACAA ACTCTTAGAA AACATGCTGG CCAGCAGTAA TCAGCCTCAC 
TGGAGCAGTG AGCTCGTGGG GGAACAGCTA CGGCAGAAAG TCTCCCAGTT GCAGGACCAG 
CTGGACGCTG AGCTGGAGGA GAAGACAAAC ATCTTACTTC AACTGTCCAG AGAGAAAGCC 
CAGAGCCAGG GCCTGCGGCT CGAGGTTGCC AGCCTGCGCG GGGAGCAGGC GCGGGAAGCA 
GAGCTCGCGC CCTCGGGGGA CAGGCTGTGC CGCGGTCCCC ACAGGCCGGC GGGGGTCCAG 
GACGTGGGCC TGGCCGAGCC CCGGGATCCA GGGGACCAGG GGGACAAGAC GCTGGCGCAG 
GTGGTAAGTG AGCTGCAGGC GTCGCAGGCC GAGACAGCGC TGGAGCTGGA GAAGGCCAGG 
GACATGCTGG CCCTGCAGCG AGCCATCAAC GTGTGTTACC AGGAGGAACT GGAAGCAGTG 
ATGACGAAAG CAGACAATGA CAGTAAGGAT CACACAGAGA CACTGCAGAG GCTGACTCGC 
CTCCTGGACC TCAAGAGCCA CCGCATCCGT CAGCTGGAAG AACAGCTCAA AGATGTGGTT 
TATGGCACTC GACAGTTGTC ATTATGTCTG GAAACACAGC CAGCTCATGG AGATGAGGAT 
AACGTGGACA TTTCTCTACT GCATAAGAGT GAGAATCTTT TTGAACTGCA CATCCACCAG 
GCCTTCCTGA CATCTGCTGC CCTGGCTCAG GCTGCAGACA CTCAACCTAC CACTTTCTGC 
ACCTATTACT TCTATGACTT TGAAACCCAC TGTACCCCAC TGGCTGTGGG GCCACAGCCC 
CTCTATGATT TCACCTCCCA GTATGTAGTG GAAACGGATT CCCTTTTTTT GAACTACCTT 
CACGGGGCTT CAGCTCGGCT TGATCTACAT CAGGCTGTAG CCAGTGAGCA CCACACCCTT 
GCAGCTGGCT GGATTTGCTT TGAGAGGGTG CTGGAGACTG TGGAGAGGGT CCATGGCTCT 
ACCACACTTA CTGGAGCTGG TGGAGAAGAT TTCGGGGTGT TAGAATACTG GATGAGGCTG 
CGCTTCCCCG TAGGATCCAG CCTACAAGCA TCCAATAAGC GAAAGAAAGC TCAGGCCTAT 
CTGTCAGCCA ATGTGCCTGG AGCTTGGGAG GCCCAGGAGG ATAAGTCCAG ATTGGAGACT 
TGGAAGCATC AGAATGAGCT GCGGGTGGAA ATCATCAGAT GCCACGGCCT CCGGAGTCGA 
CGGCTGGGAA CTCAGCCCAG TCCATACGTC ATGTACCGCT TCTTCACCTT TTCTGACCAC 
GACACTGCCA TCATTCCAGC CAGTAACAAT CCCTACTTTG GAGACCAGGC TCGATTCCCA 
GTGCTTGTGA CCTCTGACCT GGATAAATAT CTGAGGCGGG AGGCCCTGTC TGTGTATGTT 
TTTGATGACG AAGACTCAGA GCCTGGCTCG TACCTTGGCC GAGTCCAAGT GCCCTTGCTT 
CCTCTTGCAC AAAATAAATC CATTAAAGGT GATTTTAACC TCACTGACCC TGCGGGGAAC 
CCCAATGGAT TTGTTGAGGC ACAACTGGAC TGGAAGTCTT TCTACCAGCC CCCAGAGAGC 
TTCCTGAAAC CAGAAGCTCA GCCTGAGGAG AACAGCACCA AGGATAGTTT AGAGAGCTCA 
TCTAAAGAGG ACCAGATGGC ATTTGCTGAG ATTCCCACCG AAGCTGGCCA GTATCAAGCT 
AAGCAAAAAC CTCCACAGGT GGGAGAAAGA AAGGAAAGGG AACATCAGGT TGCAAGCTAC 
TCAAGAAGAA AACATGGCAA AAGAACAGGC ATCCAAGGAA AGAGCAGAAT GGAATATCTT 
AGTCGTAACA TCATAACTGG AAATACATTA CAACAGGTGA ACTACACTGA ATGGAAGTTC 
TCAGGACTGA AGAGCTCCAT AGATGATGGT TTAAAATATC AGCAAAAGGA CAAGGAAATG 
