Ackr4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ackr4
Entrez Gene ID	252837
Full Name	atypical chemokine receptor 4
Synonyms	A630091E18Rik,CCBP2,CCR11,CCX-CKR,CCX-CKR1,Ccrl1,Cmkbrl1,PPR1,VSHK1
General protein information	Preferred Names atypical chemokine receptor 4 Names atypical chemokine receptor 4 C-C CKR-11 C-C chemokine receptor type 11 CC chemokine receptor-like 1 CC-CKR-11 CCR-11 CCX CKR chemokine (C-C motif) receptor-like 1 chemokine (C-C) receptor-like 1 chemokine receptor CCR11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006511735.3	XP_006511798.1	atypical chemokine receptor 4 isoform X1
NM_145700.2	NP_663746.2	atypical chemokine receptor 4
XM_006511734.3	XP_006511797.1	atypical chemokine receptor 4 isoform X1
XM_006511735.4	XP_006511798.1	atypical chemokine receptor 4 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCRL1	XP_001150177.1
Bos taurus (cattle)	ACKR4	NP_776690.1
Mus musculus (house mouse)	Ackr4	NP_663746.2
Homo sapiens (human)	ACKR4	NP_057641.1
Rattus norvegicus (Norway rat)	Ackr4	XP_003750626.1
Danio rerio (zebrafish)	ackr4b	XP_005162666.1
Canis lupus familiaris (dog)	ACKR4	XP_005634482.1
Xenopus tropicalis (tropical clawed frog)	ccrl1	XP_002937785.1
Macaca mulatta (Rhesus monkey)	CCRL1	XP_001115475.1
Danio rerio (zebrafish)	si:ch211-106h4.12	XP_005163521.1
Gallus gallus (chicken)	CCRL1	XP_003640769.2

Gene Ontology
Bibliography

Related articles in PubMed

Multiple roles of lymphatic vessels in peripheral lymph node development.
Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV
The Journal of experimental medicine215(11)2760-2777(2018 11)

Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators.
Thomson CA, van de Pavert SA, Stakenborg M, Labeeuw E, Matteoli G, Mowat AM, Nibbs RJB
Journal of immunology (Baltimore, Md. : 1950)201(1)215-229(2018 07)

Atypical chemokine receptor 4 shapes activated B cell fate.
Kara EE, Bastow CR, McKenzie DR, Gregor CE, Fenix KA, Babb R, Norton TS, Zotos D, Rodda LB, Hermes JR, Bourne K, Gilchrist DS, Nibbs RJ, Alsharifi M, Vinuesa CG, Tarlinton DM, Brink R, Hill GR, Cyster JG, Comerford I, McColl SR
The Journal of experimental medicine215(3)801-813(2018 03)

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade.
Rodrigues PM, Ribeiro AR, Serafini N, Meireles C, Di Santo JP, Alves NL
Journal of immunology (Baltimore, Md. : 1950)200(4)1389-1398(2018 02)

A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4.
Jafarnejad M, Zawieja DC, Brook BS, Nibbs RJB, Moore JE Jr
Journal of immunology (Baltimore, Md. : 1950)199(7)2291-2304(2017 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ackr4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ackr4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11945	NM_145700.2 Latest version!	Mus musculus atypical chemokine receptor 4 (Ackr4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu11945	XM_006511734.3 Latest version!	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu11945	XM_006511735.4 Latest version!	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu11945	XM_006511735.3	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ackr4 ( NM_145700.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663746.2 Mus musculus atypical chemokine receptor 4 (Ackr4), mRNA.

Price & Availability↑

CloneID	OMu11945
Clone ID Related Accession (Same CDS sequence)	XM_006511735.3 , NM_145700.2 , XM_006511734.3 , XM_006511735.4
Accession Version	NM_145700.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	atypical chemokine receptor 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC140999.1, AC145736.4, AK042430.1, AK030643.1 and BB151172.1. On Mar 27, 2009 this sequence version replaced NM_145700.1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC140999.1, AY072938.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849389 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663746.2
CDS	501..1553
Translation	MALELNQSAEYYYEENEMNYTHDYSQYEVICIKEEVRQFAKVFLPAFFTVAFVTGLAGNSVVVAIYAYYKKQRTKTDVYILNLAVADLLLLITLPFWAVNAVHGWILGKMMCKVTSALYTVNFVSGMQFLACISIDRYWAITKAPSQSGAGRPCWIICCCVWMAAILLSIPQLVFYTVNQNARCTPIFPHHLGTSLKASIQMLEIGIGFVVPFLIMGVCYASTARALIKMPNIKKSRPLRVLLAVVVVFIVTQLPYNVVKFCQAIDAIYLLITSCDMSKRMDVAIQVTESIALFHSCLNPILYVFMGASFKNYIMKVAKKYGSWRRQRQNVEEIPFDSEGPTEPTSSFTI

