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Using Regular Porous Membrane-Based Blood−Brain Barrier Model to Screen Brain-Targeted Drugs with Nanochannel Electrochemistry
Authors: Yafeng Wu,Zixuan Chen,Fengxiang Chen,Juan Su,Jianyu Han,Songqin Liu
Journal: Anal Chem
PubMed ID: 40183921
Doi: 10.1021/acs.analchem.5c00365
Products & Services: Peptide Synthesis   
Peptide-conjugated alginate fiber: A skeletal muscle regenerative scaffold
Authors: Yajun Li, Yueren Wu, Tong Wu, Can Zhang, Jianwu Dai, Jianping Tang, Lin Li, Liyang Shi
Journal: Carbohydrate Polymers
PubMed ID: 39978892
Doi: 10.1016/j.carbpol.2025.123299
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Authors: Alexander J Garvin, Alexander J Lanz, George E Ronson, Matthew J W Mackintosh, Katarzyna Starowicz, Alexandra K Walker, Yara Aghabi, Hannah MacKay, Ruth M Densham, Jai S Bhachoo, Aneika C Leney, Joanna R Morris
Journal: Mol Cell
PubMed ID: 40054443
Doi: 10.1016/j.molcel.2025.02.004
Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase
Authors: Renier H P van Neer, Patricia K Dranchak, Mahesh Aitha, Lijun Liu, Emma K Carlson, Isabella E Jacobsen, Kevin Battaile, Yuhong Fang, Dingyin Tao, Ganesha Rai, Janak Padia, Scott Lovell, Hiroaki Suga, James Inglese
Journal: ACS Infectious Diseases
PubMed ID: 39903128
Doi: 10.1021/acsinfecdis.4c00798
Products & Services: Peptide Synthesis   Plasmid DNA Preparation   
Self-assembly GSH response based Buforin IIb-Olaparib nanocombination synergistically promotes DNA damage for prostate cancer immunotherapy
Authors: Maosong Hu , Yuyu Zhu , Xinyi Tang , Jing Xu , Hanbin Ma , Zhihan Chen , Duo Chen , Wenyuan Wu , Xialin Chen , Rongrong He , Jing Zhou , Jinao Duan , Weiguo Chen , Hongyue Ma
Journal: Chemical Engineering Journal
Doi: 10.1016/j.cej.2025.160862
Products & Services: Peptide Synthesis   
Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors
Authors: Hudie Wei, Haolan Wang, Shuang Xiang, Jiaqi Wang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Xiaoyun Lu, Yongheng Chen
Journal: Cell Death Differ
PubMed ID: 39901037
Doi: 10.1038/s41418-025-01454-2
Products & Services: Peptide Synthesis   
Structures of HCoV-OC43 HR1 Domain in Complex with Cognate HR2 or Analogue EK1 Peptide
Authors: Xiuxiu He, Huanzhen Liu, Guang Yang, Lei Yan
Journal: Viruses-Basel
PubMed ID: 40143271
Doi: 10.3390/v17030343
Products & Services: Peptide Synthesis   
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
Authors: Chang Peng, Haowen Jiang, Liya Jing, Wenhua Yang, Xiaotong Guan, Hanlin Wang, Sike Yu, Yutang Cao, Min Wang, Huan Ma, Zan Lv, Hongyu Gu, Chunmei Xia, Xiaozhen Guo, Bin Sun, Aili Wang, Cen Xie, Wenbiao Wu, Luyiyi Lu, Jiayi Song, Saifei Lei, Rui Wu, Yi Zang, Erjiang Tang, Jia Li
Journal: Nat Commun
PubMed ID: 39966410
Doi: 10.1038/s41467-025-57044-w
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
Authors: Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M McAloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy
Journal: Proc Natl Acad Sci U S A
PubMed ID: 39964718
Doi: 10.1073/pnas.2420961122
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Phosphorylation of PIP2;7 by CPK28 or Phytophthora kinase effectors dampens pattern-triggered immunity in Arabidopsis
Authors: Hai Zhu, Yazhou Bao, Hao Peng, Xianglan Li, Weiye Pan, Yufeng Yang, Zifei Kuang, Peiyun Ji, Jinding Liu, Danyu Shen, Gan Ai, Daolong Dou
Journal: plant communications
PubMed ID: 39277790
Doi: 10.1016/j.xplc.2024.101135
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