TNS1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	TNS1
Entrez Gene ID	396439
Full Name	tensin 1
Synonyms	TNS
General protein information	Preferred Names tensin 1 Names tensin
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205455.1	NP_990786.1	tensin

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC696960	XP_002808070.1
Bos taurus (cattle)	TNS1	NP_777191.1
Danio rerio (zebrafish)	tns1	XP_003199292.2
Xenopus tropicalis (tropical clawed frog)	tns1	XP_004918285.1
Homo sapiens (human)	TNS1	NP_072174.3
Pan troglodytes (chimpanzee)	TNS1	XP_516080.3
Mus musculus (house mouse)	Tns1	NP_082160.3
Canis lupus familiaris (dog)	TNS1	XP_005640681.1
Gallus gallus (chicken)	TNS1	NP_990786.1
Rattus norvegicus (Norway rat)	Tns1	NP_001178739.1

Gene Ontology
Bibliography

Related articles in PubMed

The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.
Qian X, Li G, Vass WC, Papageorge A, Walker RC, Asnaghi L, Steinbach PJ, Tosato G, Hunter K, Lowy DR
Cancer cell16(3)246-58(2009 Sep)

Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
Qian X, Li G, Asmussen HK, Asnaghi L, Vass WC, Braverman R, Yamada KM, Popescu NC, Papageorge AG, Lowy DR
Proceedings of the National Academy of Sciences of the United States of America104(21)9012-7(2007 May)

Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin.
Chuang JZ, Lin DC, Lin S
The Journal of cell biology128(6)1095-109(1995 Mar)

Molecular cloning of chick cardiac muscle tensin. Full-length cDNA sequence, expression, and characterization.
Lo SH, An Q, Bao S, Wong WK, Liu Y, Janmey PA, Hartwig JH, Chen LB
The Journal of biological chemistry269(35)22310-9(1994 Sep)

Modulation of tensin and vimentin expression in chick embryo developing cartilage and cultured differentiating chondrocytes.
van de Werken R, Gennari M, Tavella S, Bet P, Molina F, Lin S, Cancedda R, Castagnola P
European journal of biochemistry217(2)781-90(1993 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TNS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26924	NM_205455.1 Latest version!	Gallus gallus tensin 1 (TNS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TNS1 ( NM_205455.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990786.1 Gallus gallus tensin 1 (TNS1), mRNA.

Price & Availability↑

CloneID	OGa26924
Clone ID Related Accession (Same CDS sequence)	NM_205455.1
Accession Version	NM_205455.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1547740800000
Organism	Gallus gallus(chicken)
Product	tensin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M74165.1. ##Evidence-Data-START## CDS exon combination :: M74165.1 [ECO:0000331] ##Evidence-Data-END##

