GenSmart™ Design: Simplify Your Plasmid Design Work

FAQs

• 1. What is the difference between "GenSmart™ Design" and "GenSmart™ 2.0 Online Ordering"?

  GenSmart™ Design is our self-developed vector design tool enables users to easily create vector designs through simple component selection and sequence insertion. Completed designs can be ordered online, seamlessly connecting to our offline production process for final delivery.

  Key Differences With GenSmart™ 2.0 Online Ordering

  • Flexible Vector Design: Support adding/replacing multiple components to customize vectors.
  • Enhanced Visualization: Provide an intuitive interface with real-time vector map and sequence visualization, improving design clarity.
  • Advanced Vector Selection: Efficiently categorize vectors for diverse applications, enabling users to easily choose the most suitable option for their specific downstream needs.
• 2. What vectors can I choose when using the GenSmart™ Design tool?

  GenSmart™ Design offers a variety of vectors tailored for specific applications. You can select vector backbones from targeted modules designed for:

  • AAV (Adeno-Associated Virus)
  • LVV (Lentiviral Vectors)
  • mRNA(Coming Soon)
  • Antibody expression (Coming Soon)
  • Gene editing (Coming Soon)

  Each application area provides multiple vector types to address specific needs, such as expression regulation and gene editing, ensuring you find the right vector for your project.

• 3. How can I check if my design is correct?

  After completing your design, a "View ORF" button will appear in the top-right corner. You can click this button to check whether the actual ORF region matches your design, ensuring the accuracy of your vector design.

  If you need more professional design guidance, our technical support team is available to assist you at any time. Please click the chat box in the bottom right corner to seek help from them.

• 4. How to handle those difficult genes for which pricing information is unavailable?
  • Inquire for a Quote: If your customized sequence is complex and marked as "TBD" (To Be Determined) for pricing, you can request a quote on the 'Get Quote' page. Our technical support team will evaluate the sequence and provide you with a final price.
  • Codon Optimization: Use the codon optimization feature available on the design page. This tool can help simplify complex sequences by optimizing the codon usage, potentially making the sequence easier to synthesize and possibly affecting the pricing.
• 5. How to bundle the plasmid I designed with the corresponding downstream services?

  GenScript is committed to providing one-stop services. You can find the entry for downstream services corresponding to your designed vector on the design completed page, allowing you to make combined purchases, such as LVV vectors and LVV packaging services.

• 6. How to place bulk orders?

  We support placing bulk orders for multiple designs. Please first create several drafts and proceed to the vector completed page. Finally, click "Order" and select the designs you wish to purchase in the Batch Order Popup to complete the order integration.

• 7. What is the ITR Guarantee Service?

  ITR Guarantee Service is a specialized production process designed to ensure the integrity of your ITR sequence and coupled with sequencing to confirm ITR integrity. Good ITR integrity is essential for efficient rAAV packaging.

  The AAV application vector backbone comes with ITR sequences. We recommend selecting the ITR Guarantee service on the Plasmidprep Specifications Page to ensure the efficiency of your downstream packaging.