CGA cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	CGA
Entrez Gene ID	443538
Full Name	glycoprotein hormones, alpha polypeptide
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009464.1	NP_001009464.1	glycoprotein hormones alpha chain precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.
Shuhaibar LC, Egbert JR, Edmund AB, Uliasz TF, Dickey DM, Yee SP, Potter LR, Jaffe LA
Developmental biology409(1)194-201(2016 Jan)

Effect of phytoestrogens on basal and GnRH-induced gonadotropin secretion.
Arispe SA, Adams B, Adams TE
The Journal of endocrinology219(3)243-50(2013 Dec)

Potential role of follicle-stimulating hormone (FSH) and transforming growth factor (TGFβ1) in the regulation of ovarian angiogenesis.
Kuo SW, Ke FC, Chang GD, Lee MT, Hwang JJ
Journal of cellular physiology226(6)1608-19(2011 Jun)

Primary structure of the ovine pituitary follitropin alpha-subunit.
Sairam MR
The Biochemical journal197(3)535-9(1981 Sep)

The primary structure of ovine luteinizing hormone. I. The amino acid sequence of the reduced and S-aminoethylated S-subunit (LH- ).
Liu WK, Nahm HS, Sweeney CM, Lamkin WM, Baker HN, Ward DN
The Journal of biological chemistry247(13)4351-64(1972 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CGA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CGA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm21555	NM_001009464.1 Latest version!	Ovis aries glycoprotein hormones, alpha polypeptide (CGA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CGA ( NM_001009464.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001009464.1 Ovis aries glycoprotein hormones, alpha polypeptide (CGA), mRNA.

Price & Availability↑

CloneID	OSm21555
Clone ID Related Accession (Same CDS sequence)	NM_001009464.1
Accession Version	NM_001009464.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Ovis aries(sheep)
Product	glycoprotein hormones alpha chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X16977.1. ##Evidence-Data-START## Transcript exon combination :: X16977.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA104495017 [ECO:0000350] ##Evidence-Data-END##

ATGGATTACT ACAGAAAGTA TGCAGCTGCC ATTCTGGCCA TATTGTCTCT GTTTCTGCAA 
ATTCTCCATT CCTTTCCTGA TGGAGAGTTT ACAATGCAGG GTTGTCCTGA ATGCAAGCTA 
AAAGAAAACA AATACTTCTC CAAGCCAGAT GCTCCAATTT ATCAGTGCAT GGGGTGCTGC 
TTCTCCAGGG CATACCCCAC TCCAGCGAGG TCTAAGAAGA CAATGTTGGT TCCCAAGAAC 
ATCACCTCGG AAGCCACATG TTGTGTGGCC AAAGCATTTA CCAAGGCCAC AGTGATGGGA 
AATGTCAGAG TGGAGAACCA CACCGAGTGC CACTGCAGTA CTTGTTATTA TCACAAATCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009464.1
CDS	71..433
Translation	MDYYRKYAAAILAILSLFLQILHSFPDGEFTMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNVRVENHTECHCSTCYYHKS

Target ORF information:

RefSeq Version	NM_001009464.1
Organism	Ovis aries(sheep)
Definition	Ovis aries glycoprotein hormones, alpha polypeptide (CGA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009464.1

ORF Insert Sequence:

ATGGATTACT ACAGAAAGTA TGCAGCTGCC ATTCTGGCCA TATTGTCTCT GTTTCTGCAA 
ATTCTCCATT CCTTTCCTGA TGGAGAGTTT ACAATGCAGG GTTGTCCTGA ATGCAAGCTA 
AAAGAAAACA AATACTTCTC CAAGCCAGAT GCTCCAATTT ATCAGTGCAT GGGGTGCTGC 
TTCTCCAGGG CATACCCCAC TCCAGCGAGG TCTAAGAAGA CAATGTTGGT TCCCAAGAAC 
ATCACCTCGG AAGCCACATG TTGTGTGGCC AAAGCATTTA CCAAGGCCAC AGTGATGGGA 
AATGTCAGAG TGGAGAACCA CACCGAGTGC CACTGCAGTA CTTGTTATTA TCACAAATCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.
Developmental biology409(1)194-201(2016 Jan)
Shuhaibar LC,Egbert JR,Edmund AB,Uliasz TF,Dickey DM,Yee SP,Potter LR,Jaffe LA

Effect of phytoestrogens on basal and GnRH-induced gonadotropin secretion.
The Journal of endocrinology219(3)243-50(2013 Dec)
Arispe SA,Adams B,Adams TE

Potential role of follicle-stimulating hormone (FSH) and transforming growth factor (TGFβ1) in the regulation of ovarian angiogenesis.
Journal of cellular physiology226(6)1608-19(2011 Jun)
Kuo SW,Ke FC,Chang GD,Lee MT,Hwang JJ

Primary structure of the ovine pituitary follitropin alpha-subunit.
The Biochemical journal197(3)535-9(1981 Sep)
Sairam MR

The primary structure of ovine luteinizing hormone. I. The amino acid sequence of the reduced and S-aminoethylated S-subunit (LH- ).
The Journal of biological chemistry247(13)4351-64(1972 Jul)
Liu WK,Nahm HS,Sweeney CM,Lamkin WM,Baker HN,Ward DN