ATGGATTTCG GAAGCGTCAT GAACCAGGCT GCCACCCCGT GCTCCCCTGC TGTCAACTAT 
GAGCTGCCAT CCCCAGGGCA GAGCATCACC AAGCAGGTGG ACACCCCGGA CGCCACGAGG 
TCCCCCAGAG GTGGGCAGGC ACACTGCAAA GCATCCAGGA GCATGAGTGT GACAGCAGCC 
ATGGAGAGCA GCTGCGAGCT GGACCTGGTG TACATCACGG AGCGCATCAT CGCCGTCTCC 
TACCCCAGCA CAGCCGAGGA GCCAAGGAGC TTCCGCAGCA ACCTCCGTGA GGTGGCCCAC 
ATGCTGAAAT CCAAGCACGG GGACAACTAC GTGCTTTTCA ATCTGTCGGA ACGGAGACAT 
GATATCAGCA AACTTCACCC CAAGGTGCTG GATTTTGGGT GGCCTGACCT GCATACACCG 
GCACTGGAGA AGATCTGCAG CATTTGCAAA GCGATGGACA CGTGGCTGAA CGCGGCGGCT 
CACAACGTGG TGGTGCTGCA CAACAAGGGG AACCGTGGCC GCCTGGGGGT AGTCGTGGCT 
GCCTACATGC ACTACAGCAA TATCTCAGCC AGTGCTGACC AGGCTCTGGA CAGGTTTGCC 
ATGAAGCGCT TCTATGAGGA CAAAGTGGTG CCGGTGGGAC AGCCCTCCCA GAAGAGGTAC 
ATCCACTACT TCAGCGGGCT CCTGTCCGGC AGCATCAAGA TGAACAACAA GCCCCTCTTT 
CTGCACCACG TCATCATGCA TGGCATCCCC AACTTTGAAT CGAAAGGCGG TTGTCGGCCC 
TTCCTGAAGA TCTATCAGGC CATGCAGCCC GTCTACACAT CGGGGATCTA CAACGTGCAG 
GGGGACAGCC AGACGGGCAT CTGCATCACC ATCGAGCCCG GGCTGCTGCT CAAAGGCGAT 
ATCTTGCTCA AGTGCTACCA CAAGAAGTTC CGCAGCCCGA CCCGTGATGT GATTTTCCGT 
GTGCAGTTCC ACACTTGCGC TGTGCACGAC TTGGACATCG TCTTTGGCAA GGAGGACCTG 
GATGAGGCAT TCAGAGATGA ACGCTTCCCT GAATATGGAA AGGTGGAGTT CGTGTTCTCC 
TATGGCCCTG AGAAGATCCA AGGCATGGAG CACCTGGAGA ACGGCCCCAG CGTCTCAGTG 
GACTACAACA CATCCGACCC ACTCATCCGC TGGGACTCCT ACGAGAACTT CAACATCCAG 
CGTGAGGACA GCGCCGAGGG GACCTGGGCT GAGCCAGCAC TGCCGGGGAA GCACCTGGAA 
AAAGAGGTTG GGCACACGCA AGGGCCCCTG GACGGGAGCC TCTACGCTAA AGTGAAGAAG 
AAAGACTCCC TGCACGGCAG CATCGGCGCT GTCAACACCG CCCGCCTCCC CCTCTCGGCA 
GCCCCCAACC ACGTGGAGCA CACACTGTCG GTGAGCAGCG ACTCGGGCAA CTCCACCGCC 
TCCACCAAGA CCGACCGGAC GGATGAGCCG GGGGCTCCCG GAGCACCCAC TGGCCACGCG 
GTGCTGAGCC CCGAGGAGAA GCGGGACGTG GACCGTCTCC TGGTCGGCTT CGGCTTGGAG 
AGCGCGGCGC CCATGCACAA CCACGCGCCG GGCCCCGCAC CTGCCCGCCT GCCCGCCGGG 
CCGGGCCGCC ACGTGGTGCC GGCACAGGTG CACGTCAATG GTGCTGGCAC CCCACTGCTG 
GCTGAGCGGG AGACGGACAT CTTGGATGAT GAACTGCCCA ACCAGGATGG GCACAGCGTG 
GGCAGCCTGG GCACGCTCTC GTCCTTGGAT GGCACCACCA CTGCCAGTGA GGCTGGCTTC 
CACGAGGCGC CACGGGTGGG CAGCCTCTCC TCGCTGCCCA ACGGCCCGGC TAGCTACAAC 
GGGGCTGAGA AGATGCTGAA GGAAGGGCTT TATGAGGCTG AGCCTCTCTC CAACGGTGCC 
TACCCCTACA GCAACCAGAA TACCCTGATG GGCCACCACC TCCGTGACCC GCTGGCTCAC 
TTACGGCCCT CGCGATCCGC ACAGGAGCAC CTGGCCGGAT ACCCGCAGCG GCAGCCAGCT 
TCAGCTTCAC CGGCCTGGCT CCAGCCCCCA GTGCCACAGC CCTACCTGTA CGGTTATGAC 
CTACCCAGTG CCCACCGCTC ACAGTCCTTC CCGGCCGTGG GGACGGCCAA GTACGAAGCA 
AACCTGGCAT TACCGCAGGC TCCGGCTCGC AGCACCAGCA GCCGCGAGGC CGTGCAGCGG 
GGCCTGAATT CCTGGCAGCA GCAGGGCGGC AGCCGACCGC CATCCCAGCT GCATGATGGC 
