Cnksr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cnksr1
Entrez Gene ID	298545
Full Name	connector enhancer of kinase suppressor of Ras 1
General protein information	Preferred Names connector enhancer of kinase suppressor of Ras 1 Names connector enhancer of kinase suppressor of ras 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039011.1	NP_001034100.1	connector enhancer of kinase suppressor of ras 1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	CNKSR1	XP_002808325.1
Xenopus tropicalis (tropical clawed frog)	cnksr1	NP_001116896.1
Rattus norvegicus (Norway rat)	Cnksr1	NP_001034100.1
Gallus gallus (chicken)	CNKSR1	XP_004947732.1
Homo sapiens (human)	CNKSR1	NP_006305.2
Danio rerio (zebrafish)	cnksr1	NP_991222.1
Canis lupus familiaris (dog)	CNKSR1	XP_003638970.2
Pan troglodytes (chimpanzee)	CNKSR1	XP_524626.2
Bos taurus (cattle)	LOC617552	NP_001180094.1
Mus musculus (house mouse)	Cnksr1	NP_001074516.1

Gene Ontology
Bibliography

Related articles in PubMed

An ATIPical family of angiotensin II AT2 receptor-interacting proteins.
Rodrigues-Ferreira S, Nahmias C
Trends in endocrinology and metabolism: TEM21(11)684-90(2010 Nov)

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B
The Journal of biological chemistry279(28)29247-54(2004 Jul)

Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways.
Jaffe AB, Aspenström P, Hall A
Molecular and cellular biology24(4)1736-46(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cnksr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cnksr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08362	NM_001039011.1 Latest version!	Rattus norvegicus connector enhancer of kinase suppressor of Ras 1 (Cnksr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cnksr1 ( NM_001039011.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001034100.1 Rattus norvegicus connector enhancer of kinase suppressor of Ras 1 (Cnksr1), mRNA.