ACGTCATCCC ATTCAGTAGT GATGCAGAAA GAAGCCCTAA ATCCTGTGAA TGATAAAGAA 
TCCTGTGAAC AAGCTTCTGA AGCCAGTGAA GCACAAACTA CAGATAGTGA TGACATAGTG 
ACACCAGTAT CTCTGAAATG TCCTAAGGCA GACTCGGAGA AGATGTGCAT TGAAGTGATC 
TCGCTGGCCT TCAACCCAGA GGCTGAAGTG ATGGGTGATG AGACTGTGAG GCAGGTGTAC 
GTAGAGTACA AGTTCTGCGA TGTGCCCTTG TCAGAGACAG AGACTCCGGT GTCCCTGAGG 
AAACCGAGGG CAGGAGAAGA GATCCACTTC CACTTCAGCA AAGTGATCCA CCTGGACCCG 
CTGACGCACG CGGCCCGAAG GCAGTTCCTG CGCGACGCGC TGAGCGGACG GGGCCGCGAG 
CAAGGACGTT TAAAGTTCAC GGTGGTAAGT GATCCTCTGG ACGACGAAAA GGAATGTCAA 
GAGGTGGGAT ACGCGTTTCT GGAGCTGCGC CAGGTCATGG AATCAGGAGA CCTCGTGGAA 
CAAGAGCTAG AGATCTTGAG CCCCGCGGAG CGCGCCCCCA TCGGGAGGCT GAAGGTGGGC 
GTGCGCGCGG CCGTGGCCCT GCGGGCTGTG TGCGCCGAAA TGCGGCCGCC GGGAGCCGAG 
GGAGCCGAGG GAGCCGAGGG AGCCGTCCGG AAGCAGCAGC CCCGCCGCCA GGGTACTCTC 
CCGCAGCCCA GCGACCCCGC GACCCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPGRIP1 ( XM_022427662.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022283370.1 Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe293353
Clone ID Related Accession (Same CDS sequence)	XM_022427662.1
Accession Version	XM_022427662.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3135bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1504454400000
Organism	Canis lupus familiaris(dog)
Product	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006597.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTACCAG TGTCGAAAGG TAAGAATATG AAAGCTCAAC CACCCTTGAG CAGAATGAGC 
CGGGAAGAAT TGGAGGACAG CTTGTTTCGT CTTCGTGAAG AGCACATGTT GGTGAAGGAG 
CTTTCTTGGA AGCAACAGGA TGAGATCAAA AGGGCGAGGA CCGCGCTGCT CCGGCTGACG 
GCTGCGCGCC GGGACCCCAG GGCCCCCGGG GACCCCAGGG ACCCCAGCAC CCCGGGGGCA 
GAGGCAGAGA GGCCTGCGAG GCGGCGGCAG GTGCAGCGCC CCGCGGGCCC CCCTGCACCG 
CCCGGCCGCC TGCCCCGGGC CCGCGGGGTG CACCGTGGGC TGCACTCTGT ACGGGGGCCC 
GACCGAGGCC GGAGGGAGCC CAGGGACCGG CCAAGCTACA CAGCCCCTCC TACATTCAGG 
GACCAGGCAA CAAGTGAGAA GACCGGAGGT GAAATACCCA GTGAGCCCAA TACTCTGCTA 
GTGGAAGAGC CACCCAAATC TCTGGAGAAA ATGTGGTCGA AAGGTGAAGA GTTTGAGCAG 
AGAAGCTCTT TGGAGTGTGC GCAGAAGGCC GCAGAGCTGC GAGCTTCCAT TAAGGATAAT 
ATAGAGCTGA TTCGGCTTAA GAAGCTCTTA CGTGAAAGGA ATACTTCATT AGTAGCAACA 
AAAGCACAGT TAACAGAAGT TCAAGAGGCA TATGAAACTC TGCTCCAGAA GAATCAGGGA 
ATCCTGAGTG CTGCCCATGA TGCCCTCGTT GGGCAAGTCA GTGAGCTCAG GGCAGAACTG 
