Usp11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Usp11
Entrez Gene ID	408217
Full Name	ubiquitin specific peptidase 11
Synonyms	Uhx1
General protein information	Preferred Names ubiquitin specific peptidase 11 Names ubiquitin carboxyl-terminal hydrolase 11 deubiquitinating enzyme 11 ubiquitin specific protease 11 ubiquitin thioesterase 11 ubiquitin-specific-processing protease 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq11
Summary	deubiquitinating enzyme; cleaves ubiquitin from ubiquitin-conjugated protein substrates; important for processes such as cell cycle progression and transcriptional activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008861.2	NP_001008861.2	ubiquitin carboxyl-terminal hydrolase 11

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	USP11	XP_001093504.1
Canis lupus familiaris (dog)	USP11	NP_001183969.1
Mus musculus (house mouse)	Usp11	NP_663603.3
Bos taurus (cattle)	USP11	NP_001073777.1
Rattus norvegicus (Norway rat)	Usp11	NP_001008861.2
Danio rerio (zebrafish)	usp11	XP_002663119.3
Homo sapiens (human)	USP11	NP_004642.2

Gene Ontology
Bibliography

Related articles in PubMed

USP11, Deubiquitinating Enzyme, Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage.
Xu Z, Li X, Chen J, Zhao J, Wang J, Ji Y, Shen Y, Han L, Shi J, Zhang D
Journal of molecular neuroscience : MN58(1)16-27(2016 Jan)

BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage.
Schoenfeld AR, Apgar S, Dolios G, Wang R, Aaronson SA
Molecular and cellular biology24(17)7444-55(2004 Sep)

A genomic analysis of rat proteases and protease inhibitors.
Puente XS, López-Otín C
Genome research14(4)609-22(2004 Apr)

Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM.
Ideguchi H, Ueda A, Tanaka M, Yang J, Tsuji T, Ohno S, Hagiwara E, Aoki A, Ishigatsubo Y
The Biochemical journal367(Pt 1)87-95(2002 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Usp11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09527	NM_001008861.2 Latest version!	Rattus norvegicus ubiquitin specific peptidase 11 (Usp11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Usp11 ( NM_001008861.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008861.2 Rattus norvegicus ubiquitin specific peptidase 11 (Usp11), mRNA.

