Gene Symbol | GHR |
Entrez Gene ID | 100009325 |
Full Name | growth hormone receptor |
Gene Type | protein-coding |
Organism | Oryctolagus cuniculus(rabbit) |
ORF » Species Summary » Oryctolagus cuniculus » GHR cDNA ORF clone
Gene Symbol | GHR |
Entrez Gene ID | 100009325 |
Full Name | growth hormone receptor |
Gene Type | protein-coding |
Organism | Oryctolagus cuniculus(rabbit) |
mRNA | Protein | Name |
---|---|---|
XM_017344510.1 | XP_017199999.1 | growth hormone receptor isoform X1 |
XM_008262052.2 | XP_008260274.2 | growth hormone receptor isoform X2 |
XM_008262047.2 | XP_008260269.1 | growth hormone receptor isoform X1 |
XM_017344508.1 | XP_017199997.1 | growth hormone receptor isoform X1 |
XM_008262049.2 | XP_008260271.1 | growth hormone receptor isoform X1 |
NM_001082636.1 | NP_001076105.1 | growth hormone receptor precursor |
XM_008262046.2 | XP_008260268.1 | growth hormone receptor isoform X1 |
XM_008262048.2 | XP_008260270.1 | growth hormone receptor isoform X1 |
XM_008262050.2 | XP_008260272.1 | growth hormone receptor isoform X1 |
Fos-Zippered GH Receptor Cytosolic Tails Act as Jak2 Substrates and Signal Transducers.
Nespital T, van der Velden LM, Mensinga A, van der Vaart ED, Strous GJ
Molecular endocrinology (Baltimore, Md.)30(3)290-301(2016 Mar)
Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor.
Putters J, da Silva Almeida AC, van Kerkhof P, van Rossum AG, Gracanin A, Strous GJ
PloS one6(2)e14676(2011 Feb)
[The correlations between polymorphism of growth hormone receptor gene and butcher traits in rabbit].
Deng XS, Wan J, Chen SY, Wang Y, Lai SJ, Jiang MS, Xu M
Yi chuan = Hereditas30(11)1427-32(2008 Nov)
The growth hormone receptor interacts with its sheddase, the tumour necrosis factor-alpha-converting enzyme (TACE).
Schantl JA, Roza M, Van Kerkhof P, Strous GJ
The Biochemical journal377(Pt 2)379-84(2004 Jan)
Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2.
Alves dos Santos CM, ten Broeke T, Strous GJ
The Journal of biological chemistry276(35)32635-41(2001 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following GHR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GHR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OOb34936 | |
Clone ID Related Accession (Same CDS sequence) | XM_008262052.2 | |
Accession Version | XM_008262052.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262052.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTGTAT GTGGTCCTAC AGGTATGGAT CTCTGGCAGC TGCTGTTGAC CGTGGCACTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260274.2 |
CDS | 7..921 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGTTGTAT GTGGTCCTAC AGGTATGGAT CTCTGGCAGC TGCTGTTGAC CGTGGCACTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb00185 | |
Clone ID Related Accession (Same CDS sequence) | NM_001082636.1 | |
Accession Version | NM_001082636.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1569081600000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF015252.1. ##Evidence-Data-START## Transcript exon combination :: AF015252.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3321799, SAMEA3321800 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076105.1 |
CDS | 145..2061 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_017344510.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017199999.1 |
CDS | 184..2100 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_008262047.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262047.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260269.1 |
CDS | 280..2196 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_017344508.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017199997.1 |
CDS | 329..2245 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_008262049.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262049.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260271.1 |
CDS | 115..2031 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_008262046.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262046.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260268.1 |
CDS | 333..2249 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_008262048.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262048.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260270.1 |
CDS | 188..2104 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OOb11170 | |
Clone ID Related Accession (Same CDS sequence) | XM_017344510.1 , XM_008262047.2 , XM_017344508.1 , XM_008262049.2 , XM_008262046.2 , XM_008262048.2 , XM_008262050.2 | |
Accession Version | XM_008262050.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1466524800000 | |
Organism | Oryctolagus cuniculus(rabbit) | |
Product | growth hormone receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013679.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008262050.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008260272.1 |
CDS | 135..2051 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATCTCT GGCAGCTGCT GTTGACCGTG GCACTAGCAG GGTCAAGTGA TGCTTTTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Fos-Zippered GH Receptor Cytosolic Tails Act as Jak2 Substrates and Signal Transducers. |
Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor. |
[The correlations between polymorphism of growth hormone receptor gene and butcher traits in rabbit]. |
The growth hormone receptor interacts with its sheddase, the tumour necrosis factor-alpha-converting enzyme (TACE). |
Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2. |