AAGGAAGAGA GCAAGAAGGC TGTGAGCTTG AAGAGCCAAC TGGAAGATGT GTCCATCCTG 
CAGATAACAC TGAAGGAGTT TCAGGAGAGA GTTGAAGATT TGGAAAAAGA ACGAAAATTG 
CTGAATGACA ATTATGACAA ACTCTTAGAA AACATGCTGG CCAGCAGTAA TCAGCCTCAC 
TGGAGCAGTG AGCTCGTGGG GGAACAGCTA CGGCAGAAAG TCTCCCAGTT GCAGGACCAG 
CTGGACGCTG AGCTGGAGGA GAAGACAAAC ATCTTACTTC AACTGTCCAG AGAGAAAGCC 
CAGAGCCAGG GCCTGCGGCT CGAGGTTGCC AGCCTGCGCG GGGAGCAGGC GCGGGAAGCA 
GAGCTCGCGC CCTCGGGGGA CAGGCTGTGC CGCGGTCCCC ACAGGCCGGC GGGGGTCCAG 
GACGTGGGCC TGGCCGAGCC CCGGGATCCA GGGGACCAGG GGGACAAGAC GCTGGCGCAG 
GTGGTAAGTG AGCTGCAGGC GTCGCAGGCC GAGACAGCGC TGGAGCTGGA GAAGGCCAGG 
GACATGCTGG CCCTGCAGCG AGCCATCAAC GTGTGTTACC AGGAGGAACT GGAAGCAGTG 
ATGACGAAAG CAGACAATGA CAGTAAGGAT CACACAGAGA CACTGCAGAG GCTGACTCGC 
CTCCTGGACC TCAAGAGCCA CCGCATCCGT CAGCTGGAAG AACAGCTCAA AGATGTGGTT 
TATGGCACTC GACAGTTGTC ATTATGTCTG GAAACACAGC CAGCTCATGG AGATGAGGAT 
AACGTGGACA TTTCTCTACT GCATAAGAGT GAGAATCTTT TTGAACTGCA CATCCACCAG 
GCCTTCCTGA CATCTGCTGC CCTGGCTCAG GCTGCAGACA CTCAACCTAC CACTTTCTGC 
ACCTATTACT TCTATGACTT TGAAACCCAC TGTACCCCAC TGGCTGTGGG GCCACAGCCC 
CTCTATGATT TCACCTCCCA GTATGTAGTG GAAACGGATT CCCTTTTTTT GAACTACCTT 
CACGGGGCTT CAGCTCGGCT TGATCTACAT CAGGCTGTAG CCAGTGAGCA CCACACCCTT 
GCAGCTGGCT GGATTTGCTT TGAGAGGGTG CTGGAGACTG TGGAGAGGGT CCATGGCTCT 
ACCACACTTA CTGGTGATTT TAACCTCACT GACCCTGCGG GGAACCCCAA TGGATTTGTT 
GAGGCACAAC TGGACTGGAA GTCTTTCTAC CAGCCCCCAG AGAGCTTCCT GAAACCAGAA 
GCTCAGCCTG AGGAGAACAG CACCAAGGAT AGTTTAGAGA GCTCATCTAA AGAGGACCAG 
ATGGCATTTG CTGAGATTCC CACCGAAGCT GGCCAGTATC AAGCTAAGCA AAAACCTCCA 
CAGGTGGGAG AAAGAAAGGA AAGGGAACAT CAGGTTGCAA GCTACTCAAG AAGAAAACAT 
GGCAAAAGAA CAGGCATCCA AGGAAAGAGC AGAATGGAAT ATCTTAGTCG TAACATCATA 
ACTGGAAATA CATTACAACA GGTGAACTAC ACTGAATGGA AGTTCTCAGG ACTGAAGAGC 
TCCATAGATG ATGGTTTAAA ATATCAGCAA AAGGACAAGG AAATGACGTC ATCCCATTCA 
GTAGTGATGC AGAAAGAAGC CCTAAATCCT GTGAATGATA AAGAATCCTG TGAACAAGCT 
TCTGAAGCCA GTGAAGCACA AACTACAGAT AGTGATGACA TAGTGACACC AGTATCTCTG 
AAATGTCCTA AGGCAGACTC GGAGAAGATG TGCATTGAAG TGATCTCGCT GGCCTTCAAC 
CCAGAGGCTG AAGTGATGGG TGATGAGACT GTGAGGCAGG TGTACGTAGA GTACAAGTTC 
TGCGATGTGC CCTTGTCAGA GACAGAGACT CCGGTGTCCC TGAGGAAACC GAGGGCAGGA 
GAAGAGATCC ACTTCCACTT CAGCAAAGTG ATCCACCTGG ACCCGCTGAC GCACGCGGCC 
