Cdk5rap3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdk5rap3
Entrez Gene ID	80278
Full Name	CDK5 regulatory subunit associated protein 3
Synonyms	C53
General protein information	Preferred Names CDK5 regulatory subunit associated protein 3 Names CDK5 regulatory subunit-associated protein 3 CDK5 activator-binding protein C53
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	may be a substrate for phosphorylation by neuronal Cdc2-like kinase (Nclk) [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_024488.2	NP_077814.2	CDK5 regulatory subunit-associated protein 3

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009811	XP_318917.4
Pan troglodytes (chimpanzee)	CDK5RAP3	XP_003315426.1
Macaca mulatta (Rhesus monkey)	CDK5RAP3	XP_002800454.1
Bos taurus (cattle)	CDK5RAP3	NP_001068867.1
Caenorhabditis elegans (roundworm)	CELE_Y113G7B.16	NP_507910.1
Xenopus tropicalis (tropical clawed frog)	cdk5rap3	NP_001011442.1
Canis lupus familiaris (dog)	CDK5RAP3	XP_537662.4
Arabidopsis thaliana (thale cress)	AT5G06830	NP_196301.2
Homo sapiens (human)	CDK5RAP3	NP_001265126.1
Rattus norvegicus (Norway rat)	Cdk5rap3	NP_077814.1
Gallus gallus (chicken)	CDK5RAP3	NP_001026757.1
Oryza sativa (rice)	Os06g0320100	NP_001057510.1
Mus musculus (house mouse)	Cdk5rap3	NP_084524.1
Danio rerio (zebrafish)	cdk5rap3	NP_001002105.1
Drosophila melanogaster (fruit fly)	CG30291	NP_726016.1

Gene Ontology
Bibliography

Related articles in PubMed

Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope.
Wu J, Jiang H, Luo S, Zhang M, Zhang Y, Sun F, Huang S, Li H
Cell research23(5)691-704(2013 May)

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Zhang Y, Zhang M, Wu J, Lei G, Li H
PloS one7(11)e48587(2012)

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.
Lemaire K, Moura RF, Granvik M, Igoillo-Esteve M, Hohmeier HE, Hendrickx N, Newgard CB, Waelkens E, Cnop M, Schuit F
PloS one6(4)e18517(2011 Apr)

LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1).
An H, Lu X, Liu D, Yarbrough WG
PloS one6(1)e16427(2011 Jan)

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, Tagawa K, Okazawa H
The EMBO journal29(14)2446-60(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cdk5rap3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdk5rap3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa43695	NM_024488.2 Latest version!	Rattus norvegicus CDK5 regulatory subunit associated protein 3 (Cdk5rap3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdk5rap3 ( NM_024488.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077814.2 Rattus norvegicus CDK5 regulatory subunit associated protein 3 (Cdk5rap3), mRNA.

