Grin3b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grin3b
Entrez Gene ID	170796
Full Name	glutamate ionotropic receptor NMDA type subunit 3B
Synonyms	GluN3B,NMDAR3B,NR3B
General protein information	Preferred Names glutamate ionotropic receptor NMDA type subunit 3B Names glutamate receptor ionotropic, NMDA 3B N-methyl-D-aspartate receptor subtype 3B glutamate [NMDA] receptor subunit 3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B glutamate receptor, ionotropic, NMDA3B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	a subunit of the glutamate receptor with important roles in the central nervous system, including neuronal development, plasticity and neurodegeneration [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133308.2	NP_579842.2	glutamate receptor ionotropic, NMDA 3B precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GRIN3B	NP_619635.1
Rattus norvegicus (Norway rat)	Grin3b	NP_579842.2
Danio rerio (zebrafish)	LOC566411	XP_694772.5
Danio rerio (zebrafish)	LOC100333101	XP_002663775.3
Bos taurus (cattle)	GRIN3B	XP_002689214.2
Mus musculus (house mouse)	Grin3b	NP_569722.1
Gallus gallus (chicken)	GRIN3B	XP_426726.4
Danio rerio (zebrafish)	LOC571394	XP_700069.6
Canis lupus familiaris (dog)	GRIN3B	XP_542210.3
Xenopus tropicalis (tropical clawed frog)	grin3b	XP_002937428.1

Gene Ontology
Bibliography

Related articles in PubMed

Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses.
Berg LK, Larsson M, Morland C, Gundersen V
Neuroscience230139-50(2013 Jan)

Requirement of both NR3A and NR3B subunits for dominant negative properties on Ca2+ mobilization mediated by acquired N-methyl-D-aspartate receptor channels into mitochondria.
Fukumori R, Takarada T, Nakamichi N, Kambe Y, Kawagoe H, Nakazato R, Yoneda Y
Neurochemistry international57(7)730-7(2010 Dec)

Postnatal development of N-methyl-D-aspartate receptor subunits 2A, 2B, 2C, 2D, and 3B immunoreactivity in brain stem respiratory nuclei of the rat.
Liu Q, Wong-Riley MT
Neuroscience171(3)637-54(2010 Dec)

Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus.
Bendová Z, Sumová A, Mikkelsen JD
Neuroscience159(2)599-609(2009 Mar)

Immunolocalization of NMDA receptor subunit NR3B in selected structures in the rat forebrain, cerebellum, and lumbar spinal cord.
Wee KS, Zhang Y, Khanna S, Low CM
The Journal of comparative neurology509(1)118-35(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grin3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grin3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00588	NM_133308.2 Latest version!	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3B (Grin3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grin3b ( NM_133308.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_579842.2 Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3B (Grin3b), mRNA.