CGAAGGCAGT TCCTGCGCGA CGCGCTGAGC GGACGGGGCC GCGAGCAAGG ACGTTTAAAG 
TTCACGGTGG TAAGTGATCC TCTGGACGAC GAAAAGGAAT GTCAAGAGGT GGGATACGCG 
TTTCTGGAGC TGCGCCAGGT CATGGAATCA GGAGACCTCG TGGAACAAGA GCTAGAGATC 
TTGAGCCCCG CGGAGCGCGC CCCCATCGGG AGGCTGAAGG TGGGCGTGCG CGCGGCCGTG 
GCCCTGCGGG CTGTGTGCGC CGAAATGCGG CCGCCGGGAG CCGAGGGAGC CGAGGGAGCC 
GAGGGAGCCG TCCGGAAGCA GCAGCCCCGC CGCCAGGGTA CTCTCCCGCA GCCCAGCGAC 
CCCGCGACCC CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022283370.1
CDS	197..3331
Translation	MVPVSKGKNMKAQPPLSRMSREELEDSLFRLREEHMLVKELSWKQQDEIKRARTALLRLTAARRDPRAPGDPRDPSTPGAEAERPARRRQVQRPAGPPAPPGRLPRARGVHRGLHSVRGPDRGRREPRDRPSYTAPPTFRDQATSEKTGGEIPSEPNTLLVEEPPKSLEKMWSKGEEFEQRSSLECAQKAAELRASIKDNIELIRLKKLLRERNTSLVATKAQLTEVQEAYETLLQKNQGILSAAHDALVGQVSELRAELKEESKKAVSLKSQLEDVSILQITLKEFQERVEDLEKERKLLNDNYDKLLENMLASSNQPHWSSELVGEQLRQKVSQLQDQLDAELEEKTNILLQLSREKAQSQGLRLEVASLRGEQAREAELAPSGDRLCRGPHRPAGVQDVGLAEPRDPGDQGDKTLAQVVSELQASQAETALELEKARDMLALQRAINVCYQEELEAVMTKADNDSKDHTETLQRLTRLLDLKSHRIRQLEEQLKDVVYGTRQLSLCLETQPAHGDEDNVDISLLHKSENLFELHIHQAFLTSAALAQAADTQPTTFCTYYFYDFETHCTPLAVGPQPLYDFTSQYVVETDSLFLNYLHGASARLDLHQAVASEHHTLAAGWICFERVLETVERVHGSTTLTGDFNLTDPAGNPNGFVEAQLDWKSFYQPPESFLKPEAQPEENSTKDSLESSSKEDQMAFAEIPTEAGQYQAKQKPPQVGERKEREHQVASYSRRKHGKRTGIQGKSRMEYLSRNIITGNTLQQVNYTEWKFSGLKSSIDDGLKYQQKDKEMTSSHSVVMQKEALNPVNDKESCEQASEASEAQTTDSDDIVTPVSLKCPKADSEKMCIEVISLAFNPEAEVMGDETVRQVYVEYKFCDVPLSETETPVSLRKPRAGEEIHFHFSKVIHLDPLTHAARRQFLRDALSGRGREQGRLKFTVVSDPLDDEKECQEVGYAFLELRQVMESGDLVEQELEILSPAERAPIGRLKVGVRAAVALRAVCAEMRPPGAEGAEGAEGAVRKQQPRRQGTLPQPSDPATP

Target ORF information:

RefSeq Version	XM_022427662.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris RPGR interacting protein 1 (RPGRIP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022427662.1

ORF Insert Sequence:

ATGGTACCAG TGTCGAAAGG TAAGAATATG AAAGCTCAAC CACCCTTGAG CAGAATGAGC 
CGGGAAGAAT TGGAGGACAG CTTGTTTCGT CTTCGTGAAG AGCACATGTT GGTGAAGGAG 
CTTTCTTGGA AGCAACAGGA TGAGATCAAA AGGGCGAGGA CCGCGCTGCT CCGGCTGACG 
GCTGCGCGCC GGGACCCCAG GGCCCCCGGG GACCCCAGGG ACCCCAGCAC CCCGGGGGCA 
GAGGCAGAGA GGCCTGCGAG GCGGCGGCAG GTGCAGCGCC CCGCGGGCCC CCCTGCACCG 
CCCGGCCGCC TGCCCCGGGC CCGCGGGGTG CACCGTGGGC TGCACTCTGT ACGGGGGCCC 
GACCGAGGCC GGAGGGAGCC CAGGGACCGG CCAAGCTACA CAGCCCCTCC TACATTCAGG 