Price & Availability↑

CloneID	ORa43695
Clone ID Related Accession (Same CDS sequence)	NM_024488.2
Accession Version	NM_024488.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	CDK5 regulatory subunit-associated protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030404.1 and BC081793.1. On May 5, 2015 this sequence version replaced NM_024488.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081793.1, AF177476.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGACC ATCAGCACGT GCCCATCGAC ATCCAGACCA GCAAGCTGCT CGATTGGCTG 
GTGGACAGAA GACACTGCAA CTTAAAATGG CAAAGCCTGG TGCTGACCAT CCGGGAAAAG 
ATCAACACCG CCATCCAGGA CATGCCAGAG AGCCAAGAGA TTGCCCAGCT GCTCTCTGGT 
TCCTACATCC ACTACTTCCA CTGCCTAAGA ATAGTGGACC TTCTTAAAGG TACCGAGGCT 
TCCACCAAAA ATATTTTTGG CCGCTACTCT TCACAGCGGA TGAAGGATTG GCAGGAGATC 
ATAAGCCTGT ATGAGAAGGA CAACACCTAT TTAGTGGAAC TCTCTAGCCT CCTGGTTCGG 
AATGTCAACT ATGAGATCCC CTCTCTGAAG AAGCAGATTG CCAAGTGCCA GCAACTGCAG 
CAAGACTACA GCCGCAAGGA GGAGGAGGGC CAGGCTGGGG CTGCTGAGAT GCGAGAGCAG 
TTCTACCACT CCTGCAAACA GTACGGCATC ACGGGAGACA ATGTCCGACG AGAGCTTCTG 
GCCCTGGTGA AGGACCTGCC AAGTCAGCTG GCTGAGATAG GAGCGGGAGC TCAGTCCCTG 
GGGGAAGCCA TCGACCTGTA CCAGGCCTGT GTGGAGTTTG TATGTGACAG CCCCACAGAG 
CAGGTGCTGC CCATGCTGCG GTACGTTCAG AAGAAGGGAA ACTCCACGGT GTATGAGTGG 
AGGACAGGGA CAGAGCCCTC TGTGGTAGAG CGGCCACAAC TGGAGGACCC TCCCGAGCAG 
GTGCAAGAAG ACGAGATCGA CTGGGGCGAC TTTGGCCTGG AGGCTGTTTC TGACTCTGGA 
AACATCATCT CTGCTGAGAC CCCTGGGATA GACTGGGGTA TCTCCCTGGA GTCAGAGTCC 
AAGGATGCTG GGGCTGACAA GATAGACTGG GGTGACAATG CTGTTGCTTC GGAGATCACC 
GTGCTGGAGA CAGGAACGGA GGCTCCAGAG GGTGTTGCTA GGGGCTCAGA CGCTCTGACT 
CTCCTTGAAT ACCCTGAGAC TCGGAATCAG TTCATCGATG AGCTCATGGA GCTTGAGATC 
TTCTTGTCTC AGAGAGCAGT AGAGATGAGT GAGGAGGCTG ACATCCTGTC CGTGAGCCAG 
TTCCAGCTGG CTCCTGCCAT CCTTCAGGGC CAGACCAAGG AGAAGATGCT CAGCCTGGTG 
TCCACACTGC AGCATCTGAT TGGCCAGCTC ACCAGTCTCC GGATGCAGCA CCTGTTTATG 
ATTCTGGCCT CACCGAGGTA TGTGGACCGG GTGACAGAGC TCCTCCAGCA GAAGCTGAAG 
CAGTCCCAGC TGTTGGCTCT GAAGAAGGAC CTGATGGTGG AGAAGCAGCA GGAGGCGCTT 
CAGGAGCAGG CAGCGCTGGA GCCCAAGCTG GACCTGCTGC TGGAGAAGAC CAGAGAGCTG 
CAGAAGCTGA TTGAAGCTGA CATCTCCAAG AGATACAACG GCCGTCCTGT GAACCTGATG 
GGGACCTCTG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077814.2
CDS	98..1612
Translation	MQDHQHVPIDIQTSKLLDWLVDRRHCNLKWQSLVLTIREKINTAIQDMPESQEIAQLLSGSYIHYFHCLRIVDLLKGTEASTKNIFGRYSSQRMKDWQEIISLYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQDYSRKEEEGQAGAAEMREQFYHSCKQYGITGDNVRRELLALVKDLPSQLAEIGAGAQSLGEAIDLYQACVEFVCDSPTEQVLPMLRYVQKKGNSTVYEWRTGTEPSVVERPQLEDPPEQVQEDEIDWGDFGLEAVSDSGNIISAETPGIDWGISLESESKDAGADKIDWGDNAVASEITVLETGTEAPEGVARGSDALTLLEYPETRNQFIDELMELEIFLSQRAVEMSEEADILSVSQFQLAPAILQGQTKEKMLSLVSTLQHLIGQLTSLRMQHLFMILASPRYVDRVTELLQQKLKQSQLLALKKDLMVEKQQEALQEQAALEPKLDLLLEKTRELQKLIEADISKRYNGRPVNLMGTSV