Price & Availability↑

CloneID	ORa00588
Clone ID Related Accession (Same CDS sequence)	NM_133308.2
Accession Version	NM_133308.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3009bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573660800000
Organism	Rattus norvegicus(Norway rat)
Product	glutamate receptor ionotropic, NMDA 3B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF440691.2. On May 1, 2002 this sequence version replaced NM_133308.1. ##Evidence-Data-START## Transcript exon combination :: AF440691.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04563758, SAMN04563759 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAGTG TGCGGACGCT GTGGCTCAGC GTGGCCCTGG CGCTGGCGGT GGGGTCCCGA 
GTGGTGCGCG GTCACCCTCA GCCCTGCCGG GTTCCCACGC GCGCTGGGGC CTCCGTGCGC 
CTGGCGGCGC TCCTGCCCCG GGCGCCCGCC GCCCGCGCCC GCGTCCTAGC TGCCCTGGCC 
ACCCCTGCGC CGCGGCTGCC GCACAACCTG AGTCTGGAAC TGGTGGCCGT CGCGTCCCCG 
ACCCGGGACC CCGCGTCGCT AGCTCGAGGT CTGTGCCAGG TTCTGGCACC GCCTGGCGTG 
GTGGCCTCTA TAGCCTTTCC CGAGGCGCGG CCCGAGCTGC GGCTACTGCA GTTCCTGGCA 
GCCGCCACAG AGACCCCAGT GGTGAGCGTC CTGCGGAGGG AGGTGCGCAC GGCCCTCGGA 
GCCCCGACTC CGTTCCATCT GCAGCTGGAC TGGGCTAGTC CCCTGGAGAC CATACTGGAT 
GTGCTGGTGT CCCTGGTACG GGCACATGCC TGGGAGGACA TTGCTCTAGT ACTCTGCCGT 
GTCCGGGACC CTGGCAGCCT GGTGACACTC TGGACTAACC ATGCTAGCCA GGCTCCAAAG 
TTTGTGCTGG ACCTGAGCCG GCTGGACAGC AGGAATGACA GCCTTCGGGC TGGACTGGCC 
CTGTTGGGGG CGCTGGAAGG AGGGGGAACC CCAGTGCCTG CAGCAGTCCT CCTAGGCTGC 
AGCACTGCCC GTGCACATGA GGTCCTAGAG GCTGCACCAC CGGGTCCCCA GTGGTTGCTG 
GGCACACCAT TGCCCGCTGA GGCACTGCCC ACGACTGGTC TGCCACCTGG CGTGCTGGCG 
CTGGGGGAAA CCGAACAACA CTCTCTGGAA GCTGTCGTCC ACGACATGGT GGAGCTTGTG 
GCTCAGGCAC TCAGTAGCAT GGCCCTTGTA CACCCAGAGC GGGCACTGCT TCCAGCTGTG 
GTGAACTGTG ATGACCTGAA AACAGGCGGA TCTGAGGCAA CAGGGCGCAC CTTGGCTCGG 
TTTCTCGGCA ACACCTCATT TCAGGGCCGA ACAGGGGCCG TGTGGGTGAC AGGCTCCTCT 
CAGGTGCATG TGTCTCGGCA TTTCAAGGTA TGGAGCCTGC GCCGGGATCC GCTGGGTGCC 
CCAGCCTGGG CAACCGTGGG CAGCTGGCAG GATGGACAGC TGGACTTCCA GCCAGGGGCA 
GCCGCTCTCC GAGTCCCATC TCCGTCTGGC ACCCAGGCCC GACCAAAGCT GCGTGTGGTA 
ACCCTGGTGG AACACCCGTT TGTGTTCACC AGGGAATCTG ATGAAGACGG ACAGTGCCCA 
GCTGGGCAGC TGTGTCTGGA CCCAGGCACC AATGACTCAG CCAGGCTGGA TGCCCTCTTT 
GCTGCACTGG TGAATGGCTC AGTACCTCGA ACGCTGAGAA GATGCTGCTA TGGCTACTGC 
ATCGACCTGC TGGAGCGGCT GGCCGAGGAC CTGGCCTTTG ACTTTGAGCT CTATATTGTG 
GGGGATGGCA AGTACGGGGC CCTGCGTGAT GGGCGCTGGA CGGGCCTGGT GGGTGACCTG 
CTGGCTGGCC GGGCACACAT GGCTGTGACC AGCTTCAGCA TCAACTCAGC TCGCTCTCAG 
