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TCR targets validation through

TCR targets validation through
T cell activation

Get An Inside Look At TCR Targets Validation Through T Cell Activation Get An Inside Look

Webinar Details

Date and Time: Tuesday May 11 14:15 (BST) / 15:15 (CEST) / 09:15 (EDT) / 06:15 (PDT) Title: TCR targets validation through T cell activation
Speaker: Anna Pasetto, Assistant Professor/Managing Director Pre-GMP facility of Karolinska Institutet.

Speaker Information:

Speaker Biography Anna Pasetto

Assistant Professor/Managing Director Pre-GMP facility of Karolinska Institutet

Dr. Pasetto joined the Karolinska Institutet in 2018 as assistant professor (biträdande universitetslektor) and managing director of the pre-GMP facility in the department of Laboratory Medicine. She received the Master Degree in Molecular Biotechnology in 2007 from Alma Mater Studiorum Bologna University, Italy. She then moved to the Karolinska Institutet where she received the PhD in 2012. She joined the laboratory of Dr. Steven Rosenberg at the National Cancer Institute, NIH in 2013 and her research was focused on the isolation of TCR genes from mutation-reactive tumor infiltrating lymphocytes in metastatic solid cancers.

Abstract

Neoantigens are considered attractive targets for cancer immunotherapy, but how to identify the most immunogenic or the most relevant for clinical response is still matter of debate in the research field. During this webcast we will provide the background on the most successful approaches that led to the identification of immunogenic neoantigens for cancer treatment. We will also discuss limitations and potential improvement to the discovery approach.

Key Takeaways