| Gene Symbol | ctns |
| Entrez Gene ID | 553594 |
| Full Name | cystinosin, lysosomal cystine transporter |
| Synonyms | zgc:110194 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Danio rerio(zebrafish) |
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ctns cDNA ORF clone, Danio rerio(zebrafish)
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Gene
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Clones
gRNAs
The following ctns gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ctns cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ODa02864 Clone ID Related Accession (Same CDS sequence) NM_001020571.1 Accession Version NM_001020571.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1155bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1545408000000 Organism Danio rerio(zebrafish) Product cystinosin precursor Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095197.1. ##Evidence-Data-START## Transcript exon combination :: BC095197.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141ATGTTGAAGC AGACTTTCTT TTTGTTTCTT TTAACTCTGT ATCTCTGTAA ACACACAGCA
TTTGGTGATC CAGAAGTGGC CGTCAGTGCT CCCGCAACAG TGAATCTACA GGAATTTTCT
TCAGAAAACA TCACCATTAC ACTGAGTTCA CCGCTGAACA CATCTGTAAC GGTTTATTTC
AATATCACTT ATGAATCAAA TAATGTGTCT TTAATAATTC AACTACCCGA TGAGGTTGTT
GTACCAGCTG GAAACACATC TGTATCTTTT GCAGTGCAGG CAAAAGGGGT TGGTCAGGTG
ACCGCGTACC TTAGCAGCAA TGACACTCAC ATAAAAAGTT TAGATGCACG GATCAGATTC
TTGATCGTCA GGAGCAATGC CCTTTTCATC ATCAACCAAA TCATCGGCTG GATTTACTTT
GTGGCCTGGT CTGTGTCGTT TTACCCACAG GCATACGAGA ACTGGAAGAG ACGCAGTGTG
GTTGGCCTTA ATTTTGATTT CCTCGCTCTC AACCTGACTG GATTCATCGC CTACAGTGTG
TTCAACGTTG GCCTTTTCTG GGTGACGTAT ATTCAGGAGG AATTCTTGAA GAAAGATCCA
AACGGAGTCA TTCCTGTGGA TGCCAACGAT GTGTTCTTCA GTCTCCATGC ATTACTTCTC
ACTCTGGTCT ATATCTGCCA GTGTGCCATC TATGAGAGAG GTGGGCAAAA GGTCTCCAAA
GTGGCCATTG GGTTATTAGC TATCGGCTGG ACCTTTGCAT TTGTCTCTCT GTTTGTGGCT
GTGGCAAAGA AAATCTCCTG GCTGGATTAT CTGTACTATT TCTCCTACAT TAAACTGGGT
GTCACACTAG TGAAATACAT CCCTCAGGCT CACATGAACT ACCGCAGGAA GAGCACAGAG
GGCTGGAGCA TCGGCAATGT GCTGCTGGAC TTCACAGGGG GCAGTTTCAG TTTGATCCAG
ATGTTCCTTG AGGCCTATAA CAATGATAAA TGGAGGTTTA TATTTGGAGA CCCTACTAAG
TTCGGACTGG GCATCTTTTC CATATTCTTT GACATTTTGT TCATCATACA GCATTATTGT
CTGTACAGGA ACCGAGAGCC GATGTATCAG GATTTAGATG AACAAAATGA TCAACACAGC
AGTGTGAAAA CCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001018407.1 CDS 159..1313 Translation 
Target ORF information:
RefSeq Version NM_001020571.1 Organism Danio rerio(zebrafish) Definition Danio rerio cystinosin, lysosomal cystine transporter (ctns), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001020571.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141ATGTTGAAGC AGACTTTCTT TTTGTTTCTT TTAACTCTGT ATCTCTGTAA ACACACAGCA
TTTGGTGATC CAGAAGTGGC CGTCAGTGCT CCCGCAACAG TGAATCTACA GGAATTTTCT
TCAGAAAACA TCACCATTAC ACTGAGTTCA CCGCTGAACA CATCTGTAAC GGTTTATTTC
AATATCACTT ATGAATCAAA TAATGTGTCT TTAATAATTC AACTACCCGA TGAGGTTGTT
GTACCAGCTG GAAACACATC TGTATCTTTT GCAGTGCAGG CAAAAGGGGT TGGTCAGGTG
ACCGCGTACC TTAGCAGCAA TGACACTCAC ATAAAAAGTT TAGATGCACG GATCAGATTC
TTGATCGTCA GGAGCAATGC CCTTTTCATC ATCAACCAAA TCATCGGCTG GATTTACTTT
GTGGCCTGGT CTGTGTCGTT TTACCCACAG GCATACGAGA ACTGGAAGAG ACGCAGTGTG
GTTGGCCTTA ATTTTGATTT CCTCGCTCTC AACCTGACTG GATTCATCGC CTACAGTGTG
TTCAACGTTG GCCTTTTCTG GGTGACGTAT ATTCAGGAGG AATTCTTGAA GAAAGATCCA
AACGGAGTCA TTCCTGTGGA TGCCAACGAT GTGTTCTTCA GTCTCCATGC ATTACTTCTC
ACTCTGGTCT ATATCTGCCA GTGTGCCATC TATGAGAGAG GTGGGCAAAA GGTCTCCAAA
GTGGCCATTG GGTTATTAGC TATCGGCTGG ACCTTTGCAT TTGTCTCTCT GTTTGTGGCT
GTGGCAAAGA AAATCTCCTG GCTGGATTAT CTGTACTATT TCTCCTACAT TAAACTGGGT
GTCACACTAG TGAAATACAT CCCTCAGGCT CACATGAACT ACCGCAGGAA GAGCACAGAG
GGCTGGAGCA TCGGCAATGT GCTGCTGGAC TTCACAGGGG GCAGTTTCAG TTTGATCCAG
ATGTTCCTTG AGGCCTATAA CAATGATAAA TGGAGGTTTA TATTTGGAGA CCCTACTAAG
TTCGGACTGG GCATCTTTTC CATATTCTTT GACATTTTGT TCATCATACA GCATTATTGT
CTGTACAGGA ACCGAGAGCC GATGTATCAG GATTTAGATG AACAAAATGA TCAACACAGC
AGTGTGAAAA CCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney.
Nature communications9(1)161(2018 01)
Festa BP,Chen Z,Berquez M,Debaix H,Tokonami N,Prange JA,Hoek GV,Alessio C,Raimondi A,Nevo N,Giles RH,Devuyst O,Luciani A
Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.
Scientific reports742583(2017 02)
Elmonem MA,Khalil R,Khodaparast L,Khodaparast L,Arcolino FO,Morgan J,Pastore A,Tylzanowski P,Ny A,Lowe M,de Witte PA,Baelde HJ,van den Heuvel LP,Levtchenko E
RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R
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