GTGGTGGATT TCACCAGCCC TTTCTTCTCC ACCAGCCTGG GGATTATGGT GCGCACGAGA 
GACACGGCCT CGCCCATCGG GGCTTTCATG TGGCCCCTGC ACTGGTCCAT GTGGGTGGGC 
GTGTTTGCTG CTCTGCACCT CACAGCGCTC TTTCTCACCC TGTACGAATG GCGAAGTCCC 
TACGGGCTCA CGCCGCGCGG CCGCAACCGT GGCACTGTCT TCTCTTACTC CTCCGCGCTC 
AACCTGTGCT ATGCCATTCT CTTTGGACGC ACTGTCTCCA GTAAGACGCC CAAGTGCCCT 
ACTGGACGCT TCCTCATGAA CCTCTGGGCA ATCTTCTGCC TGCTGGTGCT TTCCAGTTAC 
ACGGCCAACC TGGCTGCTGT CATGGTTGGG GACAAAACCT TTGAGGAGCT GTCTGGAATC 
CATGATCCCA AGCTGCACCA CCCTTCCCAA GGCTTTCGCT TTGGCACCGT ATGGGAGAGC 
AGCGCGGAGG CCTACATCAA GGCAAGCTTC CCTGAGATGC ACGCACACAT GCGTCGGCAC 
AGCGCACCCA CCACTCCACA TGGGGTGGCC ATGCTCACGA GCGACCCGCC CAAGCTCAAC 
GCCTTCATCA TGGATAAATC ACTACTGGAC TATGAGGTGT CCATAGATGC GGACTGCAAG 
CTGCTCACCG TTGGCAAACC CTTTGCTATC GAGGGCTACG GCATAGGGCT ACCCCAAAAC 
TCGCCGCTCA CCTCCAACCT GTCGGAGTTC ATCAGTAGGT ACAAGTCTTC AGGCTTCATT 
GATCTGCTCC ATGACAAGTG GTACAAGATG GTGCCTTGCG GGAAGCGGGT GTTCGCCGTG 
ACGGAGACGC TGCAGATGGG GGTCTACCAC TTCTCAGGAT TGTTTGTCCT GCTGTGCCTC 
GGGCTGGGCA GCGCGCTTCT CACCTCTCTG GGTGAGCATG TCTTCTACCG CCTGGTGCTG 
CCGCGCATCC GCAGGGGTAA TAAGCTGCAG TATTGGCTTC ACACGAGCCA GAAGATCCAC 
CGAGCCCTCA ATACAGGACC ACCCGAGGGG CAACAGGAGA GGGCAGAGCA GGAGCGCAGC 
GGCCCCAAGG ACGAGCTGCC TGCCACCGAT GGTGCAGGGC GCTGGAGGCG GGTGCGCCGG 
GCTGTGGAAC GGGAGCGACG CGTGCGTTTC CTGCTGGAAC CTGGGGAGGC TGGCGGAGAC 
CGCCCGTGGC TCTGCTCCAA CGGGCCCGGG CTGCAAGCGG AGCTGCGGGA GCTGGAGCTG 
CGCATTGAGG CTGCACGGGA GCGGCTGCGC AGTGCGCTGT TGCGGCGCGG GGAGCTGCGG 
GCCCTGCTTG GGGATGGCAC CCGGCTCAGG CCACTGCGCC TGTTGCATGC GGCGCCTGCT 
GAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_579842.2
CDS	76..3084
Translation	MESVRTLWLSVALALAVGSRVVRGHPQPCRVPTRAGASVRLAALLPRAPAARARVLAALATPAPRLPHNLSLELVAVASPTRDPASLARGLCQVLAPPGVVASIAFPEARPELRLLQFLAAATETPVVSVLRREVRTALGAPTPFHLQLDWASPLETILDVLVSLVRAHAWEDIALVLCRVRDPGSLVTLWTNHASQAPKFVLDLSRLDSRNDSLRAGLALLGALEGGGTPVPAAVLLGCSTARAHEVLEAAPPGPQWLLGTPLPAEALPTTGLPPGVLALGETEQHSLEAVVHDMVELVAQALSSMALVHPERALLPAVVNCDDLKTGGSEATGRTLARFLGNTSFQGRTGAVWVTGSSQVHVSRHFKVWSLRRDPLGAPAWATVGSWQDGQLDFQPGAAALRVPSPSGTQARPKLRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPRTLRRCCYGYCIDLLERLAEDLAFDFELYIVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRDTASPIGAFMWPLHWSMWVGVFAALHLTALFLTLYEWRSPYGLTPRGRNRGTVFSYSSALNLCYAILFGRTVSSKTPKCPTGRFLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMGVYHFSGLFVLLCLGLGSALLTSLGEHVFYRLVLPRIRRGNKLQYWLHTSQKIHRALNTGPPEGQQERAEQERSGPKDELPATDGAGRWRRVRRAVERERRVRFLLEPGEAGGDRPWLCSNGPGLQAELRELELRIEAARERLRSALLRRGELRALLGDGTRLRPLRLLHAAPAES