GACCAGGCAA CAAGTGAGAA GACCGGAGGT GAAATACCCA GTGAGCCCAA TACTCTGCTA 
GTGGAAGAGC CACCCAAATC TCTGGAGAAA ATGTGGTCGA AAGGTGAAGA GTTTGAGCAG 
AGAAGCTCTT TGGAGTGTGC GCAGAAGGCC GCAGAGCTGC GAGCTTCCAT TAAGGATAAT 
ATAGAGCTGA TTCGGCTTAA GAAGCTCTTA CGTGAAAGGA ATACTTCATT AGTAGCAACA 
AAAGCACAGT TAACAGAAGT TCAAGAGGCA TATGAAACTC TGCTCCAGAA GAATCAGGGA 
ATCCTGAGTG CTGCCCATGA TGCCCTCGTT GGGCAAGTCA GTGAGCTCAG GGCAGAACTG 
AAGGAAGAGA GCAAGAAGGC TGTGAGCTTG AAGAGCCAAC TGGAAGATGT GTCCATCCTG 
CAGATAACAC TGAAGGAGTT TCAGGAGAGA GTTGAAGATT TGGAAAAAGA ACGAAAATTG 
CTGAATGACA ATTATGACAA ACTCTTAGAA AACATGCTGG CCAGCAGTAA TCAGCCTCAC 
TGGAGCAGTG AGCTCGTGGG GGAACAGCTA CGGCAGAAAG TCTCCCAGTT GCAGGACCAG 
CTGGACGCTG AGCTGGAGGA GAAGACAAAC ATCTTACTTC AACTGTCCAG AGAGAAAGCC 
CAGAGCCAGG GCCTGCGGCT CGAGGTTGCC AGCCTGCGCG GGGAGCAGGC GCGGGAAGCA 
GAGCTCGCGC CCTCGGGGGA CAGGCTGTGC CGCGGTCCCC ACAGGCCGGC GGGGGTCCAG 
GACGTGGGCC TGGCCGAGCC CCGGGATCCA GGGGACCAGG GGGACAAGAC GCTGGCGCAG 
GTGGTAAGTG AGCTGCAGGC GTCGCAGGCC GAGACAGCGC TGGAGCTGGA GAAGGCCAGG 
GACATGCTGG CCCTGCAGCG AGCCATCAAC GTGTGTTACC AGGAGGAACT GGAAGCAGTG 
ATGACGAAAG CAGACAATGA CAGTAAGGAT CACACAGAGA CACTGCAGAG GCTGACTCGC 
CTCCTGGACC TCAAGAGCCA CCGCATCCGT CAGCTGGAAG AACAGCTCAA AGATGTGGTT 
TATGGCACTC GACAGTTGTC ATTATGTCTG GAAACACAGC CAGCTCATGG AGATGAGGAT 
AACGTGGACA TTTCTCTACT GCATAAGAGT GAGAATCTTT TTGAACTGCA CATCCACCAG 
GCCTTCCTGA CATCTGCTGC CCTGGCTCAG GCTGCAGACA CTCAACCTAC CACTTTCTGC 
ACCTATTACT TCTATGACTT TGAAACCCAC TGTACCCCAC TGGCTGTGGG GCCACAGCCC 
CTCTATGATT TCACCTCCCA GTATGTAGTG GAAACGGATT CCCTTTTTTT GAACTACCTT 
CACGGGGCTT CAGCTCGGCT TGATCTACAT CAGGCTGTAG CCAGTGAGCA CCACACCCTT 
GCAGCTGGCT GGATTTGCTT TGAGAGGGTG CTGGAGACTG TGGAGAGGGT CCATGGCTCT 
ACCACACTTA CTGGTGATTT TAACCTCACT GACCCTGCGG GGAACCCCAA TGGATTTGTT 
GAGGCACAAC TGGACTGGAA GTCTTTCTAC CAGCCCCCAG AGAGCTTCCT GAAACCAGAA 
GCTCAGCCTG AGGAGAACAG CACCAAGGAT AGTTTAGAGA GCTCATCTAA AGAGGACCAG 
ATGGCATTTG CTGAGATTCC CACCGAAGCT GGCCAGTATC AAGCTAAGCA AAAACCTCCA 
CAGGTGGGAG AAAGAAAGGA AAGGGAACAT CAGGTTGCAA GCTACTCAAG AAGAAAACAT 
GGCAAAAGAA CAGGCATCCA AGGAAAGAGC AGAATGGAAT ATCTTAGTCG TAACATCATA 
ACTGGAAATA CATTACAACA GGTGAACTAC ACTGAATGGA AGTTCTCAGG ACTGAAGAGC 
TCCATAGATG ATGGTTTAAA ATATCAGCAA AAGGACAAGG AAATGACGTC ATCCCATTCA 