GGCTTGGAGA GCCACAGCCC CAGCTTGTCC AGCTGCAGCC CCCAGCCCAG CCCGCTGCAG 
CCCATGCCCC CGCACAGCCA CAGCATGCCC GAGTTCCCCA GGGCTCCATC GCGCCGGGAG 
ATCGAGCAGT CCATTGAAGC ACTTGATGTC CTCATGCTGG ACCTTGCACC CTCCGTCCAT 
AAGTCTCAGA GTGTCCCCTC TGCAGCCACC CGCCAGGACA AGCCGGCTGC CATGCTCTCC 
TCGCTGTCGG CACAGCGCCT CAGCGGTCAC TATGCTCAGC CAACCCCACA AGTGGTCCAG 
CCCAGGTCCT TTGGCACCTC TGTGGGCACT GATCCCTTGG CCAAACCCTA CTCTCCTGGT 
CCACTGGTTC CTGCGGCTCG AAGTACTGCA GAGCCAGACT ACACCGTGCA TGAGTACCGG 
GAAACCTATA CTCCCTATAG CTACCAGCCA GTGCCAGAGC CTCGGAGCTA TGGCAGTGCA 
CCAGCGAGCA TCCTCCCCCT CAGCGCCTCG TACAGCCCCG CAGGGTCTCA GCAGCTTCTC 
GTCTCCTCCC CGCCATCCCC CACTGCGCCA GCACAAAGCC AGCTGCCCCA CAAGGGACTG 
GAGAGCTATG AAGACCTGTC GAGATCGGGA GAAGAGCCTT TGAATCTGGA AGGGCTGGTG 
GCCCACAGGG TGGCAGGGGT GCAGTCCCGG GAGAAGTCCC CAGAAGAGAG CACCGTCCCT 
GCCCGAAGGC GAACCCCCAG CGACAGCCAC TATGAGAAGA GCTCACCGGA GCCCGGTTCT 
CCCCGCAGCC CCACCGTCCT CTCGCCCGAG GTGGTCAGCA CCATCGCGGC CAACCCTGGA 
GGGAGGCCCA AAGAGCCTCA CCTCCACAGC TACAAGGAAG CCTTCGAGGA GATGGAGAGT 
GCCTCCCCCA GCAGCCTGAC CTCCGGCGGC GTGCGCTCTC CACCTGGCCT GGCCAAGACC 
CCTCTCTCAG CACTGGGGCT GAAACCCCAT AACCCAGCTG ACATCCTGCT GCACCCAGTG 
GGAGAGCCCA GGAGCTATGT TGAGTCAGTG GCCAGGACAG CCACGACTGG CAGGGCAGGG 
AACCTTCCAG CTGCCCAGCC TGTGGGCCTG GAGGTACCTG CCAGGAATGG TGCCTTTGGC 
AACTCCTTCA CTGTGCCCAG CCCCGTCTCT ACCAGCAGCC CCATCCACAG CGTGGACGGT 
GCCTCGCTCC GCAGCTACCC ATCGGAGGGC AGCCCCCACG GCACGGTTAC ACCTCCCCAC 
GCTGTAGCTG AGACAGCTTA CCGGTCACCC ATGGTCTCAC AGACGCCCTC TGCTCACAGC 
AGCTACCAAA CCTCGTCTCC ATCATCCTTC CAAGCGGGAA CACTGGGCTC TCCCTATGCC 
AGCCCTGACT ACCCTGACGG CCGAGGCGGC TTCCAGCCGG ACCCCCAGGC TCGGCAGCAG 
CCACAGGTCA GTGTGGTGGG TGTCCACGCG CTGCCAGGGA GCCCCCGCAC CCTGCACCGG 
ACAGTGGCGA CCAACACGCC GCCCAGCCCT GGCTTTGGGC GAAGAGCTGC CAACCCCGCT 
GTTGCCAGCG TGCCTGGCAG CCCTGGCCTG GGCCGGCACA CCGTGTCCCC CCACGCGCCA 
CCGGGGAGCC CCAGCCTTGC CCGGCATCAG ATGGCAGCCG TGCCTCCCGG CAGCCCCATG 
TACGGCTACT CCAGCCCGGA AGAGAGGCGC CCGACGCTGT CCCGGCAGAG CAGCGCGTCC 
GGCTACCAGC CTCCCTCCAC GCCGTCCTTC CCCGTCTCAC CGGCGTACTA TCCCGGCACC 
AGCACGCCGC ACTCCTCCTC CCCGGACTCC GCCGCCTACC GCCAGGGCAG CCCCACTCCG 
CAGCCCGCGC TGCCTGAGAA GAGGCGGATG TCAGCCGGTG AGCGCTCCAA CAGCCTGCCC 
AACTATGCCA CGGTCAACGG CAAGGCCTCC TCGCCCCTCT CCAGTGGCAT GTCCAGCCCC 
AGCAGCGGCA GCGCTGTGGC TTTCTCCCAC ACCCTGCCGG ATTTCTCCAA GTTTTCCATG 
CCAGACATCA GCCCCGAGAC TCGCGCCAAC GTGAAGTTTG TGCAGGACAC TTCCAAGTAC 
TGGTACAAGC CAGACATCTC CCGGGAGCAA GCCATCGCGC TGCTGAAGGA CAGGGAGCCA 
GGGGCTTTCA TCATCCGGGA CAGCCACTCC TTCCGGGGAG CCTATGGCCT TGCCATGAAA 