Target ORF information:

RefSeq Version	NM_133308.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3B (Grin3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133308.2

ORF Insert Sequence:

ATGGAGAGTG TGCGGACGCT GTGGCTCAGC GTGGCCCTGG CGCTGGCGGT GGGGTCCCGA 
GTGGTGCGCG GTCACCCTCA GCCCTGCCGG GTTCCCACGC GCGCTGGGGC CTCCGTGCGC 
CTGGCGGCGC TCCTGCCCCG GGCGCCCGCC GCCCGCGCCC GCGTCCTAGC TGCCCTGGCC 
ACCCCTGCGC CGCGGCTGCC GCACAACCTG AGTCTGGAAC TGGTGGCCGT CGCGTCCCCG 
ACCCGGGACC CCGCGTCGCT AGCTCGAGGT CTGTGCCAGG TTCTGGCACC GCCTGGCGTG 
GTGGCCTCTA TAGCCTTTCC CGAGGCGCGG CCCGAGCTGC GGCTACTGCA GTTCCTGGCA 
GCCGCCACAG AGACCCCAGT GGTGAGCGTC CTGCGGAGGG AGGTGCGCAC GGCCCTCGGA 
GCCCCGACTC CGTTCCATCT GCAGCTGGAC TGGGCTAGTC CCCTGGAGAC CATACTGGAT 
GTGCTGGTGT CCCTGGTACG GGCACATGCC TGGGAGGACA TTGCTCTAGT ACTCTGCCGT 
GTCCGGGACC CTGGCAGCCT GGTGACACTC TGGACTAACC ATGCTAGCCA GGCTCCAAAG 
TTTGTGCTGG ACCTGAGCCG GCTGGACAGC AGGAATGACA GCCTTCGGGC TGGACTGGCC 
CTGTTGGGGG CGCTGGAAGG AGGGGGAACC CCAGTGCCTG CAGCAGTCCT CCTAGGCTGC 
AGCACTGCCC GTGCACATGA GGTCCTAGAG GCTGCACCAC CGGGTCCCCA GTGGTTGCTG 
GGCACACCAT TGCCCGCTGA GGCACTGCCC ACGACTGGTC TGCCACCTGG CGTGCTGGCG 
CTGGGGGAAA CCGAACAACA CTCTCTGGAA GCTGTCGTCC ACGACATGGT GGAGCTTGTG 
GCTCAGGCAC TCAGTAGCAT GGCCCTTGTA CACCCAGAGC GGGCACTGCT TCCAGCTGTG 
GTGAACTGTG ATGACCTGAA AACAGGCGGA TCTGAGGCAA CAGGGCGCAC CTTGGCTCGG 
TTTCTCGGCA ACACCTCATT TCAGGGCCGA ACAGGGGCCG TGTGGGTGAC AGGCTCCTCT 
CAGGTGCATG TGTCTCGGCA TTTCAAGGTA TGGAGCCTGC GCCGGGATCC GCTGGGTGCC 
CCAGCCTGGG CAACCGTGGG CAGCTGGCAG GATGGACAGC TGGACTTCCA GCCAGGGGCA 
GCCGCTCTCC GAGTCCCATC TCCGTCTGGC ACCCAGGCCC GACCAAAGCT GCGTGTGGTA 
ACCCTGGTGG AACACCCGTT TGTGTTCACC AGGGAATCTG ATGAAGACGG ACAGTGCCCA 
GCTGGGCAGC TGTGTCTGGA CCCAGGCACC AATGACTCAG CCAGGCTGGA TGCCCTCTTT 
GCTGCACTGG TGAATGGCTC AGTACCTCGA ACGCTGAGAA GATGCTGCTA TGGCTACTGC 
