B4gat1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	B4gat1
Entrez Gene ID	108902
Full Name	beta-1,4-glucuronyltransferase 1
Synonyms	1500032M01Rik,B3gnt1,B3gnt6,BETA3GNT1,iGAT,iGNT
General protein information	Preferred Names beta-1,4-glucuronyltransferase 1 Names beta-1,4-glucuronyltransferase 1 I-beta-1,3-N-acetylglucosaminyltransferase N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 poly-N-acetyllactosamine extension enzyme
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_175383.2	NP_780592.1	beta-1,4-glucuronyltransferase 1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	B3GNT1	XP_001110420.1
Danio rerio (zebrafish)	b3gnt1	NP_001265757.1
Homo sapiens (human)	B3GNT1	NP_006867.1
Bos taurus (cattle)	B3GNT1	NP_001029980.1
Mus musculus (house mouse)	B3gnt1	NP_780592.1
Rattus norvegicus (Norway rat)	LOC100911750	XP_003749084.1
Xenopus tropicalis (tropical clawed frog)	b3gnt1	XP_002939368.1
Pan troglodytes (chimpanzee)	B3GNT1	XP_508571.2
Rattus norvegicus (Norway rat)	B3gnt1	NP_001099794.1
Drosophila melanogaster (fruit fly)	CG3253	NP_611886.1
Canis lupus familiaris (dog)	B3GNT1	XP_533222.4

Gene Ontology
Bibliography

Related articles in PubMed

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation.
Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, Beltrán Valero de Bernabé D, Yu L, Wright KM, Campbell KP
eLife3(2014 Oct)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.
Yagi H, Nakagawa N, Saito T, Kiyonari H, Abe T, Toda T, Wu SW, Khoo KH, Oka S, Kato K
Scientific reports33288(2013 Nov)

Dystroglycan organizes axon guidance cue localization and axonal pathfinding.
Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L, Ginty DD
Neuron76(5)931-44(2012 Dec)

Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.
Arata-Kawai H, Singer MS, Bistrup A, Zante Av, Wang YQ, Ito Y, Bao X, Hemmerich S, Fukuda M, Rosen SD
The American journal of pathology178(1)423-33(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following B4gat1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the B4gat1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu05279	NM_175383.2 Latest version!	Mus musculus beta-1,4-glucuronyltransferase 1 (B4gat1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

B4gat1 ( NM_175383.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780592.1 Mus musculus beta-1,4-glucuronyltransferase 1 (B4gat1), mRNA.

Price & Availability↑

CloneID	OMu05279
Clone ID Related Accession (Same CDS sequence)	NM_175383.2
Accession Version	NM_175383.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	beta-1,4-glucuronyltransferase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158899.1 and AV344651.1. On Apr 15, 2006 this sequence version replaced NM_175383.1. ##Evidence-Data-START## Transcript exon combination :: AK158899.1, AK050347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAAATGT CCTACGCCAT CCGATGCGCC TTCTACCAGC TGCTGCTGGC CGCGCTCATG 
TTGGTGGCAA TGCTGCAGCT GCTCTACCTA TCGCTGCTCT CTGGACTGCA CGGCCAGGAG 
GAGCAGGAAC AGTATTTCGA GTTCTTCCCG CCGTCTCCGC GATCCGTAGA CCAGGTAAAG 
TCTCAACTCC GCACCGCACT GGCCTCCGGA GGCGTTCTAG ATGCCAGCGG CGATTATCGC 
GTCTACAGGG GTCTATTGAA GACCACCATG GACCCCAACG ATGTCATCTT AGCTACGCAT 
GCCAGTGTGG ACAACCTACT ACACCTGTCC GGACTTCTGG AGCGCTGGGA GGGTCCGCTG 
TCCGTTTCAG TGTTCGCGGC CACCAAAGAG GAGGCGCAGC TGGCCACGGT GCTGGCCTAC 
GCGCTGAGTA GCCACTGCCC CGAGATGCGC GCCAGGGTCG CCATGCACCT CGTGTGCCCC 
TCGCGCTATG AGGCTGCTGT GCCCGACCCC CGAGAACCTG GAGAGTTTGC CCTGCTGCGG 
TCCTGCCAAG AGGTCTTTGA CAAGCTAGCC AGGGTGGCCC AGCCCGGGAT TAATTATGCA 
CTAGGGACCA ACACCTCCTA TCCCAATAAC CTGTTAAGGA ATCTGGCTCG GGAAGAGGCC 
AACTACGCCC TGGTGATTGA TGTGGACATG GTGCCCAGCG AAGGGCTGTG GAGAGGCCTG 
AGGGAAATGT TGGATCAGAG CAATCACTGG GATGGCACAG CCCTGGTGGT GCCTGCATTT 
GAAATCCGCC GGTCCCGCCG AATGCCGATG AACAAGAACG AGCTGGTGCA GCTCTATCAG 
GTGGGCGAAG TCCGGCCCTT CTATTATGGG CTGTGCACGC CTTGCCATGC GCCCACCAAC 
TACTCCCGCT GGGTCAACCT GCCAGAGGAG AGCTTGCTGA GACCTGCCTA CGTGGTGCCC 
TGGAGGGACC CCTGGGAACC ATTTTATGTG GCTGGAGGAA AGGTGCCCAC ATTTGACGAA 
CGCTTTCGGC AGTATGGTTT CAATCGAATC AGCCAGGCTT GTGAGCTGCA CGTGGCAGGG 
TTTAATTTTG AGGTGCTGAA CGAAGGTTTT CTGGTTCATA AGGGATTCAA GGAGGCATTG 
AAGTTCCATC CCCAAAAGGA GGCTGAAAAC CAGCGCAATA AGATCCTTTA CCGCCAGTTC 
AAACAGGAGT TGAAGGCTAG GTACCCCAAC TCTCCCCACC GATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780592.1
CDS	152..1399
Translation	MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRSVDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPNDVILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPEMRARVAMHLVCPSRYEAAVPDPREPGEFALLRSCQEVFDKLARVAQPGINYALGTNTSYPNNLLRNLAREEANYALVIDVDMVPSEGLWRGLREMLDQSNHWDGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEESLLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC

Target ORF information:

RefSeq Version	NM_175383.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus beta-1,4-glucuronyltransferase 1 (B4gat1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175383.2

ORF Insert Sequence:

ATGCAAATGT CCTACGCCAT CCGATGCGCC TTCTACCAGC TGCTGCTGGC CGCGCTCATG 
TTGGTGGCAA TGCTGCAGCT GCTCTACCTA TCGCTGCTCT CTGGACTGCA CGGCCAGGAG 
GAGCAGGAAC AGTATTTCGA GTTCTTCCCG CCGTCTCCGC GATCCGTAGA CCAGGTAAAG 
TCTCAACTCC GCACCGCACT GGCCTCCGGA GGCGTTCTAG ATGCCAGCGG CGATTATCGC 
GTCTACAGGG GTCTATTGAA GACCACCATG GACCCCAACG ATGTCATCTT AGCTACGCAT 
GCCAGTGTGG ACAACCTACT ACACCTGTCC GGACTTCTGG AGCGCTGGGA GGGTCCGCTG 
TCCGTTTCAG TGTTCGCGGC CACCAAAGAG GAGGCGCAGC TGGCCACGGT GCTGGCCTAC 
GCGCTGAGTA GCCACTGCCC CGAGATGCGC GCCAGGGTCG CCATGCACCT CGTGTGCCCC 
TCGCGCTATG AGGCTGCTGT GCCCGACCCC CGAGAACCTG GAGAGTTTGC CCTGCTGCGG 
TCCTGCCAAG AGGTCTTTGA CAAGCTAGCC AGGGTGGCCC AGCCCGGGAT TAATTATGCA 
CTAGGGACCA ACACCTCCTA TCCCAATAAC CTGTTAAGGA ATCTGGCTCG GGAAGAGGCC 
AACTACGCCC TGGTGATTGA TGTGGACATG GTGCCCAGCG AAGGGCTGTG GAGAGGCCTG 
AGGGAAATGT TGGATCAGAG CAATCACTGG GATGGCACAG CCCTGGTGGT GCCTGCATTT 
GAAATCCGCC GGTCCCGCCG AATGCCGATG AACAAGAACG AGCTGGTGCA GCTCTATCAG 
GTGGGCGAAG TCCGGCCCTT CTATTATGGG CTGTGCACGC CTTGCCATGC GCCCACCAAC 
TACTCCCGCT GGGTCAACCT GCCAGAGGAG AGCTTGCTGA GACCTGCCTA CGTGGTGCCC 
TGGAGGGACC CCTGGGAACC ATTTTATGTG GCTGGAGGAA AGGTGCCCAC ATTTGACGAA 
CGCTTTCGGC AGTATGGTTT CAATCGAATC AGCCAGGCTT GTGAGCTGCA CGTGGCAGGG 
TTTAATTTTG AGGTGCTGAA CGAAGGTTTT CTGGTTCATA AGGGATTCAA GGAGGCATTG 
AAGTTCCATC CCCAAAAGGA GGCTGAAAAC CAGCGCAATA AGATCCTTTA CCGCCAGTTC 
AAACAGGAGT TGAAGGCTAG GTACCCCAAC TCTCCCCACC GATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation.
eLife3(2014 Oct)
Willer T,Inamori K,Venzke D,Harvey C,Morgensen G,Hara Y,Beltrán Valero de Bernabé D,Yu L,Wright KM,Campbell KP

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.
Scientific reports33288(2013 Nov)
Yagi H,Nakagawa N,Saito T,Kiyonari H,Abe T,Toda T,Wu SW,Khoo KH,Oka S,Kato K

Dystroglycan organizes axon guidance cue localization and axonal pathfinding.
Neuron76(5)931-44(2012 Dec)
Wright KM,Lyon KA,Leung H,Leahy DJ,Ma L,Ginty DD

Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.
The American journal of pathology178(1)423-33(2011 Jan)
Arata-Kawai H,Singer MS,Bistrup A,Zante Av,Wang YQ,Ito Y,Bao X,Hemmerich S,Fukuda M,Rosen SD

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B4gat1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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