A Novel Synthetic Self-amplifying RNA System and LNP delivery

Dr. Kangming Chen is currently the head of mRNA & Plasmid Department in GenScript Biotech. He received a B.S. in Biological Science and a M.S. in Ecology from the Lanzhou University in 2005 and 2008 respectively. Then he began his Ph.D. in South Dakota State University where he studied molecular microbiology with his dissertation advisor Dr. Ruanbao Zhou. His dissertation research focused on Regulated Intramembrane Proteolysis in cyanobacteria. He received his Ph.D. in Biology & Microbiology in the summer 2014. Afterwards, Dr. Chen began working under the supervision of Dr. Philip Hardwidge at Kansas State University, where he researches how Citrobacter rodentium type III effector NleB affecting the interferon signaling pathway. In 2016, Dr. Chen joined GenScript as a senior scientist and researched on large genome fragment synthesis. In 2022, he became the leader of mRNA & Plasmid team focusing on Plasmid preparation, IVT mRNA synthesis and LNP delivery. So far, Dr. Chen has published more than 15 peer-reviewed papers including a recent (2023) co-authored Nature paper titled A Swapped genetic code blocks viral infections and gene transfer. https://pubmed.ncbi.nlm.nih.gov/36922599/