HINTW cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	HINTW
Entrez Gene ID	395423
Full Name	histidine triad nucleotide binding protein W
Synonyms	ASW,HIM,PKCIW,WPKCI-8,Wpkci,Wpkci-7
General protein information	Preferred Names histidine triad nucleotide binding protein W Names histidine triad nucleotide binding protein W W-linked protein kinase C inhibitor avian sex-specific W-linked histidine triad missing
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
XM_025144529.1	XP_025000297.1	histidine triad nucleotide binding protein W isoform X2
XM_025144528.1	XP_025000296.1	histidine triad nucleotide binding protein W isoform X1
XM_025144530.1	XP_025000298.1	histidine triad nucleotide binding protein W isoform X3
NM_204688.2	NP_990019.1	histidine triad nucleotide binding protein W

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	HINTW	NP_990019.1
Gallus gallus (chicken)	LOC100857891	XP_004950080.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination.
Smith CA, Roeszler KN, Sinclair AH
The International journal of developmental biology53(1)59-67(2009)

Sex determination in birds: HINTs from the W sex chromosome?
Smith CA
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation1(5)279-85(2007)

Gene conversion drives the evolution of HINTW, an ampliconic gene on the female-specific avian W chromosome.
Backström N, Ceplitis H, Berlin S, Ellegren H
Molecular biology and evolution22(10)1992-9(2005 Oct)

Adaptive molecular evolution of HINTW, a female-specific gene in birds.
Ceplitis H, Ellegren H
Molecular biology and evolution21(2)249-54(2004 Feb)

A comprehensive collection of chicken cDNAs.
Boardman PE, Sanz-Ezquerro J, Overton IM, Burt DW, Bosch E, Fong WT, Tickle C, Brown WR, Wilson SA, Hubbard SJ
Current biology : CB12(22)1965-9(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HINTW gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HINTW cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa00629	NM_204688.2 Latest version!	Gallus gallus histidine triad nucleotide binding protein W (HINTW), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OGa152882	XM_025144528.1 Latest version!	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OGa152883	XM_025144529.1 Latest version!	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OGa152884	XM_025144530.1 Latest version!	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HINTW ( NM_204688.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990019.1 Gallus gallus histidine triad nucleotide binding protein W (HINTW), mRNA.

Price & Availability↑

CloneID	OGa00629
Clone ID Related Accession (Same CDS sequence)	NM_204688.2
Accession Version	NM_204688.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1526745600000
Organism	Gallus gallus(chicken)
Product	histidine triad nucleotide binding protein W
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB026677.1, AJ392963.1, BU354505.1, BU370467.1, BU142730.1, BU115472.1 and BX540786.3. On Apr 26, 2013 this sequence version replaced NM_204688.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTCGG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAGCCTGG GCTTGACCGA TGGATTCCGG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCGCGGCT CTGTATTCTG 
GGTGGCCGTC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990019.1
CDS	63..455
Translation	MAGGIVRSPAAWRGGAALLGKVARQEFSANVIREEEPLWTRSALRSMIFHRKLLRFFLAAPQKAVVGLSGAEDCGAPLLGRLMIVGEKCAASLGLTDGFRMAVRYPPSVPSDYRARLCILGGRQLGQPPG

Target ORF information:

RefSeq Version	NM_204688.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus histidine triad nucleotide binding protein W (HINTW), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204688.2

ORF Insert Sequence:

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTCGG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAGCCTGG GCTTGACCGA TGGATTCCGG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCGCGGCT CTGTATTCTG 
GGTGGCCGTC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HINTW ( XM_025144528.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_025000296.1 Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa152882
Clone ID Related Accession (Same CDS sequence)	XM_025144528.1
Accession Version	XM_025144528.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1526400000000
Organism	Gallus gallus(chicken)
Product	histidine triad nucleotide binding protein W isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006126.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGCCG CCGAGGGCGG GACCGGGCCG AGGCGAGCCG AGGCGAGCCG AGCCGTGCTG 
AGCCGTGCTG AGCCGTGCTG GGGAGGTTTG GGGCTGAGGG AGTGTTGTAG CGAGCGGGCG 
CCGTCATGGC CGGCGGGATC GTTAGGTCGC CGGCCGCCTG GCGCGGTGGC GCCGCTCTCT 
TGGGAAAAGT CGCCCGCCAG GAGTTCTCCG CCAACGTTAT CCGCGAGGAG GAGCCGTTGT 
GGACGAGGAG CCGCTCCCCA GAAGGCCGTT GTGAGGTTAT CCGGAGCAGA AGATTGTGGC 
GCACCTCTTC TTGGGCGTTT GATGATTGTT GGCGAGAAGT GTGCTGCTAA CCTGGGCCTG 
ACCAATCGAT TCCAGATGGC TGTGAGATAC CCACCCTCAG TCCCTTCAGA CTACCGCGCA 
CATCTCTGTA TTCTGGGTGG CCATCAGTTG GGCCAGCCTC CTGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_025000296.1
CDS	1238..1705
Translation	MSAAEGGTGPRRAEASRAVLSRAEPCWGGLGLRECCSERAPSWPAGSLGRRPPGAVAPLSWEKSPARSSPPTLSARRSRCGRGAAPQKAVVRLSGAEDCGAPLLGRLMIVGEKCAANLGLTNRFQMAVRYPPSVPSDYRAHLCILGGHQLGQPPG