GTCGCTTCCC CACCTCCCAC CGTCATGCAG CAGAACAAGA AAGGAGACAT TACCAATGAA 
CTGGTGAGGC ACTTCCTCAT CGAGACCAGC CCACGGGGTG TGAAACTAAA AGGATGCCCC 
AATGAGCCTA ATTTTGGCTG CTTGTCGGCT CTGGTCTACC AGCACTCCAT CATGCCTCTG 
GCCCTGCCCT GCAAGCTGGT CATTCCTGAC CGAGATCCCA TGGAGGAGAA GAAAGATGCT 
GCGTCGACCA CCAACTCAGC CACAGACCTT CTCAAACAGG GTGCGGCCTG CAATGTCCTT 
TTCATCAATT CAGTGGAGAT GGAATCGCTC ACAGGCCCGC AGGCCATCTC CAAGGCTGTG 
GCAGAGACAT TGGTGGCTGA TCCCACGCCG ACCGCTACGA TCGTCCACTT CAAAGTCTCT 
GCACAGGGCA TCACCTTAAC AGACAACCAG AGGAAACTGT TCTTCCGACG ACACTATCCT 
CTCAATACTG TCACCTTCTG TGATTTGGAC CCCCAGGAAC GAAAGTGGAC TAAAACTGAC 
GGCAGTGGCC CAGCCAAGCT CTTCGGCTTC GTGGCCAGGA AGCAAGGGAG CACCACGGAC 
AACGTCTGCC ACCTCTTTGC AGAGCTGGAC CCTGACCAGC CGGCTGCGGC CATCGTCAAC 
TTTGTCTCCA GGGTCATGCT TGGATCCGGC CAGAAGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990786.1
CDS	965..6166
Translation	MDFGSVMNQAATPCSPAVNYELPSPGQSITKQVDTPDATRSPRGGQAHCKASRSMSVTAAMESSCELDLVYITERIIAVSYPSTAEEPRSFRSNLREVAHMLKSKHGDNYVLFNLSERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRLGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGLLLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSAEGTWAEPALPGKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNTARLPLSAAPNHVEHTLSVSSDSGNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRDVDRLLVGFGLESAAPMHNHAPGPAPARLPAGPGRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLDGTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSNGAYPYSNQNTLMGHHLRDPLAHLRPSRSAQEHLAGYPQRQPASASPAWLQPPVPQPYLYGYDLPSAHRSQSFPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLESHSPSLSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPSVHKSQSVPSAATRQDKPAAMLSSLSAQRLSGHYAQPTPQVVQPRSFGTSVGTDPLAKPYSPGPLVPAARSTAEPDYTVHEYRETYTPYSYQPVPEPRSYGSAPASILPLSASYSPAGSQQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRSGEEPLNLEGLVAHRVAGVQSREKSPEESTVPARRRTPSDSHYEKSSPEPGSPRSPTVLSPEVVSTIAANPGGRPKEPHLHSYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVGEPRSYVESVARTATTGRAGNLPAAQPVGLEVPARNGAFGNSFTVPSPVSTSSPIHSVDGASLRSYPSEGSPHGTVTPPHAVAETAYRSPMVSQTPSAHSSYQTSSPSSFQAGTLGSPYASPDYPDGRGGFQPDPQARQQPQVSVVGVHALPGSPRTLHRTVATNTPPSPGFGRRAANPAVASVPGSPGLGRHTVSPHAPPGSPSLARHQMAAVPPGSPMYGYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYPGTSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGMSSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLKDREPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLKGCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAACNVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAAAIVNFVSRVMLGSGQKR

Target ORF information:

RefSeq Version	NM_205455.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus tensin 1 (TNS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205455.1

ORF Insert Sequence:

ATGGATTTCG GAAGCGTCAT GAACCAGGCT GCCACCCCGT GCTCCCCTGC TGTCAACTAT 
GAGCTGCCAT CCCCAGGGCA GAGCATCACC AAGCAGGTGG ACACCCCGGA CGCCACGAGG 
TCCCCCAGAG GTGGGCAGGC ACACTGCAAA GCATCCAGGA GCATGAGTGT GACAGCAGCC 
ATGGAGAGCA GCTGCGAGCT GGACCTGGTG TACATCACGG AGCGCATCAT CGCCGTCTCC 
TACCCCAGCA CAGCCGAGGA GCCAAGGAGC TTCCGCAGCA ACCTCCGTGA GGTGGCCCAC 
ATGCTGAAAT CCAAGCACGG GGACAACTAC GTGCTTTTCA ATCTGTCGGA ACGGAGACAT 
GATATCAGCA AACTTCACCC CAAGGTGCTG GATTTTGGGT GGCCTGACCT GCATACACCG 
GCACTGGAGA AGATCTGCAG CATTTGCAAA GCGATGGACA CGTGGCTGAA CGCGGCGGCT 
CACAACGTGG TGGTGCTGCA CAACAAGGGG AACCGTGGCC GCCTGGGGGT AGTCGTGGCT 
GCCTACATGC ACTACAGCAA TATCTCAGCC AGTGCTGACC AGGCTCTGGA CAGGTTTGCC 
ATGAAGCGCT TCTATGAGGA CAAAGTGGTG CCGGTGGGAC AGCCCTCCCA GAAGAGGTAC 
ATCCACTACT TCAGCGGGCT CCTGTCCGGC AGCATCAAGA TGAACAACAA GCCCCTCTTT 
CTGCACCACG TCATCATGCA TGGCATCCCC AACTTTGAAT CGAAAGGCGG TTGTCGGCCC 
TTCCTGAAGA TCTATCAGGC CATGCAGCCC GTCTACACAT CGGGGATCTA CAACGTGCAG 
GGGGACAGCC AGACGGGCAT CTGCATCACC ATCGAGCCCG GGCTGCTGCT CAAAGGCGAT 
ATCTTGCTCA AGTGCTACCA CAAGAAGTTC CGCAGCCCGA CCCGTGATGT GATTTTCCGT 
GTGCAGTTCC ACACTTGCGC TGTGCACGAC TTGGACATCG TCTTTGGCAA GGAGGACCTG 
GATGAGGCAT TCAGAGATGA ACGCTTCCCT GAATATGGAA AGGTGGAGTT CGTGTTCTCC 
TATGGCCCTG AGAAGATCCA AGGCATGGAG CACCTGGAGA ACGGCCCCAG CGTCTCAGTG 
GACTACAACA CATCCGACCC ACTCATCCGC TGGGACTCCT ACGAGAACTT CAACATCCAG 
CGTGAGGACA GCGCCGAGGG GACCTGGGCT GAGCCAGCAC TGCCGGGGAA GCACCTGGAA 
AAAGAGGTTG GGCACACGCA AGGGCCCCTG GACGGGAGCC TCTACGCTAA AGTGAAGAAG 
AAAGACTCCC TGCACGGCAG CATCGGCGCT GTCAACACCG CCCGCCTCCC CCTCTCGGCA 
GCCCCCAACC ACGTGGAGCA CACACTGTCG GTGAGCAGCG ACTCGGGCAA CTCCACCGCC 
TCCACCAAGA CCGACCGGAC GGATGAGCCG GGGGCTCCCG GAGCACCCAC TGGCCACGCG 
GTGCTGAGCC CCGAGGAGAA GCGGGACGTG GACCGTCTCC TGGTCGGCTT CGGCTTGGAG 
AGCGCGGCGC CCATGCACAA CCACGCGCCG GGCCCCGCAC CTGCCCGCCT GCCCGCCGGG 
CCGGGCCGCC ACGTGGTGCC GGCACAGGTG CACGTCAATG GTGCTGGCAC CCCACTGCTG 
