Advanced mRNA and LNP Strategies for CRISPR Delivery

Recent breakthroughs in RNA therapeutics have unveiled the incredible potential of mRNA-based tools for gene editing. Lipid nanoparticles (LNPs) can co-encapsulate mRNA and guide RNA for highly efficient delivery both to cells ^{in vitro} and ^{in vivo.}

GenScript’s cutting-edge platform produces top-quality mRNA with enhanced expression, reduced immunogenicity, and extended half-life. Paired with a novel guide RNA design, this guarantees exceptional editing efficiency with low off-target effects.

In this webinar, Dr. Shambhavi Shubham, field application scientist at GenScript will share how the company harnesses advanced formulations of CRISPR enzymes like Cas9 and Cas12, and Prime editing to achieve powerful gene editing. To further elevate performance, GenScript leverages advanced strategies, including customizing CRISPR mRNAs with tissue-specific UTRs, optimizing IVT conditions to reduce dsRNA, and using codon optimization and circular RNA forms. Moreover, to meet precise delivery needs, GenScript technology leverages antibody-decorated or SORT LNPs.

Join us and learn how GenScript’s advanced platform serves the needs of researchers and biopharmaceutical companies by driving the rapid development of ground-breaking therapeutics and propelling genetics research forward.

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Advanced mRNA and LNP Strategies for CRISPR Delivery

Advanced mRNA and LNP Strategies for CRISPR Delivery

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