Price & Availability↑

CloneID	ORa08362
Clone ID Related Accession (Same CDS sequence)	NM_001039011.1
Accession Version	NM_001039011.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2115bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Rattus norvegicus(Norway rat)
Product	connector enhancer of kinase suppressor of ras 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099788.1. On Jan 12, 2006 this sequence version replaced XM_216548.3. ##Evidence-Data-START## Transcript exon combination :: BC099788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689600 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCCG TGGAGACCTG GACCCCCGGG AAGGTGGCAG CTTGGCTGAG AGGCCTTGAT 
GACGTCCTAC AGGACTATCC CTTCGAGGAC TGGGAGCTGC CTGGAAAGTA CCTGCTGCAG 
CTCTGTCCCC AAAACCTCGA GGCTCTGACC GTGTGGCCTC TGGGCCACCA GGAGCTCATT 
CTACATGGAG TGGAACAGCT CCGGGCCCTG GGCTCTAAGT TACAGACCGA GAACCTCAAG 
AGCCTAGCCC AGGGGCTGCT GGACAGGACC CAGGCCTTCC AAAGCTTGGT CCAAGGCCGT 
CTGAGAGACT GTGCTGAGAC ACCCGCCGAT GTCCTCAATG CTGCTGTAGA GCTGGTACGG 
GAGGCTCATG CCCTGCTCTC TTGGCTCAAC AGGTACCTCT TCACTCACTT AAATGACTTC 
TCCGCCTGCC AAGAGATTGG TGTGCTGTGC GGAGAGCTGG GCCAAGTCTT GCAGGAGGAT 
TGCCTAGAGG CTGAGAAAGA AAGCAACACC CTGAGGATTT GCGGCCGTGT GGCTGGGATC 
TGTCACAACA TCCTGGGCTG CAGCCCGGAG GAGCTGCTGG AACAGAGGGC CGTGTTGGAG 
CTGGTGCAGC TGGACGACCC TTCCGGCCTA GAAATTCACA CCACCAGCAA CTGCCTACAC 
TTTGTGTCTC GAGTAGGCGT CCAGGCTGCC ACCGGCTCCC AGATCCTGCC CGGAGATGAG 
ATCATCCAAA TCAATGAGCA GGTGGTGGTC GGCTGGCCCC ATAAAAACAT GCTGAGGGAG 
CTGCTGAGGG AGCCAGCAAG GGTCAGCCTT GTACTAAAGA AGATTCCCGT GCCAGAGACC 
CCCTCAAAGA CGCCCCCGGA CTCCCCTCAG CGGCTAAGCC AATCGCTGCC CCTGAACCCA 
CCGTCTCCCA GGGTTCCACG CGAAGGTCTT TTTGACTTCA AGCTGTTTAC AGATGGAAAC 
CCCAGCCCCA GCCCTGCGTG GACAGACTCT ACCTCCCTTG ACGCTCAGCC CACGCCCACT 
CCCCCTGGGC CACCAGGCAC TCTTCCAGAA GAAACAGCAG AACCTCTGGA GGCTTCGGGA 
CACCTTGACA AGAGTCCCAC CGTTGGTCGG AAGAATTCAA AAGGTATAGC TACAAGGCTG 
AGCCGCCGGC GGGTGTCCTG CCGAGAGCTG GGTCTGCCGG ACTGTGATGG ATGGCTTCTA 
CTGCGGAAGG TACCCGGTGG TTTTATGGGC GCTCGCTGGC GTCGCTGCTG GTTCGTGCTC 
AAGGGACACA CCCTATACTG GTACCGCCAA CCGCAGGATG AAAAGGCGGA AGGACTTATC 
AACATCTCCA ATTACAGCCT GGAGTGCGGG CATGACCAGA AGAAAAAATA TGTGTTCCAG 
CTGACCCACG ATGTGTACAA GCCCTTCATC TTTGCCTCGG AGACCCTGTC TGATCTGAGC 
ATGTGGGTGC GGCATCTTGT CACCTGCATT TCCAAGTATC AGACTCTAGG TCGGGCCCCC 
TCCGCCAGAG AGGAAGACTG CTACAGTGAG ACCGAAGCAG AAGACCCTGA TGAAGAGGCA 
GGGTCCCGCT CAGCTTCTCC TGGTCCAGCT CAAGCTTGGA ATGACACATC GCCCTCGGCT 
TCACCCCTGC AGAGTCCTAG GACCTCCTTT GGCTCTTCAT TAGATAGCAG TGACAGAGCC 
CTGGAAGGAA TGGTACAGGG GCTGAGGCAG GGAGGCGTGT CCCTCCTGGG CCAGCCACAG 
CCCTTGACCC ATGAACAGTG GCGGAGTTCT TTCATGCGGC GAAACCGTGA CCCTCATCTC 
AATGAGCATG TGCACCGTGT CCGGGCACTA CAGAGCACAC TCAAGGCAAA GCTACAGGAA 
CTGCAGGTCC TGGAGGAAGT CCTGGGTGAT CCTGAACTCA CAGGAGCAAA ATTTCGCCAG 
TGGAAGGAAC AGAACCACGA GCTGTACTCA GAAGGCCTGA GGACCTGGGG AGGGATGTGG 
GCCCAGACCA GCTCCCCAGA CCCAAACACT GACTCCAGGG GTCAATCCCC ACAGCCTCTA 
CCCTCTGACC CTGAAGAGCC CTCCCAGCTT TTTCCCTCGA CCCCAGAGAA CAGCCTCCAA 
CCTCCTGACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034100.1
CDS	28..2142
Translation	MEPVETWTPGKVAAWLRGLDDVLQDYPFEDWELPGKYLLQLCPQNLEALTVWPLGHQELILHGVEQLRALGSKLQTENLKSLAQGLLDRTQAFQSLVQGRLRDCAETPADVLNAAVELVREAHALLSWLNRYLFTHLNDFSACQEIGVLCGELGQVLQEDCLEAEKESNTLRICGRVAGICHNILGCSPEELLEQRAVLELVQLDDPSGLEIHTTSNCLHFVSRVGVQAATGSQILPGDEIIQINEQVVVGWPHKNMLRELLREPARVSLVLKKIPVPETPSKTPPDSPQRLSQSLPLNPPSPRVPREGLFDFKLFTDGNPSPSPAWTDSTSLDAQPTPTPPGPPGTLPEETAEPLEASGHLDKSPTVGRKNSKGIATRLSRRRVSCRELGLPDCDGWLLLRKVPGGFMGARWRRCWFVLKGHTLYWYRQPQDEKAEGLINISNYSLECGHDQKKKYVFQLTHDVYKPFIFASETLSDLSMWVRHLVTCISKYQTLGRAPSAREEDCYSETEAEDPDEEAGSRSASPGPAQAWNDTSPSASPLQSPRTSFGSSLDSSDRALEGMVQGLRQGGVSLLGQPQPLTHEQWRSSFMRRNRDPHLNEHVHRVRALQSTLKAKLQELQVLEEVLGDPELTGAKFRQWKEQNHELYSEGLRTWGGMWAQTSSPDPNTDSRGQSPQPLPSDPEEPSQLFPSTPENSLQPPDL

Target ORF information:

RefSeq Version	NM_001039011.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus connector enhancer of kinase suppressor of Ras 1 (Cnksr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039011.1

ORF Insert Sequence:

ATGGAGCCCG TGGAGACCTG GACCCCCGGG AAGGTGGCAG CTTGGCTGAG AGGCCTTGAT 
GACGTCCTAC AGGACTATCC CTTCGAGGAC TGGGAGCTGC CTGGAAAGTA CCTGCTGCAG 
CTCTGTCCCC AAAACCTCGA GGCTCTGACC GTGTGGCCTC TGGGCCACCA GGAGCTCATT 
CTACATGGAG TGGAACAGCT CCGGGCCCTG GGCTCTAAGT TACAGACCGA GAACCTCAAG 
AGCCTAGCCC AGGGGCTGCT GGACAGGACC CAGGCCTTCC AAAGCTTGGT CCAAGGCCGT 
CTGAGAGACT GTGCTGAGAC ACCCGCCGAT GTCCTCAATG CTGCTGTAGA GCTGGTACGG 
GAGGCTCATG CCCTGCTCTC TTGGCTCAAC AGGTACCTCT TCACTCACTT AAATGACTTC 
TCCGCCTGCC AAGAGATTGG TGTGCTGTGC GGAGAGCTGG GCCAAGTCTT GCAGGAGGAT 
TGCCTAGAGG CTGAGAAAGA AAGCAACACC CTGAGGATTT GCGGCCGTGT GGCTGGGATC 
TGTCACAACA TCCTGGGCTG CAGCCCGGAG GAGCTGCTGG AACAGAGGGC CGTGTTGGAG 
CTGGTGCAGC TGGACGACCC TTCCGGCCTA GAAATTCACA CCACCAGCAA CTGCCTACAC 
TTTGTGTCTC GAGTAGGCGT CCAGGCTGCC ACCGGCTCCC AGATCCTGCC CGGAGATGAG 
ATCATCCAAA TCAATGAGCA GGTGGTGGTC GGCTGGCCCC ATAAAAACAT GCTGAGGGAG 
CTGCTGAGGG AGCCAGCAAG GGTCAGCCTT GTACTAAAGA AGATTCCCGT GCCAGAGACC 
CCCTCAAAGA CGCCCCCGGA CTCCCCTCAG CGGCTAAGCC AATCGCTGCC CCTGAACCCA 
CCGTCTCCCA GGGTTCCACG CGAAGGTCTT TTTGACTTCA AGCTGTTTAC AGATGGAAAC 
CCCAGCCCCA GCCCTGCGTG GACAGACTCT ACCTCCCTTG ACGCTCAGCC CACGCCCACT 
CCCCCTGGGC CACCAGGCAC TCTTCCAGAA GAAACAGCAG AACCTCTGGA GGCTTCGGGA 
CACCTTGACA AGAGTCCCAC CGTTGGTCGG AAGAATTCAA AAGGTATAGC TACAAGGCTG 
AGCCGCCGGC GGGTGTCCTG CCGAGAGCTG GGTCTGCCGG ACTGTGATGG ATGGCTTCTA 
CTGCGGAAGG TACCCGGTGG TTTTATGGGC GCTCGCTGGC GTCGCTGCTG GTTCGTGCTC 
AAGGGACACA CCCTATACTG GTACCGCCAA CCGCAGGATG AAAAGGCGGA AGGACTTATC 
AACATCTCCA ATTACAGCCT GGAGTGCGGG CATGACCAGA AGAAAAAATA TGTGTTCCAG 
CTGACCCACG ATGTGTACAA GCCCTTCATC TTTGCCTCGG AGACCCTGTC TGATCTGAGC 
ATGTGGGTGC GGCATCTTGT CACCTGCATT TCCAAGTATC AGACTCTAGG TCGGGCCCCC 
TCCGCCAGAG AGGAAGACTG CTACAGTGAG ACCGAAGCAG AAGACCCTGA TGAAGAGGCA 
GGGTCCCGCT CAGCTTCTCC TGGTCCAGCT CAAGCTTGGA ATGACACATC GCCCTCGGCT 
TCACCCCTGC AGAGTCCTAG GACCTCCTTT GGCTCTTCAT TAGATAGCAG TGACAGAGCC 
CTGGAAGGAA TGGTACAGGG GCTGAGGCAG GGAGGCGTGT CCCTCCTGGG CCAGCCACAG 
CCCTTGACCC ATGAACAGTG GCGGAGTTCT TTCATGCGGC GAAACCGTGA CCCTCATCTC 
AATGAGCATG TGCACCGTGT CCGGGCACTA CAGAGCACAC TCAAGGCAAA GCTACAGGAA 
CTGCAGGTCC TGGAGGAAGT CCTGGGTGAT CCTGAACTCA CAGGAGCAAA ATTTCGCCAG 
TGGAAGGAAC AGAACCACGA GCTGTACTCA GAAGGCCTGA GGACCTGGGG AGGGATGTGG 
GCCCAGACCA GCTCCCCAGA CCCAAACACT GACTCCAGGG GTCAATCCCC ACAGCCTCTA 
CCCTCTGACC CTGAAGAGCC CTCCCAGCTT TTTCCCTCGA CCCCAGAGAA CAGCCTCCAA 
CCTCCTGACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An ATIPical family of angiotensin II AT2 receptor-interacting proteins.
Trends in endocrinology and metabolism: TEM21(11)684-90(2010 Nov)
Rodrigues-Ferreira S,Nahmias C

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
The Journal of biological chemistry279(28)29247-54(2004 Jul)
Rabizadeh S,Xavier RJ,Ishiguro K,Bernabeortiz J,Lopez-Ilasaca M,Khokhlatchev A,Mollahan P,Pfeifer GP,Avruch J,Seed B

Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways.
Molecular and cellular biology24(4)1736-46(2004 Feb)
Jaffe AB,Aspenström P,Hall A

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Cnksr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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