GTAGTGATGC AGAAAGAAGC CCTAAATCCT GTGAATGATA AAGAATCCTG TGAACAAGCT 
TCTGAAGCCA GTGAAGCACA AACTACAGAT AGTGATGACA TAGTGACACC AGTATCTCTG 
AAATGTCCTA AGGCAGACTC GGAGAAGATG TGCATTGAAG TGATCTCGCT GGCCTTCAAC 
CCAGAGGCTG AAGTGATGGG TGATGAGACT GTGAGGCAGG TGTACGTAGA GTACAAGTTC 
TGCGATGTGC CCTTGTCAGA GACAGAGACT CCGGTGTCCC TGAGGAAACC GAGGGCAGGA 
GAAGAGATCC ACTTCCACTT CAGCAAAGTG ATCCACCTGG ACCCGCTGAC GCACGCGGCC 
CGAAGGCAGT TCCTGCGCGA CGCGCTGAGC GGACGGGGCC GCGAGCAAGG ACGTTTAAAG 
TTCACGGTGG TAAGTGATCC TCTGGACGAC GAAAAGGAAT GTCAAGAGGT GGGATACGCG 
TTTCTGGAGC TGCGCCAGGT CATGGAATCA GGAGACCTCG TGGAACAAGA GCTAGAGATC 
TTGAGCCCCG CGGAGCGCGC CCCCATCGGG AGGCTGAAGG TGGGCGTGCG CGCGGCCGTG 
GCCCTGCGGG CTGTGTGCGC CGAAATGCGG CCGCCGGGAG CCGAGGGAGC CGAGGGAGCC 
GAGGGAGCCG TCCGGAAGCA GCAGCCCCGC CGCCAGGGTA CTCTCCCGCA GCCCAGCGAC 
CCCGCGACCC CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variabilities in retinal function and structure in a canine model of cone-rod dystrophy associated with RPGRIP1 support multigenic etiology.
Scientific reports7(1)12823(2017 10)
Das RG,Marinho FP,Iwabe S,Santana E,McDaid KS,Aguirre GD,Miyadera K

Canine genome assembly correction facilitates identification of a MAP9 deletion as a potential age of onset modifier for RPGRIP1-associated canine retinal degeneration.
Mammalian genome : official journal of the International Mammalian Genome Society27(5-6)237-45(2016 06)
Forman OP,Hitti RJ,Boursnell M,Miyadera K,Sargan D,Mellersh C

Leber congenital amaurosis caused by mutations in RPGRIP1.
Cold Spring Harbor perspectives in medicine5(4)(2014 Nov)
Li T

Genome-wide association study in RPGRIP1(-/-) dogs identifies a modifier locus that determines the onset of retinal degeneration.
Mammalian genome : official journal of the International Mammalian Genome Society23(1-2)212-23(2012 Feb)
Miyadera K,Kato K,Boursnell M,Mellersh CS,Sargan DR

Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy.
PloS one7(12)e51598(2012)
Miyadera K,Brierley I,Aguirre-Hernández J,Mellersh CS,Sargan DR

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RPGRIP1 cDNA ORF clone, Canis lupus familiaris(dog)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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