Target ORF information:

RefSeq Version	NM_145700.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus atypical chemokine receptor 4 (Ackr4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145700.2

ORF Insert Sequence:

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ackr4 ( XM_006511735.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511798.1 Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu11945
Clone ID Related Accession (Same CDS sequence)	XM_006511735.3 , NM_145700.2 , XM_006511734.3 , XM_006511735.4
Accession Version	XM_006511735.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	atypical chemokine receptor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511735.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511798.1
CDS	3189..4241
Translation	MALELNQSAEYYYEENEMNYTHDYSQYEVICIKEEVRQFAKVFLPAFFTVAFVTGLAGNSVVVAIYAYYKKQRTKTDVYILNLAVADLLLLITLPFWAVNAVHGWILGKMMCKVTSALYTVNFVSGMQFLACISIDRYWAITKAPSQSGAGRPCWIICCCVWMAAILLSIPQLVFYTVNQNARCTPIFPHHLGTSLKASIQMLEIGIGFVVPFLIMGVCYASTARALIKMPNIKKSRPLRVLLAVVVVFIVTQLPYNVVKFCQAIDAIYLLITSCDMSKRMDVAIQVTESIALFHSCLNPILYVFMGASFKNYIMKVAKKYGSWRRQRQNVEEIPFDSEGPTEPTSSFTI

Target ORF information:

RefSeq Version	XM_006511735.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511735.3

ORF Insert Sequence:

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ackr4 ( XM_006511734.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511797.1 Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu11945
Clone ID Related Accession (Same CDS sequence)	XM_006511735.3 , NM_145700.2 , XM_006511734.3 , XM_006511735.4
Accession Version	XM_006511734.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	atypical chemokine receptor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511734.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511797.1
CDS	3443..4495
Translation	MALELNQSAEYYYEENEMNYTHDYSQYEVICIKEEVRQFAKVFLPAFFTVAFVTGLAGNSVVVAIYAYYKKQRTKTDVYILNLAVADLLLLITLPFWAVNAVHGWILGKMMCKVTSALYTVNFVSGMQFLACISIDRYWAITKAPSQSGAGRPCWIICCCVWMAAILLSIPQLVFYTVNQNARCTPIFPHHLGTSLKASIQMLEIGIGFVVPFLIMGVCYASTARALIKMPNIKKSRPLRVLLAVVVVFIVTQLPYNVVKFCQAIDAIYLLITSCDMSKRMDVAIQVTESIALFHSCLNPILYVFMGASFKNYIMKVAKKYGSWRRQRQNVEEIPFDSEGPTEPTSSFTI

Target ORF information:

RefSeq Version	XM_006511734.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511734.3

ORF Insert Sequence:

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ackr4 ( XM_006511735.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511798.1 Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu11945
Clone ID Related Accession (Same CDS sequence)	XM_006511735.3 , NM_145700.2 , XM_006511734.3 , XM_006511735.4
Accession Version	XM_006511735.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	atypical chemokine receptor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006511735.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511798.1
CDS	418..1470
Translation	MALELNQSAEYYYEENEMNYTHDYSQYEVICIKEEVRQFAKVFLPAFFTVAFVTGLAGNSVVVAIYAYYKKQRTKTDVYILNLAVADLLLLITLPFWAVNAVHGWILGKMMCKVTSALYTVNFVSGMQFLACISIDRYWAITKAPSQSGAGRPCWIICCCVWMAAILLSIPQLVFYTVNQNARCTPIFPHHLGTSLKASIQMLEIGIGFVVPFLIMGVCYASTARALIKMPNIKKSRPLRVLLAVVVVFIVTQLPYNVVKFCQAIDAIYLLITSCDMSKRMDVAIQVTESIALFHSCLNPILYVFMGASFKNYIMKVAKKYGSWRRQRQNVEEIPFDSEGPTEPTSSFTI