Price & Availability↑

CloneID	ORa09527
Clone ID Related Accession (Same CDS sequence)	NM_001008861.2
Accession Version	NM_001008861.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2766bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550246400000
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin carboxyl-terminal hydrolase 11
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090333.1. On Sep 28, 2005 this sequence version replaced NM_001008861.1. ##Evidence-Data-START## Transcript exon combination :: BC090333.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGG TCGCAGCGGA CCCAGCTGCA GCTGCCGTCC CGGCCTCTGC TGAGGACAGA 
GAGACACAGC CCGAGGCAAT GCCAGACCTG GATCAACAGT GGCGCCAAAT CGGGAATGGG 
CGAGAGCGTC CACTGCGAGC TGGCGAAAGC TGGTTCCTTG TGGAGAAACA CTGGTATAAA 
CAGTGGGAGG CGTATGTGAA GGGAGGGGAT CAAGATGCTA GCACCTTTCC TGGCAGTATC 
AACAATTCGG GGCTCTTTGA AGATCAGATA AGCTGGCACC TCAGGGAGAG ACTGGTAGAA 
GGAGATGATT ATGTGCTGCT CCCAGCGCCT GCTTGGAACT ACCTGGTCAG CTGGTATGGC 
TTAAAGGATG ACCAGCCACC TATTGAGCGC AAGGTCATAG AACTTCCTGG CATTCGAAAG 
GTGGAAGTGT ACCCAATAGA GCTGCTGCTC GTTCAGCACA GTGATATGGA AACAGCTCTC 
ACCATTCAGT TTAGCTATTC TGATTCTGTC GACCTAGTCT TGCAAACAGC CCGGGAGCAG 
TTTCTGGTAG AGCCTCAGGA AGACACGCGC CTCTGGACCA AGAACTCAGA GGGCTCTTTG 
GATCGATTAT GTAACACGCA GATCACACTG CTTGATGCCT GCCTTGAGAC TGGGCAGTTG 
GTCATCATGG AGACCCGAAA CAAAGATGGC ACTTGGCCCA GCGCTCAGCT GTGTGGCATG 
AACAACATGC CGGACGAGGA TGAGGACTTC CAGGGCCAAC CAGGCATCTG TGGCCTTACC 
AATCTGGGCA ACACGTGCTT CATGAACTCG GCCCTACAGT GCCTCAGCAA TGTGCCACAG 
CTTACGGAGT ACTTTCTCAA CAACCGCTAC CTGGAGGAGC TCAACTTCCG GAACCCTCTG 
GGCATGAAGG GTGAGCTTGC TGAGGCCTAT GCAGATCTGG TAAAGCAGAC TTGGTCTGGC 
TACCACCGCT CCATTGTGCC GAATGTTTTC AAGAACAAGG TTGGCCATTT CGCATCCCAG 
TTTCTGGGCT ACCAGCAGCA TGACTCACAG GAACTACTGT CATTCCTCCT GGATGGACTA 
CATGAGGACC TCAATCGAGT CAAAAAGAAA GAATATGTTG AGCTATGCAA TGGTGCTGGG 
CGGCCTGATC TGGAAGTGGC TCAGGAAGCC TGGCAGAACC ACAAACGACG AAATGATTCT 
GTGATTGTGG ACACTTTCCA TGGCCTCTTC AAGTCTACAC TGGTGTGCCC TGATTGTGGC 
AATGTTTCTG TGACCTTTGA CCCCTTCTGC TACCTCAGTG TCCCACTGCC TGTCTGCTCC 
AGGAGGGTCT TGGAGGTCTT CTTTGTCCCC ATGGATCCCC GCCGCAAGCC AGAACAGCAC 
CGGGTTGTAG TCCCTAAGAA GGGCAATATC TCAGATCTGT GTGTGGCTCT GTCCACACAT 
ACAAGTGTTG CACCAGATAA GATGATAGTA GCTGATGTCT TCAGTCACCG ATTCTATAAG 
CTCTACCAGC TGGAGGATCC TCTGAGTGGC ATCTTGGATC GTGATGATAT CTTTGTATAT 
GAGGTGACTG GACGGATTGA GCCTGTTGAG GGTTCAAGAG ATGATATTGT GGTTCCTGTT 
TACCTGCGGG AGCGCACCCC GTCCAGAGAC TACAACAACT CCTACTACGG TCTGATACTT 
TTTGGGCACC CTCTCCTGGT GTCAGTGCCC CGGGACCGGT TCTCCTGGGA GGGCCTATAT 
AACATCTTGA TGTACCGGCT TTCACGATAT GTGACCAAAC CCACCTCAGA TGACGATGAT 
GGGGATGAGA AAGGTGATGA GAATGAGGAT GAGGATGTCG AAGATGACAG CAGCAGTGAA 
GAAGAAAAGG AGGAAATGTC TGGACCTACC GATAATGATG GTACCCAAGA ATCAGAGCAG 
GAGCAGGCTG GGACCAGCTC TGGGGTCACC GGAAGATGCC CATCCCTCTT AGACAACAGC 
CTCCACACAT CGCAGTGGCC CCCAAGGCGA CGACGAAAGC AATTGTTTAC TCTGCAGACA 
GTGAACTCCA ATGGAACCAG TGACCGGACC ACCTCCCCTG AAGAAGCCCA AACTCAGCCG 
TACATTGCCA TGGATTGGGA ACCAGAGATG AAGAGGCGCT ATTATGATGA AGTAGAGGCT 
GAGGGCTATG TGAAGCATGA CTGCGTGGGA TACATGCTGA AGAAGAATCC AGTGCAGCTG 
AAGGAGTGCA TCAAACTCTT CACCACTGTG GAAACCCTTG AGAAGGAGAA CCCTTGGTAT 
TGCTCCTCCT GCAAGCAGCA CCAGCTAGCC ACTAAGAAAC TGGACCTCTG GATGCTACCT 
GAAGTTCTCA TTATCCATCT GAAGCGTTTT TCATTTTCCA AATTTTCCCG GGAGAAGCTG 
GACACCCTGG TGCAGTTTCC TATCCGGGAT CTGGATTTCT CTGAGTTTGT CATCAAACCA 
AAGAATGAGT CTGCTCCAGA CCTGTACAAA TATGATCTCA TCGCAGTTTC CAACCATTAT 
GGTGGCATGC GTGATGGACA CTATACAACA TTTGCCTGCA ACAAGGACAG TGGCCAGTGG 
CACTACTTTG ATGACAACAG TGTCTCACCT GTGAATGAGA ATCAGATTGA GTCCAAGGCA 
GCCTATGTCT TGTTCTATCA ACGCCAAGAT GTGGGTCGAC GCCAGTCCCA GACTGCTTCA 
TCTGAGACCC CCACCTCTCC TGCTTCGAGT TCTACACCCA ACTCTGACAT CATGGATGTC 
AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008861.2
CDS	10..2775
Translation	MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN

Target ORF information:

RefSeq Version	NM_001008861.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin specific peptidase 11 (Usp11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008861.2

ORF Insert Sequence:

ATGGCGGCGG TCGCAGCGGA CCCAGCTGCA GCTGCCGTCC CGGCCTCTGC TGAGGACAGA 
GAGACACAGC CCGAGGCAAT GCCAGACCTG GATCAACAGT GGCGCCAAAT CGGGAATGGG 
CGAGAGCGTC CACTGCGAGC TGGCGAAAGC TGGTTCCTTG TGGAGAAACA CTGGTATAAA 
CAGTGGGAGG CGTATGTGAA GGGAGGGGAT CAAGATGCTA GCACCTTTCC TGGCAGTATC 
AACAATTCGG GGCTCTTTGA AGATCAGATA AGCTGGCACC TCAGGGAGAG ACTGGTAGAA 
GGAGATGATT ATGTGCTGCT CCCAGCGCCT GCTTGGAACT ACCTGGTCAG CTGGTATGGC 
TTAAAGGATG ACCAGCCACC TATTGAGCGC AAGGTCATAG AACTTCCTGG CATTCGAAAG 
GTGGAAGTGT ACCCAATAGA GCTGCTGCTC GTTCAGCACA GTGATATGGA AACAGCTCTC 
ACCATTCAGT TTAGCTATTC TGATTCTGTC GACCTAGTCT TGCAAACAGC CCGGGAGCAG 
TTTCTGGTAG AGCCTCAGGA AGACACGCGC CTCTGGACCA AGAACTCAGA GGGCTCTTTG 
GATCGATTAT GTAACACGCA GATCACACTG CTTGATGCCT GCCTTGAGAC TGGGCAGTTG 
GTCATCATGG AGACCCGAAA CAAAGATGGC ACTTGGCCCA GCGCTCAGCT GTGTGGCATG 
AACAACATGC CGGACGAGGA TGAGGACTTC CAGGGCCAAC CAGGCATCTG TGGCCTTACC 
AATCTGGGCA ACACGTGCTT CATGAACTCG GCCCTACAGT GCCTCAGCAA TGTGCCACAG 
CTTACGGAGT ACTTTCTCAA CAACCGCTAC CTGGAGGAGC TCAACTTCCG GAACCCTCTG 
GGCATGAAGG GTGAGCTTGC TGAGGCCTAT GCAGATCTGG TAAAGCAGAC TTGGTCTGGC 
TACCACCGCT CCATTGTGCC GAATGTTTTC AAGAACAAGG TTGGCCATTT CGCATCCCAG 
TTTCTGGGCT ACCAGCAGCA TGACTCACAG GAACTACTGT CATTCCTCCT GGATGGACTA 
CATGAGGACC TCAATCGAGT CAAAAAGAAA GAATATGTTG AGCTATGCAA TGGTGCTGGG 
CGGCCTGATC TGGAAGTGGC TCAGGAAGCC TGGCAGAACC ACAAACGACG AAATGATTCT 
GTGATTGTGG ACACTTTCCA TGGCCTCTTC AAGTCTACAC TGGTGTGCCC TGATTGTGGC 
AATGTTTCTG TGACCTTTGA CCCCTTCTGC TACCTCAGTG TCCCACTGCC TGTCTGCTCC 
AGGAGGGTCT TGGAGGTCTT CTTTGTCCCC ATGGATCCCC GCCGCAAGCC AGAACAGCAC 
CGGGTTGTAG TCCCTAAGAA GGGCAATATC TCAGATCTGT GTGTGGCTCT GTCCACACAT 
ACAAGTGTTG CACCAGATAA GATGATAGTA GCTGATGTCT TCAGTCACCG ATTCTATAAG 
CTCTACCAGC TGGAGGATCC TCTGAGTGGC ATCTTGGATC GTGATGATAT CTTTGTATAT 
GAGGTGACTG GACGGATTGA GCCTGTTGAG GGTTCAAGAG ATGATATTGT GGTTCCTGTT 
TACCTGCGGG AGCGCACCCC GTCCAGAGAC TACAACAACT CCTACTACGG TCTGATACTT 