GCTGAGCGGG AGACGGACAT CTTGGATGAT GAACTGCCCA ACCAGGATGG GCACAGCGTG 
GGCAGCCTGG GCACGCTCTC GTCCTTGGAT GGCACCACCA CTGCCAGTGA GGCTGGCTTC 
CACGAGGCGC CACGGGTGGG CAGCCTCTCC TCGCTGCCCA ACGGCCCGGC TAGCTACAAC 
GGGGCTGAGA AGATGCTGAA GGAAGGGCTT TATGAGGCTG AGCCTCTCTC CAACGGTGCC 
TACCCCTACA GCAACCAGAA TACCCTGATG GGCCACCACC TCCGTGACCC GCTGGCTCAC 
TTACGGCCCT CGCGATCCGC ACAGGAGCAC CTGGCCGGAT ACCCGCAGCG GCAGCCAGCT 
TCAGCTTCAC CGGCCTGGCT CCAGCCCCCA GTGCCACAGC CCTACCTGTA CGGTTATGAC 
CTACCCAGTG CCCACCGCTC ACAGTCCTTC CCGGCCGTGG GGACGGCCAA GTACGAAGCA 
AACCTGGCAT TACCGCAGGC TCCGGCTCGC AGCACCAGCA GCCGCGAGGC CGTGCAGCGG 
GGCCTGAATT CCTGGCAGCA GCAGGGCGGC AGCCGACCGC CATCCCAGCT GCATGATGGC 
GGCTTGGAGA GCCACAGCCC CAGCTTGTCC AGCTGCAGCC CCCAGCCCAG CCCGCTGCAG 
CCCATGCCCC CGCACAGCCA CAGCATGCCC GAGTTCCCCA GGGCTCCATC GCGCCGGGAG 
ATCGAGCAGT CCATTGAAGC ACTTGATGTC CTCATGCTGG ACCTTGCACC CTCCGTCCAT 
AAGTCTCAGA GTGTCCCCTC TGCAGCCACC CGCCAGGACA AGCCGGCTGC CATGCTCTCC 
TCGCTGTCGG CACAGCGCCT CAGCGGTCAC TATGCTCAGC CAACCCCACA AGTGGTCCAG 
CCCAGGTCCT TTGGCACCTC TGTGGGCACT GATCCCTTGG CCAAACCCTA CTCTCCTGGT 
CCACTGGTTC CTGCGGCTCG AAGTACTGCA GAGCCAGACT ACACCGTGCA TGAGTACCGG 
GAAACCTATA CTCCCTATAG CTACCAGCCA GTGCCAGAGC CTCGGAGCTA TGGCAGTGCA 
CCAGCGAGCA TCCTCCCCCT CAGCGCCTCG TACAGCCCCG CAGGGTCTCA GCAGCTTCTC 
GTCTCCTCCC CGCCATCCCC CACTGCGCCA GCACAAAGCC AGCTGCCCCA CAAGGGACTG 
GAGAGCTATG AAGACCTGTC GAGATCGGGA GAAGAGCCTT TGAATCTGGA AGGGCTGGTG 
GCCCACAGGG TGGCAGGGGT GCAGTCCCGG GAGAAGTCCC CAGAAGAGAG CACCGTCCCT 
GCCCGAAGGC GAACCCCCAG CGACAGCCAC TATGAGAAGA GCTCACCGGA GCCCGGTTCT 
CCCCGCAGCC CCACCGTCCT CTCGCCCGAG GTGGTCAGCA CCATCGCGGC CAACCCTGGA 
GGGAGGCCCA AAGAGCCTCA CCTCCACAGC TACAAGGAAG CCTTCGAGGA GATGGAGAGT 
GCCTCCCCCA GCAGCCTGAC CTCCGGCGGC GTGCGCTCTC CACCTGGCCT GGCCAAGACC 
CCTCTCTCAG CACTGGGGCT GAAACCCCAT AACCCAGCTG ACATCCTGCT GCACCCAGTG 
GGAGAGCCCA GGAGCTATGT TGAGTCAGTG GCCAGGACAG CCACGACTGG CAGGGCAGGG 
AACCTTCCAG CTGCCCAGCC TGTGGGCCTG GAGGTACCTG CCAGGAATGG TGCCTTTGGC 
AACTCCTTCA CTGTGCCCAG CCCCGTCTCT ACCAGCAGCC CCATCCACAG CGTGGACGGT 
GCCTCGCTCC GCAGCTACCC ATCGGAGGGC AGCCCCCACG GCACGGTTAC ACCTCCCCAC 
GCTGTAGCTG AGACAGCTTA CCGGTCACCC ATGGTCTCAC AGACGCCCTC TGCTCACAGC 