ATCGACCTGC TGGAGCGGCT GGCCGAGGAC CTGGCCTTTG ACTTTGAGCT CTATATTGTG 
GGGGATGGCA AGTACGGGGC CCTGCGTGAT GGGCGCTGGA CGGGCCTGGT GGGTGACCTG 
CTGGCTGGCC GGGCACACAT GGCTGTGACC AGCTTCAGCA TCAACTCAGC TCGCTCTCAG 
GTGGTGGATT TCACCAGCCC TTTCTTCTCC ACCAGCCTGG GGATTATGGT GCGCACGAGA 
GACACGGCCT CGCCCATCGG GGCTTTCATG TGGCCCCTGC ACTGGTCCAT GTGGGTGGGC 
GTGTTTGCTG CTCTGCACCT CACAGCGCTC TTTCTCACCC TGTACGAATG GCGAAGTCCC 
TACGGGCTCA CGCCGCGCGG CCGCAACCGT GGCACTGTCT TCTCTTACTC CTCCGCGCTC 
AACCTGTGCT ATGCCATTCT CTTTGGACGC ACTGTCTCCA GTAAGACGCC CAAGTGCCCT 
ACTGGACGCT TCCTCATGAA CCTCTGGGCA ATCTTCTGCC TGCTGGTGCT TTCCAGTTAC 
ACGGCCAACC TGGCTGCTGT CATGGTTGGG GACAAAACCT TTGAGGAGCT GTCTGGAATC 
CATGATCCCA AGCTGCACCA CCCTTCCCAA GGCTTTCGCT TTGGCACCGT ATGGGAGAGC 
AGCGCGGAGG CCTACATCAA GGCAAGCTTC CCTGAGATGC ACGCACACAT GCGTCGGCAC 
AGCGCACCCA CCACTCCACA TGGGGTGGCC ATGCTCACGA GCGACCCGCC CAAGCTCAAC 
GCCTTCATCA TGGATAAATC ACTACTGGAC TATGAGGTGT CCATAGATGC GGACTGCAAG 
CTGCTCACCG TTGGCAAACC CTTTGCTATC GAGGGCTACG GCATAGGGCT ACCCCAAAAC 
TCGCCGCTCA CCTCCAACCT GTCGGAGTTC ATCAGTAGGT ACAAGTCTTC AGGCTTCATT 
GATCTGCTCC ATGACAAGTG GTACAAGATG GTGCCTTGCG GGAAGCGGGT GTTCGCCGTG 
ACGGAGACGC TGCAGATGGG GGTCTACCAC TTCTCAGGAT TGTTTGTCCT GCTGTGCCTC 
GGGCTGGGCA GCGCGCTTCT CACCTCTCTG GGTGAGCATG TCTTCTACCG CCTGGTGCTG 
CCGCGCATCC GCAGGGGTAA TAAGCTGCAG TATTGGCTTC ACACGAGCCA GAAGATCCAC 
CGAGCCCTCA ATACAGGACC ACCCGAGGGG CAACAGGAGA GGGCAGAGCA GGAGCGCAGC 
GGCCCCAAGG ACGAGCTGCC TGCCACCGAT GGTGCAGGGC GCTGGAGGCG GGTGCGCCGG 
GCTGTGGAAC GGGAGCGACG CGTGCGTTTC CTGCTGGAAC CTGGGGAGGC TGGCGGAGAC 
CGCCCGTGGC TCTGCTCCAA CGGGCCCGGG CTGCAAGCGG AGCTGCGGGA GCTGGAGCTG 
CGCATTGAGG CTGCACGGGA GCGGCTGCGC AGTGCGCTGT TGCGGCGCGG GGAGCTGCGG 
GCCCTGCTTG GGGATGGCAC CCGGCTCAGG CCACTGCGCC TGTTGCATGC GGCGCCTGCT 
GAGAGCTGA