ORF » Species Summary » Rattus norvegicus » Reactome

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Rattus norvegicus (Norway rat)

Browse by Letter Index, Genomic Locus


Gene Silencing by RNA Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
HuR (ELAVL1) binds and stabilizes mRNA Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
snRNP Assembly Epigenetic regulation of gene expression
PRC2 methylates histones and DNA TET1,2,3 and TDG demethylate DNA
Transcriptional activation of p53 responsive genes Transcriptional activation of cell cycle inhibitor p21
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex G2/M DNA replication checkpoint
Mitotic Spindle Checkpoint Inactivation of APC/C via direct inhibition of the APC/C complex
G0 and Early G1 G1 Phase
E2F-enabled inhibition of pre-replication complex formation Cyclin A:Cdk2-associated events at S phase entry
Ubiquitin-dependent degradation of Cyclin D1 Recruitment of mitotic centrosome proteins and complexes
Loss of Nlp from mitotic centrosomes Golgi Cisternae Pericentriolar Stack Reorganization
MASTL Facilitates Mitotic Progression Nuclear Envelope Breakdown
Clearance of Nuclear Envelope Membranes from Chromatin Resolution of Sister Chromatid Cohesion
Mitotic Metaphase and Anaphase Regulation of mitotic cell cycle
APC/C-mediated degradation of cell cycle proteins Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
APC/C:Cdc20 mediated degradation of Cyclin B Metabolism of lipids and lipoproteins
LDL-mediated lipid transport Import of palmitoyl-CoA into the mitochondrial matrix
mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Beta oxidation of octanoyl-CoA to hexanoyl-CoA Peroxisomal lipid metabolism
Beta-oxidation of pristanoyl-CoA Beta-oxidation of very long chain fatty acids
Bile acid and bile salt metabolism Synthesis of PC
Acyl chain remodelling of PC Hydrolysis of LPC
Synthesis of PS PI Metabolism
Glycerophospholipid catabolism Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Integration of energy metabolism Adrenaline,noradrenaline inhibits insulin secretion
Acetylcholine regulates insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
The citric acid (TCA) cycle and respiratory electron transport Pyruvate metabolism
Regulation of pyruvate dehydrogenase (PDH) complex Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Formation of ATP by chemiosmotic coupling Metabolism of nucleotides
Pyrimidine salvage reactions Pyrimidine catabolism
Vitamins B6 activation to pyridoxal phosphate Vitamin D (calciferol) metabolism
Serine biosynthesis Phenylalanine and tyrosine catabolism
Metabolism of polyamines Heme biosynthesis
Endogenous sterols Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
FMO oxidises nucleophiles Amine Oxidase reactions
Ethanol oxidation O2/CO2 exchange in erythrocytes
Negative regulation of activity of TFAP2 (AP-2) family transcription factors RET signaling
SMAC-mediated apoptotic response Deubiquitination
Ub-specific processing proteases APC/C:Cdc20 mediated degradation of Securin
Chromosome Maintenance Nucleosome assembly
Telomere Maintenance Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere Association of TriC/CCT with target proteins during biosynthesis
Gamma-carboxylation of protein precursors Synthesis of diphthamide-EEF2
Synthesis of Dolichyl-phosphate Synthesis of GDP-mannose
Sialic acid metabolism Calnexin/calreticulin cycle
N-glycan antennae elongation in the medial/trans-Golgi SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMOylation of DNA damage response and repair proteins SUMOylation of DNA replication proteins
Synthesis, secretion, and deacylation of Ghrelin Glycoprotein hormones
Unfolded Protein Response (UPR) Digestion of dietary carbohydrate
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