AGCTACCAAA CCTCGTCTCC ATCATCCTTC CAAGCGGGAA CACTGGGCTC TCCCTATGCC 
AGCCCTGACT ACCCTGACGG CCGAGGCGGC TTCCAGCCGG ACCCCCAGGC TCGGCAGCAG 
CCACAGGTCA GTGTGGTGGG TGTCCACGCG CTGCCAGGGA GCCCCCGCAC CCTGCACCGG 
ACAGTGGCGA CCAACACGCC GCCCAGCCCT GGCTTTGGGC GAAGAGCTGC CAACCCCGCT 
GTTGCCAGCG TGCCTGGCAG CCCTGGCCTG GGCCGGCACA CCGTGTCCCC CCACGCGCCA 
CCGGGGAGCC CCAGCCTTGC CCGGCATCAG ATGGCAGCCG TGCCTCCCGG CAGCCCCATG 
TACGGCTACT CCAGCCCGGA AGAGAGGCGC CCGACGCTGT CCCGGCAGAG CAGCGCGTCC 
GGCTACCAGC CTCCCTCCAC GCCGTCCTTC CCCGTCTCAC CGGCGTACTA TCCCGGCACC 
AGCACGCCGC ACTCCTCCTC CCCGGACTCC GCCGCCTACC GCCAGGGCAG CCCCACTCCG 
CAGCCCGCGC TGCCTGAGAA GAGGCGGATG TCAGCCGGTG AGCGCTCCAA CAGCCTGCCC 
AACTATGCCA CGGTCAACGG CAAGGCCTCC TCGCCCCTCT CCAGTGGCAT GTCCAGCCCC 
AGCAGCGGCA GCGCTGTGGC TTTCTCCCAC ACCCTGCCGG ATTTCTCCAA GTTTTCCATG 
CCAGACATCA GCCCCGAGAC TCGCGCCAAC GTGAAGTTTG TGCAGGACAC TTCCAAGTAC 
TGGTACAAGC CAGACATCTC CCGGGAGCAA GCCATCGCGC TGCTGAAGGA CAGGGAGCCA 
GGGGCTTTCA TCATCCGGGA CAGCCACTCC TTCCGGGGAG CCTATGGCCT TGCCATGAAA 
GTCGCTTCCC CACCTCCCAC CGTCATGCAG CAGAACAAGA AAGGAGACAT TACCAATGAA 
CTGGTGAGGC ACTTCCTCAT CGAGACCAGC CCACGGGGTG TGAAACTAAA AGGATGCCCC 
AATGAGCCTA ATTTTGGCTG CTTGTCGGCT CTGGTCTACC AGCACTCCAT CATGCCTCTG 
GCCCTGCCCT GCAAGCTGGT CATTCCTGAC CGAGATCCCA TGGAGGAGAA GAAAGATGCT 
GCGTCGACCA CCAACTCAGC CACAGACCTT CTCAAACAGG GTGCGGCCTG CAATGTCCTT 
TTCATCAATT CAGTGGAGAT GGAATCGCTC ACAGGCCCGC AGGCCATCTC CAAGGCTGTG 
GCAGAGACAT TGGTGGCTGA TCCCACGCCG ACCGCTACGA TCGTCCACTT CAAAGTCTCT 
GCACAGGGCA TCACCTTAAC AGACAACCAG AGGAAACTGT TCTTCCGACG ACACTATCCT 
CTCAATACTG TCACCTTCTG TGATTTGGAC CCCCAGGAAC GAAAGTGGAC TAAAACTGAC 
GGCAGTGGCC CAGCCAAGCT CTTCGGCTTC GTGGCCAGGA AGCAAGGGAG CACCACGGAC 
AACGTCTGCC ACCTCTTTGC AGAGCTGGAC CCTGACCAGC CGGCTGCGGC CATCGTCAAC 
TTTGTCTCCA GGGTCATGCT TGGATCCGGC CAGAAGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.
Cancer cell16(3)246-58(2009 Sep)
Qian X,Li G,Vass WC,Papageorge A,Walker RC,Asnaghi L,Steinbach PJ,Tosato G,Hunter K,Lowy DR

Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
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