SLAMF1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLAMF1
Entrez Gene ID	403642
Full Name	signaling lymphocytic activation molecule family member 1
Synonyms	SLAM
General protein information	Preferred Names signaling lymphocytic activation molecule family member 1 Names signaling lymphocytic activation molecule
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003084.1	NP_001003084.1	signaling lymphocytic activation molecule precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLAMF1	NP_776609.2
Gallus gallus (chicken)	SLAMF1	XP_423077.3
Homo sapiens (human)	SLAMF1	NP_003028.1
Macaca mulatta (Rhesus monkey)	LOC719747	XP_001117605.1
Canis lupus familiaris (dog)	SLAMF1	NP_001003084.1
Pan troglodytes (chimpanzee)	SLAMF1	XP_513924.2
Mus musculus (house mouse)	Slamf1	NP_038758.2
Rattus norvegicus (Norway rat)	Slamf1	NP_001102548.1

Gene Ontology
Bibliography

Related articles in PubMed

Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM.
Khosravi M, Bringolf F, Röthlisberger S, Bieringer M, Schneider-Schaulies J, Zurbriggen A, Origgi F, Plattet P
Journal of virology90(3)1622-37(2016 02)

Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process.
Ader-Ebert N, Khosravi M, Herren M, Avila M, Alves L, Bringolf F, Örvell C, Langedijk JP, Zurbriggen A, Plemper RK, Plattet P
PLoS pathogens11(5)e1004880(2015 May)

Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus.
Melia MM, Earle JP, Abdullah H, Reaney K, Tangy F, Cosby SL
PloS one9(8)e106281(2014)

Identification of key residues in virulent canine distemper virus hemagglutinin that control CD150/SLAM-binding activity.
Zipperle L, Langedijk JP, Orvell C, Vandevelde M, Zurbriggen A, Plattet P
Journal of virology84(18)9618-24(2010 Sep)

Immunohistochemical demonstration of the putative canine distemper virus receptor CD150 in dogs with and without distemper.
Wenzlow N, Plattet P, Wittek R, Zurbriggen A, Gröne A
Veterinary pathology44(6)943-8(2007 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SLAMF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLAMF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00141	NM_001003084.1 Latest version!	Canis lupus familiaris signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLAMF1 ( NM_001003084.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003084.1 Canis lupus familiaris signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA.

Price & Availability↑

CloneID	OCe00141
Clone ID Related Accession (Same CDS sequence)	NM_001003084.1
Accession Version	NM_001003084.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550160000000
Organism	Canis lupus familiaris(dog)
Product	signaling lymphocytic activation molecule precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF325357.1. ##Evidence-Data-START## Transcript exon combination :: AF325357.1, FJ626691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013598, SAMN00013601 [ECO:0000348] ##Evidence-Data-END##

ATGGATTCCA GGGGCTTCCT CTCCCTGCGC TGCCTGCTGG TCCTCGCCCT GGCGTCCAAG 
CTGAGCTGTG GGACAGGTGA GAGCTTGATG AATTGCCCAG AAGTCCCTGG GAAGTTGGGA 
AGCAGTTTGC AGCTGTCCTT GGCATCCGAA GGGATAAGCA AGAGGATGAA CAAGAGCATC 
CACATCCTTG TCACAAGGGC GGAATCACCG GGAAACAGTA TCAAGAAGAA AATAGTGTCT 
CTGGATCTGC CAGAAGGGGG GTCTCCACGC TACCTGGAAA ATGGCTATAA ATTTCATCTG 
GAAAACCTGA CCCTGAGGAT CCTGGAAAGC AGGAGGGAAA ATGAAGGCTG GTACTTCATG 
ACCCTGGAGG AGAACTTTTC AGTTCAACAC TTTTGTCTGC AGCTGAAGCT CTATGAGCAG 
GTCTCCACTC CAGAAATTAA GGTGTTGAAC TGGACCCAGG AGAATGGGAA CTGCAGCATG 
ATGCTGGCCT GCGAAGTGGA AAAGGGGGAC AATGTGGTTT ACAGCTGGAG TGAGAAACTG 
GGGATTGACC CACTGATCCC AGCCAACAGT TCTCACCTCT TGCACCTCAG CCTCGGCCCT 
CAGCATGTCA ACAACGTCTA TGTCTGCACC GTGAGCAACC CCGTCAGCAA CCGCTCATGG 
TCCTTCAACC CATGGTCCAA GTGCAGGCCA GAGTCTTCGG TGCCAAGACA ATGGAGACTG 
TATGCTGGGC TCTTCTTAGG GGGTATCGTT GGTGTCATCT TGATTTTCGA AGTGGTATTA 
CTGCTGTTGA GAAGAAGAGG TAAAACAAAT CATTACAAGC CAACAAAGGA AGAAAAAAGC 
CTTACCATCT ATGCCCAAGT CCAGAAATCA GGTTCTACTC AGAAGAAACC TGATCCCTTG 
CCAGCTGAGG ACCCCTGCAC CACCATTTAT GTTGCTGCCA CAGAACCTGT CCCAGAACCT 
GCCCCAGAAC CTGTCCAGGA ACCACATTCT ATCACGGTCT ATGCCAGCGT GACGTTCCCA 
GAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003084.1
CDS	20..1048
Translation	MDSRGFLSLRCLLVLALASKLSCGTGESLMNCPEVPGKLGSSLQLSLASEGISKRMNKSIHILVTRAESPGNSIKKKIVSLDLPEGGSPRYLENGYKFHLENLTLRILESRRENEGWYFMTLEENFSVQHFCLQLKLYEQVSTPEIKVLNWTQENGNCSMMLACEVEKGDNVVYSWSEKLGIDPLIPANSSHLLHLSLGPQHVNNVYVCTVSNPVSNRSWSFNPWSKCRPESSVPRQWRLYAGLFLGGIVGVILIFEVVLLLLRRRGKTNHYKPTKEEKSLTIYAQVQKSGSTQKKPDPLPAEDPCTTIYVAATEPVPEPAPEPVQEPHSITVYASVTFPES