TTTGGGCACC CTCTCCTGGT GTCAGTGCCC CGGGACCGGT TCTCCTGGGA GGGCCTATAT 
AACATCTTGA TGTACCGGCT TTCACGATAT GTGACCAAAC CCACCTCAGA TGACGATGAT 
GGGGATGAGA AAGGTGATGA GAATGAGGAT GAGGATGTCG AAGATGACAG CAGCAGTGAA 
GAAGAAAAGG AGGAAATGTC TGGACCTACC GATAATGATG GTACCCAAGA ATCAGAGCAG 
GAGCAGGCTG GGACCAGCTC TGGGGTCACC GGAAGATGCC CATCCCTCTT AGACAACAGC 
CTCCACACAT CGCAGTGGCC CCCAAGGCGA CGACGAAAGC AATTGTTTAC TCTGCAGACA 
GTGAACTCCA ATGGAACCAG TGACCGGACC ACCTCCCCTG AAGAAGCCCA AACTCAGCCG 
TACATTGCCA TGGATTGGGA ACCAGAGATG AAGAGGCGCT ATTATGATGA AGTAGAGGCT 
GAGGGCTATG TGAAGCATGA CTGCGTGGGA TACATGCTGA AGAAGAATCC AGTGCAGCTG 
AAGGAGTGCA TCAAACTCTT CACCACTGTG GAAACCCTTG AGAAGGAGAA CCCTTGGTAT 
TGCTCCTCCT GCAAGCAGCA CCAGCTAGCC ACTAAGAAAC TGGACCTCTG GATGCTACCT 
GAAGTTCTCA TTATCCATCT GAAGCGTTTT TCATTTTCCA AATTTTCCCG GGAGAAGCTG 
GACACCCTGG TGCAGTTTCC TATCCGGGAT CTGGATTTCT CTGAGTTTGT CATCAAACCA 
AAGAATGAGT CTGCTCCAGA CCTGTACAAA TATGATCTCA TCGCAGTTTC CAACCATTAT 
GGTGGCATGC GTGATGGACA CTATACAACA TTTGCCTGCA ACAAGGACAG TGGCCAGTGG 
CACTACTTTG ATGACAACAG TGTCTCACCT GTGAATGAGA ATCAGATTGA GTCCAAGGCA 
GCCTATGTCT TGTTCTATCA ACGCCAAGAT GTGGGTCGAC GCCAGTCCCA GACTGCTTCA 
TCTGAGACCC CCACCTCTCC TGCTTCGAGT TCTACACCCA ACTCTGACAT CATGGATGTC 
AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

USP11, Deubiquitinating Enzyme, Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage.
Journal of molecular neuroscience : MN58(1)16-27(2016 Jan)
Xu Z,Li X,Chen J,Zhao J,Wang J,Ji Y,Shen Y,Han L,Shi J,Zhang D

BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage.
Molecular and cellular biology24(17)7444-55(2004 Sep)
Schoenfeld AR,Apgar S,Dolios G,Wang R,Aaronson SA

A genomic analysis of rat proteases and protease inhibitors.
Genome research14(4)609-22(2004 Apr)
Puente XS,López-Otín C

Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM.
The Biochemical journal367(Pt 1)87-95(2002 Oct)
Ideguchi H,Ueda A,Tanaka M,Yang J,Tsuji T,Ohno S,Hagiwara E,Aoki A,Ishigatsubo Y

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Usp11 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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