Target ORF information:

RefSeq Version	NM_024488.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDK5 regulatory subunit associated protein 3 (Cdk5rap3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024488.2

ORF Insert Sequence:

ATGCAGGACC ATCAGCACGT GCCCATCGAC ATCCAGACCA GCAAGCTGCT CGATTGGCTG 
GTGGACAGAA GACACTGCAA CTTAAAATGG CAAAGCCTGG TGCTGACCAT CCGGGAAAAG 
ATCAACACCG CCATCCAGGA CATGCCAGAG AGCCAAGAGA TTGCCCAGCT GCTCTCTGGT 
TCCTACATCC ACTACTTCCA CTGCCTAAGA ATAGTGGACC TTCTTAAAGG TACCGAGGCT 
TCCACCAAAA ATATTTTTGG CCGCTACTCT TCACAGCGGA TGAAGGATTG GCAGGAGATC 
ATAAGCCTGT ATGAGAAGGA CAACACCTAT TTAGTGGAAC TCTCTAGCCT CCTGGTTCGG 
AATGTCAACT ATGAGATCCC CTCTCTGAAG AAGCAGATTG CCAAGTGCCA GCAACTGCAG 
CAAGACTACA GCCGCAAGGA GGAGGAGGGC CAGGCTGGGG CTGCTGAGAT GCGAGAGCAG 
TTCTACCACT CCTGCAAACA GTACGGCATC ACGGGAGACA ATGTCCGACG AGAGCTTCTG 
GCCCTGGTGA AGGACCTGCC AAGTCAGCTG GCTGAGATAG GAGCGGGAGC TCAGTCCCTG 
GGGGAAGCCA TCGACCTGTA CCAGGCCTGT GTGGAGTTTG TATGTGACAG CCCCACAGAG 
CAGGTGCTGC CCATGCTGCG GTACGTTCAG AAGAAGGGAA ACTCCACGGT GTATGAGTGG 
AGGACAGGGA CAGAGCCCTC TGTGGTAGAG CGGCCACAAC TGGAGGACCC TCCCGAGCAG 
GTGCAAGAAG ACGAGATCGA CTGGGGCGAC TTTGGCCTGG AGGCTGTTTC TGACTCTGGA 
AACATCATCT CTGCTGAGAC CCCTGGGATA GACTGGGGTA TCTCCCTGGA GTCAGAGTCC 
AAGGATGCTG GGGCTGACAA GATAGACTGG GGTGACAATG CTGTTGCTTC GGAGATCACC 
GTGCTGGAGA CAGGAACGGA GGCTCCAGAG GGTGTTGCTA GGGGCTCAGA CGCTCTGACT 
CTCCTTGAAT ACCCTGAGAC TCGGAATCAG TTCATCGATG AGCTCATGGA GCTTGAGATC 
TTCTTGTCTC AGAGAGCAGT AGAGATGAGT GAGGAGGCTG ACATCCTGTC CGTGAGCCAG 
TTCCAGCTGG CTCCTGCCAT CCTTCAGGGC CAGACCAAGG AGAAGATGCT CAGCCTGGTG 
TCCACACTGC AGCATCTGAT TGGCCAGCTC ACCAGTCTCC GGATGCAGCA CCTGTTTATG 
ATTCTGGCCT CACCGAGGTA TGTGGACCGG GTGACAGAGC TCCTCCAGCA GAAGCTGAAG 
CAGTCCCAGC TGTTGGCTCT GAAGAAGGAC CTGATGGTGG AGAAGCAGCA GGAGGCGCTT 
CAGGAGCAGG CAGCGCTGGA GCCCAAGCTG GACCTGCTGC TGGAGAAGAC CAGAGAGCTG 
CAGAAGCTGA TTGAAGCTGA CATCTCCAAG AGATACAACG GCCGTCCTGT GAACCTGATG 
GGGACCTCTG TGTGA