Target ORF information:

RefSeq Version	XM_025144528.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_025144528.1

ORF Insert Sequence:

ATGAGCGCCG CCGAGGGCGG GACCGGGCCG AGGCGAGCCG AGGCGAGCCG AGCCGTGCTG 
AGCCGTGCTG AGCCGTGCTG GGGAGGTTTG GGGCTGAGGG AGTGTTGTAG CGAGCGGGCG 
CCGTCATGGC CGGCGGGATC GTTAGGTCGC CGGCCGCCTG GCGCGGTGGC GCCGCTCTCT 
TGGGAAAAGT CGCCCGCCAG GAGTTCTCCG CCAACGTTAT CCGCGAGGAG GAGCCGTTGT 
GGACGAGGAG CCGCTCCCCA GAAGGCCGTT GTGAGGTTAT CCGGAGCAGA AGATTGTGGC 
GCACCTCTTC TTGGGCGTTT GATGATTGTT GGCGAGAAGT GTGCTGCTAA CCTGGGCCTG 
ACCAATCGAT TCCAGATGGC TGTGAGATAC CCACCCTCAG TCCCTTCAGA CTACCGCGCA 
CATCTCTGTA TTCTGGGTGG CCATCAGTTG GGCCAGCCTC CTGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HINTW ( XM_025144529.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_025000297.1 Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OGa152883
Clone ID Related Accession (Same CDS sequence)	XM_025144529.1
Accession Version	XM_025144529.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1526400000000
Organism	Gallus gallus(chicken)
Product	histidine triad nucleotide binding protein W isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006126.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTCGG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAACCTGG GCTTGACCGA TGGATTCCGG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCACATCT CTGTATTCTG 
GGTGGCCATC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_025000297.1
CDS	47..439
Translation	MAGGIVRSPAAWRGGAALLGKVARQEFSANVIREEEPLWTRSALRSMIFHRKLLRFFLAAPQKAVVGLSGAEDCGAPLLGRLMIVGEKCAANLGLTDGFRMAVRYPPSVPSDYRAHLCILGGHQLGQPPG

Target ORF information:

RefSeq Version	XM_025144529.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_025144529.1

ORF Insert Sequence:

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTCGG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAACCTGG GCTTGACCGA TGGATTCCGG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCACATCT CTGTATTCTG 
GGTGGCCATC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HINTW ( XM_025144530.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_025000298.1 Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OGa152884
Clone ID Related Accession (Same CDS sequence)	XM_025144530.1
Accession Version	XM_025144530.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1526400000000
Organism	Gallus gallus(chicken)
Product	histidine triad nucleotide binding protein W isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006126.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTGAG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAACCTGG GCCTGACCAA TCGATTCCAG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCACATCT CTGTATTCTG 
GGTGGCCATC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_025000298.1
CDS	44..436
Translation	MAGGIVRSPAAWRGGAALLGKVARQEFSANVIREEEPLWTRSALRSMIFHRKLLRFFLAAPQKAVVRLSGAEDCGAPLLGRLMIVGEKCAANLGLTNRFQMAVRYPPSVPSDYRAHLCILGGHQLGQPPG

Target ORF information:

RefSeq Version	XM_025144530.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus histidine triad nucleotide binding protein W (HINTW), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_025144530.1

ORF Insert Sequence:

ATGGCCGGCG GGATCGTTAG GTCGCCGGCC GCCTGGCGCG GTGGCGCCGC TCTCTTGGGA 
AAAGTCGCCC GCCAGGAGTT CTCCGCCAAC GTTATCCGCG AGGAGGAGCC GTTGTGGACG 
AGGAGTGCCT TGCGTTCCAT GATATTTCAC CGCAAGCTCC TACGCTTTTT CCTAGCCGCT 
CCCCAGAAGG CCGTTGTGAG GTTATCCGGA GCAGAAGATT GTGGCGCACC TCTTCTTGGG 
CGTTTGATGA TTGTTGGCGA GAAGTGTGCT GCTAACCTGG GCCTGACCAA TCGATTCCAG 
ATGGCTGTGA GATACCCACC CTCAGTCCCT TCAGACTACC GCGCACATCT CTGTATTCTG 
GGTGGCCATC AGTTGGGCCA GCCTCCTGGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination.
The International journal of developmental biology53(1)59-67(2009)
Smith CA,Roeszler KN,Sinclair AH

Sex determination in birds: HINTs from the W sex chromosome?
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation1(5)279-85(2007)
Smith CA

Gene conversion drives the evolution of HINTW, an ampliconic gene on the female-specific avian W chromosome.
Molecular biology and evolution22(10)1992-9(2005 Oct)
Backström N,Ceplitis H,Berlin S,Ellegren H

Adaptive molecular evolution of HINTW, a female-specific gene in birds.
Molecular biology and evolution21(2)249-54(2004 Feb)
Ceplitis H,Ellegren H

A comprehensive collection of chicken cDNAs.
Current biology : CB12(22)1965-9(2002 Nov)
Boardman PE,Sanz-Ezquerro J,Overton IM,Burt DW,Bosch E,Fong WT,Tickle C,Brown WR,Wilson SA,Hubbard SJ

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HINTW cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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