Target ORF information:

RefSeq Version	XM_006511735.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus atypical chemokine receptor 4 (Ackr4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511735.4

ORF Insert Sequence:

ATGGCTCTGG AGCTGAACCA GTCAGCGGAA TACTATTATG AGGAGAATGA GATGAACTAC 
ACTCACGACT ACAGCCAGTA CGAAGTGATC TGCATAAAAG AAGAGGTCAG GCAGTTCGCA 
AAAGTCTTCC TGCCTGCCTT CTTCACAGTG GCCTTTGTCA CTGGGCTCGC AGGGAACTCC 
GTAGTTGTGG CGATTTACGC CTATTACAAG AAGCAGAGGA CCAAGACCGA TGTGTACATC 
CTGAACCTGG CTGTAGCAGA CTTGTTACTT CTGATCACGC TGCCTTTCTG GGCAGTTAAT 
GCAGTTCACG GATGGATTCT AGGCAAAATG ATGTGCAAAG TAACGTCAGC CCTGTACACG 
GTAAACTTTG TCTCTGGGAT GCAGTTCCTG GCTTGTATCA GCATTGACAG ATATTGGGCA 
ATTACCAAAG CCCCCAGCCA ATCAGGAGCG GGGAGACCCT GTTGGATCAT CTGTTGCTGT 
GTGTGGATGG CCGCCATCTT GCTGAGCATA CCCCAGCTGG TTTTTTACAC AGTGAATCAG 
AATGCTAGGT GCACTCCCAT CTTTCCCCAC CACCTAGGAA CATCCCTGAA AGCATCCATT 
CAGATGCTGG AAATCGGCAT CGGCTTTGTG GTCCCGTTTC TCATCATGGG CGTGTGCTAT 
GCCAGTACCG CCAGGGCGCT CATCAAGATG CCCAACATTA AAAAGTCTCG CCCCCTCAGG 
GTTCTGCTCG CGGTGGTGGT GGTTTTCATT GTCACCCAGC TGCCCTATAA CGTTGTTAAG 
TTCTGCCAAG CCATAGATGC CATCTACCTG CTGATCACCA GCTGCGATAT GAGCAAACGC 
ATGGATGTCG CCATCCAAGT CACAGAGAGC ATCGCGCTCT TCCACAGCTG CCTCAACCCC 
ATCCTGTATG TCTTCATGGG GGCCTCCTTC AAAAACTATA TCATGAAAGT GGCCAAGAAA 
TATGGATCCT GGAGAAGACA GAGACAGAAC GTGGAAGAAA TTCCTTTTGA TTCTGAGGGT 
CCTACAGAGC CAACCAGTTC TTTTACCATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multiple roles of lymphatic vessels in peripheral lymph node development.
The Journal of experimental medicine215(11)2760-2777(2018 11)
Bovay E,Sabine A,Prat-Luri B,Kim S,Son K,Willrodt AH,Olsson C,Halin C,Kiefer F,Betsholtz C,Jeon NL,Luther SA,Petrova TV

Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators.
Journal of immunology (Baltimore, Md. : 1950)201(1)215-229(2018 07)
Thomson CA,van de Pavert SA,Stakenborg M,Labeeuw E,Matteoli G,Mowat AM,Nibbs RJB

Atypical chemokine receptor 4 shapes activated B cell fate.
The Journal of experimental medicine215(3)801-813(2018 03)
Kara EE,Bastow CR,McKenzie DR,Gregor CE,Fenix KA,Babb R,Norton TS,Zotos D,Rodda LB,Hermes JR,Bourne K,Gilchrist DS,Nibbs RJ,Alsharifi M,Vinuesa CG,Tarlinton DM,Brink R,Hill GR,Cyster JG,Comerford I,McColl SR

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade.
Journal of immunology (Baltimore, Md. : 1950)200(4)1389-1398(2018 02)
Rodrigues PM,Ribeiro AR,Serafini N,Meireles C,Di Santo JP,Alves NL

A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4.
Journal of immunology (Baltimore, Md. : 1950)199(7)2291-2304(2017 10)
Jafarnejad M,Zawieja DC,Brook BS,Nibbs RJB,Moore JE Jr

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Ackr4 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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