Target ORF information:

RefSeq Version	NM_001003084.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003084.1

ORF Insert Sequence:

ATGGATTCCA GGGGCTTCCT CTCCCTGCGC TGCCTGCTGG TCCTCGCCCT GGCGTCCAAG 
CTGAGCTGTG GGACAGGTGA GAGCTTGATG AATTGCCCAG AAGTCCCTGG GAAGTTGGGA 
AGCAGTTTGC AGCTGTCCTT GGCATCCGAA GGGATAAGCA AGAGGATGAA CAAGAGCATC 
CACATCCTTG TCACAAGGGC GGAATCACCG GGAAACAGTA TCAAGAAGAA AATAGTGTCT 
CTGGATCTGC CAGAAGGGGG GTCTCCACGC TACCTGGAAA ATGGCTATAA ATTTCATCTG 
GAAAACCTGA CCCTGAGGAT CCTGGAAAGC AGGAGGGAAA ATGAAGGCTG GTACTTCATG 
ACCCTGGAGG AGAACTTTTC AGTTCAACAC TTTTGTCTGC AGCTGAAGCT CTATGAGCAG 
GTCTCCACTC CAGAAATTAA GGTGTTGAAC TGGACCCAGG AGAATGGGAA CTGCAGCATG 
ATGCTGGCCT GCGAAGTGGA AAAGGGGGAC AATGTGGTTT ACAGCTGGAG TGAGAAACTG 
GGGATTGACC CACTGATCCC AGCCAACAGT TCTCACCTCT TGCACCTCAG CCTCGGCCCT 
CAGCATGTCA ACAACGTCTA TGTCTGCACC GTGAGCAACC CCGTCAGCAA CCGCTCATGG 
TCCTTCAACC CATGGTCCAA GTGCAGGCCA GAGTCTTCGG TGCCAAGACA ATGGAGACTG 
TATGCTGGGC TCTTCTTAGG GGGTATCGTT GGTGTCATCT TGATTTTCGA AGTGGTATTA 
CTGCTGTTGA GAAGAAGAGG TAAAACAAAT CATTACAAGC CAACAAAGGA AGAAAAAAGC 
CTTACCATCT ATGCCCAAGT CCAGAAATCA GGTTCTACTC AGAAGAAACC TGATCCCTTG 
CCAGCTGAGG ACCCCTGCAC CACCATTTAT GTTGCTGCCA CAGAACCTGT CCCAGAACCT 
GCCCCAGAAC CTGTCCAGGA ACCACATTCT ATCACGGTCT ATGCCAGCGT GACGTTCCCA 
GAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM.
Journal of virology90(3)1622-37(2016 02)
Khosravi M,Bringolf F,Röthlisberger S,Bieringer M,Schneider-Schaulies J,Zurbriggen A,Origgi F,Plattet P

Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process.
PLoS pathogens11(5)e1004880(2015 May)
Ader-Ebert N,Khosravi M,Herren M,Avila M,Alves L,Bringolf F,Örvell C,Langedijk JP,Zurbriggen A,Plemper RK,Plattet P

Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus.
PloS one9(8)e106281(2014)
Melia MM,Earle JP,Abdullah H,Reaney K,Tangy F,Cosby SL

Identification of key residues in virulent canine distemper virus hemagglutinin that control CD150/SLAM-binding activity.
Journal of virology84(18)9618-24(2010 Sep)
Zipperle L,Langedijk JP,Orvell C,Vandevelde M,Zurbriggen A,Plattet P

Immunohistochemical demonstration of the putative canine distemper virus receptor CD150 in dogs with and without distemper.
Veterinary pathology44(6)943-8(2007 Nov)
Wenzlow N,Plattet P,Wittek R,Zurbriggen A,Gröne A